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Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Translational Psychiatry
Translational Psychiatry
Funder: Stanley Medical Research Institute (SMRI); doi: https://doi.org/10.13039/100007123
Mental health disorders are a leading cause of disability worldwide. Challenges such as disease heterogeneity, incomplete characterization of the targets
Mental health disorders are a leading cause of disability worldwide. Challenges such as disease heterogeneity, incomplete characterization of the targets
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10, pp.19066. ⟨10.1101/751289⟩
Scientific Reports, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10, pp.19066. ⟨10.1101/751289⟩
Scientific Reports, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
The conditions used to describe the presence of an immune disease are often represented by interaction graphs. These informative, but intricate structures are susceptible to perturbations at different levels. The mode in which that perturbation occur
Autor:
Evguenia Nepotchatykh, Dawei Li, Christian Godbout, Corinne Leveau, Alain Moreau, Viorica Lascau-Coman, Shawn Lauzon, Lynda Chalder, Yanick Maillet, Renata Kosovskaia, Emi Kanamaru, Catherine Beaudin, Wesam Elremaly, Saadallah Bouhanik, Yaned Patricia Gaitan, Anita Franco, Iurie Caraus
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex chronic disease, rooted in multi-system dysfunctions characterized by unexplained debilitating fatigue. Post-exertional malaise (PEM), defined as the exacerbation of the patient
Autor:
Abrar Alhindi, Sean J. Udow, Colleen Millikin, Ji Hyun Ko, Mandana Modirrousta, Andrew Borys, Natalie Wright, Douglas E. Hobson, Julius B. M. Anang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Mild cognitive impairment (MCI) is common in Parkinson’s disease patients. However, its underlying mechanism is not well understood, which has hindered new treatment discoveries specific to MCI. The aim of this study was to investigate functional c
Autor:
Alireza Faridar, Shixiang Wen, Jason R. Thonhoff, Aaron D. Thome, David R. Beers, Weihua Zhao, Jinghong Wang, Daniel Neal, Stanley H. Appel
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Amyotrophic lateral sclerosis (ALS) is a multifactorial, multisystem pro-inflammatory neuromuscular disorder compromising muscle function resulting in death. Neuroinflammation is known to accelerate disease progression and accentuate disease severity
Autor:
Jinho Yang, Ju Kwang Choi, Yoon Jeong Park, Da Hyeon Choi, Jae Won Chang, Bon Seok Koo, Yoon Shin Park, Ho-Ryun Won, Won Hee Lee, Jiwon Park, Chan Oh, Ju Yeon Lee, Kyeong Eun Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 9, Pp 1564-1573 (2020)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Oral microbes have the capacity to spread throughout the gastrointestinal system and are strongly associated with multiple diseases. Given that tonsils are located between the oral cavity and the laryngopharynx at the gateway of the alimentary and re
Autor:
Cecilie L. Bager, M. H. Tang, Anne-Christine Bay-Jensen, Søren Brunak, P. Frederiksen, Morten A. Karsdal, Joseph P.M. Blair
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Blair, J P M, Bay-Jensen, A-C, Tang, M H, Frederiksen, P, Bager, C, Karsdal, M & Brunak, S 2020, ' Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis ', Scientific Reports, vol. 10, no. 1, 13975 . https://doi.org/10.1038/s41598-020-70942-x
Scientific Reports
Blair, J P M, Bay-Jensen, A-C, Tang, M H, Frederiksen, P, Bager, C, Karsdal, M & Brunak, S 2020, ' Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis ', Scientific Reports, vol. 10, no. 1, 13975 . https://doi.org/10.1038/s41598-020-70942-x
Rheumatoid arthritis (RA) is a chronic inflammatory disease with fluctuating course of progression. Despite substantial improvement in treatments in recent years, treatment response is still not guaranteed. The aim of this study was to identify varia
Autor:
Wei Yee Leong, Sunethra Gunasena, Ashley L. St. John, A S Athapathu, Irantha Karunaratna, Ting Lim, Chinmay K. Mantri, Manouri Senanayake, Annelies Wilder-Smith, Abhay P. S. Rathore
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Dengue induces a spectrum of severity in humans from the milder dengue fever to severe disease, or dengue hemorrhagic fever (DHF). Chymase is a candidate biomarker that may aid dengue prognosis. This prospective study aimed to identify whether warnin
Autor:
Kim Jung-Ho, Sang Nae Cho, Young Ae Kang, Bora Sim, Sang-Guk Lee, Young Mok Park, Yonggeun Cho, Hyejon Lee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Although tuberculosis (TB) is a severe health problem worldwide, the current diagnostic methods are far from optimal. Metabolomics is increasingly being used in the study of infectious diseases. We performed metabolome profiling to identify potential
Autor:
Ángeles Pallares, José Manuel Gallardo, Jesús Mateos, Cremildo Gomes-Maueia, Isabel Medina, Luis Anibarro, Tufária Mussá, Artur Nguilichane, Rajko Reljic, Olivia Estévez, Mónica Carrera, África González-Fernández
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Investigo. Repositorio Institucional de la Universidade de Vigo
Universidade de Vigo (UVigo)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
Investigo. Repositorio Institucional de la Universidade de Vigo
Universidade de Vigo (UVigo)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
12 pages, 7 figures, 2 tables.-- This article is licensed under a Creative Commons Attribution 4.0 International License
Tuberculosis (TB) is the most lethal infection among infectious diseases. The specific aim of this study was to establish pa
Tuberculosis (TB) is the most lethal infection among infectious diseases. The specific aim of this study was to establish pa