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Autor:
Wan Seok Kang, Meeyoung Cho, Hye-jin Kang, Goo Taeg Oh, Mi Ra Kim, Hyang Hee Cho, Bo Gyeong Kang, Soo Yeon Lim, Youngkeun Ahn, Ju Hee Jun, Yong Sook Kim, Hye yun Jeong, Dong Im Cho
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
Resistin-like alpha (Retnla) is a member of the resistin family and known to modulate fibrosis and inflammation. Here, we investigated the role of Retnla in the cardiac injury model. Myocardial infarction (MI) was induced in wild type (WT), Retnla kn
Autor:
Yonggang Ma, Jia Li, Shiqing Liu, Yan Zhou, Ming Deng, Zhonghui Chen, Yubiao Zhang, Yaming Li, Jianghua Ming, Bochun Li
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Cell Death Discovery
Cell Death Discovery
MicroRNAs (miRNAs) encapsulated within exosomes can serve as essential regulators of intercellular communication and represent promising biomarkers of several aging-associated disorders. However, the relationship between exosomal miRNAs and osteoarth
Autor:
Xiaohua Gong, Rongrong Le, Xiaojun Chen, Ke Xu, Shi Yujuan, Hongjin Chen, Xiaozhong Huang, Zimiao Chen, Gu Xuemei, Qihan Zhu, Feixia Shen, Chen Xiong
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to inhibit inflammation in macrophages. Herein, we investigated the ef
Autor:
Jie-hui Tan, Jia Xu, Guo-wei Zhang, Yang-chen Jin, Min Luo, Xue-mei Chen, Jun-ling Zeng, Lei Zhou, Shu-ji Li, Rong-chang Cao, Guo-dong Hu, Jin Jin, Jia-yu Lin, Zhao-chang Qi, Huo-ji Chen, Zhi-tao Zhou
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
Treatment of acute pancreatitis (AP) and chronic pancreatitis (CP) remains problematic due to a lack of knowledge about disease-specific regulatory targets and mechanisms. The purpose of this study was to screen proteins related to endoplasmic reticu
Publikováno v:
Cell Death and Disease, Vol 11, Iss 8, Pp 1-18 (2020)
Cell Death & Disease
Cell Death & Disease
Apoptotic cell clearance by phagocytes is a fundamental process during development, homeostasis and the resolution of inflammation. However, the demands placed on phagocytic cells such as macrophages by this process, and the limitations these interac
Autor:
Olga Stenina-Adognravi, Edward F. Plow, Dmitry Solovjev, Irene Krukovets, Dmitriy Verbovetskiy, Chioma Obiako, Jiahui Wu, Mohammed Tanjimur Rahman, Santoshi Muppala
Publikováno v:
Cell Death and Disease, Vol 11, Iss 1, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Thrombospondin-4 (TSP-4) attracted renewed attention recently as a result of assignment of new functions to this matricellular protein in cardiovascular, muscular, and nervous systems. We have previously reported that TSP-4 promotes local vascular in
Autor:
Qiaona Niu, Ying Liao, Cuiping Song, Chan Ding, Chunchun Meng, Yanrong Li, Lei Tan, Xusheng Qiu, Sun Yingjie, Weiyu Jiang
Publikováno v:
Cell Death and Disease, Vol 10, Iss 12, Pp 1-15 (2019)
Cell Death & Disease
Cell Death & Disease
Newcastle disease virus (NDV) causes severe infectious disease in poultry and selectively kills tumor cells, by inducing apoptosis and cytokines secretion. In this report, we study the mechanisms underlying NDV-induced apoptosis by investigating the
Publikováno v:
Cell Death and Disease, Vol 10, Iss 10, Pp 1-18 (2019)
Cell Death & Disease
Cell Death & Disease
Background: Mucosal epithelial apoptosis with non-specific inflammation is an essential pathological characteristic in portal hypertensive gastropathy (PHG). However, whether a coordinated crosstalk between myeloid cells and epithelial cells involved
Autor:
Yasuyoshi Ueki, Ndona N. Nsumu, Xuanan Li, Shui Qing Ye, Mark W. Lee, Guanghua Lei, Daniel P. Heruth, Shamima Islam, Li Qin Zhang, Min Xiong
Publikováno v:
Cell Death Discovery, Vol 5, Iss 1, Pp 1-13 (2019)
Cell Death Discovery
Cell Death Discovery
Nicotinamide phosphoribosyltransferase (NAMPT) functions in NAD synthesis, apoptosis, and inflammation. Dysregulation of NAMPT has been associated with several inflammatory diseases, including rheumatoid arthritis (RA). The purpose of this study was
Publikováno v:
Cell Death and Disease, Vol 9, Iss 12, Pp 1-13 (2018)
Cell Death & Disease
Cell Death & Disease
This is the first study to investigate the hepatoprotective effect of CQ on acute liver injury caused by carbon tetrachloride (CCl4) in a murine model and the underlying molecular mechanisms. Ninety-six mice were randomly divided into the control (n