Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nielsen, Jonas B"'
Autor:
Akbari P; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Sosina OA; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Bovijn J; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Landheer K; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Nielsen JB; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Kim M; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Aykul S; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., De T; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Haas ME; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Hindy G; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Lin N; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Dinsmore IR; Department of Molecular and Functional Genomics, Geisinger Health System, Danville, PA, USA., Luo JZ; Department of Molecular and Functional Genomics, Geisinger Health System, Danville, PA, USA., Hectors S; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Geraghty B; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Germino M; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Panagis L; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Parasoglou P; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Walls JR; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Halasz G; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Atwal GS; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Jones M; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., LeBlanc MG; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Still CD; Geisinger Obesity Institute, Geisinger Health System, Danville, PA, USA., Carey DJ; Geisinger Obesity Institute, Geisinger Health System, Danville, PA, USA., Giontella A; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.; Department of Medicine, University of Verona, Verona, Italy., Orho-Melander M; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Berumen J; Unidad de Medicina Experimental de la Facultad de Medicina de la Universidad Nacional Autónoma de México, Mexico City, Mexico., Kuri-Morales P; Unidad de Medicina Experimental de la Facultad de Medicina de la Universidad Nacional Autónoma de México, Mexico City, Mexico.; Instituto Tecnológico y de Estudios Superiores de Monterrey, Monterrey, Mexico., Alegre-Díaz J; Unidad de Medicina Experimental de la Facultad de Medicina de la Universidad Nacional Autónoma de México, Mexico City, Mexico., Torres JM; MRC Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Clinical Trial Service Unit & Epidemiological Studies Unit Nuffield Department of Population Health, University of Oxford, Oxford, UK., Emberson JR; MRC Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Clinical Trial Service Unit & Epidemiological Studies Unit Nuffield Department of Population Health, University of Oxford, Oxford, UK., Collins R; Clinical Trial Service Unit & Epidemiological Studies Unit Nuffield Department of Population Health, University of Oxford, Oxford, UK., Rader DJ; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zambrowicz B; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Murphy AJ; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Balasubramanian S; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Overton JD; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Reid JG; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Shuldiner AR; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Cantor M; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Abecasis GR; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Ferreira MAR; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Sleeman MW; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Gusarova V; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Altarejos J; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Harris C; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Economides AN; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA.; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Idone V; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Karalis K; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Della Gatta G; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Mirshahi T; Geisinger Obesity Institute, Geisinger Health System, Danville, PA, USA., Yancopoulos GD; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Melander O; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.; Department of Emergency and Internal Medicine, Skåne University Hospital, Malmö, Sweden., Marchini J; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Tapia-Conyer R; Instituto Tecnológico y de Estudios Superiores de Monterrey, Monterrey, Mexico., Locke AE; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Baras A; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA. aris.baras@regeneron.com., Verweij N; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Lotta LA; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA. luca.lotta@regeneron.com.
Publikováno v:
Nature communications [Nat Commun] 2022 Aug 23; Vol. 13 (1), pp. 4844. Date of Electronic Publication: 2022 Aug 23.
Autor:
Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. wzhou@broadinstitute.org.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA. wzhou@broadinstitute.org.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. wzhou@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. wzhou@broadinstitute.org., Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Department of Thoracic Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Kabil O; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Division of Metabolism Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor, Michigan, USA., Gudmundsson J; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Thorleifsson G; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Weinstock J; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Zawistowski M; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Nielsen JB; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Epidemiology Research, Statens Serum Institute, Copenhagen, Denmark., Chaker L; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Medici M; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.; Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Radboud Institute for Molecular Life Sciences, 6500HB, Nijmegen, The Netherlands., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Naitza S; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy., Sanna S; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Schultheiss UT; Faculty of Medicine and Medical Center, Institute of Genetic Epidemiology, University of Freiburg, Freiburg, Germany.; Faculty of Medicine and Medical Center, Department of Medicine IV-Nephrology and Primary Care, University of Freiburg, Freiburg, Germany., Cappola A; Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA., Karjalainen J; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, 00014, Finland., Kurki M; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, 00014, Finland., Oneka M; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Taylor P; Thyroid Research Group, Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, UK., Fritsche LG; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Graham SE; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Wolford BN; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Overton W; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Rasheed H; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Haug EB; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Faculty of Medicine and Health Sciences, Department of Public Health and Nursing, Norwegian University of Science and Technology, NTNU, Trondheim, Norway., Skogholt AH; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Faculty of Medicine and Health Sciences, Department of Public Health and Nursing, Norwegian University of Science and Technology, NTNU, Trondheim, Norway., Surakka I; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Davey Smith G; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Pandit A; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Roychowdhury T; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Hornsby WE; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Jonasson JG; Landspitali-University Hospital, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland.; The Icelandic Cancer Registry, 105, Reykjavik, Iceland., Senter L; Division of Human Genetics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, 43210, USA., Liyanarachchi S; Department of Cancer Biology and Genetics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, 43210, USA., Ringel MD; Division of Endocrinology, Diabetes, and Metabolism, The Ohio State University, Columbus, Ohio, 43210, USA., Xu L; Department of Head and Neck Surgery, and Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA., Kiemeney LA; Radboud University Medical Centre, Radboud Institute for Health Sciences, 6500HB, Nijmegen, The Netherlands., He H; Department of Cancer Biology and Genetics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, 43210, USA., Netea-Maier RT; Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Radboud Institute for Molecular Life Sciences, 6500HB, Nijmegen, The Netherlands., Mayordomo JI; University of Colorado Hospital, Aurora, Colorado, 80045, USA., Plantinga TS; Department of Pathology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, 6500HB, Nijmegen, The Netherlands., Hrafnkelsson J; Landspitali-University Hospital, 101, Reykjavik, Iceland., Hjartarson H; Landspitali-University Hospital, 101, Reykjavik, Iceland., Sturgis EM; Department of Head and Neck Surgery, and Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA., Palotie A; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, 00014, Finland., Daly M; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, 00014, Finland., Citterio CE; Division of Metabolism Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Microbiología, Inmunología y Biotecnología/Cátedra de Genética, Buenos Aires, C1113AAD, Argentina.; CONICET-Universidad de Buenos Aires, Instituto de Inmunología, Genética y Metabolismo (INIGEM), C1120AAR, Buenos Aires, Argentina., Arvan P; Division of Metabolism Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor, Michigan, USA., Brummett CM; Division of Pain Medicine, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Boehnke M; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., de la Chapelle A; Department of Cancer Biology and Genetics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, 43210, USA., Stefansson K; deCODE genetics/AMGEN, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, 7600, Norway.; Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, 7600, Norway., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway. bjorn.o.asvold@ntnu.no.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, 7600, Norway. bjorn.o.asvold@ntnu.no.; Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. bjorn.o.asvold@ntnu.no.
Publikováno v:
Nature communications [Nat Commun] 2021 Dec 16; Vol. 12 (1), pp. 7354. Date of Electronic Publication: 2021 Dec 16.
Autor:
Nielsen JB; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA. jonas.bille.nielsen@gmail.com.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway. jonas.bille.nielsen@gmail.com., Rom O; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Surakka I; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Graham SE; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Zhou W; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Roychowdhury T; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Fritsche LG; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway.; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Gagliano Taliun SA; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Sidore C; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy., Liu Y; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway., Skogholt AH; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway., Wolford B; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Overton W; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Zhao Y; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Chen J; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Zhang H; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Hornsby WE; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Acheampong A; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Grooms A; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Schaefer A; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Zajac GJM; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Villacorta L; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Zhang J; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA., Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway., Løset M; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway.; Department of Dermatology, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Rai V; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Lundegaard PR; Laboratory for Molecular Cardiology, Department of Cardiology, Centre for Cardiac, Vascular, Pulmonary and Infectious Diseases, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Olesen MS; Laboratory for Molecular Cardiology, Department of Cardiology, Centre for Cardiac, Vascular, Pulmonary and Infectious Diseases, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Los Angeles Biomedical Research Institute, Harbor-UCLA, Torrance, CA, USA., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Chen YD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Los Angeles Biomedical Research Institute, Harbor-UCLA, Torrance, CA, USA., Choi SH; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Lubitz SA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Ellinor PT; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Barnes KC; Colorado Center for Personalized Medicine, School of Medicine, University of Colorado, Aurora, CO, USA., Daya M; Colorado Center for Personalized Medicine, School of Medicine, University of Colorado, Aurora, CO, USA., Rafaels N; Colorado Center for Personalized Medicine, School of Medicine, University of Colorado, Aurora, CO, USA., Weiss ST; Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Lasky-Su J; Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Tracy RP; Department of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Biochemistry, Larner College of Medicine, University of Vermont, Burlington, VT, USA., Vasan RS; Department of Medicine, Boston University School of Medicine, Boston, MA, 02118, USA.; Framingham Heart Study, Framingham, MA, USA., Cupples LA; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Mathias RA; GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Yanek LR; GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Becker LC; GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Aslibekyan S; The University of Alabama at Birmingham, Birmingham, AL, USA.; 23andMe, Inc., Sunnyvale, CA, USA., Hidalgo BA; The University of Alabama at Birmingham, Birmingham, AL, USA., Arnett DK; Deans Office, College of Public Health, University of Kentucky, Lexington, KY, USA., Irvin MR; The University of Alabama at Birmingham, Birmingham, AL, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA.; Jackson Heart Study, Jackson, MS, USA., Musani SK; Jackson Heart Study, Jackson, MS, USA.; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Correa A; Jackson Heart Study, Jackson, MS, USA.; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Los Angeles Biomedical Research Institute, Harbor-UCLA, Torrance, CA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Los Angeles Biomedical Research Institute, Harbor-UCLA, Torrance, CA, USA., Konkle BA; BloodWorks Northwest, University of Washington, Seattle, WA, USA., Johnsen JM; BloodWorks Northwest, University of Washington, Seattle, WA, USA., Ashley-Koch AE; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.; Department of Medicine, Duke University Medical Center, Durham, NC, USA., Telen MJ; Department of Medicine, Duke University Medical Center, Durham, NC, USA., Sheehan VA; Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA., Blangero J; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Curran JE; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Peralta JM; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Montgomery C; Department of Genes and Human Disease, Oklahoma Medical Research Foundation, Oklahoma, OK, USA., Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan., Chung RH; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan., Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Nouraie SM; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Gordeuk VR; University of Illinois at Chicago, Chicago, IL, USA., Zhang Y; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Jackson RD; Division of Endocrinology, Diabetes and Metabolism, Ohio State University, Columbus, OH, USA., Bleecker ER; Division of Pharmacogenomics University of Arizona, Tucson, AR, USA., Meyers DA; Division of Pharmacogenomics University of Arizona, Tucson, AR, USA., Li X; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AR, USA., Das S; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Yu K; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., LeFaive J; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Smith A; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Blackwell T; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Taliun D; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Zollner S; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Forer L; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AR, USA., Schoenherr S; Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Fuchsberger C; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Pandit A; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Zawistowski M; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Kheterpal S; Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA., Brummett CM; Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA., Natarajan P; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Schlessinger D; Laboratory of Genetics, National Institute on Aging, US National Institutes of Health, Baltimore, MD, USA., Lee S; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Kang HM; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Cucca F; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy.; Dipartimento di Scienze Biomediche, Università degli Studi di Sassari, Sassari, Italy., Holmen OL; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Levanger, Norway., Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Levanger, Norway.; Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Boehnke M; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Kathiresan S; Harvard Medical School, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute, Cambridge, MD, USA., Abecasis GR; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Chen YE; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA. echenum@umich.edu., Willer CJ; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA. cristen@umich.edu.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway. cristen@umich.edu.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. cristen@umich.edu.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA. cristen@umich.edu., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway. kristian.hveem@ntnu.no.; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Levanger, Norway. kristian.hveem@ntnu.no.; Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway. kristian.hveem@ntnu.no.
Publikováno v:
Nature communications [Nat Commun] 2020 Dec 18; Vol. 11 (1), pp. 6417. Date of Electronic Publication: 2020 Dec 18.
Autor:
Surakka I; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA., Fritsche LG; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA., Zhou W; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA, 02142, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Palmer Commons, 100 Washtenaw Avenue, Ann Arbor, MI, 48109, USA., Backman J; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA., Kosmicki JA; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA., Lu H; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA., Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Clinic of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Prinsesse Kristinas gate 3, 7030, Trondheim, Norway., Nielsen JB; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA., Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway., Skogholt AH; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway., Wolford B; Department of Computational Medicine and Bioinformatics, University of Michigan, Palmer Commons, 100 Washtenaw Avenue, Ann Arbor, MI, 48109, USA., Graham SE; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA., Chen YE; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA., Lee S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA., Kang HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA., Langhammer A; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway., Forsmo S; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway., Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway.; Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Prinsesse Kristinas gate 3, 7030, Trondheim, Norway., Styrkarsdottir U; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland., Holm H; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland., Gudbjartsson D; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Sturlugata 7, 101, Reykjavik, Iceland., Stefansson K; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Vatnsmýrarvegur 16, 101, Reykjavik, Iceland., Baras A; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA., Abecasis GR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA.; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway. kristian.hveem@ntnu.no.; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway. kristian.hveem@ntnu.no., Willer CJ; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA. cristen@umich.edu.; Department of Computational Medicine and Bioinformatics, University of Michigan, Palmer Commons, 100 Washtenaw Avenue, Ann Arbor, MI, 48109, USA. cristen@umich.edu.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway. cristen@umich.edu.; Department of Human Genetics, University of Michigan, 4909 Buhl Building, 1241 E. Catherine St, Ann Arbor, MI, 48109, USA. cristen@umich.edu.
Publikováno v:
Nature communications [Nat Commun] 2020 Oct 23; Vol. 11 (1), pp. 4093. Date of Electronic Publication: 2020 Oct 23.
Autor:
Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. wzhou@broadinstitute.org.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA. wzhou@broadinstitute.org.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. wzhou@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. wzhou@broadinstitute.org., Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Department of Thoracic Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Kabil O; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Division of Metabolism Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor, Michigan, USA., Gudmundsson J; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Thorleifsson G; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Weinstock J; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Zawistowski M; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Nielsen JB; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Epidemiology Research, Statens Serum Institute, Copenhagen, Denmark., Chaker L; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Medici M; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.; Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Radboud Institute for Molecular Life Sciences, 6500HB, Nijmegen, The Netherlands., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Naitza S; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy., Sanna S; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Schultheiss UT; Faculty of Medicine and Medical Center, Institute of Genetic Epidemiology, University of Freiburg, Freiburg, Germany.; Faculty of Medicine and Medical Center, Department of Medicine IV-Nephrology and Primary Care, University of Freiburg, Freiburg, Germany., Cappola A; Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA., Karjalainen J; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, 00014, Finland., Kurki M; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, 00014, Finland., Oneka M; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Taylor P; Thyroid Research Group, Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, UK., Fritsche LG; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Graham SE; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Wolford BN; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Overton W; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Rasheed H; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Haug EB; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Faculty of Medicine and Health Sciences, Department of Public Health and Nursing, Norwegian University of Science and Technology, NTNU, Trondheim, Norway., Skogholt AH; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Faculty of Medicine and Health Sciences, Department of Public Health and Nursing, Norwegian University of Science and Technology, NTNU, Trondheim, Norway., Surakka I; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Davey Smith G; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Pandit A; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Roychowdhury T; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Hornsby WE; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Jonasson JG; Landspitali-University Hospital, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland.; The Icelandic Cancer Registry, 105, Reykjavik, Iceland., Senter L; Division of Human Genetics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, 43210, USA., Liyanarachchi S; Department of Cancer Biology and Genetics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, 43210, USA., Ringel MD; Division of Endocrinology, Diabetes, and Metabolism, The Ohio State University, Columbus, Ohio, 43210, USA., Xu L; Department of Head and Neck Surgery, and Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA., Kiemeney LA; Radboud University Medical Centre, Radboud Institute for Health Sciences, 6500HB, Nijmegen, The Netherlands., He H; Department of Cancer Biology and Genetics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, 43210, USA., Netea-Maier RT; Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Radboud Institute for Molecular Life Sciences, 6500HB, Nijmegen, The Netherlands., Mayordomo JI; University of Colorado Hospital, Aurora, Colorado, 80045, USA., Plantinga TS; Department of Pathology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, 6500HB, Nijmegen, The Netherlands., Hrafnkelsson J; Landspitali-University Hospital, 101, Reykjavik, Iceland., Hjartarson H; Landspitali-University Hospital, 101, Reykjavik, Iceland., Sturgis EM; Department of Head and Neck Surgery, and Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA., Palotie A; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, 00014, Finland., Daly M; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, 00014, Finland., Citterio CE; Division of Metabolism Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Microbiología, Inmunología y Biotecnología/Cátedra de Genética, Buenos Aires, C1113AAD, Argentina.; CONICET-Universidad de Buenos Aires, Instituto de Inmunología, Genética y Metabolismo (INIGEM), C1120AAR, Buenos Aires, Argentina., Arvan P; Division of Metabolism Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor, Michigan, USA., Brummett CM; Division of Pain Medicine, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Boehnke M; Center for Statistical Genetics and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., de la Chapelle A; Department of Cancer Biology and Genetics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, 43210, USA., Stefansson K; deCODE genetics/AMGEN, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, 7600, Norway.; Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, 7600, Norway., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway. bjorn.o.asvold@ntnu.no.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, 7600, Norway. bjorn.o.asvold@ntnu.no.; Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. bjorn.o.asvold@ntnu.no.
Publikováno v:
Nature communications [Nat Commun] 2020 Aug 07; Vol. 11 (1), pp. 3981. Date of Electronic Publication: 2020 Aug 07.
Autor:
Wang H; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Lane JM; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Jones SE; Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom., Dashti HS; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Ollila HM; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom., van Hees VT; Netherlands eScience Center, Amsterdam, Netherlands., Brumpton B; K.G. Jebsen Centre for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Department of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Winsvold BS; K.G. Jebsen Centre for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.; Division of Clinical Neuroscience, Oslo University Hospital and University of Oslo, Oslo, Norway., Kantojärvi K; Genomics and Biomarkers Unit, National Institute for Health and Welfare, Helsinki, Finland.; Department of Psychiatry and SleepWell Research Program, Faculty of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Palviainen T; Institute for Molecular Medicine FIMM, HiLIFE, University of Helsinki, Helsinki, Finland., Cade BE; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Sofer T; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Song Y; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Northeastern University College of Science, Boston, MA, USA., Patel K; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Northeastern University College of Science, Boston, MA, USA., Anderson SG; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The George Alleyne Chronic Disease Research Centre, Caribbean Institute for Health Research, University of the West Indies, Cave Hill, Barbados., Bechtold DA; Division of Endocrinology, Diabetes & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Bowden J; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Emsley R; Division of Endocrinology, Diabetes & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Kyle SD; Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Little MA; Department of Mathematics, Aston University, Birmingham, UK.; Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA., Loudon AS; Division of Endocrinology, Diabetes & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Scheer FAJL; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Purcell SM; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Richmond RC; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; School of Social and Community Medicine, University of Bristol, Bristol, UK., Spiegelhalder K; Clinic for Psychiatry and Psychotherapy, Medical Centre, University of Freiburg, Freiburg, Germany., Tyrrell J; Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom., Zhu X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Hublin C; Institute for Molecular Medicine FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Kaprio JA; Institute for Molecular Medicine FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Kristiansson K; Genomics and Biomarkers Unit, National Institute for Health and Welfare, Helsinki, Finland., Sulkava S; Genomics and Biomarkers Unit, National Institute for Health and Welfare, Helsinki, Finland.; Department of Psychiatry and SleepWell Research Program, Faculty of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Paunio T; Genomics and Biomarkers Unit, National Institute for Health and Welfare, Helsinki, Finland.; Department of Psychiatry and SleepWell Research Program, Faculty of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Hveem K; K.G. Jebsen Centre for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK., Nielsen JB; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, USA., Willer CJ; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, USA., Zwart JA; Division of Clinical Neuroscience, Oslo University Hospital and University of Oslo, Oslo, Norway., Strand LB; K.G. Jebsen Centre for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom., Ray D; NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, OX39DU, UK., Lawlor DA; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Rutter MK; Division of Endocrinology, Diabetes & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Manchester Diabetes Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Weedon MN; Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom., Redline S; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Saxena R; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. rsaxena@partners.org.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA. rsaxena@partners.org.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. rsaxena@partners.org.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. rsaxena@partners.org.
Publikováno v:
Nature communications [Nat Commun] 2019 Aug 13; Vol. 10 (1), pp. 3503. Date of Electronic Publication: 2019 Aug 13.
Autor:
Graham SE; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, 48109, MI, USA., Nielsen JB; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, 48109, MI, USA., Zawistowski M; Department of Biostatistics: Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, 48109, MI, USA., Fritsche LG; Department of Biostatistics: Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 7491, Norway.; Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 7491, Norway., Skogholt AH; K.G. Jebsen Center for Genetic Epidemiology, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 7491, Norway.; Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 7491, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 7491, Norway., Surakka I; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, 48109, MI, USA., Hornsby WE; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, 48109, MI, USA., Fermin D; Department of Pediatrics: Pediatric Nephrology, University of Michigan, Ann Arbor, 48109, MI, USA., Larach DB; Department of Anesthesiology, University of Michigan, Ann Arbor, 48109, MI, USA., Kheterpal S; Department of Anesthesiology, University of Michigan, Ann Arbor, 48109, MI, USA., Brummett CM; Department of Anesthesiology, University of Michigan, Ann Arbor, 48109, MI, USA., Lee S; Department of Biostatistics: Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Kang HM; Department of Biostatistics: Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Abecasis GR; Department of Biostatistics: Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Romundstad S; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 7491, Norway.; Department of Internal Medicine, Levanger Hospital, Health Trust Nord-Trøndelag, Levanger, 7600, Norway., Hallan S; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 7491, Norway.; Department of Nephrology, St Olav Hospital, Trondheim, 7491, Norway., Sampson MG; Department of Pediatrics: Pediatric Nephrology, University of Michigan, Ann Arbor, 48109, MI, USA., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 7491, Norway. kristian.hveem@ntnu.no.; Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 7491, Norway. kristian.hveem@ntnu.no.; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, 7600, Norway. kristian.hveem@ntnu.no., Willer CJ; Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, 48109, MI, USA. cristen@umich.edu.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, 48109, MI, USA. cristen@umich.edu.; Department of Human Genetics, University of Michigan, Ann Arbor, 48109, MI, USA. cristen@umich.edu.
Publikováno v:
Nature communications [Nat Commun] 2019 Apr 23; Vol. 10 (1), pp. 1847. Date of Electronic Publication: 2019 Apr 23.
Autor:
Ahlberg G; Laboratory for Molecular Cardiology, Department of Cardiology, The Heart Centre, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, 2100 Ø, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark., Refsgaard L; Laboratory for Molecular Cardiology, Department of Cardiology, The Heart Centre, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, 2100 Ø, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark., Lundegaard PR; Laboratory for Molecular Cardiology, Department of Cardiology, The Heart Centre, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, 2100 Ø, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark., Andreasen L; Laboratory for Molecular Cardiology, Department of Cardiology, The Heart Centre, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, 2100 Ø, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark., Ranthe MF; Department of Epidemiology Research, Statens Serum Institute, Copenhagen, 2300 S, Denmark., Linscheid N; Cardiac Proteomics Group, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark.; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark., Nielsen JB; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark., Melbye M; Department of Epidemiology Research, Statens Serum Institute, Copenhagen, 2300 S, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark.; Department of Medicine, Stanford University School of Medicine, Stanford, 94305, CA, USA., Haunsø S; Laboratory for Molecular Cardiology, Department of Cardiology, The Heart Centre, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, 2100 Ø, Denmark., Sajadieh A; Department of Cardiology, Copenhagen University Hospital, Bispebjerg, Copenhagen, 2400, Denmark., Camp L; The Lundbeck Foundation Centre for Applied Medical Genomics in Personalized Disease Prediction, Prevention and Care, Copenhagen, 2200 N, Denmark., Olesen SP; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark., Rasmussen S; Department of Bio and Health Informatics, Technical University of Denmark, Kgs, Lyngby, 2800, Denmark., Lundby A; Cardiac Proteomics Group, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark.; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark., Ellinor PT; Cardiovascular Research Centre, Massachusetts General Hospital, Boston, 02114, MA, USA.; Program in Population and Medical Genetics, The Broad Institute of Harvard and MIT, Cambridge, 02114, MA, USA., Holst AG; Laboratory for Molecular Cardiology, Department of Cardiology, The Heart Centre, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, 2100 Ø, Denmark., Svendsen JH; Laboratory for Molecular Cardiology, Department of Cardiology, The Heart Centre, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, 2100 Ø, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark., Olesen MS; Laboratory for Molecular Cardiology, Department of Cardiology, The Heart Centre, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, 2100 Ø, Denmark. mortensol@sund.ku.dk.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, 2200 N, Denmark. mortensol@sund.ku.dk.
Publikováno v:
Nature communications [Nat Commun] 2018 Oct 17; Vol. 9 (1), pp. 4316. Date of Electronic Publication: 2018 Oct 17.
Autor:
Gusarova V; Regeneron Pharmaceuticals, Tarrytown, 10591, NY, USA., O'Dushlaine C; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Teslovich TM; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Benotti PN; Geisinger, Danville, 17822, PA, USA., Mirshahi T; Geisinger, Danville, 17822, PA, USA., Gottesman O; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Van Hout CV; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Murray MF; Geisinger, Danville, 17822, PA, USA., Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Nielsen JB; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, University of Michigan, Ann Arbor, 48109, MI, USA.; Department of Human Genetics, University of Michigan, University of Michigan, Ann Arbor, 48109, MI, USA., Fritsche L; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Wulff AB; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, 2100, Denmark., Gudbjartsson DF; deCODE Genetics/Amgen, Inc., Reykjavik, 101, Iceland., Sjögren M; Department of Clinical Sciences, Malmö, Lund University, Malmö, 221, Sweden., Emdin CA; Program in Medical and Population Genetics, Broad Institute, Cambridge, 02142, MA, USA., Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.; Department of Social Work, Tunghai University, Taichung, 40704, Taiwan., Small A; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, PA, USA.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, USA., Kwee LC; Division of Cardiology, Department of Medicine; Molecular Physiology Institute, School of Medicine, Duke University, Durham, 27710, NC, USA., Dwivedi OP; Finnish Institute of Molecular Medicine (FIMM), Helsinki University, Helsinki, 00170, Finland., Prasad RB; Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, 221, Sweden., Bruse S; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Lopez AE; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Penn J; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Marcketta A; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Leader JB; Geisinger, Danville, 17822, PA, USA., Still CD; Geisinger, Danville, 17822, PA, USA., Kirchner HL; Geisinger, Danville, 17822, PA, USA., Mirshahi UL; Geisinger, Danville, 17822, PA, USA., Wardeh AH; Geisinger, Danville, 17822, PA, USA., Hartle CM; Geisinger, Danville, 17822, PA, USA., Habegger L; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Fetterolf SN; Geisinger, Danville, 17822, PA, USA., Tusie-Luna T; Instituto de Investigaciones Biomédicas, UNAM, Coyoacán, 04510, Mexico City, Mexico.; Unidad de Biología Molecular y Medicina Genómica, UNAM/INCMNSZ Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, 14080, Mexico., Morris AP; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Department of Biostatistics, University of Liverpool, Liverpool, L69 7ZX, UK.; Estonian Genome Center, University of Tartu, Tartu, 50090, Estonia., Holm H; deCODE Genetics/Amgen, Inc., Reykjavik, 101, Iceland., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, 101, Iceland., Sulem P; deCODE Genetics/Amgen, Inc., Reykjavik, 101, Iceland., Thorsteinsdottir U; deCODE Genetics/Amgen, Inc., Reykjavik, 101, Iceland., Rotter JI; Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Chuang LM; Division of Endocrinology & Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, 10617, Taiwan.; Institute of Preventive Medicine, School of Public Health, National Taiwan University, Taipei, 10617, Taiwan., Damrauer S; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, PA, USA.; Department of Surgery, Corporal Michael Crescenz VA Medical Center, Philadelphia, 19104, PA, USA., Birtwell D; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, PA, USA.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, USA., Brummett CM; Department of Anesthesiology, University of Michigan, Ann Arbor, 48109, MI, USA., Khera AV; Program in Medical and Population Genetics, Broad Institute, Cambridge, 02142, MA, USA.; Center for Human Genetic Research, Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, MA, USA., Natarajan P; Program in Medical and Population Genetics, Broad Institute, Cambridge, 02142, MA, USA.; Center for Human Genetic Research, Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, MA, USA., Orho-Melander M; Department of Clinical Sciences, Malmö, Lund University, Malmö, 221, Sweden., Flannick J; Program in Medical and Population Genetics, Broad Institute, Cambridge, 02142, MA, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, MA, USA., Lotta LA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, University of Michigan, Ann Arbor, 48109, MI, USA.; Department of Human Genetics, University of Michigan, University of Michigan, Ann Arbor, 48109, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, 48109, MI, USA., Holmen OL; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, 7601, Norway., Ritchie MD; Geisinger, Danville, 17822, PA, USA., Ledbetter DH; Geisinger, Danville, 17822, PA, USA., Murphy AJ; Regeneron Pharmaceuticals, Tarrytown, 10591, NY, USA., Borecki IB; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Reid JG; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Overton JD; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Hansson O; Finnish Institute of Molecular Medicine (FIMM), Helsinki University, Helsinki, 00170, Finland.; Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, 221, Sweden., Groop L; Finnish Institute of Molecular Medicine (FIMM), Helsinki University, Helsinki, 00170, Finland.; Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, 221, Sweden., Shah SH; Division of Cardiology, Department of Medicine; Molecular Physiology Institute, School of Medicine, Duke University, Durham, 27710, NC, USA., Kraus WE; Division of Cardiology, Department of Medicine; Molecular Physiology Institute, School of Medicine, Duke University, Durham, 27710, NC, USA., Rader DJ; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, PA, USA.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, USA., Chen YI; Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, 7601, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, 7491, Norway.; Department of Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, 7601, Norway., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK., Kathiresan S; Center for Human Genetic Research, Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, MA, USA., Melander O; Department of Clinical Sciences, Malmö, Lund University, Malmö, 221, Sweden., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, 101, Iceland., Nordestgaard BG; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, 2730, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, 2730, Denmark.; The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen, 2400, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark., Tybjærg-Hansen A; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, 2100, Denmark.; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, 2730, Denmark.; The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen, 2400, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark., Abecasis GR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Altshuler D; Program in Medical and Population Genetics, Broad Institute, Cambridge, 02142, MA, USA.; Department of Molecular Biology, Diabetes Unit, and Center for Human Genetic Research, Massachusetts General Hospital, Boston, 02114, MA, USA.; Departments of Genetics and Medicine, Harvard Medical School, Boston, 02115, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, 02139, MA, USA., Florez JC; Diabetes Unit and Center for Human Genetic Research, Massachusetts General Hospital, Boston, 02115, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, 02142, MA, USA.; Department of Medicine, Harvard Medical School, Boston, 02115, MA, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., McCarthy MI; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, OX3 7LE, UK.; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, OX4 2PG, UK., Yancopoulos GD; Regeneron Pharmaceuticals, Tarrytown, 10591, NY, USA., Carey DJ; Geisinger, Danville, 17822, PA, USA., Shuldiner AR; Regeneron Genetics Center, Tarrytown, 10591, NY, USA., Baras A; Regeneron Genetics Center, Tarrytown, 10591, NY, USA. aris.baras@regeneron.com., Dewey FE; Regeneron Genetics Center, Tarrytown, 10591, NY, USA. rickdewey@gmail.com., Gromada J; Regeneron Pharmaceuticals, Tarrytown, 10591, NY, USA. jesper.gromada@regeneron.com.
Publikováno v:
Nature communications [Nat Commun] 2018 Jun 13; Vol. 9 (1), pp. 2252. Date of Electronic Publication: 2018 Jun 13.
Autor:
Helgadottir A; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland. anna.helgadottir@decode.is., Thorleifsson G; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland., Gretarsdottir S; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland., Stefansson OA; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland., Tragante V; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland., Thorolfsdottir RB; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland., Jonsdottir I; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Bjornsson T; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland., Steinthorsdottir V; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, 9700 RB, Groningen, The Netherlands.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Nielsen JB; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, 48109, MI, USA., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, 48109, MI, USA., Folkersen L; Cardiovascular Medicine Unit, Department of Medicine, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, 17176, Sweden.; Department of Bioinformatics, Technical University of Denmark, Copenhagen, 2800, Denmark., Martinsson A; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, 22185, Sweden., Heydarpour M; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA., Prakash S; Department of Internal Medicine, Division of Medical Genetics, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Oskarsson G; Childrens Hospital, Landspitali National University Hospital of Iceland, Reykjavik, 101, Iceland., Gudbjartsson T; Department of Surgery and Cardiothoracic Surgery, Landspitali National University Hospital, Reykjavik, 101, Iceland., Geirsson A; Section of Cardiac Surgery, Department of Surgery, Yale University School of Medicine, New Haven, 06510, CT, USA., Olafsson I; Department of Clinical Biochemistry, Landspitali National University Hospital, Reykjavik, 101, Iceland., Sigurdsson EL; Heilsugaeslan Solvangi, Hafnarfjördur, 220, Iceland.; Department of Family Medicine, University of Iceland, Reykjavik, 101, Iceland., Almgren P; Department of Clinical Sciences, Lund University, Malmö, 22185, Sweden.; Department of Internal Medicine, Skåne University Hospital, Malmö, 22185, Sweden., Melander O; Department of Clinical Sciences, Lund University, Malmö, 22185, Sweden.; Department of Internal Medicine, Skåne University Hospital, Malmö, 22185, Sweden., Franco-Cereceda A; Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, 17176, Sweden., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, 17176, Sweden., Fritsche L; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, 7491, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, 7491, Norway., Lin M; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, 48109, MI, USA., Yang B; Department of Cardiac Surgery, University of Michigan, Ann Arbor, MI, 48105, USA.; Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, 48109, USA., Hornsby W; Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, 48109, USA., Guo D; Department of Internal Medicine, Division of Medical Genetics, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Brummett CM; Department of Anesthesiology, University of Michigan, Ann Arbor, MI, 48105, USA., Abecasis G; Department of Biostatistics, University of Michigan, Ann Arbor, MI, 48109, USA., Mathis M; Department of Anesthesiology, University of Michigan, Ann Arbor, MI, 48105, USA., Milewicz D; Department of Internal Medicine, Division of Medical Genetics, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA.; Medicine Services, Texas Heart Institute, St. Luke's Episcopal Hospital, Houston, TX, 77030, USA., Body SC; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA., Eriksson P; Cardiovascular Medicine Unit, Department of Medicine, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, 17176, Sweden., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, 48109, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, 48109, MI, USA.; Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, 7491, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, 7491, Norway., Newton-Cheh C; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.; Massachusetts General Hospital, Harvard Medical School, Broad Institute of Harvard and MIT, Boston, MA, 02114, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, 02114, USA., Smith JG; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, 22185, Sweden., Danielsen R; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; Department of Internal Medicine, Division of Cardiology, Landspitali National University Hospital of Iceland, Reykjavik, 101, Iceland., Thorgeirsson G; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; Department of Internal Medicine, Division of Cardiology, Landspitali National University Hospital of Iceland, Reykjavik, 101, Iceland., Thorsteinsdottir U; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Gudbjartsson DF; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, 101, Iceland., Holm H; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland., Stefansson K; deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland. kstefans@decode.is.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland. kstefans@decode.is.
Publikováno v:
Nature communications [Nat Commun] 2018 Mar 07; Vol. 9 (1), pp. 987. Date of Electronic Publication: 2018 Mar 07.