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pro vyhledávání: ''
Autor:
Ling Li, Quanxin Long, Li Liu, Xiaoyong Zhang, Yanqun Wang, Hong Zhu, Sheng Nie, Ailong Huang, Jinlin Hou, Xin Xu, Jian Sun, Fan Fan Hou, Jincun Zhao, Qinglang Zeng
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-7 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Our understanding of the protective immunity, particularly the long-term dynamics of neutralizing antibody (NAbs) response to SARS-CoV-2, is currently limited. We enrolled a cohort of 545 COVID-19 patients from Hubei, China, who were followed up up t
Autor:
Akira Fukuya, Yasuo Takahashi, Masahiro Hirakawa, Yasushi Sato, Hiroshi Miyamoto, Kyoko Hamaguchi, Tetsuji Takayama, Naoki Muguruma, Tamotsu Sagawa, Koshi Fujikawa, Koichi Okamoto
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The primary tumour location is an important prognostic factor for previously untreated metastatic colorectal cancer (mCRC). However, the predictive efficacies of primary tumour location, early tumour shrinkage (ETS), and depth of response (DpR) on mC
Autor:
Anna Ianza, Monica Ramello, Enrico Mini, Giandomenico Roviello, Alberto D'Angelo, Martina Catalano, Raffaele Conca, Lorenzo Dreoni, Roberto Petrioli, Stefania Nobili, Silvia Gasperoni, Michele Aieta
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Neutropenia is a common side effect associated with nab-paclitaxel gemcitabine (Nab-Gem) therapy. We retrospectively investigated the association between neutropenia induced by first-line Nab-Gem and survival in metastatic pancreatic carcinoma patien
Autor:
Jun-Hyeok Kang, Wen-Fang Cheng, Yoo-Young Lee, Yen-Ling Lai, Hyun Soo Kim, Kuan-Ting Kuo, Yu-Li Chen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Low-grade ovarian serous carcinoma (LGSOC) has clinical features different from high-grade serous ovarian carcinoma (HGSOC) accounting for the majority of epithelial ovarian cancer. Because of its rarity, previous studies have only focused on the hig
Autor:
Ruey Hsing Chou, Shao Sung Huang, Po Hsun Huang, Chun Chin Chang, Shing Jong Lin, Ya Wen Lu, Shen-Chih Wang, Yi Lin Tsai, Chin Sung Kuo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Galectin-1, a β-galactoside-binding lectin mediating inflammation and neovascularization, is reported to attenuate ventricular remodeling after myocardial infarction. But its role in stable coronary artery disease (CAD) has not been fully elucidated
Autor:
Bethania Fernandes, Massimo Roncalli, Corrado Tinterri, Alberto Testori, Giovanna Masci, Wolfgang Gatzemeier, Elisa Agostinetto, Agnese Losurdo, Rita De Sanctis, Valentina Errico, Armando Santoro, Rosalba Torrisi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Triple negative breast cancer (TNBC), usually presenting with a very aggressive phenotype, is a heterogeneous entity. We aim to discuss new biomarkers, suitable for prognostic and predictive purposes. We retrospectively collected clinical variables a
Autor:
Simon H. J. Brown, Fabian Kreilaus, Sarah E. Hancock, Andrew M. Jenner, Todd W. Mitchell, Kelly A. Newell, Gabrielle R. Phillips
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Huntington’s disease (HD) is an autosomal dominant neurodegenerative illness caused by a mutation in the huntingtin gene (HTT) and subsequent protein (mhtt), to which the brain shows a region-specific vulnerability. Disturbances in neural cholester
Autor:
Nicolas Flamand, Benoît Lamarche, Frédéric Raymond, Julie Perron, Lydiane Parent, Vincenzo Di Marzo, Alain Veilleux, Gabrielle Rochefort, Sébastien Lacroix, Cyril Martin, Sophie Castonguay-Paradis
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific reports (Nature Publishing Group) 10 (2020). doi:10.1038/s41598-020-72861-3
info:cnr-pdr/source/autori:Castonguay-Paradis, Sophie; Lacroix, Sebastien; Rochefort, Gabrielle; Parent, Lydiane; Perron, Julie; Martin, Cyril; Lamarche, Benoit; Raymond, Frederic; Flamand, Nicolas; Di Marzo, Vincenzo; Veilleux, Alain/titolo:Dietary fatty acid intake and gut microbiota determine circulating endocannabinoidome signaling beyond the effect of body fat/doi:10.1038%2Fs41598-020-72861-3/rivista:Scientific reports (Nature Publishing Group)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Scientific Reports
Scientific reports (Nature Publishing Group) 10 (2020). doi:10.1038/s41598-020-72861-3
info:cnr-pdr/source/autori:Castonguay-Paradis, Sophie; Lacroix, Sebastien; Rochefort, Gabrielle; Parent, Lydiane; Perron, Julie; Martin, Cyril; Lamarche, Benoit; Raymond, Frederic; Flamand, Nicolas; Di Marzo, Vincenzo; Veilleux, Alain/titolo:Dietary fatty acid intake and gut microbiota determine circulating endocannabinoidome signaling beyond the effect of body fat/doi:10.1038%2Fs41598-020-72861-3/rivista:Scientific reports (Nature Publishing Group)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Scientific Reports
The endocannabinoidome encompasses several fatty acid (FA)-derived mediators, including the endocannabinoid anandamide (AEA) and 2-arachidonoyl-glycerol (2-AG), which served as targets for anti-obesity drug development, and their congener N-acyl-etha
Autor:
Yusuke Tsuchimoto, Masahiro Matsui, Akira Asai, Kazuhisa Uchiyama, Kazuhide Higuchi, Yoshihiro Inoue, Hideko Ohama, Tomohiro Nishikawa, Norio Okamoto, Keisuke Yokohama, Shinya Fukunishi, Hidetaka Yasuoka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Immune-related adverse events (irAEs) are induced by immune checkpoint inhibitors (ICIs). Liver is one of the main target organs which irAEs occur and we investigated the influence of liver dysfunction on prognosis of patients after ICIs. From July 2
Autor:
Tingting Su, Shuang Ren, Bixun Li, Wei-Yuan Wei, Cheng-En Deng, Lu-Huai Feng, Zhenhua Yang, Kunpeng Bu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Colorectal cancer remains a major health burden worldwide and is closely related to type 2 diabetes. This study aimed to develop and validate a colorectal cancer risk prediction model to identify high-risk individuals with type 2 diabetes. Records of