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Autor:
Yan-Hong Li, Bin-Bin Fang, Xiao-Mei Li, Xiao-Ming Gao, Fen Liu, Jun-Yi Luo, Ting Tian, Yi-Ning Yang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Myocardial infarction (MI), the leading cause of mortality and disability worldwide, is a disease in which multiple environmental and genetic factors are involved. Recently, researches suggested that insertion/deletion (ins/del) variation of NFKB1 ge
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, 10(1). NATURE RESEARCH
Scientific Reports
Scientific Reports, 10(1)
Scientific Reports, 10(1). NATURE RESEARCH
Scientific Reports
Scientific Reports, 10(1)
Iron accumulation in the brain is a phenomenon common to many neurodegenerative diseases, perhaps most notably Alzheimer’s disease (AD).We present here magnetic analyses of post-mortem brain tissue of patients who had severe Alzheimer’s disease,
Autor:
Amin Marghalani, Wael Yaghmoor, Isabel Carreras, Jae-Yong Ahn, Christina M. Tognoni, Danielle Stephens, Alpaslan Dedeoglu, Alpdogan Kantarci
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Periodontal disease (PD) has been suggested to be a risk factor for Alzheimer’s disease (AD). We tested the impact of ligature-induced PD on 5xFAD mice and WT littermates. At baseline, 5xFAD mice presented significant alveolar bone loss compared to
Autor:
Maria Gavriatopoulou, Lia-Angela Moulopoulos, Evangelos Terpos, Nikolaos Kanellias, Andriani Βoultadaki, Efstathios Kastritis, Panagiotis Malandrakis, Ioannis Ntanasis-Stathopoulos, Magdalini Migkou, Charis Bourgioti, Despina Fotiou, Meletios A. Dimopoulos, Evangelos Eleutherakis-Papaiakovou, Vassilis Koutoulidis
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 9, Pp 1-7 (2020)
Blood Cancer Journal
Blood Cancer Journal
Introduction: Multiple myeloma (MM) is the second most common haematological malignancy and is characterized by bone marrow infiltration of monoclonal plasma cells and end-organ involvement. Smoldering MM (SMM) is an intermediate clinical entity betw
Autor:
Luigi Bonavina, Stefano Siboni, Veronica Lazzari, Daniele Bernardi, Emanuele Asti, Davide Ferrari
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
The magnetic sphincter augmentation (MSA) device has been proven safe and effective in controlling typical reflux symptoms and esophageal acid exposure for up to 6-year follow-up. Longer term outcomes have not been reported yet. A prospectively maint
Autor:
Vandana Sundaram, Christine H. Lee, Kaisha N. Benjamin, Teri A. Longacre, Kathleen Hornbacker, Pamela L. Kunz, Allison Zemek, Aidan Van Vleck, Timothy M. Horton, Justin P. Annes
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Neuroendocrine neoplasms (NENs) are rare epithelial tumors with heterogeneous and frequently unpredictable clinical behavior. Available biomarkers are insufficient to guide individual patient prognosis or therapy selection. Peptidylglycine α-amidati
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Physical exercise has been suggested to reduce the risk of developing Alzheimer’s disease (AD) as well as ameliorate the progression of the disease. However, we recently published results from two large epidemiological studies showing no such benef
Publikováno v:
Cell Death and Disease, Vol 10, Iss 11, Pp 1-8 (2019)
Cell Death & Disease
Cell Death & Disease
The vascular system of the spinal cord is particularly complex and vulnerable. Damage to the main vessels or alterations to the regulation of blood flow will result in a reduction or temporary cessation of blood supply. The resulting tissue hypoxia m
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Deficiency of laminin α2 chain leads to a severe form of congenital muscular dystrophy (LAMA2-CMD), and dystrophic symptoms progress rapidly in early childhood. Currently, there is no treatment for this detrimental disorder. Development of therapies
Autor:
Zhiwen Zhou, Xudong Mao, Qihong Cheng, Bin Hu, Jing Gao, Qing Gong, Yan Wu, Yue He, Xubin Xing, Ying Hu
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Hypovitaminosis D is associated with age-related illnesses, including hypertension, cardiovascular disease (CRVD), cerebrovascular disease (CAD) and type 2 diabetes mellitus (T2DM). In our retrospective observational study, blood samples of elderly h