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Autor:
Lan-Hsiang Chien, Hung-Jung Lin, Chien-Chin Hsu, Chien-Cheng Huang, Ching-Ping Chang, Chung-Ching Chio, Mao-Tsun Lin
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
To date, there is no good evidence that intestine epithelial cells (IEC) affected by ischemia/reperfusion (I/R) injury are able to cause cortical neuron injury directly. Additionally, it remains unclear whether the neuronal damage caused by I/R injur
Publikováno v:
Cell Death and Disease, Vol 10, Iss 10, Pp 1-18 (2019)
Cell Death & Disease
Cell Death & Disease
Background: Mucosal epithelial apoptosis with non-specific inflammation is an essential pathological characteristic in portal hypertensive gastropathy (PHG). However, whether a coordinated crosstalk between myeloid cells and epithelial cells involved
Autor:
Tae Il Kim, Soo Jung Park, Jae Hee Cheon, Seung Won Kim, Jae Hyeon Kim, Won Ho Kim, Sujeong Hong, Hyun Jung Lee, Je-Wook Yu, Inhwa Hwang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
The pathogenesis of intestinal Behçet’s disease (BD) remains poorly understood. Therefore, we aimed to discover and validate biomarkers using proteomics analysis and subsequent functional studies. After two-dimensional electrophoresis, candidate p
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Salpingitis is a common cause for subfertility and infertility both in humans and animals. However, the effects of salpingitis on tubal function and reproductive success are largely unknown. Therefore we set out to investigate the effects of inflamma
Autor:
Jia Hung Liou, Jiu Yao Wang, Yi Giien Tsai, Hai Lun Sun, Yung Sung Wen, Kuender D. Yang, Ching-Yuang Lin
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Autophagy plays a major role in defending against oxidative stress in respiratory epithelial cells. The complement regulatory protein CD46 can enhance autophagy and decrease local complement activation at sites of inflammation. This study investigate
Autor:
Irene H. Heijink, Martijn C. Nawijn, Victor Guryev, Simon D. Pouwels, Alen Faiz, Cornelis J. Vermeulen, Maarten van den Berge
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports, 8(1):12426. Nature Publishing Group
Scientific Reports
Scientific Reports, 8(1):12426. Nature Publishing Group
Scientific Reports
Cigarette smoking is a major risk factor for the inflammatory disease, chronic obstructive pulmonary disease (COPD). The mechanism by which cigarette smoke (CS) induces chronic lung inflammation is still largely unknown. We hypothesize that immunogen
Autor:
Toru Nyunoya, Ji Hyeok Lee, Andrew J. Jang, You-Jin Jeon, Raymond L. Benza, Steve Kye, Michael J. Passineau, Mari Yotsu-Yamashita, Joodong Park
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Extract of the Japanese apricot (JAE) has biological properties as an antioxidant and anti-inflammatory agent. We hypothesized that JAE might exert therapeutic effects on cigarette smoke (CS)-induced DNA damage and cytotoxicity. In this study, we fou
Autor:
Yin Li, Nan lan, Xiefang Yuan, Zhigang Liu, Xiang He, Xing Wang, Xi Dai, Xiaoyun Wang, Bin Niu, Guoping Li, Dehong Wu, Yun Zhang, Junyi Wang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Constant exposure to allergen triggers destructive type 2 cell-mediated inflammation. The effect of allergen specific immunotherapy (SIT) in maintaining airway epithelial barrier function in asthma remains unknown. In the current study, we showed tha
Autor:
Jennifer Martinez, Thomas H. Oguin
Recognition and removal of apoptotic cells by professional phagocytes, including dendritic cells and macrophages, preserves immune self-tolerance and prevents chronic inflammation and autoimmune pathologies. The diverse array of phagocytes that resid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a3b2bff00160c67d154dabab02e0c0
https://europepmc.org/articles/PMC5563984/
https://europepmc.org/articles/PMC5563984/
Publikováno v:
Scientific Reports
The role of p53 in renal fibrosis has recently been suggested, however, its function remains controversial and the underlying mechanism is unclear. Here, we show that pharmacological and genetic blockade of p53 attenuated renal interstitial fibrosis,