Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Oostra, Ben A."'
Autor:
Zillikens MC; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands., Demissie S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Hsu YH; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, Boston, MA, 02115, USA., Yerges-Armstrong LM; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Chou WC; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute, Cambridge, MA, 02142, USA., Stolk L; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands., Livshits G; Sackler Faculty of Medicine, Department of Anatomy and Anthropology, Tel Aviv University, Tel Aviv, 6997801, Israel.; Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Campus, London, WC2R 2LS, UK., Broer L; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Johnson T; Department of Medical Genetics, University of Lausanne, Lausanne, 1011, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland.; Centre Hospitalier Universitaire (CHUV), University Institute for Social and Preventive Medicine, Lausanne, 1010, Switzerland., Koller DL; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Kutalik Z; Department of Medical Genetics, University of Lausanne, Lausanne, 1011, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland.; Centre Hospitalier Universitaire (CHUV), University Institute for Social and Preventive Medicine, Lausanne, 1010, Switzerland., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK., Malkin I; Sackler Faculty of Medicine, Department of Anatomy and Anthropology, Tel Aviv University, Tel Aviv, 6997801, Israel., Ried JS; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Smith AV; Icelandic Heart Association, Kopavogur, 201, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Thorleifsson G; deCODE Genetics, Reykjavik, 101, Iceland., Vandenput L; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Hua Zhao J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK., Zhang W; Department Epidemiology and Biostatistics, School of Public Health, Imperial College, London, SW7 2AZ, UK.; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK., Aghdassi A; Department of Medicine A, University of Greifswald, Greifswald, 17489, Germany., Åkesson K; Department of Clinical Sciences, Lund University, Malmö, 22362, Sweden.; Department of Orthopedics, Skåne University Hospital, Malmö, S-205 02, Sweden., Amin N; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Baier LJ; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ, 85014, USA., Barroso I; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK.; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, CB2 OQQ, UK.; Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge Metabolic Research Laboratories, Cambridge, CB2 OQQ, UK., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA., Bertram L; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Experimental & Integrative Genomics, University of Lübeck, Lübeck, 23562, Germany.; School of Public Health, Faculty of Medicine, Imperial College London, London, W6 8RP, UK., Biffar R; Centre of Oral Health, Department of Prosthetic Dentistry, Gerodontology and Biomaterials, University of Greifswald, Greifswald, 17489, Germany., Bochud M; Centre Hospitalier Universitaire (CHUV), University Institute for Social and Preventive Medicine, Lausanne, 1010, Switzerland., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, MO, 63110, USA.; Division of Biostatistics, Washington University School of Medicine, St Louis, MO, 63110, USA., Buchman AS; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA., Byberg L; Department of Surgical Sciences, Uppsala University, Uppsala, 75185, Sweden., Campbell H; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, EH8 9AG, UK., Campos Obanda N; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands., Cauley JA; Department of Epidemiology Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Cawthon PM; California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA., Cederberg H; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Chen Z; Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, 85714, USA., Cho NH; Department of Preventive Medicine, Ajou University School of Medicine, Youngtong-Gu, Suwon, 16499, Korea., Jin Choi H; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea.; Department of Internal Medicine, Chungbuk National University Hospital, Cheongju Si, Korea., Claussnitzer M; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute, Cambridge, MA, 02142, USA.; Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, 02139, USA.; Institute of Human Genetics, MRI, Technische Universität München, Munich, 81675, Germany.; Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA., Collins F; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, Bethesda, MD, 20892, USA., Cummings SR; California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA., De Jager PL; Harvard Medical School, Boston, MA, 02115, USA.; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, 02142, USA., Demuth I; Lipid Clinic at the Interdisciplinary Metabolism Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, 13353, Germany.; Institute of Medical and Human Genetics, Charité - Universitätsmedizin Berlin, Berlin, 13353, Germany., Dhonukshe-Rutten RAM; Department of Human Nutrition, Wageningen University, PO Box 17, Wageningen, 6700 AA, The Netherlands., Diatchenko L; Alan Edwards Centre for Research on Pain, McGill University, Montreal, H3A 0G1, Canada.; Regional Center for Neurosensory Disorders, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Eiriksdottir G; Icelandic Heart Association, Kopavogur, 201, Iceland., Enneman AW; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands., Erdos M; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, Bethesda, MD, 20892, USA., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, 00014, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, 00014, Finland.; Folkhalsan Research Centre, Helsinki, 00250, Finland.; Vasa Central Hospital, Vasa, 65130, Finland.; National Institute for Health and Welfare, Helsinki, 00271, Finland., Eriksson J; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Estrada K; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Evans DS; California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, MO, 63110, USA., Fu M; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Garcia M; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute for Aging, Bethesda, MD, 20892, USA., Gieger C; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Girke T; Institute for Integrative Genome Biology, University of California, Riverside, CA, 92521, USA.; Department of Botany and Plant Sciences, University of California, Riverside, CA, 92521, USA., Glazer NL; Departments of Medicine and Epidemiology, Boston University School of Medicine and Public Health, Boston, MA, 02118, USA., Grallert H; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Department of Botany and Plant Sciences, University of California, Riverside, CA, 92521, USA.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; CCG Type 2 Diabetes, Helmholtz Zentrum München, Neuherberg, 85764, Germany.; CCG Nutrigenomics and Type 2 Diabetes. Helmholtz Zentrum München, Neuherberg, 85764, Germany., Grewal J; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Han BG; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, 28159, Korea., Hanson RL; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ, 85014, USA., Hayward C; MRC Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh, Scotland, EH4 2XU, UK., Hofman A; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Hoffman EP; Department of Pharmaceutical Sciences, SUNY Binghamton, Binghamton, NY, 13902, USA., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, 17487, Germany., Hsueh WC; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ, 85014, USA., Hubal MJ; Department of Exercise and Nutrition Sciences, George Washington University, Washington, DC, 20052, USA.; Research Center for Genetic Medicine, Children's National Medical Center, Washington, DC, 20052, USA., Hubbard A; Division of Biostatistics, School of Public Health, University of California, Berkeley, CA, 94720, USA., Huffman KM; Division of Rheumatology, Department of Medicine, Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Husted LB; Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, DK 8000, Denmark., Illig T; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Department of Human Genetics, Hannover Medical School, Hannover, 30625, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, 30625, Germany., Ingelsson E; Department of Medical Sciences, Uppsala University, Uppsala, 75185, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA., Ittermann T; Institute for Community Medicine, University of Greifswald, Greifswald, 17489, Germany., Jansson JO; Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE 405 30, Sweden., Jordan JM; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27517, USA., Jula A; National Institute for Health and Welfare, Helsinki, 00271, Finland., Karlsson M; Department of Clinical Sciences and Orthopaedics, Lund University, Skåne University Hospital SUS, Malmö, 22362, Sweden., Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Kilpeläinen TO; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK.; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Copenhagen, 2100, Denmark.; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Klopp N; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, 30625, Germany., Kloth JSL; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands., Koistinen HA; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, 00029, Finland.; Endocrinology, Abdominal Center, University of Helsinki and Helsinki University Central Hospital, Helsinki, 00029, Finland.; Department of Health, National Institute for Health and Welfare, Helsinki, 00271, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, 00290, Finland., Kraus WE; Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Kritchevsky S; Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Kuulasmaa T; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Lahti J; Institute of Behavioural Sciences, University of Helsinki, Helsinki, FI00014, Finland., Lang T; University of California San Francisco, San Francisco, CA, 94143, USA., Langdahl BL; Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, DK 8000, Denmark., Launer LJ; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute for Aging, Bethesda, MD, 20892, USA., Lee JY; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, 28159, Korea., Lerch MM; Department of Medicine A, University of Greifswald, Greifswald, 17489, Germany., Lewis JR; School of Medicine and Pharmacology, University of Western Australia, Perth, 6009, Australia.; Centre for Kidney Research, School of Public Health, University of Sydney, Sydney, 2006, Australia., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, 75185, Sweden., Lindgren C; Wellcome Trust Centre for Human Genetics, Oxford University, Oxford, OX3 7BN, UK., Liu Y; Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, 27517, USA., Liu T; Max Planck Institute for Molecular Genetics, Berlin, 14195, Germany.; Max Planck Institute for Human Development, Berlin, 14195, Germany., Liu Y; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27517, USA., Ljunggren Ö; Department of Medical Sciences, Uppsala University, Uppsala, 75185, Sweden., Lorentzon M; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Luben RN; Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Maixner W; Regional Center for Neurosensory Disorders, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., McGuigan FE; Department of Clinical Sciences, Lund University, Malmö, 22362, Sweden., Medina-Gomez C; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Meitinger T; Institute of Human Genetics, MRI, Technische Universität München, Munich, 81675, Germany.; Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Melhus H; Department of Medical Sciences, Uppsala University, Uppsala, 75185, Sweden., Mellström D; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Melov S; Buck Institute for Research on Aging, Novato, CA, 94945, USA.; Leonard Davis School of Gerontology, University of Southern California, LA, CA, 90089, USA., Michaëlsson K; Department of Surgical Sciences, Uppsala University, Uppsala, 75185, Sweden., Mitchell BD; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, 21201, USA., Morris AP; Wellcome Trust Centre for Human Genetics, Oxford University, Oxford, OX3 7BN, UK.; Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3BX, UK., Mosekilde L; Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, DK 8000, Denmark., Newman A; Center for Aging and Population Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Nielson CM; Oregon Health & Science University, Portland, OR, 97239, USA., O'Connell JR; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Oostra BA; Department of Clinical Genetics, Erasmus MC, Rotterdam, 300 CA, The Netherlands.; Centre for Medical Systems Biology and Netherlands Consortium on Healthy Aging, Leiden, RC2300, The Netherlands., Orwoll ES; Oregon Health & Science University, Portland, OR, 97239, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland.; Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, FI00014, Finland., Parker SCJ; Human Genetics and Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA., Peacock M; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Perola M; National Institute for Health and Welfare, Helsinki, 00271, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland.; Diabetes and Obesity Research Program, University of Helsinki, Helsinki, FI00014, Finland.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Polasek O; Faculty of Medicine, Department of Public Health, University of Split, Split, 21000, Croatia., Prince RL; School of Medicine and Pharmacology, University of Western Australia, Perth, 6009, Australia.; Department of Endocrinology and Diabetes, Sir Charles Gardiner Hospital, Perth, 6009, Australia., Räikkönen K; Institute of Behavioural Sciences, University of Helsinki, Helsinki, FI00014, Finland., Ralston SH; Molecular Medicine Centre, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, EH4 2XU, UK., Ripatti S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland.; Hjelt Institute, University of Helsinki, Helsinki, Finland.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK., Robbins JA; Department of Medicine, University of California at Davis, Sacramento, CA, 95817, USA., Rotter JI; Institute for Translational Genomic and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor UCLA Medical Center, Torrance, CA, 90502, USA., Rudan I; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, EH8 9AG, UK., Salomaa V; National Institute for Health and Welfare, Helsinki, 00271, Finland., Satterfield S; Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, 38163, USA., Schadt EE; Department of Genetics and Genomic Science, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Schipf S; Institute for Community Medicine, University of Greifswald, Greifswald, 17489, Germany., Scott L; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Sehmi J; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Shen J; Oregon Health & Science University, Portland, OR, 97239, USA., Soo Shin C; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea., Sigurdsson G; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; Department of Endocrinology and Metabolism, Landspitali, The National University Hospital of Iceland, Reykjavik, 101, Iceland., Smith S; Center for Translational Pain Medicine, Department of Anesthiology, Duke University Medical Center, Durham, NC, 27110, USA., Soranzo N; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK., Stančáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Steinhagen-Thiessen E; Lipid Clinic at the Interdisciplinary Metabolism Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, 13353, Germany., Streeten EA; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Geriatric Research and Education Clinical Center (GRECC) - Veterans Administration Medical Center, Baltimore, MD, 21201, USA., Styrkarsdottir U; deCODE Genetics, Reykjavik, 101, Iceland., Swart KMA; Department of Epidemiology and Biostatistics, and the EMGO Institute, VU University Medical Center, Amsterdam, BT1081, The Netherlands., Tan ST; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Tarnopolsky MA; Department of Medicine, McMaster University Medical Center, Hamilton, ON, Canada, L8N 3Z5., Thompson P; Department of Pathology, Stony Brook School of Medicine, Stony Brook, NY, 11794, USA., Thomson CA; Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, 85714, USA., Thorsteinsdottir U; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; deCODE Genetics, Reykjavik, 101, Iceland., Tikkanen E; National Institute for Health and Welfare, Helsinki, 00271, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland.; Molecular Medicine Centre, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, EH4 2XU, UK., Tranah GJ; California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA., Tuomilehto J; Vasa Central Hospital, Vasa, 65130, Finland.; Department of Neuroscience and Preventive Medicine, Danube-University Krems, Krems, 3500, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah, 12589, Saudi Arabia.; Dasman Diabetes Institute, Dasman, 15462, Kuwait., van Schoor NM; Department of Epidemiology and Biostatistics, and the EMGO Institute, VU University Medical Center, Amsterdam, BT1081, The Netherlands., Verma A; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK., Vollenweider P; Department of Medicine and Internal Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, CH-1011, Switzerland., Völzke H; Institute for Community Medicine, University of Greifswald, Greifswald, 17489, Germany., Wactawski-Wende J; Department of Epidemiology and Environmental Health, University at Buffalo, State University of New York, Buffalo, NY, 14214, USA., Walker M; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Weedon MN; Genetics of Complex Traits, University of Exeter Medical School, Exeter, EX1 2LU, UK., Welch R; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Wichmann HE; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich, 81377, Germany.; Institute of Medical Statistics and Epidemiology, Technical University, Munich, 81675, Germany., Widen E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland., Williams FMK; Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Campus, London, WC2R 2LS, UK., Wilson JF; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, EH8 9AG, UK.; MRC Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh, Scotland, EH4 2XU, UK., Wright NC; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Xie W; Genetics of Complex Traits, University of Exeter Medical School, Exeter, EX1 2LU, UK., Yu L; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA., Zhou Y; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Chambers JC; Department Epidemiology and Biostatistics, School of Public Health, Imperial College, London, SW7 2AZ, UK.; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; NIHR Cardiovascular Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, SW3 6NP, UK.; Imperial College Healthcare NHS Trust, London, W2 1NY, UK., Döring A; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., van Duijn CM; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands.; Centre for Medical Systems Biology and Netherlands Consortium on Healthy Aging, Leiden, RC2300, The Netherlands., Econs MJ; Department of Medicine and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Gudnason V; Icelandic Heart Association, Kopavogur, 201, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Kooner JS; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK.; Imperial College Healthcare NHS Trust, London, W2 1NY, UK., Psaty BM; Departments of Medicine, Epidemiology, and Health Services, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, 98101, USA.; Kaiser Permanente Washington Health Research Institute, Washington, Seattle, WA, 98101, USA., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Campus, London, WC2R 2LS, UK., Stefansson K; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; deCODE Genetics, Reykjavik, 101, Iceland., Rivadeneira F; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Uitterlinden AG; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK., Ossowski V; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ, 85014, USA., Waterworth D; Medical Genetics, GlaxoSmithKline, Philadelphia, PA, 19112, USA., Loos RJF; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Institute of Child Health and Development, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; The Genetics of Obesity and Related Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Karasik D; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, 1311502, Israel., Harris TB; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute for Aging, Bethesda, MD, 20892, USA., Ohlsson C; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Kiel DP; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA. kiel@hsl.harvard.edu.; Harvard Medical School, Boston, MA, 02115, USA. kiel@hsl.harvard.edu.; Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA. kiel@hsl.harvard.edu.
Publikováno v:
Nature communications [Nat Commun] 2017 Nov 07; Vol. 8 (1), pp. 1414. Date of Electronic Publication: 2017 Nov 07.
Autor:
Zillikens MC; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands., Demissie S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Hsu YH; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, Boston, MA, 02115, USA., Yerges-Armstrong LM; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Chou WC; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute, Cambridge, MA, 02142, USA., Stolk L; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands., Livshits G; Sackler Faculty of Medicine, Department of Anatomy and Anthropology, Tel Aviv University, Tel Aviv, 6997801, Israel.; Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Campus, London, WC2R 2LS, UK., Broer L; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Johnson T; Department of Medical Genetics, University of Lausanne, Lausanne, 1011, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland.; Centre Hospitalier Universitaire (CHUV), University Institute for Social and Preventive Medicine, Lausanne, 1010, Switzerland., Koller DL; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Kutalik Z; Department of Medical Genetics, University of Lausanne, Lausanne, 1011, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland.; Centre Hospitalier Universitaire (CHUV), University Institute for Social and Preventive Medicine, Lausanne, 1010, Switzerland., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK., Malkin I; Sackler Faculty of Medicine, Department of Anatomy and Anthropology, Tel Aviv University, Tel Aviv, 6997801, Israel., Ried JS; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Smith AV; Icelandic Heart Association, Kopavogur, 201, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Thorleifsson G; deCODE Genetics, Reykjavik, 101, Iceland., Vandenput L; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Hua Zhao J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK., Zhang W; Department Epidemiology and Biostatistics, School of Public Health, Imperial College, London, SW7 2AZ, UK.; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK., Aghdassi A; Department of Medicine A, University of Greifswald, Greifswald, 17489, Germany., Åkesson K; Department of Clinical Sciences, Lund University, Malmö, 22362, Sweden.; Department of Orthopedics, Skåne University Hospital, Malmö, S-205 02, Sweden., Amin N; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Baier LJ; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ, 85014, USA., Barroso I; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK.; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, CB2 OQQ, UK.; Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge Metabolic Research Laboratories, Cambridge, CB2 OQQ, UK., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA., Bertram L; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Experimental & Integrative Genomics, University of Lübeck, Lübeck, 23562, Germany.; School of Public Health, Faculty of Medicine, Imperial College London, London, W6 8RP, UK., Biffar R; Centre of Oral Health, Department of Prosthetic Dentistry, Gerodontology and Biomaterials, University of Greifswald, Greifswald, 17489, Germany., Bochud M; Centre Hospitalier Universitaire (CHUV), University Institute for Social and Preventive Medicine, Lausanne, 1010, Switzerland., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, MO, 63110, USA.; Division of Biostatistics, Washington University School of Medicine, St Louis, MO, 63110, USA., Buchman AS; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA., Byberg L; Department of Surgical Sciences, Uppsala University, Uppsala, 75185, Sweden., Campbell H; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, EH8 9AG, UK., Campos Obanda N; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands., Cauley JA; Department of Epidemiology Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Cawthon PM; California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA., Cederberg H; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Chen Z; Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, 85714, USA., Cho NH; Department of Preventive Medicine, Ajou University School of Medicine, Youngtong-Gu, Suwon, 16499, Korea., Jin Choi H; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea.; Department of Internal Medicine, Chungbuk National University Hospital, Cheongju Si, Korea., Claussnitzer M; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute, Cambridge, MA, 02142, USA.; Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, 02139, USA.; Institute of Human Genetics, MRI, Technische Universität München, Munich, 81675, Germany.; Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA., Collins F; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, Bethesda, MD, 20892, USA., Cummings SR; California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA., De Jager PL; Harvard Medical School, Boston, MA, 02115, USA.; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, 02142, USA., Demuth I; Lipid Clinic at the Interdisciplinary Metabolism Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, 13353, Germany.; Institute of Medical and Human Genetics, Charité - Universitätsmedizin Berlin, Berlin, 13353, Germany., Dhonukshe-Rutten RAM; Department of Human Nutrition, Wageningen University, PO Box 17, Wageningen, 6700 AA, The Netherlands., Diatchenko L; Alan Edwards Centre for Research on Pain, McGill University, Montreal, H3A 0G1, Canada.; Regional Center for Neurosensory Disorders, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Eiriksdottir G; Icelandic Heart Association, Kopavogur, 201, Iceland., Enneman AW; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands., Erdos M; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, Bethesda, MD, 20892, USA., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, 00014, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, 00014, Finland.; Folkhalsan Research Centre, Helsinki, 00250, Finland.; Vasa Central Hospital, Vasa, 65130, Finland.; National Institute for Health and Welfare, Helsinki, 00271, Finland., Eriksson J; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Estrada K; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Evans DS; California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, MO, 63110, USA., Fu M; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Garcia M; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute for Aging, Bethesda, MD, 20892, USA., Gieger C; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Girke T; Institute for Integrative Genome Biology, University of California, Riverside, CA, 92521, USA.; Department of Botany and Plant Sciences, University of California, Riverside, CA, 92521, USA., Glazer NL; Departments of Medicine and Epidemiology, Boston University School of Medicine and Public Health, Boston, MA, 02118, USA., Grallert H; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Department of Botany and Plant Sciences, University of California, Riverside, CA, 92521, USA.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; CCG Type 2 Diabetes, Helmholtz Zentrum München, Neuherberg, 85764, Germany.; CCG Nutrigenomics and Type 2 Diabetes. Helmholtz Zentrum München, Neuherberg, 85764, Germany., Grewal J; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Han BG; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, 28159, Korea., Hanson RL; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ, 85014, USA., Hayward C; MRC Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh, Scotland, EH4 2XU, UK., Hofman A; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Hoffman EP; Department of Pharmaceutical Sciences, SUNY Binghamton, Binghamton, NY, 13902, USA., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, 17487, Germany., Hsueh WC; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ, 85014, USA., Hubal MJ; Department of Exercise and Nutrition Sciences, George Washington University, Washington, DC, 20052, USA.; Research Center for Genetic Medicine, Children's National Medical Center, Washington, DC, 20052, USA., Hubbard A; Division of Biostatistics, School of Public Health, University of California, Berkeley, CA, 94720, USA., Huffman KM; Division of Rheumatology, Department of Medicine, Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Husted LB; Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, DK 8000, Denmark., Illig T; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Department of Human Genetics, Hannover Medical School, Hannover, 30625, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, 30625, Germany., Ingelsson E; Department of Medical Sciences, Uppsala University, Uppsala, 75185, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA., Ittermann T; Institute for Community Medicine, University of Greifswald, Greifswald, 17489, Germany., Jansson JO; Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE 405 30, Sweden., Jordan JM; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27517, USA., Jula A; National Institute for Health and Welfare, Helsinki, 00271, Finland., Karlsson M; Department of Clinical Sciences and Orthopaedics, Lund University, Skåne University Hospital SUS, Malmö, 22362, Sweden., Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Kilpeläinen TO; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK.; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Copenhagen, 2100, Denmark.; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Klopp N; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, 30625, Germany., Kloth JSL; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands., Koistinen HA; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, 00029, Finland.; Endocrinology, Abdominal Center, University of Helsinki and Helsinki University Central Hospital, Helsinki, 00029, Finland.; Department of Health, National Institute for Health and Welfare, Helsinki, 00271, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, 00290, Finland., Kraus WE; Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Kritchevsky S; Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Kuulasmaa T; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Lahti J; Institute of Behavioural Sciences, University of Helsinki, Helsinki, FI00014, Finland., Lang T; University of California San Francisco, San Francisco, CA, 94143, USA., Langdahl BL; Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, DK 8000, Denmark., Launer LJ; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute for Aging, Bethesda, MD, 20892, USA., Lee JY; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, 28159, Korea., Lerch MM; Department of Medicine A, University of Greifswald, Greifswald, 17489, Germany., Lewis JR; School of Medicine and Pharmacology, University of Western Australia, Perth, 6009, Australia.; Centre for Kidney Research, School of Public Health, University of Sydney, Sydney, 2006, Australia., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, 75185, Sweden., Lindgren C; Wellcome Trust Centre for Human Genetics, Oxford University, Oxford, OX3 7BN, UK., Liu Y; Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, 27517, USA., Liu T; Max Planck Institute for Molecular Genetics, Berlin, 14195, Germany.; Max Planck Institute for Human Development, Berlin, 14195, Germany., Liu Y; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27517, USA., Ljunggren Ö; Department of Medical Sciences, Uppsala University, Uppsala, 75185, Sweden., Lorentzon M; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Luben RN; Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Maixner W; Regional Center for Neurosensory Disorders, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., McGuigan FE; Department of Clinical Sciences, Lund University, Malmö, 22362, Sweden., Medina-Gomez C; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Meitinger T; Institute of Human Genetics, MRI, Technische Universität München, Munich, 81675, Germany.; Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Melhus H; Department of Medical Sciences, Uppsala University, Uppsala, 75185, Sweden., Mellström D; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Melov S; Buck Institute for Research on Aging, Novato, CA, 94945, USA.; Leonard Davis School of Gerontology, University of Southern California, LA, CA, 90089, USA., Michaëlsson K; Department of Surgical Sciences, Uppsala University, Uppsala, 75185, Sweden., Mitchell BD; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, 21201, USA., Morris AP; Wellcome Trust Centre for Human Genetics, Oxford University, Oxford, OX3 7BN, UK.; Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3BX, UK., Mosekilde L; Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, DK 8000, Denmark., Newman A; Center for Aging and Population Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Nielson CM; Oregon Health & Science University, Portland, OR, 97239, USA., O'Connell JR; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Oostra BA; Department of Clinical Genetics, Erasmus MC, Rotterdam, 300 CA, The Netherlands.; Centre for Medical Systems Biology and Netherlands Consortium on Healthy Aging, Leiden, RC2300, The Netherlands., Orwoll ES; Oregon Health & Science University, Portland, OR, 97239, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland.; Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, FI00014, Finland., Parker SCJ; Human Genetics and Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA., Peacock M; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Perola M; National Institute for Health and Welfare, Helsinki, 00271, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland.; Diabetes and Obesity Research Program, University of Helsinki, Helsinki, FI00014, Finland.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Polasek O; Faculty of Medicine, Department of Public Health, University of Split, Split, 21000, Croatia., Prince RL; School of Medicine and Pharmacology, University of Western Australia, Perth, 6009, Australia.; Department of Endocrinology and Diabetes, Sir Charles Gardiner Hospital, Perth, 6009, Australia., Räikkönen K; Institute of Behavioural Sciences, University of Helsinki, Helsinki, FI00014, Finland., Ralston SH; Molecular Medicine Centre, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, EH4 2XU, UK., Ripatti S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland.; Hjelt Institute, University of Helsinki, Helsinki, Finland.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK., Robbins JA; Department of Medicine, University of California at Davis, Sacramento, CA, 95817, USA., Rotter JI; Institute for Translational Genomic and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor UCLA Medical Center, Torrance, CA, 90502, USA., Rudan I; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, EH8 9AG, UK., Salomaa V; National Institute for Health and Welfare, Helsinki, 00271, Finland., Satterfield S; Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, 38163, USA., Schadt EE; Department of Genetics and Genomic Science, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Schipf S; Institute for Community Medicine, University of Greifswald, Greifswald, 17489, Germany., Scott L; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Sehmi J; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Shen J; Oregon Health & Science University, Portland, OR, 97239, USA., Soo Shin C; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea., Sigurdsson G; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; Department of Endocrinology and Metabolism, Landspitali, The National University Hospital of Iceland, Reykjavik, 101, Iceland., Smith S; Center for Translational Pain Medicine, Department of Anesthiology, Duke University Medical Center, Durham, NC, 27110, USA., Soranzo N; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK., Stančáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Steinhagen-Thiessen E; Lipid Clinic at the Interdisciplinary Metabolism Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, 13353, Germany., Streeten EA; Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Geriatric Research and Education Clinical Center (GRECC) - Veterans Administration Medical Center, Baltimore, MD, 21201, USA., Styrkarsdottir U; deCODE Genetics, Reykjavik, 101, Iceland., Swart KMA; Department of Epidemiology and Biostatistics, and the EMGO Institute, VU University Medical Center, Amsterdam, BT1081, The Netherlands., Tan ST; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Tarnopolsky MA; Department of Medicine, McMaster University Medical Center, Hamilton, ON, Canada, L8N 3Z5., Thompson P; Department of Pathology, Stony Brook School of Medicine, Stony Brook, NY, 11794, USA., Thomson CA; Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, 85714, USA., Thorsteinsdottir U; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; deCODE Genetics, Reykjavik, 101, Iceland., Tikkanen E; National Institute for Health and Welfare, Helsinki, 00271, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland.; Molecular Medicine Centre, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, EH4 2XU, UK., Tranah GJ; California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA., Tuomilehto J; Vasa Central Hospital, Vasa, 65130, Finland.; Department of Neuroscience and Preventive Medicine, Danube-University Krems, Krems, 3500, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah, 12589, Saudi Arabia.; Dasman Diabetes Institute, Dasman, 15462, Kuwait., van Schoor NM; Department of Epidemiology and Biostatistics, and the EMGO Institute, VU University Medical Center, Amsterdam, BT1081, The Netherlands., Verma A; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK., Vollenweider P; Department of Medicine and Internal Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, CH-1011, Switzerland., Völzke H; Institute for Community Medicine, University of Greifswald, Greifswald, 17489, Germany., Wactawski-Wende J; Department of Epidemiology and Environmental Health, University at Buffalo, State University of New York, Buffalo, NY, 14214, USA., Walker M; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Weedon MN; Genetics of Complex Traits, University of Exeter Medical School, Exeter, EX1 2LU, UK., Welch R; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Wichmann HE; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich, 81377, Germany.; Institute of Medical Statistics and Epidemiology, Technical University, Munich, 81675, Germany., Widen E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00251, Finland., Williams FMK; Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Campus, London, WC2R 2LS, UK., Wilson JF; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, EH8 9AG, UK.; MRC Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh, Scotland, EH4 2XU, UK., Wright NC; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Xie W; Genetics of Complex Traits, University of Exeter Medical School, Exeter, EX1 2LU, UK., Yu L; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA., Zhou Y; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Chambers JC; Department Epidemiology and Biostatistics, School of Public Health, Imperial College, London, SW7 2AZ, UK.; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; NIHR Cardiovascular Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, SW3 6NP, UK.; Imperial College Healthcare NHS Trust, London, W2 1NY, UK., Döring A; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., van Duijn CM; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands.; Centre for Medical Systems Biology and Netherlands Consortium on Healthy Aging, Leiden, RC2300, The Netherlands., Econs MJ; Department of Medicine and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Gudnason V; Icelandic Heart Association, Kopavogur, 201, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Kooner JS; Cardiology Department, Ealing Hospital NHS Trust, Middlesex, UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK.; Imperial College Healthcare NHS Trust, London, W2 1NY, UK., Psaty BM; Departments of Medicine, Epidemiology, and Health Services, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, 98101, USA.; Kaiser Permanente Washington Health Research Institute, Washington, Seattle, WA, 98101, USA., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Campus, London, WC2R 2LS, UK., Stefansson K; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; deCODE Genetics, Reykjavik, 101, Iceland., Rivadeneira F; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Uitterlinden AG; Department of Internal Medicine, Erasmus MC, Rotterdam, 3000, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, 2593, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, 3000, The Netherlands., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK., Ossowski V; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ, 85014, USA., Waterworth D; Medical Genetics, GlaxoSmithKline, Philadelphia, PA, 19112, USA., Loos RJF; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OQQ, UK.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Institute of Child Health and Development, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; The Genetics of Obesity and Related Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Karasik D; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, 1311502, Israel., Harris TB; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute for Aging, Bethesda, MD, 20892, USA., Ohlsson C; Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-405 30, Sweden., Kiel DP; Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA. kiel@hsl.harvard.edu.; Harvard Medical School, Boston, MA, 02115, USA. kiel@hsl.harvard.edu.; Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA. kiel@hsl.harvard.edu.
Publikováno v:
Nature communications [Nat Commun] 2017 Jul 19; Vol. 8 (1), pp. 80. Date of Electronic Publication: 2017 Jul 19.
Autor:
Ried JS; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Jeff M J; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Chu AY; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA., Bragg-Gresham JL; Kidney Epidemiology and Cost Center, Internal Medicine-Nephrology, University of Michigan, Ann Arbor, Michigan 48109, USA., van Dongen J; Department of Biological Psychology, VU University, 1081BT Amsterdam, The Netherlands., Huffman JE; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, EH4 2XU Edinburgh, Scotland., Ahluwalia TS; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark.; Steno Diabetes Center A/S, DK-2820 Gentofte, Denmark.; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Ledreborg Allé 34, DK-2820 Copenhagen, Denmark., Cadby G; Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Western Australia 6009, Australia., Eklund N; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Eriksson J; Department of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden., Esko T; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 2142, USA.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Goel A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Gorski M; Department of Nephrology, University Hospital Regensburg, 93042 Regensburg, Germany.; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, 93053 Regensburg, Germany., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, EH4 2XU Edinburgh, Scotland., Heard-Costa NL; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA., Jackson AU; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Jokinen E; Hospital for Children and Adolescents, University of Helsinki, FI-00290 Helsinki, Finland., Kanoni S; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Kristiansson K; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland.; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland., Kutalik Z; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; Department of Medical Genetics, University of Lausanne, Lausanne, 1005, Switzerland.; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), 1010 Lausanne, Switzerland., Lahti J; Folkhälsan Research Centre, FI-00290 Helsinki, Finland.; Institute of Behavioural Sciences, University of Helsinki, FI-00014 Helsinki, Finland., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Mägi R; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Medina-Gomez C; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Monda KL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.; The Center for Observational Research, Amgen Inc., Thousand Oaks, California 91320-1799, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands., Pérusse L; Department of Kinesiology, Laval University, Québec, Québec, Canada G1V 0A6.; Institute of Nutrition and Functional Foods, Laval University, Québec, Québec, Canada G1V 0A6., Prokopenko I; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK., Qi L; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA., Salvi E; Department of Health Sciences, University of Milano at San Paolo Hospital, 20139 Milano, Italy.; Filarete Foundation, Genomic and Bioinformatics Unit, Milano 20139, Italy., Smith MT; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands., Stančáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Ju Sung Y; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Tachmazidou I; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK., Teumer A; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany., Thorleifsson G; deCODE Genetics, Amgen inc., 101 Reykjavik, Iceland., van der Harst P; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, 3501 DG Utrecht, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.; Department of Cardiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, Netherlands., Walker RW; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Wang SR; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Divisions of Genetics and Endocrinology and Program in Genomics, Boston's Children's Hospital, Boston, Massachusetts 02115, USA., Wild SH; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, EH8 9AG Teviot Place, Edinburgh, Scotland., Willems SM; Department of Epidemiology, Genetic Epidemiology Unit, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands., Wong A; MRC Unit for Lifelong Health &Ageing at UCL, London WC1B 5JU, UK., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Albrecht E; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Couto Alves A; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London W12 0NN, UK., Bakker SJ; Department of Medicine, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, Netherlands., Barlassina C; Department of Health Sciences, University of Milano at San Paolo Hospital, 20139 Milano, Italy.; Filarete Foundation, Genomic and Bioinformatics Unit, Milano 20139, Italy., Bartz TM; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.; Department of Medicine, University of Washington, Seattle, Washington 98101, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA., Beilby J; Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia 6009, Australia., Bellis C; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4001, Australia.; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research of Singapore, Singapore 138672, Singapore., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA., Bergmann S; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; Department of Medical Genetics, University of Lausanne, Lausanne, 1005, Switzerland., Blangero J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520, USA., Blüher M; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.; Department of Medicine, University of Leipzig, 04103 Leipzig, Germany., Boerwinkle E; Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas 77030, USA., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Bornstein SR; Medical Faculty Carl Gustav Carus, Department of Medicine III, University of Dresden, 01307 Dresden, Germany., Bruinenberg M; University of Groningen, University Medical Center Groningen, The LifeLines Cohort Study, 9700 RB Groningen, The Netherlands., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, EH8 9AG Teviot Place, Edinburgh, Scotland., Chen YI; Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Chiang CW; Department of Psychiatry, University of California, Los Angeles, California 90095, USA., Chines PS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Cucca F; University of Sassari, 07100 Sassari, Italy., Cupples LA; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA., D'Avila F; Department of Health Sciences, University of Milano at San Paolo Hospital, 20139 Milano, Italy.; Filarete Foundation, Genomic and Bioinformatics Unit, Milano 20139, Italy., de Geus EJ; Department of Biological Psychology, VU University, 1081BT Amsterdam, The Netherlands.; EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece., Dimitriou M; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece., Döring A; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Eriksson JG; Folkhälsan Research Centre, FI-00290 Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki, Finland., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece., Farrall M; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Fischer K; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Forouhi NG; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany., Gjesing AP; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark., Glorioso N; Hypertension and Related Disease Centre, AOU-University of Sassari, 7100 Sassari, Italy., Graff M; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA., Grallert H; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Grarup N; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark., Gräßler J; Department of Medicine III, Pathobiochemistry, Technische Universitaet, 01307 Dresden, Germany., Grewal J; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Hamsten A; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Medicine Solna, Atherosclerosis Research Unit, Karolinska Institutet, 17176 Stockholm 17176, Sweden.; Center for Molecular Medicine, Karolinska University Hospital, 17176 Stockholm, Sweden., Harder MN; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark., Hartman CA; University of Groningen, University Medical Center Groningen, Interdisciplinary Center Psychopathology and Emotion Regulation, 9700 RB Groningen, The Netherlands., Hassinen M; Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland., Hastie N; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, EH4 2XU Edinburgh, Scotland., Hattersley AT; Institue of Biomedical &Clinical Science, University of Exeter, Barrack Road, Exeter EX2 5DW, UK., Havulinna AS; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Heliövaara M; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Hillege H; Department of Cardiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, Netherlands., Hofman A; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Holmen O; Department of Public Health and General Practice, Norwegian University of Science and Technology, 7489 Trondheim, Norway., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany., Hottenga JJ; Department of Biological Psychology, VU University, 1081BT Amsterdam, The Netherlands., Hui J; Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia 6009, Australia.; School of Population Health, University of Western Australia, Nedlands, Western Australia 6009, Australia., Husemoen LL; Research Centre for Prevention and Health, Glostrup Hospital, 2600 Glostrup, Denmark., Hysi PG; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Isaacs A; Department of Epidemiology, Genetic Epidemiology Unit, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands., Ittermann T; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany., Jalilzadeh S; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., James AL; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia., Jørgensen T; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Faculty of Medicine, University of Aalborg, 9220 Aalborg, Denmark.; Research Centre for Prevention and Health, Capital Region of Denmark, DK2600 Glostrup, Denmark., Jousilahti P; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Jula A; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Marie Justesen J; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark., Justice AE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, FI-33521 Tampere, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, FI-33014 Tampere, Finland., Karaleftheri M; Echinos Medical Centre, 67300 Echinos, Greece., Tee Khaw K; Clinical Gerontology Unit, Box 251, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK., Keinanen-Kiukaanniemi SM; Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu F1-90014, Finland.; Unit of General Practice, Oulu University Hospital, Oulu FI-90029, Finland., Kinnunen L; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Knekt PB; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Koistinen HA; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Department of Medicine and Abdominal Center: Endocrinology, University of Helsinki and Helsinki University Central Hospital,, 00029 Helsinki, Finland.; Minerva Foundation Institute for Medical Research, 00290 Helsinki, Finland., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, 21000 Split, Croatia., Kooner IK; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Koskinen S; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Kovacs P; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany., Kyriakou T; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Laitinen T; Kuopio University Hospital, 70029 Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, University of Eastern Finland, FI-70211 Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.; Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK., Lewin AM; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London W12 0NN, UK., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Lindgren CM; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 2142, USA.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; The Big Data Institute, University of Oxford, Oxford OX3 7LJ, UK., Lindström J; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Linneberg A; Research Centre for Prevention and Health, Glostrup Hospital, 2600 Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, 2600 Glostrup, Denmark., Lorbeer R; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany., Lorentzon M; Department of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden., Luben R; Strangeways Research Laboratory Wort's Causeway, Cambridge CB1 8RN, UK., Lyssenko V; Steno Diabetes Center A/S, DK-2820 Gentofte, Denmark.; Lund University Diabetes Centre and Department of Clinical Science, Diabetes &Endocrinology Unit, Lund University, 221 00 Malmö, Sweden., Männistö S; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Manunta P; Chair of Nephrology, Università Vita Salute San Raffaele and Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan 20139, Italy., Leach IM; Department of Cardiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, Netherlands., McArdle WL; School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UK., Mcknight B; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA.; Divison of Public Health Sciences, Program in Biostatistics and Biomathematics, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Mihailov E; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Mills R; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Montasser ME; Division of Endocrinology, Diabetes &Nutrition, Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK., Müller G; Center for Evidence Based Healthcare, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, 01307, Germany., Musk AW; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, West Australia 6009, Australia., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Ong KK; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.; MRC Unit for Lifelong Health &Ageing at UCL, London WC1B 5JU, UK.; Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK., Oostra BA; Department of Epidemiology, Genetic Epidemiology Unit, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands., Osmond C; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK., Palotie A; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts 02114, USA., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455-0381, USA., Paternoster L; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS8 1TH, UK., Penninx BW; Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, AJ Ernstraat 1887, 1081 HL Amsterdam, The Netherlands., Pichler I; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), 39100 Bolzano, Italy.; Affiliated Institute of the University of Lübeck, 23562 Lübeck, Germany., Pilia MG; Istituto di Ricerca Genetica e Biomedica, CNR, 9042 Monserrato, Italy., Polašek O; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, EH8 9AG Teviot Place, Edinburgh, Scotland.; Department of Public Health, Faculty of Medicine, University of Split, 21000 Split, Croatia., Pramstaller PP; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), 39100 Bolzano, Italy.; Affiliated Institute of the University of Lübeck, 23562 Lübeck, Germany.; Department of Neurology, University of Lübeck, 23562 Lübeck, Germany.; Department of Neurology, General Central Hospital, 39100 Bolzano, Italy., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FI-20520 Turku, Finland., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Rayner NW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton CB10 1HH, UK., Ribel-Madsen R; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark., Rice TK; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Richards M; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.; MRC Unit for Lifelong Health &Ageing at UCL, London WC1B 5JU, UK., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.; Harvard Medical School, Boston, Massachusetts, 02115, USA., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Ryan KA; Division of Endocrinology, Diabetes &Nutrition, Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA., Sanna S; Istituto di Ricerca Genetica e Biomedica, CNR, 9042 Monserrato, Italy., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA., Scholtens S; Department of Epidemiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Sebert S; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK.; Biocenter Oulu, University of Oulu, Oulu FI-90014, Finland.; Center For Life-Course Health Research, University of Oulu, FI-90014 Oulu, Finland., Southam L; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK., Sparsø TH; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark., Steinthorsdottir V; deCODE Genetics, Amgen inc., 101 Reykjavik, Iceland., Stirrups K; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Stolk RP; Department of Epidemiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Stringham HM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Swertz MA; Department of Genetics, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Tönjes A; Department of Medicine, University of Leipzig, 04103 Leipzig, Germany., Tsafantakis E; Anogia Medical Centre, 74051 Anogia, Greece., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands., Van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands., Vandenput L; Department of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden., Vartiainen E; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Venturini C; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; Institute of Ophthalmology, University College London, London EC1V 9EL, UK., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, Netherlands., Viikari JS; Department of Medicine, University of Turku, FI-20521 Turku, Finland.; Division of Medicine, Turku University Hospital, Turku, Finland., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, EH4 2XU Edinburgh, Scotland., Vohl MC; Institute of Nutrition and Functional Foods, Laval University, Québec, Québec, Canada G1V 0A6.; School of Nutrition, Laval University, Québec, Québec, Canada G1V 0A6., Vonk JM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands., Waeber G; Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland., Widén E; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland., Willemsen G; Department of Biological Psychology, VU University, 1081BT Amsterdam, The Netherlands., Wilsgaard T; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, 9037 Tromsø, Norway., Winkler TW; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, 93053 Regensburg, Germany., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, EH4 2XU Edinburgh, Scotland., Yerges-Armstrong LM; Division of Endocrinology, Diabetes &Nutrition, Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA., Hua Zhao J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Zillikens MC; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Boomsma DI; Department of Biological Psychology, VU University, 1081BT Amsterdam, The Netherlands., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.; Imperial College Healthcare NHS Trust, London W12 0HS, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.; Harvard Medical School, Boston, Massachusetts, 02115, USA., Cusi D; Department of Health Sciences, University of Milano at San Paolo Hospital, 20139 Milano, Italy.; Filarete Foundation, Genomic and Bioinformatics Unit, Milano 20139, Italy., Gansevoort RT; Department of Medicine, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, Netherlands., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Hansen T; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, 5000 Odense, Denmark., Hicks AA; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), 39100 Bolzano, Italy.; Affiliated Institute of the University of Lübeck, 23562 Lübeck, Germany., Hu F; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Hveem K; Department of Public Health and General Practice, Norwegian University of Science and Technology, 7489 Trondheim, Norway., Jarvelin MR; Biocenter Oulu, University of Oulu, Oulu FI-90014, Finland.; Unit of Primary Care, Oulu University Hospital, 90029 OYS Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment &Health, School of Public Health, Imperial College London W12 0NN, UK.; Faculty of Medicine, Center for Life Course Epidemiology, University of Oulu, P.O.Box 5000, FI-90014 Oulu, Finland., Kajantie E; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Children's Hospital, Helsinki University Hospital and University of Helsinki, FI-00029 Helsinki, Finland.; Department of Obstetrics and Gynecology, MRC Oulu, Oulu University Hospital and University of Oulu, FI-90029 Oulu, Finland., Kooner JS; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.; Imperial College Healthcare NHS Trust, London W12 0HS, UK.; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Kuh D; MRC Unit for Lifelong Health &Ageing at UCL, London WC1B 5JU, UK., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Lakka TA; Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, 70210 Kuopio, Finland., Lehtimäki T; Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, FI-33520 Tampere, Finland., Metspalu A; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Njølstad I; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, 9037 Tromsø, Norway.; Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, 9037 Tromsø, Norway., Ohlsson C; Department of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden., Oldehinkel AJ; University of Groningen, University Medical Center Groningen, Interdisciplinary Center Psychopathology and Emotion Regulation, 9700 RB Groningen, The Netherlands., Palmer LJ; School of Public Health, University of Adelaide, Adelaide, South Australia 5005, Australia.; Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia., Pedersen O; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark., Perola M; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland.; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, 80802 Munich, Germany., Psaty BM; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA.; Department of Medicine, University of Washington, Seattle, Washington 98101, USA.; Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington 98101, USA.; Group Health Research Institute, Group Health Cooperative, Seatte, Washington 98101, USA., Puolijoki H; South Ostrobothnia Central Hospital, Seinäjoki Fi-60220, Finland., Rauramaa R; Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, 70211 Kuopio, Finland., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, EH8 9AG Teviot Place, Edinburgh, Scotland., Salomaa V; Department of Health, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland., Schwarz PE; Medical Faculty Carl Gustav Carus, Department of Medicine III, University of Dresden, 01307 Dresden, Germany.; Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), Dresden 01307, Germany., Shudiner AR; Division of Endocrinology, Diabetes &Nutrition, Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland 21042, USA., Smit JH; Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, AJ Ernstraat 1887, 1081 HL Amsterdam, The Netherlands., Sørensen TI; Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, 2100 Copenhagen, Denmark.; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UK.; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, 2000 Frederiksberg, Denmark., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Stefansson K; deCODE Genetics, Amgen inc., 101 Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland., Stumvoll M; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.; Department of Medicine, University of Leipzig, 04103 Leipzig, Germany., Tremblay A; Department of Kinesiology, Laval University, Québec, Québec, Canada G1V 0A6., Tuomilehto J; Diabetes Prevention Unit, National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, 70211 Kuopio, Finland.; Research Unit, Kuopio University Hospital, 70029 Kuopio, Finland., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, 17475 Greifswald, Germany., Vollenweider P; Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, EH4 2XU Edinburgh, Scotland.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, EH8 9AG Teviot Place, Edinburgh, Scotland., Zeggini E; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK., Abecasis GR; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Boehnke M; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton CB10 1HH, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 21589, Saudi Arabia., van Duijn CM; Department of Epidemiology, Genetic Epidemiology Unit, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.; Center for Medical Systems Biology, 2300 Leiden, The Netherlands., Fox C; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.; Harvard Medical School, Boston, Massachusetts, 02115, USA., Groop LC; Lund University Diabetes Centre and Department of Clinical Science, Diabetes &Endocrinology Unit, Lund University, 221 00 Malmö, Sweden.; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, 00014 Helsinki, Finland., Heid IM; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, 93053 Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany., Hunter DJ; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 2142, USA.; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Kaplan RC; Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford OX3 7LJ, UK., North KE; Department of Epidemiology, Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7400, USA., O'Connell JR; Division of Endocrinology, Diabetes &Nutrition, Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA., Schlessinger D; National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA., Thorsteinsdottir U; deCODE Genetics, Amgen inc., 101 Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland., Strachan DP; Population Health Research Institute, St George's, University of London, London SW17 0RE, UK., Frayling T; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Hirschhorn JN; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 2142, USA.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Divisions of Genetics and Endocrinology and Program in Genomics, Boston's Children's Hospital, Boston, Massachusetts 02115, USA.; Metabolism Initiative, Broad Institute, Cambridge, Massachusetts 02142, USA., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, 81377 Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, 80802 Munich, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Loos RJ; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Publikováno v:
Nature communications [Nat Commun] 2016 Nov 23; Vol. 7, pp. 13357. Date of Electronic Publication: 2016 Nov 23.
Autor:
Lu Y; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Day FR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Gustafsson S; Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, 751 85 Uppsala, Sweden., Buchkovich ML; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Na J; Department of Developmental and Regenerative Biology, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Bataille V; West Herts NHS Trust, Herts HP2 4AD, UK.; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Cousminer DL; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland., Dastani Z; Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2., Drong AW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Esko T; Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA., Evans DM; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland 4102, Australia.; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited., Falchi M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Hedman ÅK; Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, 751 85 Uppsala, Sweden.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Haring R; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; European University of Applied Sciences, Faculty of Applied Public Health, 18055 Rostock, Germany., Hysi PG; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Iles MM; Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK., Justice AE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK., Lagou V; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK., Li R; Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2., Li X; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Locke A; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA., Lu C; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Mägi R; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia., Perry JR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Pers TH; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge 02142, USA.; Department of Epidemiology Research, Statens Serum Institut, 2100 Copenhagen, Denmark., Qi Q; Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA., Sanna M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK., Schmidt EM; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Shungin D; Lund University Diabetes Centre, Department of Clinical Science, Genetic and Molecular Epidemiology Unit, Skåne University Hosptial, 205 02 Malmö, Sweden.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, 901 87 Umeå, Sweden.; Department of Odontology, Umeå University, 901 85 Umeå, Sweden., Teumer A; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany., Vinkhuyzen AA; Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia., Walker RW; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Westra HJ; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02446, USA.; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts 02446, USA., Zhang M; Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Zhu Z; Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia., Afzal U; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Ahluwalia TS; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health and Medical Sceinces, University of Copenhagen, 2200 Copenhagen, Denmark.; Danish Pediatric Asthma Center, Gentofte Hospital, The Capital Region, 2200 Copenhagen, Denmark.; Steno Diabetes Center A/S, DK-2820 Gentofte, Denmark., Bakker SJ; University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands., Bellis C; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA., Bonnefond A; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Borodulin K; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Buchman AS; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA., Cederholm T; Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 751 85 Uppsala, Sweden., Choh AC; Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA., Choi HJ; Department of Anatomy, Seoul National University College of Medicine, Seoul 03080, Korea., Curran JE; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520., de Groot LC; Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands., De Jager PL; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.; Harvard Medical School, Boston, Massachusetts 02115, USA.; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA., Dhonukshe-Rutten RA; Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands., Enneman AW; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Eury E; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Evans DS; California Pacific Medical Center Research Institute, San Francisco, California 94107, USA., Forsen T; Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki, Finland., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany., Fumeron F; INSERM, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.; Université Paris Descartes, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.; Univ Paris Diderot, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France., Garcia ME; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA., Gärtner S; Department of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany., Han BG; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea., Havulinna AS; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA., Hillege H; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands., Ittermann T; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany., Kent JW; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia., Laatikainen T; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Hospital District of North Karelia, FI-80210 Joensuu, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, FI-70211 Kuopio, Finland., Lahti J; Folkhälsan Research Centre, FI-00290 Helsinki, Finland.; Institute of Behavioural Sciences, University of Helsinki, FI-00014 Helsinki, Finland., Mateo Leach I; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands., Lee CG; Department of Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA.; Research Service, Veterans Affairs Medical Center, Portland, Oregon 97239, USA., Lee JY; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea., Liu T; Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, 14195 Berlin, Germany.; Max Planck Institute for Human Development, 14194 Berlin, Germany., Liu Y; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA., Lobbens S; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore 138648, Singapore., Lyytikäinen LP; Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, FI-33520 Tampere, Finland., Medina-Gomez C; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Michaëlsson K; Department of Surgical Sciences, Orthopedics, Uppsala University, 751 85 Uppsala, Sweden., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA., Nielson CM; School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.; Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA., Oozageer L; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Pascoe L; Institute of Cell &Molecular Biosciences, Newcastle University, Newcastle NE1 7RU, UK., Paternoster L; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited., Polašek O; Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK., Ripatti S; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.; Hjelt Institute, University of Helsinki, FI-00014 Helsinki, Finland., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA., Shin CS; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea., Narančić NS; Institute for Anthropological Research, Zagreb 10000, Croatia., Spira D; The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.; Lipid Clinic at the Interdisciplinary Metabolism Center, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany., Srikanth P; School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.; Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA., Steinhagen-Thiessen E; The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.; Lipid Clinic at the Interdisciplinary Metabolism Center, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA., Swart KM; EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.; VUMC, Department of Epidemiology and Biostatistics, 1081 BT Amsterdam, The Netherlands., Taittonen L; Department of Pediatrics, University of Oulu, FI-90014 Oulu, Finland.; Department of Pediatrics, Vaasa Central Hospital, FI-65100 Vaasa, Finland., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA., Tikkanen E; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; Hjelt Institute, University of Helsinki, FI-00014 Helsinki, Finland., van der Velde N; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., van Schoor NM; EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.; VUMC, Department of Epidemiology and Biostatistics, 1081 BT Amsterdam, The Netherlands., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Yu L; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA., Zmuda JM; Department of Epidemiology; University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA., Eklund N; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Jackson AU; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA., Kristiansson K; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kuulasmaa T; Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland., Kuusisto J; Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Department of Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Kuopio University Hospital, 70029 Kuopio, Finland., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Männistö S; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Palmer CD; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA., Ried JS; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Stancáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Wagner PJ; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Demirkan A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands., Döring A; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Gudnason V; Icelandic Heart Association, Kopavogur 201, Iceland.; University of Iceland, Faculty of Medicine, Reykjavik 101, Iceland., Kiel DP; Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115.; Institute for Aging Research Hebrew Senior Life, Boston, Massachusetts 02131, USA., Kühnel B; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Mcknight B; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA.; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., O'Connell JR; Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands., Shuldiner AR; Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland 21042, USA., Song K; Genetics, Projects Clinical Platforms and Sciences, GlaxoSmithKline, Philadelphia, Pennsylvania 19112, USA., Vandenput L; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden., van Duijn CM; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.; Center for Medical Systems Biology, 2300 Leiden, The Netherlands., Vollenweider P; Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland., White CC; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA., Boettcher Y; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.; University of Leipzig, Department of Medicine, 04103 Leipzig, Germany., Cooper RS; Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA., Forouhi NG; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Grallert H; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany., Hingorani A; Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK., Jørgensen T; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Faculty of Medicine, University of Aalborg, 9220 Aalborg, Denmark.; Research Centre for Prevention and Health, DK2600 Capital Region of Denmark, Denmark., Jousilahti P; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kivimaki M; Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK., Kumari M; Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK., Laakso M; Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Department of Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Kuopio University Hospital, 70029 Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.; Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK., Linneberg A; Research Centre for Prevention and Health, Glostrup Hospital, 2600 Glostrup, Denmark., Luke A; Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA., Mckenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica., Palotie A; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts 02114, USA., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Tayo BO; Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA., Bertram L; School of Public Health, Faculty of Medicine, Imperial College London, London W6 8RP, UK.; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Integrative and Experimental Genomics, University of Lübeck, 23562 Lübeck, Germany., Blangero J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520., Blüher M; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.; University of Leipzig, Department of Medicine, 04103 Leipzig, Germany., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK., Cho NH; Ajou University School of Medicine, Department of Preventive Medicine, Suwon Kyoung-gi 443-721, Korea., Cummings SR; California Pacific Medical Center Research Institute, San Francisco, California 94107, USA., Czerwinski SA; Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA., Demuth I; The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.; Institute of Medical and Human Genetics, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany., Eckardt R; The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany., Eriksson JG; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki, Finland.; Folkhälsan Research Centre, FI-00290 Helsinki, Finland., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA., Franco OH; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Froguel P; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Gansevoort RT; University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, 5000 Odense, Denmark., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA., Hastie N; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Heliövaara M; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Hofman A; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Jordan JM; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA., Jula A; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, FI-33521 Tampere, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, FI-33014 Tampere, Finland., Kajantie E; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Children's Hospital, Helsinki University Hospital and University of Helsinki, FI-00029 Helsinki, Finland.; Department of Obstetrics and Gynecology, MRC Oulu, Oulu University Hospital and University of Oulu, FI-90029 Oulu, Finland., Knekt PB; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Koskinen S; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kovacs P; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany., Lehtimäki T; Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, FI-33520 Tampere, Finland., Lind L; Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden., Liu Y; Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA., Orwoll ES; Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA., Osmond C; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK., Perola M; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia.; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Pérusse L; Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6.; Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec, Canada G1V 0A6., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FI-20520 Turku, Finland., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA., Rao DC; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA., Rice TK; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA., Rivadeneira F; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK., Salomaa V; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Sørensen TI; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, 2000 Frederiksberg, Denmark., Stumvoll M; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.; University of Leipzig, Department of Medicine, 04103 Leipzig, Germany., Tönjes A; University of Leipzig, Department of Medicine, 04103 Leipzig, Germany., Towne B; Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA., Tranah GJ; California Pacific Medical Center Research Institute, San Francisco, California 94107, USA., Tremblay A; Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6., Uitterlinden AG; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, 3501 DG Utrecht, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Vartiainen E; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Viikari JS; Department of Medicine, University of Turku, FI-20521 Turku, Finland., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Vohl MC; Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec, Canada G1V 0A6.; School of Nutrition, Laval University, Québec City, Quebec, Canada G1V 0A6., Völzke H; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, 17475 Greifswald, Germany.; DZD (German Centre for Diabetes Research), partner site Greifswald, 17475 Greifswald, Germany., Walker M; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.; Institute of Cellular Medicine, Newcastle University, Newcastle NE2 4HH, UK., Wallaschofski H; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, 17475 Greifswald, Germany., Wild S; Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK., Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK., Yengo L; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Bishop DT; Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.; Analytical Genetics Group, Regeneron Genetics Center, Regeneron Pharmaceuticals, Inc., Tarrytown, New York 10591, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.; Imperial College Healthcare NHS Trust, London W12 0HS, UK., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA., Dehghan A; Department of Epidemiology, Erasmus Medical Center, 3000CA Rotterdam/Zuidholland, The Netherlands., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 21589, Saudi Arabia., Fatemifar G; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited., Fox C; Harvard Medical School, Boston, Massachusetts 02115, USA.; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA., Furey TS; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.; Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Franke L; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Han J; Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202, USA., Hunter DJ; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Karjalainen J; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford OX3 7LJ, UK., Kaplan RC; Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA., Kooner JS; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.; Imperial College Healthcare NHS Trust, London W12 0HS, UK.; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford OX3 7LJ, UK., Murabito JM; Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, Massachusetts 02118, USA.; NHLBI's and Boston University's Framingham Heart Study, Framingham, Massachusetts 01702, USA., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK., Bishop JA; Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK., North KE; Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7400, USA., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden., Ong KK; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.; MRC Unit for Lifelong Health and Ageing at UCL, London WC1B 5JU, UK.; Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK., Prokopenko I; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK., Richards JB; Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.; Department of Medicine, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.; Department of Twin Research, King's College London, London SE1 1E7, UK.; Division of Endocrinology, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2., Schadt EE; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Widén E; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA., Yang J; Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia., Ingelsson E; Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, 751 85 Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Hirschhorn JN; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA., Pospisilik JA; Department of Epigenetics, Max Planck Institute of Immunobiology and Epigenetics, D-76108 Freiburg, Germany., Zillikens MC; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands., Lindgren C; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.; The Big Data Institute, University of Oxford, Oxford OX3 7LJ, UK., Kilpeläinen TO; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Loos RJ; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, 10029, USA.; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Publikováno v:
Nature communications [Nat Commun] 2016 Feb 01; Vol. 7, pp. 10495. Date of Electronic Publication: 2016 Feb 01.
Autor:
Pattaro C; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy., Teumer A; Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.; Institute for Community Medicine, University of Greifswald, Walther-Rathenau-Strasse 48, Greifswald 17487, Germany., Gorski M; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.; Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany., Chu AY; Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA., Li M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA., Mijatovic V; Department of Life and Reproduction Sciences, University of Verona, Strada Le Grazie 8, Verona 37134, Italy., Garnaas M; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, New Research Building77 Avenue Louis Pasteur, Room 458, Boston, Massachusetts 02115, USA., Tin A; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA., Sorice R; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Via P. Castellino 111, Napoli 80131, Italy., Li Y; Department of Internal Medicine IV, University Hospital Freiburg, Berliner Allee 29, Freiburg 79110, Germany., Taliun D; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy., Olden M; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.; Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany., Foster M; Division of Nephrology/Tufts Evidence Practice Center, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA., Yang Q; Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, Massachusetts 02118, USA., Chen MH; Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, Massachusetts 02118, USA.; Department of Neurology, Boston University School of Medicine, 72 East Concord ST B603, Boston, Massachusetts 02118, USA., Pers TH; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 2142, USA., Johnson AD; NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA., Ko YA; Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA., Fuchsberger C; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy., Tayo B; Department of Public Health Sciences, Loyola Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA., Nalls M; Laboratory of Neurogenetics, Building 35-Porter Building, 1A1015, National Institute on Aging/NIH, Bethesda, Maryland 20892, USA., Feitosa MF; Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Box 8506, St Louis, Missouri 63108, USA., Isaacs A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.; Centre for Medical Systems Biology Leiden, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands., Dehghan A; Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands., d'Adamo P; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo' and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy., Adeyemo A; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA., Dieffenbach AK; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.; German Cancer Consortium (DKTK), Im Neuenheimer Feld 581, Heidelberg 69120, Germany., Zonderman AB; Laboratory of Personality and Cognition, National Institute on Aging, National Institutes of Health, NIH Biomedical Center, 251 Bayview Boulevard, Suite 100, Baltimore, Maryland 21224, USA., Nolte IM; Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands., van der Most PJ; Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK., Shuldiner AR; Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.; Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, 10 North Greene Street, Baltimore, Maryland 21201, USA., Morrison AC; Human Genetics Center, University of Texas Health Science Center at Houston, 1200 Pressler St Suite 453E, Houston, Texas 77030, USA., Hofman A; Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands., Smith AV; Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.; University of Iceland, Sæmundargötu 2, Reykjavik 101, Iceland., Dreisbach AW; Division of Nephrology, University of Mississippi, 2500 North State Street, Jackson, Mississippi 39216, USA., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts University of Kiel, Schittenhelmstraße 12, Kiel 24105, Germany., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands., Metspalu A; Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.; Institute of Molecular and Cell Biology, University of Tartu and Estonian Biocenter, Riia 23, Tartu 51010, Estonia., Tonjes A; Department of Medicine, University of Leipzig, Liebigstraße 18, Leipzig 04103, Germany., Lupo A; Division of Nephrology, Department of Medicine, University of Verona, Piazzale Aristide Stefani 1, Verona 37126, Italy., Robino A; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo' and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy., Johansson Å; Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden., Demirkan A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands., Kollerits B; Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria., Freedman BI; Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA., Ponte B; Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospital, 4 rue Gabrielle-Perret-Gentil, Geneve 1211, Switzerland., Oostra BA; Department of Clinical Genetics, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands., Paulweber B; First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Müllner Hauptstraße 48, Salzburg 5020, Austria., Krämer BK; University Medical Centre Mannheim, 5th Department of Medicine, University of Heidelberg, Theodor Kutzer Ufer 1-3, Mannheim 68167, Germany., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.; Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, 10 North Greene Street, Baltimore, Maryland 21201, USA., Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Clinical Investigations Building, Western Rd, Cork, Ireland., Peralta CA; Division of Nephrology, University of California, San Francisco Medical School and San Francisco VA Medical Center, 4150 Clement Street, San Francisco, California 94121, USA., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK., Helmer C; INSERM, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux F-33000, France.; Université Bordeaux, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux F-33000, France., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA., Shaffer CM; Vanderbilt University School of Medicine, 2215-B Garland Avenue 1224-MRB4 (Light Hall)Nashville, Tennessee 37232, USA., Müller C; University Heart Center Hamburg, Clinic for general and interventional cardiology, Martinistraße 52, Hamburg 20246, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, Martinistraße 52, Hamburg 20246, Germany., Sala C; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands., Saint-Pierre A; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.; INSERM U1078, Etablissement Français du Sang, 46 rue Félix Le Dantec, CS 51819, Brest Cedex 2 29218, France., Ackermann D; Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospital, 4 rue Gabrielle-Perret-Gentil, Geneve 1211, Switzerland., Shriner D; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA., Ruggiero D; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Via P. Castellino 111, Napoli 80131, Italy., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.; Institute of Molecular Genetics-CNR, Via Abbiategrasso 207, Pavia 27100, Italy., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Cusi D; Department of Health Sciences, University of Milano, Via Antonio di Rudinì 8, Milano 20142, Italy., Czamara D; Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, Munich 80804, Germany., Ellinghaus D; Institute of Clinical Molecular Biology, Christian-Albrechts University of Kiel, Schittenhelmstraße 12, Kiel 24105, Germany., Siscovick DS; Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, Washington 98101, USA., Ruderfer D; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.; German Center for Diabetes Research (DZD), Ingolstaedter Landstraße 1, Neuherberg 85764, Germany., Rochtchina E; Westmead Millennium Institute, Centre for Vision Research, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia., Atkinson EJ; Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA., Holliday EG; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia.; Clinical Research Design, Information Technology and Statistical Support, Hunter Medical Research Institute, Newcastle, 1 Kookaburra Circuit, New Lambton Heights, New South Wales 2305, Australia., Boerwinkle E; Human Genetics Center, University of Texas Health Science Center at Houston, 1200 Pressler St Suite 453E, Houston, Texas 77030, USA., Salvi E; Department of Health Sciences, University of Milano, Via Antonio di Rudinì 8, Milano 20142, Italy., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Murgia F; Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy., Rivadeneira F; Department of Internal Medicine, Erasmus University Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands., Ernst F; Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany., Kronenberg F; Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria., Hu FB; Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, Massachusetts 02115, USA., Navis GJ; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands., Curhan GC; Brigham and Women's Hospital and Channing Laboratory, Harvard Medical School, 181 Longwood Avenue, Boston, Massachusetts 02115, USA., Ehret GB; Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, Geneva 1205, Switzerland., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany., Coassin S; Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria., Thun GA; Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.; University of Basel, Petersplatz 1, Basel 4003, Switzerland., Pistis G; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy., Gambaro G; Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Via Moscati 31, Rome 00168, Italy., Malerba G; Department of Life and Reproduction Sciences, University of Verona, Strada Le Grazie 8, Verona 37134, Italy., Montgomery GW; Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia., Eiriksdottir G; Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland., Jacobs G; Institute of Epidemiology and Biobank popgen, Christian-Albrechts University, Niemannsweg 11, Kiel 24105, Germany., Li G; Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, Washington 98101, USA., Wichmann HE; Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, Neuherberg 85764, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.; Klinikum Grosshadern, Ingolstädter Landstraße 1, Neuherberg 85764, Germany., Campbell H; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK., Schmidt H; Austrian Stroke Prevention Study, Institute of Molecular Biology and Biochemistry, Department of Neurology, Medical University Graz, Harrachgasse 21, Graz 8010, Austria., Wallaschofski H; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.; German Center for Cardiovascular Research (DZHK), Partner site Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany., Völzke H; Institute for Community Medicine, University of Greifswald, Walther-Rathenau-Strasse 48, Greifswald 17487, Germany.; German Center for Cardiovascular Research (DZHK), Partner site Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.; German Cancer Consortium (DKTK), Im Neuenheimer Feld 581, Heidelberg 69120, Germany., Kroemer HK; Institute of Pharmacology, University of Greifswald, Friedrich-Loeffler-Straße 23d, Greifswald 17487, Germany., Kramer H; Department of Public Health Sciences, Loyola Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA., Lin H; Boston University School of Medicine, 72 East Concord Street, B-616, Boston, Massachusetts 02118, USA., Leach IM; Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen 9700 RB, The Netherlands., Ford I; Robertson Centre for Biostatistics, University of Glasgow, R1122B Level 11, Robertson Centre, Boyd Orr Building, Glasgow G12 8QQ, UK., Guessous I; Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva 1211, Switzerland.; Community Prevention Unit, University Institute of Social and Preventive Medicine, Lausanne University Hospital, Route de la Corniche 10, Lausanne 1010, Switzerland.; Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, Georgia 30322, USA., Rudan I; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK., Prokopenko I; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK., Borecki I; Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Box 8506, St Louis, Missouri 63108, USA., Heid IM; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany., Kolcic I; Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia., Persico I; Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy., Jukema JW; Department of Cardiology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands.; Interuniversity Cardiology Institute of the Netherlands (ICIN), Moreelsepark 1, Utrecht 3511 EP, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.; Durrer Center for Cardiogenetic Research, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands., Wilson JF; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK., Felix JF; Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands., Divers J; Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University Health Sciences, 2326 Medical Center Boulevard, Winston-Salem, North Carolina 27157-1063, USA., Lambert JC; INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France., Stafford JM; Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University Health Sciences, 2326 Medical Center Boulevard, Winston-Salem, North Carolina 27157-1063, USA., Gaspoz JM; Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva 1211, Switzerland., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, Michigan 48109-2029, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, 426 Thompson Street, #3456, Ann Arbor, Michigan 48104, USA., Wang JJ; Centre for Vision Research, Westmead Millennium Institute, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia., Ding J; Wake Forest School of Medicine, Department of Internal Medicine/Geriatrics, Medical center Boulevard, Winston-Salem, North Carolina 27157, USA., Hirschhorn JN; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 2142, USA.; Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, NRB 0330, Boston, Massachusetts 02115, USA., Attia J; Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia., Whitfield JB; Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia., Chalmers J; University of Sydney, The George Institute for Global Health, Level 10, King George V Building, 83-117 Missenden Road, Camperdown, New South Wales 2050, Australia., Viikari J; Department of Medicine, University of Turku, Turku University Hospital, PO Box 52, Turku 20521, Finland., Coresh J; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.; Welch Center for Prevention, Epidemiology and Clinical Research, 2024 East Monument St, Suite 2-600, Baltimore, Maryland 21287, USA., Denny JC; Vanderbilt University School of Medicine, 448 Eskind Biomedical Library, 2209 Garland Avenue, Nashville, Tennessee 37212, USA., Karjalainen J; Department of Genetics, University of Groningen, University Medical Centre Groningen, PO Box 72, Groningen 9700 AB, The Netherlands., Fernandes JK; Division of Endocrinology, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina 29425, USA., Endlich K; Institute of Anatomy and Cell Biology, University of Greifswald, Friedrich-Loeffler-Straße 23c, Greifswald 17487, Germany., Butterbach K; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany., Keene KL; Center for Health Disparities, Department of Biology, East Carolina University, 1001 East 10th Street, N209 Howell Science Complex Mailstop 551, Greenville, North Carolina 27858, USA., Lohman K; Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA., Portas L; Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy., Launer LJ; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Gateway Building, 3C309, 7201 Winsconsin Avenue, Bethesda, Maryland 20892-9205, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine, Tampere 33520, Finland., Yengo L; CNRS UMR 8199, 1 Rue du Professeur Calmette, Lille 59000, France.; Lille Pasteur Institute, 1 Rue du Professeur Calmette, Lille 59000, France.; Lille II University, 42 Rue paul Duez, Lille 59000, France., Franke L; Department of Genetics, University of Groningen, University Medical Centre Groningen, PO Box 72, Groningen 9700 AB, The Netherlands., Ferrucci L; Clinical Research Branch, National Institute on Aging, 251 Bayview Blvd, Baltimore, Maryland 21250, USA., Rose LM; Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA., Kedenko L; First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Müllner Hauptstraße 48, Salzburg 5020, Austria., Rao M; Division of Nephrology/Tufts Evidence Practice Center, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA., Struchalin M; Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Dr Molewaterplein, Rotterdam 50-603015 GE, The Netherlands.; Department of Forensic Molecular Biology, Erasmus University Medical Center, Dr Molewaterplein, Rotterdam 50-603015 GE, The Netherlands., Kleber ME; Medical Clinic V, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany., Cavalieri M; Austrian Stroke Prevention Study, Department of Neurology, Division of Special Neurology, Medical University Graz, Auenbruggerplatz 22, Graz 8036, Austria., Haun M; Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria., Cornelis MC; Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, Massachusetts 02115, USA., Ciullo M; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Via P. Castellino 111, Napoli 80131, Italy., Pirastu M; Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy., de Andrade M; Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA., McEvoy MA; Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1, HRMC, New South Wales 2310, Australia., Woodward M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.; University of Sydney, The George Institute for Global Health, Level 10, King George V Building, 83-117 Missenden Road, Camperdown, New South Wales 2050, Australia.; Department of Medicine, University of Turku, Turku University Hospital, PO Box 52, Turku 20521, Finland.; The George Institute for Global Health, Nuffield Department of Population Health, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford OX3 7LF, UK., Adam M; Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.; University of Basel, Petersplatz 1, Basel 4003, Switzerland., Cocca M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy., Nauck M; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.; German Center for Cardiovascular Research (DZHK), Partner site Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany., Imboden M; Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.; University of Basel, Petersplatz 1, Basel 4003, Switzerland., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany., Pruijm M; Service of Nephrology, Lausanne University Hospital, Rue du Bugnon 17, Lausanne 1005, Switzerland., Metzger M; Inserm UMRS 1018, CESP Team 10, Université Paris-Sud, 16 avenue Paul Vaillant Couturier, Villejuif 94807, France., Stumvoll M; Department of Medicine, University of Leipzig, Liebigstraße 18, Leipzig 04103, Germany., Evans MK; Health Disparities Research Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, NIH Biomedical Center, 251 Bayview Boulevard, Suite 100, Baltimore, Maryland 21224, USA., Sale MM; Center for Public Health Genomics, Department of Medicine (Cardiovascular Medicine), University of Virginia, PO Box 800717, Charlottesville, Virginia 22908, USA., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, University of Tampere, School of Medicine, Tampere 33521, Finland., Boban M; Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia., Bochud M; University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Route de la Corniche 2, Epalinges CH-1066, Switzerland., Rheinberger M; Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany., Verweij N; Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen 9700 RB, The Netherlands., Bouatia-Naji N; INSERM UMR970, Paris Cardiovascular Research Center (PARCC), 56 rue Leblanc, Paris F-75015, France.; Paris Descartes University, Faculty of medicine, Paris Cité Sorbonne, 12 Rue de l'école de Médecine, Paris F-75006, France., Martin NG; Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.; Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA., Hastie N; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK., Probst-Hensch N; Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.; University of Basel, Petersplatz 1, Basel 4003, Switzerland., Soranzo N; Wellcome Trust Sanger Institute, Hinxton CB10 1HH, UK., Devuyst O; University of Zurich, Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, Winterthurerstrasse 190, Zürich 8057, Switzerland., Raitakari O; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku University Hospital, Department of Clinical Physiology, PO Box 52, Turku 20521, Finland., Gottesman O; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Franco OH; Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands., Polasek O; Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia., Gasparini P; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo' and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy., Munroe PB; Department Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK., Ridker PM; Harvard Medical School, 900 Commonwealth Avenue East, Boston, Massachusetts 02115, USA., Mitchell P; Centre for Vision Research, Westmead Millennium Institute, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia., Muntner P; University of Alabama at Birmingham, Department of Medicine, 1530 3rd Avenue, South Birmingham, Alabama 35294-0022, USA.; University of Alabama at Birmingham, Department of Epidemiology, 1530 3rd Avenue, South Birmingham, Alabama 35294-0022, USA., Meisinger C; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany., Smit JH; Department of Psychiatry and EMGO+ Institute, VU University Medical Center, A.J. Ernststraat 1187, Amsterdam 1081 HL, The Netherlands., Kovacs P; IFB AdiposityDiseases, University of Leipzig, Liebigstraße 21, Leipzig 04103, Germany., Wild PS; Medical University Center Mainz, Langenbeckstraße 1, Mainz 55131, Germany., Froguel P; CNRS UMR 8199, 1 Rue du Professeur Calmette, Lille 59000, France.; Lille Pasteur Institute, 1 Rue du Professeur Calmette, Lille 59000, France.; Lille II University, 42 Rue paul Duez, Lille 59000, France., Rettig R; Institute of Physiology, University of Greifswald, Greifswald 17487, Germany., Mägi R; Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia., Biffar R; Clinic for Prosthodontic Dentistry, Gerostomatology and Material Science, University of Greifswald, Rotgerberstraße 8, Greifswald 17475, Germany., Schmidt R; Austrian Stroke Prevention Study, Department of Neurology, Division of Special Neurology, Medical University Graz, Auenbruggerplatz 22, Graz 8036, Austria., Middelberg RP; Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia., Carroll RJ; Vanderbilt University School of Medicine, 448 Eskind Biomedical Library, 2209 Garland Avenue, Nashville, Tennessee 37212, USA., Penninx BW; Department of Psychiatry and EMGO+ Institute, VU University Medical Center, A.J. Ernststraat 1187, Amsterdam 1081 HL, The Netherlands., Scott RJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1, HRMC, New South Wales 2310, Australia., Katz R; Kidney Research Institute, University of Washington, Box 359606, 325 9th Avenue, Seattle, Washington 98104, USA., Sedaghat S; Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands., Wild SH; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK., Kardia SL; Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, Michigan 48109-2029, USA., Ulivi S; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Via dell'Istria 65, Trieste 34137, Italy., Hwang SJ; NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA., Enroth S; Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden., Kloiber S; Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, Munich 80804, Germany., Trompet S; Department of Cardiology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands., Stengel B; Inserm UMRS 1018, CESP Team 10, Université Paris-Sud, 16 avenue Paul Vaillant Couturier, Villejuif 94807, France., Hancock SJ; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia.; Clinical Research Design, Information Technology and Statistical Support, Hunter Medical Research Institute, Newcastle, 1 Kookaburra Circuit, New Lambton Heights, New South Wales 2305, Australia., Turner ST; Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA., Rosas SE; Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA., Stracke S; INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.; Clinic for Internal Medicine A, University of Greifswald, Friedrich-Loeffler-Straße 23a, Greifswald 17475, Germany., Harris TB; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Gateway Building, 3C309, 7201 Winsconsin Avenue, Bethesda, Maryland 20892-9205, USA., Zeller T; University Heart Center Hamburg, Clinic for general and interventional cardiology, Martinistraße 52, Hamburg 20246, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, Martinistraße 52, Hamburg 20246, Germany., Zemunik T; Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine, Tampere 33520, Finland., Illig T; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany., Aspelund T; Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.; University of Iceland, Sæmundargötu 2, Reykjavik 101, Iceland., Nikopensius T; Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.; Institute of Molecular and Cell Biology, University of Tartu and Estonian Biocenter, Riia 23, Tartu 51010, Estonia., Esko T; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.; Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.; Institute of Molecular and Cell Biology, University of Tartu and Estonian Biocenter, Riia 23, Tartu 51010, Estonia., Tanaka T; Clinical Research Branch, National Institute on Aging, 251 Bayview Blvd, Baltimore, Maryland 21250, USA., Gyllensten U; Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden., Völker U; Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.; German Center for Cardiovascular Research (DZHK), Partner site Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany., Emilsson V; Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.; Faculty of Pharmaceutical Sciences, University of Iceland, Sæmundargata 2, Reykjavik 101, Iceland., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK., Aalto V; Department of Clinical Physiology, Turku University Hospital, Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, PO Box 52, Turku 20521, Finland., Gudnason V; Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.; University of Iceland, Sæmundargötu 2, Reykjavik 101, Iceland., Chouraki V; INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France., Chen WM; Center for Public Health Genomics, Department of Medicine (Cardiovascular Medicine), University of Virginia, PO Box 800717, Charlottesville, Virginia 22908, USA., Igl W; Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden., März W; Synlab Academy, Synlab Services GmbH, Oberer Eselsberg 45, Ulm 89081, Germany., Koenig W; Department of Internal Medicine II-Cardiology, University of Ulm Medical Centre, Albert-Einstein-Allee 23, Ulm 89081, Germany., Lieb W; Institute of Epidemiology and Biobank popgen, Christian-Albrechts University, Niemannsweg 11, Kiel 24105, Germany., Loos RJ; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Mindich Child Health and Development Institute, Ichan School of Medicine at Mount Sinai, New York, New York 10029, USA., Liu Y; Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA., Snieder H; Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands., Pramstaller PP; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.; Department of Neurology, General Central Hospital, Via Lorenz Bohler 5, Bolzano 39100, Italy.; Department of Neurology, University of Lübeck, Ratzeburger Allee 160, Lübeck 23538, Germany., Parsa A; University of Maryland Medical School, Division of Nephrology, 685 W. Baltimore Street, MSTF 314, Baltimore, Maryland 21201, USA., O'Connell JR; Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA., Susztak K; Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA., Hamet P; CRCHUM, University of Montreal, CHUM Research Center, Technopôle Angus, 900 Saint-Denis, Montreal, Québec, Canada H2X 0A9., Tremblay J; CRCHUM, University of Montreal, CHUM Research Center, Technopôle Angus, 900 Saint-Denis, Montreal, Québec, Canada H2X 0A9., de Boer IH; Kidney Research Institute, University of Washington, Box 359606, 325 9th Avenue, Seattle, Washington 98104, USA., Böger CA; Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany., Goessling W; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, New Research Building77 Avenue Louis Pasteur, Room 458, Boston, Massachusetts 02115, USA., Chasman DI; Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.; Harvard Medical School, 900 Commonwealth Avenue East, Boston, Massachusetts 02115, USA., Köttgen A; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.; Department of Internal Medicine IV, University Hospital Freiburg, Berliner Allee 29, Freiburg 79110, Germany., Kao WH; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.; Welch Center for Prevention, Epidemiology and Clinical Research, 2024 East Monument St, Suite 2-600, Baltimore, Maryland 21287, USA., Fox CS; NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.; Division of Endocrinology, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, Massachusetts 02115, USA.
Publikováno v:
Nature communications [Nat Commun] 2016 Jan 21; Vol. 7, pp. 10023. Date of Electronic Publication: 2016 Jan 21.
Autor:
van Leeuwen EM; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Karssen LC; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Deelen J; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Isaacs A; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Medina-Gomez C; Department of Epidemiology and Internal Medicine, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Mbarek H; Department of Biological Psychology, VU University Amsterdam and EMGO+ Institute for Health and Care Research, Amsterdam 1081BT, The Netherlands., Kanterakis A; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Postmus I; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Verweij N; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, The Netherlands., van Enckevort DJ; BioAssist, Netherlands Bioinformatics Center, Nijmegen 6500 HB, The Netherlands., Huffman JE; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK., White CC; Department of Biostatistics, Boston U School of Public Health, Boston, Massachusetts 02118, USA., Feitosa MF; Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA., Bartz TM; Department of Biostatistics and Medicine, University of Washington, Seattle, Washington 98101, USA., Manichaikul A; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia 22908, USA., Joshi PK; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland EH8 9AG, UK., Peloso GM; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02176, USA., Deelen P; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., van Dijk F; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., Willemsen G; Department of Biological Psychology, VU University Amsterdam and EMGO+ Institute for Health and Care Research, Amsterdam 1081BT, The Netherlands., de Geus EJ; Department of Biological Psychology, VU University Amsterdam and EMGO+ Institute for Health and Care Research, Amsterdam 1081BT, The Netherlands., Milaneschi Y; Department of Psychiatry, VU University Medical Center Amsterdam/GGZinGeest, EMGO+ Institute for Health and Care Research, Neuroscience Campus Amsterdam, Amsterdam 1081HL, The Netherlands., Penninx BW; Department of Psychiatry, VU University Medical Center Amsterdam/GGZinGeest, EMGO+ Institute for Health and Care Research, Neuroscience Campus Amsterdam, Amsterdam 1081HL, The Netherlands., Francioli LC; Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht 3584 CG, The Netherlands., Menelaou A; Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht 3584 CG, The Netherlands., Pulit SL; Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht 3584 CG, The Netherlands., Rivadeneira F; Department of Epidemiology and Internal Medicine, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Hofman A; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Oostra BA; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Franco OH; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Mateo Leach I; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, The Netherlands., Beekman M; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., de Craen AJ; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Uh HW; Department of Genetical Statistics, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Trochet H; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK., Hocking LJ; Division of Applied Health Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK., Porteous DJ; Centre for Genomic and Experimental Medicine, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK., Sattar N; BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University of Glasgow, Glasgow G12 8QQ, UK., Packard CJ; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland., Brody JA; Department of Medicine, University of Washington, Seattle, Washington 98101, USA., Bis JC; Department of Medicine, University of Washington, Seattle, Washington 98101, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Mychaleckyj JC; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia 22908, USA., Campbell H; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland EH8 9AG, UK., Duan Q; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina NC 27599, USA., Lange LA; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina NC 27599, USA., Wilson JF; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland EH8 9AG, UK., Hayward C; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia., Vitart V; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK., Rudan I; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland EH8 9AG, UK., Wright AF; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK., Rich SS; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia 22908, USA., Psaty BM; Department of Medicine and Epidemiology, University of Washington, Seattle, Washington 98101, USA., Borecki IB; Department of Genetics and Biostatistics, Washington University School of Medicine, St Louis, Missouri 63108, USA., Kearney PM; Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland., Stott DJ; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Adrienne Cupples L; 1] Department of Biostatistics, Boston U School of Public Health, Boston, Massachusetts 02118, USA [2] Framingham Heart Study, Framingham, Massachusetts 01702, USA., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., van der Harst P; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, The Netherlands., Sijbrands EJ; Department of Internal Medicine, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Hottenga JJ; Department of Biological Psychology, VU University Amsterdam and EMGO+ Institute for Health and Care Research, Amsterdam 1081BT, The Netherlands., Uitterlinden AG; Department of Epidemiology and Internal Medicine, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Swertz MA; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., van Ommen GJ; Department of Human Genetics, Leiden University Medical Center, Leiden P.O. Box 9600, 2300 RC, The Netherlands., de Bakker PI; 1] Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht 3584 CG, The Netherlands [2] Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht 3584 CG, The Netherlands., Eline Slagboom P; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Boomsma DI; Department of Biological Psychology, VU University Amsterdam, Amsterdam 1081BT, The Netherlands., Wijmenga C; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., van Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands.
Publikováno v:
Nature communications [Nat Commun] 2015 Mar 09; Vol. 6, pp. 6065. Date of Electronic Publication: 2015 Mar 09.
Autor:
Wessel J; 1] Department of Epidemiology, Fairbanks School of Public Health, Indianapolis, Indiana 46202, USA [2] Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA., Chu AY; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA [2] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA., Willems SM; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands [2] MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Wang S; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Brody JA; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Medicine, University of Washington, Seattle, Washington 98195, USA., Dauriz M; 1] Massachusetts General Hospital, General Medicine Division, Boston, Massachusetts 02114, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Verona Medical School and Hospital Trust of Verona, Verona 37126, Italy., Hivert MF; 1] Harvard Pilgrim Health Care Institute, Department of Population Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA [2] Division of Endocrinology and Metabolism, Department of Medicine, Université de Sherbrooke, Sherbrooke, Québec, Canada J1K 2R1 [3] Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Raghavan S; 1] Massachusetts General Hospital, General Medicine Division, Boston, Massachusetts 02114, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA., Lipovich L; 1] Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA [2] Department of Neurology, Wayne State University School of Medicine, Detroit, Michigan 48202, USA., Hidalgo B; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA., Fox K; 1] Department of Medicine, University of Washington, Seattle, Washington 98195, USA [2] Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA., Huffman JE; 1] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, Scotland EH4 2XU, UK., An P; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Lu Y; 1] The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Ehm MG; Quantitative Sciences, PCPS, GlaxoSmithKline, North Carolina 27709, USA., Li L; Quantitative Sciences, PCPS, GlaxoSmithKline, North Carolina 27709, USA., Baldridge AS; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA., Stančáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio FI-70211, Finland., Abrol R; 1] Department of Medicine and Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA [2] Materials and Process Simulation Center, California Institute of Technology, Pasadena, California 91125, USA., Besse C; CEA, Institut de Génomique, Centre National de Génotypage, 2 Rue Gaston Crémieux, EVRY Cedex 91057, France., Boland A; CEA, Institut de Génomique, Centre National de Génotypage, 2 Rue Gaston Crémieux, EVRY Cedex 91057, France., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Fornage M; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas 77030, USA., Freitag DF; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge, Cambridge CB1 8RN, UK., Garcia ME; Intramural Research Program, National Institute on Aging, Bethesda, Maryland 21224, USA., Guo X; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Hara K; 1] The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Isaacs A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Jakobsdottir J; Icelandic Heart Association, Holtasmari 1, Kopavogur IS-201, Iceland., Lange LA; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Layton JC; Indiana University, Fairbanks School of Public Health, Indianapolis, Indiana 46202, USA., Li M; Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland 21205, USA., Hua Zhao J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal DE-14558, Germany., Morrison AC; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77225, USA., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland 20892, USA., Peters MJ; 1] Department of Internal Medicine, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands [2] The Netherlands Genomics Initiative-sponsored Netherlands Consortium for Healthy Aging (NGI-NCHA), Leiden/Rotterdam 2300 RC, The Netherlands., Sabater-Lleal M; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Schurmann C; 1] The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Silveira A; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Smith AV; 1] Icelandic Heart Association, Holtasmari 1, Kopavogur IS-201, Iceland [2] University of Iceland, Reykjavik IS-101, Iceland., Southam L; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, UK., Stoiber MH; Department of Genome Dynamics, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA., Strawbridge RJ; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Taylor KD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital, Malmö SE-205 02, Sweden., Allin KH; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Aponte JL; Quantitative Sciences, PCPS, GlaxoSmithKline, North Carolina 27709, USA., Aung T; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore., Barbieri C; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milano 20132, Italy., Bihlmeyer NA; 1] Predoctoral Training Program in Human Genetics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Maryland 21205, USA [2] McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Bombieri C; Section of Biology and Genetics, Department of Life and Reproduction Sciences, University of Verona, Verona 37100, Italy., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA., Burns SM; Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Chen Y; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Chen YD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Cheng CY; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore [3] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 119228, Singapore [4] Office of Clinical Sciences, Duke-NUS Graduate Medical School, National University of Singapore, Singapore 169857, Singapore., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA., Czajkowski J; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Dehghan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Ehret GB; 1] McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA [2] Division of Cardiology, Geneva University Hospital Geneva 1211, Switzerland., Eiriksdottir G; Icelandic Heart Association, Holtasmari 1, Kopavogur IS-201, Iceland., Escher SA; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital, Malmö SE-205 02, Sweden., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens 17671, Greece., Frånberg M; 1] Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden [2] Department of Numerical Analysis and Computer Science, SciLifeLab, Stockholm University, Stockholm SE-106 91, Sweden., Gambaro G; Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Rome 00168, Italy., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA., Goddard WA 3rd; Materials and Process Simulation Center, California Institute of Technology, Pasadena, California 91125, USA., Goel A; Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Gottesman O; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Grove ML; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77225, USA., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala SE-751 85, Sweden., Hai Y; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Hallmans G; Department of Biobank Research, Umeå University, Umeå SE-901 87, Sweden., Heo J; Department of Biomedical Technology, Sangmyung University, Chungnam 330-720, Korea., Hoffmann P; 1] Institute of Human Genetics, Department of Genomics, Life &Brain Center, University of Bonn, Bonn DE-53127, Germany [2] Human Genomics Research Group, Division of Medical Genetics, University Hospital Basel Department of Biomedicine 4031, Basel, Switzerland [3] Institute of Neuroscience and Medicine (INM-1) Genomic Imaging Research Center Juelich, Juelich DE-52425, Germany., Ikram MK; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Office of Clinical Sciences, Duke-NUS Graduate Medical School, National University of Singapore, Singapore 169857, Singapore [3] Memory Aging &Cognition Centre (MACC), National University Health System, Singapore 117599, Singapore., Jensen RA; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Medicine, University of Washington, Seattle, Washington 98195, USA., Jørgensen ME; Steno Diabetes Center, Gentofte DK-2820, Denmark., Jørgensen T; 1] Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup DK-2600, Denmark [2] Faculty of Medicine, University of Aalborg, Aalborg DK-9220, Denmark., Karaleftheri M; Echinos Medical Centre, Echinos 67300, Greece., Khor CC; 1] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore [2] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 119228, Singapore [3] Division of Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore., Kirkpatrick A; Materials and Process Simulation Center, California Institute of Technology, Pasadena, California 91125, USA., Kraja AT; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio FI-70211, Finland., Lange EM; 1] Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA [2] Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Lee IT; 1] Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 407, Taiwan [2] School of Medicine, National Yang-Ming University, Taipei 112, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung 407, Taiwan., Leong A; 1] Massachusetts General Hospital, General Medicine Division, Boston, Massachusetts 02114, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA., Liao J; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore., Liu C; National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA., Liu Y; Department of Epidemiology &Prevention, Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina 27106, USA., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Linneberg A; 1] Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup DK-2600, Denmark [2] Department of Clinical Experimental Research, Copenhagen University Hospital Glostrup, Glostrup DK-2600, Denmark [3] Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Malerba G; Section of Biology and Genetics, Department of Life and Reproduction Sciences, University of Verona, Verona 37100, Italy., Mamakou V; 1] National and Kapodistrian University of Athens, Faculty of Medicine, Athens 115 27, Greece [2] Dromokaiteio Psychiatric Hospital, Athens 124 61, Greece., Marouli E; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens 17671, Greece., Maruthur NM; 1] Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [2] Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland 21205, USA., Matchan A; The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK., McKean-Cowdin R; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles 90033, USA., McLeod O; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Metcalf GA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Muzny DM; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA., Ntalla I; 1] Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens 17671, Greece [2] University of Leicester, Leicester LE1 7RH, UK., Palmer ND; 1] Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA [2] Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina 27106, USA., Pasko D; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Peter A; 1] Department of Internal Medicine, Division of Endocrinology, Metabolism, Pathobiochemistry and Clinical Chemistry and Institute of Diabetes Research and Metabolic Diseases, University of Tübingen, Tübingen DE-72076, Germany [2] German Center for Diabetes Research (DZD), Neuherberg DE-85764, Germany., Rayner NW; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, UK [3] The Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LE, UK., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital, Malmö SE-205 02, Sweden., Rice K; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA., Sala CF; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milano 20132, Italy., Sennblad B; 1] Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden [2] Science for Life Laboratory, Karolinska Institutet, Stockholm SE-171 77, Sweden., Serafetinidis I; Department of Gastroenterology, Gennimatas General Hospital, Athens 11527, Greece., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA., Soranzo N; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] Department of Hematology, Long Road, Cambridge CB2 0XY, UK., Speliotes EK; Department of Internal Medicine, Division of Gastroenterology and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA., Stahl EA; Division of Psychiatric Genomics, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Stirrups K; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UK., Tentolouris N; First Department of Propaedeutic and Internal Medicine, Athens University Medical School, Laiko General Hospital, Athens 11527, Greece., Thanopoulou A; Diabetes Centre, 2nd Department of Internal Medicine, National University of Athens, Hippokration General Hospital, Athens 11527, Greece., Torres M; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles 90033, USA., Traglia M; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milano 20132, Italy., Tsafantakis E; Anogia Medical Centre, Anogia 740 51, Greece., Javad S; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Yanek LR; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Zengini E; 1] Dromokaiteio Psychiatric Hospital, Athens 124 61, Greece [2] University of Sheffield, Sheffield S10 2TN, UK., Becker DM; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Bis JC; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Medicine, University of Washington, Seattle, Washington 98195, USA., Brown JB; 1] Department of Genome Dynamics, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA [2] Department of Statistics, University of California at Berkeley, Berkeley, California 94720, USA., Cupples LA; 1] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Hansen T; 1] The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark [2] Faculty of Health Science, University of Copenhagen, Copenhagen 1165, Denmark., Ingelsson E; 1] Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala SE-751 85, Sweden [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Karter AJ; Division of Research, Kaiser Permanente, Northern California Region, Oakland, California 94612, USA., Lorenzo C; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 77030, USA., Mathias RA; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Norris JM; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado 80204, USA., Peloso GM; 1] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Sheu WH; 1] Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 407, Taiwan [2] School of Medicine, National Yang-Ming University, Taipei 112, Taiwan [3] College of Medicine, National Defense Medical Center, Taipei 114, Taiwan., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milano 20132, Italy., Vaidya D; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Varma R; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles 90033, USA., Wagenknecht LE; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27106, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbrücke, Nuthetal DE-14558, Germany., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens 17671, Greece., Deloukas P; 1] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UK [2] Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK [3] Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 22254, Saudi Arabia., Ferrannini E; CNR Institute of Clinical Physiology, Pisa 73100, Italy., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Franks PW; 1] Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital, Malmö SE-205 02, Sweden [2] Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA [3] Department of Public Health &Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden., Gibbs RA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA., Gudnason V; 1] Icelandic Heart Association, Holtasmari 1, Kopavogur IS-201, Iceland [2] University of Iceland, Reykjavik IS-101, Iceland., Hamsten A; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Harris TB; Intramural Research Program, National Institute on Aging, Bethesda, Maryland 21224, USA., Hattersley AT; Genetics of Diabetes, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Hayward C; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, Scotland EH4 2XU, UK., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Jansson JH; 1] Department of Public Health &Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden [2] Research Unit, Skellefteå SE-931 87, Sweden., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Launer LJ; Intramural Research Program, National Institute on Aging, Bethesda, Maryland 21224, USA., Levy D; 1] Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA [2] Framingham Heart Study, Framingham, Massachusetts 01702, USA., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., O'Donnell CJ; 1] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., O'Rahilly S; University of Cambridge Metabolic Research Laboratories, MRC Metabolic Diseases Unit and NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 1TN, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia., Province MA; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Rich SS; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia 22908, USA., Ridker PM; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA [2] Division of Cardiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., Rudan I; Centre for Population Health Sciences, Medical School, University of Edinburgh, Edinburgh, Scotland EH8 9YL, UK., Schulze MB; 1] Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal DE-14558, Germany [2] German Center for Diabetes Research (DZD), Neuherberg DE-85764, Germany., Smith BH; Medical Research Institute, University of Dundee, Dundee DD1 9SY, UK., Uitterlinden AG; 1] Department of Internal Medicine, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands [2] Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Walker M; Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne NE1 7RU, UK., Watkins H; Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Wong TY; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore [3] Office of Clinical Sciences, Duke-NUS Graduate Medical School, National University of Singapore, Singapore 169857, Singapore., Zeggini E; The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio FI-70211, Finland., Borecki IB; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Chasman DI; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA [2] Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Psaty BM; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Medicine, University of Washington, Seattle, Washington 98195, USA [3] Department of Epidemiology, University of Washington, Seattle, Washington 98195, USA [4] Department of Health Services, University of Washington, Seattle, Washington 98195, USA [5] Group Health Research Institute, Group Health Cooperative, Seattle, Washington 98195, USA., Tai ES; 1] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 119228, Singapore [2] Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., van Duijn CM; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands [2] Center for Medical Systems Biology, Leiden 2300, The Netherlands., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Waterworth DM; Genetics, PCPS, GlaxoSmithKline, Philadelphia, Pennsylvania 19104, USA., Boerwinkle E; 1] Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77225, USA [2] Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA., Kao WH; 1] Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland 21205, USA [2] Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland 21205, USA [3] Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA., Florez JC; 1] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA [4] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Loos RJ; 1] The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [3] The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi 38677, USA., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Siscovick DS; 1] New York Academy of Medicine, New York, New York 10029, USA [2] Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, Washington 98195, USA., Dupuis J; 1] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Meigs JB; 1] Massachusetts General Hospital, General Medicine Division, Boston, Massachusetts 02114, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Goodarzi MO; 1] Department of Medicine and Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA [2] Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
Publikováno v:
Nature communications [Nat Commun] 2015 Jan 29; Vol. 6, pp. 5897. Date of Electronic Publication: 2015 Jan 29.
Autor:
Springelkamp H; 1] Department of Ophthalmology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [2] Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Höhn R; Department of Ophthalmology, University Medical Center Mainz, Mainz 55131, Germany., Mishra A; Department of Genetics and Computational Biology, Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Queensland 4006, Australia., Hysi PG; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK., Khor CC; 1] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119077, Singapore [2] Division of Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore., Loomis SJ; Department of Ophthalmology, Harvard Medical School and Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA., Bailey JN; 1] Department of Molecular Physiology and Biophysics, Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA [2] Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio 44106, USA., Gibson J; Centre for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton, Southampton SO17 1BJ, UK., Thorleifsson G; deCODE/Amgen, Reykjavik 101, Iceland., Janssen SF; Department of Clinical and Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam 1105 BA, the Netherlands., Luo X; Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina 27710, USA., Ramdas WD; Department of Ophthalmology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Vithana E; 1] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119077, Singapore [2] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [3] Duke-National University of Singapore, Graduate Medical School, Singapore 169857, Singapore., Nongpiur ME; 1] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119077, Singapore [2] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore., Montgomery GW; Department of Genetics and Computational Biology, Molecular Epidemiology Laboratory, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Queensland 4006, Australia., Xu L; 1] Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China [2] Beijing Ophthalmology and Visual Science Key Lab, Beijing 100730, China., Mountain JE; Telethon Institute for Child Health Research, Subiaco, Western Australia 6008, Australia., Gharahkhani P; Department of Genetics and Computational Biology, Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Queensland 4006, Australia., Lu Y; Department of Genetics and Computational Biology, Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Queensland 4006, Australia., Amin N; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Karssen LC; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Sim KS; Division of Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore., van Leeuwen EM; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Iglesias AI; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Verhoeven VJ; 1] Department of Ophthalmology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [2] Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Hauser MA; Departments of Medicine and Ophthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA., Loon SC; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119077, Singapore., Despriet DD; Department of Ophthalmology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Nag A; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK., Venturini C; 1] Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK [2] UCL Institute of Ophthalmology, London EC1V 9EL, UK., Sanfilippo PG; Centre for Eye Research Australia (CERA), University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria 3002, Australia., Schillert A; Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck 23562, Germany., Kang JH; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA., Landers J; Department of Ophthalmology, Flinders University, Adelaide, South Australia 5042, Australia., Jonasson F; 1] Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland [2] Department of Ophthalmology, Landspitali National University Hospital, Reykjavik 101, Iceland., Cree AJ; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK., van Koolwijk LM; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Rivadeneira F; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [2] Department of Internal Medicine, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [3] Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague 2593 CE, The Netherlands., Souzeau E; Department of Ophthalmology, Flinders University, Adelaide, South Australia 5042, Australia., Jonsson V; Department of Ophthalmology, Landspitali National University Hospital, Reykjavik 101, Iceland., Menon G; Department of Ophthalmology, Frimley Park Hospital NHS Foundation Trust, Frimley GU16 7UJ, UK., Weinreb RN; Department of Ophthalmology and Hamilton Glaucoma Center, University of California, San Diego, California 92093, USA., de Jong PT; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [2] Department of Retinal Signal Processing, Netherlands Institute for Neuroscience, Amsterdam 1105 BA, The Netherlands [3] Department of Ophthalmology, Academic Medical Center, Amsterdam 1105 AZ, The Netherlands [4] Department of Ophthalmology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands., Oostra BA; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Uitterlinden AG; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [2] Department of Internal Medicine, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [3] Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague 2593 CE, The Netherlands., Hofman A; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague 2593 CE, The Netherlands., Ennis S; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK., Thorsteinsdottir U; 1] deCODE/Amgen, Reykjavik 101, Iceland [2] Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Burdon KP; Department of Ophthalmology, Flinders University, Adelaide, South Australia 5042, Australia., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK., Mirshahi A; Department of Ophthalmology, University Medical Center Mainz, Mainz 55131, Germany., Saw SM; 1] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119077, Singapore [2] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [3] Duke-National University of Singapore, Graduate Medical School, Singapore 169857, Singapore [4] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore., Vingerling JR; 1] Department of Ophthalmology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [2] Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Teo YY; 1] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore [2] Department of Statistics and Applied Probability, National University of Singapore, Singapore 119077, Singapore., Haines JL; 1] Department of Molecular Physiology and Biophysics, Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA [2] Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio 44106, USA., Wolfs RC; Department of Ophthalmology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Lemij HG; Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam 3011 BH, The Netherlands., Tai ES; 1] Duke-National University of Singapore, Graduate Medical School, Singapore 169857, Singapore [2] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore [3] Department of Medicine, National University of Singapore and National University Health System, Singapore 119077, Singapore., Jansonius NM; Department of Ophthalmology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., Jonas JB; 1] Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China [2] Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Seegartenklinik Heidelberg, Heidelberg 69117, Germany., Cheng CY; 1] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119077, Singapore [2] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [3] Duke-National University of Singapore, Graduate Medical School, Singapore 169857, Singapore., Aung T; 1] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119077, Singapore [2] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore., Viswanathan AC; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London EC1V 2PD, UK., Klaver CC; 1] Department of Ophthalmology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands [2] Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Craig JE; Department of Ophthalmology, Flinders University, Adelaide, South Australia 5042, Australia., Macgregor S; Department of Genetics and Computational Biology, Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Queensland 4006, Australia., Mackey DA; 1] Centre for Eye Research Australia (CERA), University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria 3002, Australia [2] Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia 6009, Australia., Lotery AJ; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK., Stefansson K; 1] deCODE/Amgen, Reykjavik 101, Iceland [2] Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Bergen AA; 1] Department of Clinical and Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam 1105 BA, the Netherlands [2] Department of Ophthalmology, Academic Medical Center, Amsterdam 1105 AZ, The Netherlands [3] Department of Clinical Genetics, Academic Medical Center, Amsterdam 1105 AZ, The Netherlands., Young TL; Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina 27710, USA., Wiggs JL; Department of Ophthalmology, Harvard Medical School and Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA., Pfeiffer N; Department of Ophthalmology, University Medical Center Mainz, Mainz 55131, Germany., Wong TY; 1] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119077, Singapore [2] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [3] Duke-National University of Singapore, Graduate Medical School, Singapore 169857, Singapore., Pasquale LR; 1] Department of Ophthalmology, Harvard Medical School and Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA [2] Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA., Hewitt AW; Centre for Eye Research Australia (CERA), University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria 3002, Australia., van Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands., Hammond CJ; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK.
Publikováno v:
Nature communications [Nat Commun] 2014 Sep 22; Vol. 5, pp. 4883. Date of Electronic Publication: 2014 Sep 22.
Autor:
Hoppenbrouwers IA; Department of Neurology, MS Centre ErasMS, Erasmus MC, Rotterdam, The Netherlands., Aulchenko YS, Janssens AC, Ramagopalan SV, Broer L, Kayser M, Ebers GC, Oostra BA, van Duijn CM, Hintzen RQ
Publikováno v:
Journal of human genetics [J Hum Genet] 2009 Nov; Vol. 54 (11), pp. 676-80. Date of Electronic Publication: 2009 Oct 16.