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Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Across the planet the biogeographic distribution of human cultural diversity tends to correlate positively with biodiversity. In this paper we focus on the biogeographic distribution of mammal species and human cultural diversity. We show that not on
Autor:
Kenji Kashiwagi, Yoko Iizuka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Health problems caused by airborne particulate matter with a diameter less than 2.5 (PM2.5), especially in the respiratory system, have become a worldwide problem, but the influence and mechanisms of PM2.5 on the ocular surface have not been sufficie
Autor:
John R. Mackey, Muba Taher, Parsin Haji Reza, Frank van Landeghem, Saad Abbasi, Deepak Dinakaran, Kevan Bell, Gilbert Bigras
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Histological visualizations are critical to clinical disease management and are fundamental to biological understanding. However, current approaches that rely on bright-field microscopy require extensive tissue preparation prior to imaging. These pro
Autor:
Yuko Tajima, Yoshito Kakihara, Yukina Kawagoe, Kotone Okuno, Yota Yamabe, Kanako Chikaoka, Daijiro Ueda, Tadasu K. Yamada, Mao Inoue, Tsutomu Sato, Takashi Hara
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Ambergris, a sperm whale metabolite, has long been used as a fragrance and traditional medication, but it is now rarely available. The odor components of ambergris result from the photooxidative degradation of the major component, ambrein. The pharma
Autor:
Marie Mita, Mary Arai, Yuki Hayasaka, Hiroshi Ueda, Tetsuya Kitaguchi, Takashi Tsuboi, Saki Tsuno, Mitsuharu Matsumoto, Mai Takizawa, Takami Chihara, Takeshi Ishihara, Kentaro Ishida, K Harada
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Glycolysis is the metabolic pathway that converts glucose into pyruvate, whereas fermentation can then produce lactate from pyruvate. Here, we developed single fluorescent protein (FP)-based lactate and pyruvate indicators with low EC50 for trace det
Autor:
Frank van den Elshout, Marc E. Lenburg, Wim Timens, Alen Faiz, Dirkje S. Postma, Corry-Anke Brandsma, Wim Boersma, Erica van der Wiel, Kai Imkamp, Sebastiaan J. Vroegop, Maarten van den Berge, Gerard H. Koppelman, Avrum Spira, Huib A. M. Kerstjens, Katrina Steiling, Henk R. Pasma, Ilse M. Boudewijn, Pascal Wielders, Irene H. Heijink, Khaled Mansour
Publikováno v:
Scientific Reports, 10(1):17415, 1-12. Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Hyperinflation contributes to dyspnea intensity in COPD. Little is known about the molecular mechanisms underlying hyperinflation and how inhaled corticosteroids (ICS) affect this important aspect of COPD pathophysiology. To investigate the effect of
Autor:
Michito Shimozuru, Hifumi Tsuruga, Tsutomu Mano, Takane Nose, Masanao Nakanishi, Masataka Shirayanagi, Mina Jimbo, Shinsuke Kasai, Masami Yamanaka, Yuri Shirane, Toshio Tsubota, Tsuyoshi Ishinazaka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Human habituation of large carnivores is becoming a serious problem that generates human–wildlife conflict, which often results in the removal of animals as nuisances. Although never tested, human habituation potentially reduces the fitness of adul
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
As a representative bioactive component in Brazil green propolis, Artepillin C (ArtC; 3, 5-diprenyl-4-hydroxycinnamic acid) has been reported a wide variety of physiological activities including anti-tumor, anti-inflammatory, and antimicrobial activi
Autor:
Wakana Nakane, Natsuki Kaminaga, Yoshikazu Kitano, Maaya Nishiko, Takeru Nakazato, Hidemasa Bono, Richard J. Simpson, Miho Nakano, Takuma Sakamoto, Hiroko Tabunoki, Kaoru Kinoshita, Isao Ogiwara, Hisashi Nakamura, Kikuo Iwabuchi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Phytophagous insect larvae feed on plants containing secondary metabolic products with biological activity against other predatory organisms. Phytophagous insects can use their specialised metabolic systems to covert these secondary metabolic product
Autor:
Mine-Hsine Wu, Chuan Shih, Hsiao-Fu Chang, Chun-Ping Chang, Lun K. Tsou, Shau-Hua Ueng, Shiu Hwa Yeh, Chiung-Tong Chen, Yi-Yu Ke, Jen-Shin Song, Sheng-Ren Chen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Machine learning is a well-known approach for virtual screening. Recently, deep learning, a machine learning algorithm in artificial neural networks, has been applied to the advancement of precision medicine and drug discovery. In this study, we perf