Zobrazeno 71 - 80
of 355
pro vyhledávání: ''
Autor:
Valeria Lifke, Oskar Hansson, John Q. Trojanowski, Niklas Mattsson, Leslie M. Shaw, Jon B. Toledo, Udo Eichenlaub, Katharina Buck, Simone Wahl, Kaj Blennow, Erik Stomrud, Maryline Simon
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
We evaluated the performance of CSF biomarkers for predicting risk of clinical decline and conversion to dementia in non-demented patients with cognitive symptoms. CSF samples from patients in two multicentre longitudinal studies (ADNI, n = 619; BioF
Autor:
Tzu-Hang Yuan, Hsiang-Yuan Yeh, Pei-Huan Chuang, Huei-Wen Chen, You-Tien Tsai, Chia-Ter Chao, Jenq-Wen Huang
Publikováno v:
Cell Death Discovery, Vol 5, Iss 1, Pp 1-11 (2019)
Cell Death Discovery
Cell Death Discovery
Vascular calcification (VC) is highly prevalent in patients with advanced age, or those with chronic kidney disease and diabetes, accounting for substantial global cardiovascular burden. The pathophysiology of VC involves active mineral deposition by
Autor:
Corrado Priami, Melissa J. Morine, Valeria Savoca, Karla Misselbeck, Silvia Parolo, Pranami Bora, Maria Caterina Mione, Francesca Lorenzini, Enrico Domenici, Lorena Leonardelli
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Metabolic syndrome is a pathological condition characterized by obesity, hyperglycemia, hypertension, elevated levels of triglycerides and low levels of high-density lipoprotein cholesterol that increase cardiovascular disease risk and type 2 diabete
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
We establish a compartmental model to study the transmission of Zika virus disease including spread through sexual contacts and the role of asymptomatic carriers. To incorporate the impact of the seasonality of weather on the spread of Zika, we apply
Autor:
Andrej Vogler, Hedi Peterson, Tea Lanišnik Rižner, René Wenzl, Tamara Knific, Manuela Gstöttner, Dmytro Fishman
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Endometriosis is a common gynaecological condition characterized by severe pelvic pain and/or infertility. The combination of nonspecific symptoms and invasive laparoscopic diagnostics have prompted researchers to evaluate potential biomarkers that w
Autor:
I McLachlan, Iain J. McKendrick, Glenn Marion, Thibaud Porphyre, Ian Handel, B.M. deC. Bronsvoort
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
McLachlan, I, Marion, G, McKendrick, I J, Porphyre, T, Handel, I & Bronsvoort, M 2019, ' Endemic foot and mouth disease : pastoral in-herd disease dynamics in sub-Saharan Africa ', Scientific Reports, vol. 9, no. 1, 17349 . https://doi.org/10.1038/s41598-019-53658-5
Scientific Reports
McLachlan, I, Marion, G, McKendrick, I J, Porphyre, T, Handel, I & Bronsvoort, M 2019, ' Endemic foot and mouth disease : pastoral in-herd disease dynamics in sub-Saharan Africa ', Scientific Reports, vol. 9, no. 1, 17349 . https://doi.org/10.1038/s41598-019-53658-5
Foot and mouth disease (FMD) burden disproportionally affects Africa where it is considered endemic. Smallholder livestock keepers experience significant losses due to disease, but the dynamics and mechanisms underlying persistence at the herd-level
Publikováno v:
Cell Death and Disease, Vol 10, Iss 11, Pp 1-8 (2019)
Cell Death & Disease
Cell Death & Disease
The vascular system of the spinal cord is particularly complex and vulnerable. Damage to the main vessels or alterations to the regulation of blood flow will result in a reduction or temporary cessation of blood supply. The resulting tissue hypoxia m
Autor:
Mustafa Ascha, Jill S. Barnholtz-Sloan, Andrew E Sloan, Jacqueline Wang, Carol Kruchko, Priya Kumthekar
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Bevacizumab is FDA-approved in the treatment of primary brain tumors, but its efficacy in patients with brain metastases could be better-studied. This study examines a population of non-small cell lung cancer (NSCLC) patients with synchronous brain m
Autor:
Yun Kyu Oh, Hyunsuk Kim, Nayoung K.D. Kim, Hyunho Kim, Kyu Beck Lee, Hyun Seob Lee, Woong-Yang Park, Hyunjin Ryu, Hayne Cho Park, Young Hwan Hwang, Chung Lee, Curie Ahn, Jongho Heo, Kook Hwan Oh
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Autosomal dominant polycystic kidney disease (ADPKD) is one of the main causes of end-stage renal disease (ESRD). Genetic information is of the utmost importance in understanding pathogenesis of ADPKD. Therefore, this study aimed to demonstrate the g
Autor:
Valeria Dimitrova, Ella Atlas
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Breast cancer is one of the most common cancers diagnosed in women worldwide. Genetic predisposition, such as breast cancer 1 (BRCA1) mutations, account for a minor percentage of the total breast cancer incidences. And thus, many life style factors h