Zobrazeno 1 - 10
of 48
pro vyhledávání: ''
Autor:
Feng Xinxin, Hailin Jia, Dongxiao Cai, Jing Wang, Huanlong Liu, Diandong Jiang, Bo Han, Li Zhang, Wei Sun
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-18 (2021)
Cell Death & Disease
Cell Death & Disease
Myocarditis (MC) is a common, potentially life-threatening inflammatory disease of the myocardium. A growing body of evidence has shown that mitogen-activated protein kinase 14 (MAPK14) participates in the pathogenesis of MC. However, the upstream re
Autor:
Alexei Verkhratsky, Peter Illes, Na Xie, Zhao Huang, Yong Tang, Beáta Sperlágh, Shu-Guang Yu, Francesco Di Virgilio, Henning Ulrich, Alexey Semyanov, Canhua Huang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-20 (2021)
Signal Transduction and Targeted Therapy
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Signal Transduction and Targeted Therapy
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Purines and their derivatives, most notably adenosine and ATP, are the key molecules controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these purines support, as chemical messengers, purinergic transmission throughout ti
Autor:
Wan Seok Kang, Meeyoung Cho, Hye-jin Kang, Goo Taeg Oh, Mi Ra Kim, Hyang Hee Cho, Bo Gyeong Kang, Soo Yeon Lim, Youngkeun Ahn, Ju Hee Jun, Yong Sook Kim, Hye yun Jeong, Dong Im Cho
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
Resistin-like alpha (Retnla) is a member of the resistin family and known to modulate fibrosis and inflammation. Here, we investigated the role of Retnla in the cardiac injury model. Myocardial infarction (MI) was induced in wild type (WT), Retnla kn
Autor:
Yonggang Ma, Jia Li, Shiqing Liu, Yan Zhou, Ming Deng, Zhonghui Chen, Yubiao Zhang, Yaming Li, Jianghua Ming, Bochun Li
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Cell Death Discovery
Cell Death Discovery
MicroRNAs (miRNAs) encapsulated within exosomes can serve as essential regulators of intercellular communication and represent promising biomarkers of several aging-associated disorders. However, the relationship between exosomal miRNAs and osteoarth
Autor:
Xiaohua Gong, Rongrong Le, Xiaojun Chen, Ke Xu, Shi Yujuan, Hongjin Chen, Xiaozhong Huang, Zimiao Chen, Gu Xuemei, Qihan Zhu, Feixia Shen, Chen Xiong
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to inhibit inflammation in macrophages. Herein, we investigated the ef
Autor:
Jie-hui Tan, Jia Xu, Guo-wei Zhang, Yang-chen Jin, Min Luo, Xue-mei Chen, Jun-ling Zeng, Lei Zhou, Shu-ji Li, Rong-chang Cao, Guo-dong Hu, Jin Jin, Jia-yu Lin, Zhao-chang Qi, Huo-ji Chen, Zhi-tao Zhou
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
Treatment of acute pancreatitis (AP) and chronic pancreatitis (CP) remains problematic due to a lack of knowledge about disease-specific regulatory targets and mechanisms. The purpose of this study was to screen proteins related to endoplasmic reticu
Autor:
Xuetao Cao, Ye Zhou, Suyuan Wang, Zhenyang Li, Nan Li, Jin Hou, Mu Wang, Kaiwei Jia, Yizhi Yu, Liyuan Zhang
Publikováno v:
Oncogenesis, Vol 9, Iss 10, Pp 1-14 (2020)
Oncogenesis
Oncogenesis
Hepatic apoptosis and the initiated liver inflammation play the initial roles in inflammation-induced hepatocarcinogenesis. Molecular mechanisms underlying the regulation of hepatocyte apoptosis and their roles in hepatocarcinogenesis have attracted
Autor:
Yijian Li, Xiangfeng Liu, Guangdi Li, Huiling Li, Jian Pan, Bohao Liu, Yunchang Yuan, Xiaozhou Li, Peilin Zheng, Xudong Xiang, Xiangping Chai, Zhengyu Peng, Zhibiao He, Feng Liu, Hongliang Zhang, Dongshan Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Recent studies have reported that upregulation of disulfide-bond A oxidoreductase-like protein (DsbA-L) prevented lipid-induced renal injury in diabetic nephropathy (DN). However, the role and regulation of proximal tubular DsbA-L for renal tubuloint
Publikováno v:
Cell Death and Disease, Vol 11, Iss 8, Pp 1-18 (2020)
Cell Death & Disease
Cell Death & Disease
Apoptotic cell clearance by phagocytes is a fundamental process during development, homeostasis and the resolution of inflammation. However, the demands placed on phagocytic cells such as macrophages by this process, and the limitations these interac
Autor:
Wei Xia, Xue Yin, Xue-fei Zhu, Bingyu Zhang, Weiming Liu, Peirong Lu, Chi Ren, Lei Chen, Gaoqin Liu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Wet age-related macular degeneration (AMD), which can cause progressive blindness, is characterised by choroid neovascularization (CNV) in the macular area. Although close attention has been paid to AMD, and anti-vascular endothelial growth factor (V