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of 82
pro vyhledávání: ''
Autor:
Jungwan Hong, Dongyeong Yoon, Youngpyo Nam, Tae Yong Lee, Kyoungho Suk, Kyung Suk Kim, Min Sung Kim, Sang Ryong Kim, Jong-Heon Kim, Ho-Won Lee, Pan-Woo Ko, Donggun Seo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Most cerebellar ataxias (CAs) are incurable neurological disorders, resulting in a lack of voluntary control by inflamed or damaged cerebellum. Although CA can be either directly or indirectly related to cerebellar inflammation, there is no suitable
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Silicon dioxide nanoparticles (SiO2NPs) are widely applied in industry, chemical, and cosmetics. SiO2NPs is known to induce pulmonary toxicity. In this study, we investigated the molecular mechanisms of SiO2NPs on pulmonary toxicity using a lung alve
Autor:
Leon E. Hugo, Andrii Slonchak, Morgan E. Freney, Alexander A. Khromykh, Gregor J. Devine, Julian D. J. Sng, Yin Xiang Setoh, Andrew F. van den Hurk, Francisco J. Torres, Roy A. Hall, Sonja Hall-Mendelin, Nias Y. G. Peng, Alberto A. Amarilla
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Flaviviruses, including Zika virus (ZIKV), utilise host mRNA degradation machinery to produce subgenomic flaviviral RNA (sfRNA). In mammalian hosts, this noncoding RNA facilitates replication and pathogenesis of flaviviruses by inhibiting IFN-signall
Autor:
Takayuki Suzuki, Chizuko Nishida, Aki Koike, Mitsuo Nunome, Yoichi Matsuda, Kenji Ichiyanagi, Manabu Koike, Keiji Kinoshita, Takeo Uemura
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology
Communications Biology
The Creeper (Cp) chicken is characterized by chondrodystrophy in Cp/+ heterozygotes and embryonic lethality in Cp/Cp homozygotes. However, the genes underlying the phenotypes have not been fully known. Here, we show that a 25 kb deletion on chromosom
Autor:
Vikas Chander, Gurudutta Gangenahalli
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Scientific Reports
Scientific Reports
Platelet microvesicles (pMVs) are submicron-sized heterogeneous vesicles released upon activation and contain several membrane receptors and proteins (CD41, CD61, CD62, CXCR4, PAR-1, etc.). We have revealed their ability to adhere to the triblock cop
Autor:
Ling Zhang, Bin Tian, Mujeeb Ur Rehman, Mingshu Wang, Dekang Zhu, Xinxin Zhao, Ying Wu, Qihui Luo, Shun Chen, Ling Zhu, Ni Zeng, Yunya Liu, Mafeng Liu, Renyong Jia, Yanling Yu, Zhengli Chen, Qiao Yang, Juan Huang, Yin Wang, Anchun Cheng, Xiaoyue Chen, Yalan Lai, Leichang Pan, Shaqiu Zhang, Zhiwen Xu
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Duck hepatitis A virus (DHAV) causes an infectious disease that mainly affects 1- to 4-week-old ducklings, resulting in considerable loss to the duck industry. Although there have been many studies on DHAV in recent years, the effects on host infecti
Autor:
A. Złotkowska, A. Andronowska
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Previous studies highlighted chemokines as potential factors regulating changes in the endometrium during early pregnancy. The current study aimed to screen the effects of a broad range of chemokines and indicate those that are involved in porcine lu
Autor:
Dongwei Liu, Jia-Hui Zhang, Xu-Tong Wang, Liu Fengxun, Zihao Zhao, Deng-Ke Jiang, Shaokang Pan, Zhangsuo Liu
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 8, Pp 1-15 (2019)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
The number of patients with diabetic nephropathy (DN) is still on the rise worldwide, and this requires the development of new therapeutic strategies. Recent reports have highlighted genetic factors in the treatment of DN. Herein, we aimed to study t
Autor:
Wenqian Cai, Masanari Umemura, Utako Yokoyama, Mayo Shigeta, Hiroshi Kiyonari, Huiling Jin, Kenji Suita, Takayuki Fujita, Junichi Sadoshima, Yuko Hidaka, Yoshihiro Ishikawa
Publikováno v:
Cell Death and Disease, Vol 10, Iss 8, Pp 1-14 (2019)
Cell Death & Disease
Cell Death & Disease
Prevention of cardiomyocyte death is an important therapeutic strategy for heart failure. In this study, we focused on translationally controlled tumor protein (TCTP), a highly conserved protein that is expressed ubiquitously in mammalian tissues, in
Autor:
Yacine Bareche, Isabelle Demeestere, Basile Stamatopoulos, Melody Devos, Chrysanthi Alexandri, Françoise Rothé
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific reports
Scientific Reports
Scientific reports
Cancer treatments as cyclophosphamide and its active metabolites are highly gonadotoxic leading to follicle apoptosis and depletion. Considering the risk of subsequent infertility, fertility preservation is recommended. Beside the germ cells and game