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Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports
Scientific Reports
Bovine tuberculosis (bTB), a zoonosis mainly caused by Mycobacterium bovis has severe socio-economic consequences and impact on animal health. Host–pathogen interactions during M. bovis infection are poorly understood, especially early events which
Autor:
Yijian Li, Xiangfeng Liu, Guangdi Li, Huiling Li, Jian Pan, Bohao Liu, Yunchang Yuan, Xiaozhou Li, Peilin Zheng, Xudong Xiang, Xiangping Chai, Zhengyu Peng, Zhibiao He, Feng Liu, Hongliang Zhang, Dongshan Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Recent studies have reported that upregulation of disulfide-bond A oxidoreductase-like protein (DsbA-L) prevented lipid-induced renal injury in diabetic nephropathy (DN). However, the role and regulation of proximal tubular DsbA-L for renal tubuloint
Autor:
Wei Xia, Xue Yin, Xue-fei Zhu, Bingyu Zhang, Weiming Liu, Peirong Lu, Chi Ren, Lei Chen, Gaoqin Liu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Wet age-related macular degeneration (AMD), which can cause progressive blindness, is characterised by choroid neovascularization (CNV) in the macular area. Although close attention has been paid to AMD, and anti-vascular endothelial growth factor (V
Autor:
Youn-Ho Lee, Jina Oh, Young-Joon Lee, Sae-Kwang Ku, Phil Hyun Song, Choong-Gon Kim, Dae-Geon Lee, Chang-Hyun Song
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Balneotherapy is a common non-pharmacological treatment for osteoarthritis (OA), however, the efficacy is controversial in knee OA. Jeju magma-seawater (JMS) has high contents of various minerals, which has anti-inflammatory and antioxidant propertie
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific Reports
RAW 264.7 cells and HUVECs were compared to evaluate the effects of dialyzed coffee extract (DCE) and artificial coffee (AC). Immunoprecipitation high performance liquid chromatography (IP-HPLC) showed DCE-2.5- (equivalent to 2.5 cups of coffee a day
Autor:
Yin Li, Nan lan, Xiefang Yuan, Zhigang Liu, Xiang He, Xing Wang, Xi Dai, Xiaoyun Wang, Bin Niu, Guoping Li, Dehong Wu, Yun Zhang, Junyi Wang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Constant exposure to allergen triggers destructive type 2 cell-mediated inflammation. The effect of allergen specific immunotherapy (SIT) in maintaining airway epithelial barrier function in asthma remains unknown. In the current study, we showed tha
Autor:
Xiexing Wu, Mo Zhu, Yunxia Tao, Huilin Yang, Jiawei Shi, Dechun Geng, Liangliang Wang, Wei Zhou, Xiaobin Guo, Yu Liu, Haiqing Mao
Publikováno v:
Cell Death and Disease, Vol 9, Iss 2, Pp 1-11 (2018)
Cell Death & Disease
Cell Death & Disease
Intervertebral disc degeneration (IVDD) is one of the key predisposing factors for low back pain. Although the exact mechanism remains unclear, inflammatory response and nucleus pulposus (NP) apoptosis are known to play important roles in this proces
CD52 inhibits Toll-like receptor activation of NF-κB and triggers apoptosis to suppress inflammation
Autor:
Esther Bandala-Sanchez, John M. Wentworth, Yuxia Zhang, Leonard C. Harrison, Timothy E. Adams, James E Vince, Swarna L Vijayaraj, Alana M. Neale, Robert J.J. O'Donoghue, Kate E. Lawlor, Maryam Rashidi
Soluble CD52 is a small glycoprotein that suppresses T-cell activation, but its effect on innate immune cell function is unknown. Here we demonstrate that soluble CD52 inhibits Toll-like receptor and tumor necrosis factor receptor signaling to limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa048f048ae761a062e0af008dbff756
https://europepmc.org/articles/PMC5762852/
https://europepmc.org/articles/PMC5762852/
Autor:
S. Stojanovic, Gordana Kocic, Andrija Smelcerovic, Katarina Tomovic, Miodrag Čolić, Andrej Veljkovic, Hristina Kocic, Dusan Mihajlovic
Publikováno v:
Scientific Reports
The aim of this study was the evaluation of 15 days dietary regimen of depurinized (DP) milk (obtained using our patented technological procedures) or 1.5% fat UHT milk instead of standard chow diet, on rat thymus and bone marrow MyD88/Akt/p38, NF-κ
In order to establish infection, intra-macrophage parasite Leishmania donovani needs to inhibit host defense parameters like inflammatory cytokine production and apoptosis. In the present study, we demonstrate that the parasite achieves both by explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07f2f5efffe804940fb9b5c58ca36a5
https://europepmc.org/articles/PMC5071566/
https://europepmc.org/articles/PMC5071566/