Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Uk Lee"'
Autor:
Ng AWT; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., McClurg DP; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Wesley B; Irving Institute for Cancer Dynamics, Columbia University, New York, USA., Zamani SA; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Black E; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Miremadi A; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Giger O; Department of Pathology, University of Cambridge, Cambridge, CB2 0QQ, UK., Hoopen RT; Department of Oncology, University of Cambridge, Cambridge, CB2 0QQ, UK., Devonshire G; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Redmond AM; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Grehan N; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Jammula S; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Blasko A; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Li X; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Aparicio S; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Tavaré S; Irving Institute for Cancer Dynamics, Columbia University, New York, USA.; Department of Statistics, Columbia University, New York, USA.; Department of Biological Sciences, Columbia University, New York, USA., Nowicki-Osuch K; Irving Institute for Cancer Dynamics, Columbia University, New York, USA., Fitzgerald RC; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK. rcf29@cam.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2024 May 28; Vol. 15 (1), pp. 4533. Date of Electronic Publication: 2024 May 28.
Autor:
Ng AWT; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., McClurg DP; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Wesley B; Irving Institute for Cancer Dynamics, Columbia University, New York, USA., Zamani SA; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Black E; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Miremadi A; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Giger O; Department of Pathology, University of Cambridge, Cambridge, CB2 0QQ, UK., Hoopen RT; Department of Oncology, University of Cambridge, Cambridge, CB2 0QQ, UK., Devonshire G; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Redmond AM; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Grehan N; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Jammula S; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Blasko A; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Li X; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Aparicio S; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Tavaré S; Irving Institute for Cancer Dynamics, Columbia University, New York, USA.; Department of Statistics, Columbia University, New York, USA.; Department of Biological Sciences, Columbia University, New York, USA., Nowicki-Osuch K; Irving Institute for Cancer Dynamics, Columbia University, New York, USA., Fitzgerald RC; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK. rcf29@cam.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2024 May 14; Vol. 15 (1), pp. 4074. Date of Electronic Publication: 2024 May 14.
Autor:
van de Vegte YJ; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, 9700RB, the Netherlands., Eppinga RN; Department of Cardiology, Isala Zwolle ziekenhuis, Zwolle, 8025 AB, the Netherlands., van der Ende MY; Department of Cardiology, University medical Center Utrecht, Utrecht, 3584 Cx, the Netherlands., Hagemeijer YP; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, 9700RB, the Netherlands.; Analytical Biochemistry, University of Groningen, Groningen, 9713 AV, the Netherlands., Mahendran Y; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medicine Science, University of Copenhagen, Copenhagen Ø, 2100, Denmark., Salfati E; Department of Medicine, Stanford University School of Medicine, Stanford, 94305, USA.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Smith AV; Department of Biostatistics, University of Michigan, Ann Arbor, MI48109, USA., Tan VY; Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, BS82BN, UK.; MRC Integrative Epidemiology, University of Bristol, Bristol, BS82BN, UK., Arking DE; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, 21215, USA., Ntalla I; Clinical Pharmacology and Precision Medicine, William Harvey Research Institute, Barts and The London Faculty of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Appel EV; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medicine Science, University of Copenhagen, Copenhagen Ø, 2100, Denmark., Schurmann C; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, 10029, USA., Brody JA; Medicine, University of Washington, Seattle, 98195, USA., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, 1015, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., Polasek O; Department of Public Health, University of Split School of Medicine, Split, 21000, Croatia.; Algebra LAB, Algebra University College, Zagreb, 10000, Croatia., Sveinbjornsson G; deCODE genetics / Amgen Inc., Reykjavik, 102, Iceland., Lecoeur C; UMR 8199, University of Lille Nord de France, Lille, 59000, France., Ladenvall C; Clinial Genomics Uppsala, Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, 75185, Sweden.; Lund University Diabetes Center, Department of Clinical Sciences, Lund University, Malmö, 20502, Sweden., Zhao JH; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, Victor Phillip Dahdaleh Heart & Lung Research Institute, University of Cambridge, Cambridge, CB2 0BB, UK., Isaacs A; CARIM School for Cardiovascular Diseases, Maastricht Centre for Systems Biology (MaCSBio), Department of Physiology, Maastricht University, Maastricht, 6229ER, Netherlands., Wang L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, 63108-2212, Campus Box 8506, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Hwang SJ; Division of Intramural Research, National Heart Lung and Blood Institute, NIH, USA, Framingham, 1702, USA., Mononen N; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, FI-33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, FI-33014, Finland., Auro K; Department of Health, unit of genetics and biomarkers, , National Institute for Health and Welfare, Finland, Helsinki, FI-00290, Finland.; Department of molecular medicine, University of Helsinki, Helsinki, FI-00290, Finland., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Bielak LF; Department of Epidemiology, University of Michigan, Ann Arbor, MI, 48109, USA., Zeng L; Department of Cardiology, Deutsches Herzzentrum München, Technische Universität München, Munich, 80636, Germany., Shah N; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, DD1 9SY, UK.; Pharmacogenetics Research Lab, Department of Pharmacy, COMSATS University Islamabad, Abbottabad, 22060, Pakistan., Nethander M; Sahlgrenska Osteoporosis Centre, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 41345, Sweden.; Bioinformatics Core Facility, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, EH16 4UX, UK., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, 70808, USA., Pechlivanis S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, 45122, Germany., Qi L; Department of Epidemiology, Tulane University, New Orleans, LA, 70112, USA., Zhao W; Department of Epidemiology, University of Michigan, Ann Arbor, MI, 48109, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Rizzi F; Unit of Biomedicine, Bio4Dreams-Business Nursery for Life Sciences, Milano, 20121, Italy., Tanaka T; Longitudinal Study Section, National Institute on Aging, Baltimore, 21224, USA., Robino A; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Cocca M; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Lange L; Medicine, University of Colorado Anschutz Medical Campus, Aurora, 80045, USA., Müller-Nurasyid M; IBE, Ludwig-Maximilians-University Munich, LMU Munich, Munich, 81377, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, 55101, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Roselli C; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, 02142, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UB1 3HW, UK., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, 68167, Germany.; SYNLAB MVZ Humangenetik Mannheim, Mannheim, 68163, Germany., Guo X; Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA, Torrance, 90502, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, 90502, USA., Lin HJ; Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA, Torrance, 90502, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, 90502, USA., Pavani F; Institute for Biomedicine, Eurac Research, Bolzano, 39100, Italy., Galesloot TE; Radboud university medical center, Nijmegen, 6500 HB, the Netherlands., Noordam R; Department of Internal Medicine, section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, 2300 RC, the Netherlands., Milaneschi Y; Department of Psychiatry, Amsterdam Public Health, Amsterdam UMC, Amsterdam UMC, Vrije Universiteit, Amsterdam, Amsterdam, 1081 HL, the Netherlands., Schraut KE; Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, Scotland, UK., den Hoed M; The Beijer laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Uppsala, 75237, Sweden., Degenhardt F; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, 24105, Germany., Trompet S; Department of Internal Medicine, section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, 2300 RC, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, ZA, 2333, the Netherlands., van den Berg ME; Department of Epidemiology, Erasmus Medical Center, Rotterdam, 3015GD, the Netherlands., Pistis G; Institute of Genetics and Biomedic Research (IRGB), Italian National Research Council (CNR), Monserrato, (CA), 9042, Italy.; Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, USA., Tham YC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, 17475, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, 17475, Germany., Sim XS; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Li HL; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, FI-33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, FI-33014, Finland.; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB2 0SL, UK., Said MA; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, 9700RB, the Netherlands., Witte DR; Department of Public Health, Aarhus University, Aarhus C, 8000, Denmark., Iribarren C; Division of Research, Kaiser Permenente of Northern California, Oakland, 94612, USA.; The Scripps Research Institute, La Jolla, 10550, USA., Launer L; National Institute on Aging, Bethesda, MSC2292, USA., Ring SM; Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, BS82BN, UK.; MRC Integrative Epidemiology, University of Bristol, Bristol, BS82BN, UK., de Vries PS; Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center at Houston, School of Public Health, Houston, 77030, USA., Sever P; National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, 2400, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, 10029, USA.; Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, 10029, USA., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, G12 8TA, UK., Psaty BM; Departments of Medicine, Epidemiology and Health Systems and Population Health, University of Washington, Seattle, 98195, USA., Sotoodehnia N; Medicine and Epidemiology, University of Washington, Seattle, 98195, USA., Kolcic I; Department of Public Health, University of Split School of Medicine, Split, 21000, Croatia.; Algebra LAB, Algebra University College, Zagreb, 10000, Croatia., Arnar DO; deCODE genetics / Amgen Inc., Reykjavik, 102, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, 101, Iceland.; Department of Medicine, Landspitali-The National University Hospital of Iceland, Reykjavik, 101, Iceland., Gudbjartsson DF; deCODE genetics / Amgen Inc., Reykjavik, 102, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, 101, Iceland., Holm H; deCODE genetics / Amgen Inc., Reykjavik, 102, Iceland., Balkau B; Centre for Research in Epidemiology and Population Health, Institut national de la santé et de la recherche médicale, Villejuif, 94800, France.; UMRS 1018, University Versailles Saint-Quentin-en-Yvelines, Versailles, 78035, France.; UMRS 1018, University Paris Sud, Villejuif, 94807, France., Silva CT; Genetic Epidemiology Unit, Dept. of Epidemiology, Erasmus University Medical Center, Rotterdam, 3000CA, Netherlands., Newton-Cheh CH; Cardiology Section, Massachusetts general hospital,, Boston, 02130, USA., Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, FI-33521, Finland.; Department of Cardiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, FI-33014, Finland., Salo P; Department of Health, unit of genetics and biomarkers, , National Institute for Health and Welfare, Finland, Helsinki, FI-00290, Finland.; Department of molecular medicine, University of Helsinki, Helsinki, FI-00290, Finland., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Peyser PA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, 48109, USA., Schunkert H; Department of Cardiology, Deutsches Herzzentrum München, Technische Universität München, Munich, 80636, Germany.; Deutsches Zentrum für Herz- und Kreislauferkrankungen (DZHK), Partner Site Munich Heart Alliance, Munich, 80636, Germany., Lorentzon M; Sahlgrenska Osteoporosis Centre, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 41345, Sweden.; Region Västra Götaland, Geriatric Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Mölndal, 43180, Sweden.; Mary McKillop Institute for Health Research, Australian Catholic University, Melbourne, 3000, Australia., Lahti J; Department of Psychology and Logopedics, University of Helsinki, Helsinki, 00014, Finland., Rao DC; Division of Biostatistics, Washington University, St. Louis, MO, 63110, USA., Cornelis MC; Preventive Medicine, Northwestern University, Chicago, IL, 60611, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, 48109, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Stolarz-Skrzypek K; Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, 31-008, Poland., Bandinelli S; Geriatric Unit, Unità sanitaria locale Toscana Centro, Florence, 50142, Italy., Concas MP; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Sinagra G; Cardiovascular Department, 'Ospedali Riuniti and University of Trieste', Trieste, 34149, Italy., Meitinger T; Institute of Human Genetics, Klinikum rechts der Isar, Technische Universität München, München, 81675, Germany.; Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Waldenberger M; Research Unit Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; German Centre for Cardiovascular Research (DZHK), partner site: Munich Heart Alliance, Munich, 80802, Germany., Sinner MF; German Centre for Cardiovascular Research (DZHK), partner site: Munich Heart Alliance, Munich, 80802, Germany.; Department of Cardiology, University Hospital, LMU Munich, Munich, 81377, Germany., Strauch K; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, 55101, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, 81377, Germany., Delgado GE; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, 68167, Germany., Taylor KD; Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA, Torrance, 90502, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, 90502, USA., Yao J; Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA, Torrance, 90502, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, 90502, USA., Foco L; Institute for Biomedicine, Eurac Research, Bolzano, 39100, Italy., Melander O; Department of Internal Medicine, Clinical Sciences, Lund University and Skåne University Hospital, Malmo, 221 85, Sweden.; Lund University Diabetes Center, Lund University, Malmö, 221 85, Sweden., de Graaf J; Radboud university medical center, Nijmegen, 6500 HB, the Netherlands., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2300 RC, the Netherlands., de Geus EJC; Biological Psychology, EMGO+ Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University, Amsterdam, 1081 BT, the Netherlands., Johansson Å; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, 75108, Sweden., Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland, UK., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University Hospital, Uppsala, 75237, Sweden., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, 24105, Germany., Macfarlane PW; Institute of Health and Wellbeing, Faculty of Medicine, University of Glasgow, Glasgow, G12 0XH, UK., Tarasov KV; Laboratory of Cardiovascular Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Tan N; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore., Felix SB; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, 17475, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17475, Germany., Tai ES; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., Quek DQ; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Ormel J; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Ingelsson M; Department of Public Health and Caring Sciences, Molecular Geriatrics, Uppsala University, Uppsala, 75237, Sweden., Lindgren C; Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Morris AP; Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Raitakari OT; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, FI-20521, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, FI-20521, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, FI-20521, Finland., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medicine Science, University of Copenhagen, Copenhagen Ø, 2100, Denmark., Assimes T; Department of Medicine, Stanford University School of Medicine, Stanford, 94305, USA., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; Icelandic Heart Association, Kopavogur, 201, Iceland., Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School,, University of Bristol, Bristol, BS8 2BN, UK., Morrison AC; Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center at Houston, School of Public Health, Houston, 77030, USA., Munroe PB; Clinical Pharmacology and Precision Medicine, William Harvey Research Institute, Barts and The London Faculty of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Biomedical Research Centre, Barts and The London Faculty of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Strachan DP; Population Health Research Institute, St George's, University of London, London, SW17 0RE, UK., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medicine Science, University of Copenhagen, Copenhagen Ø, 2100, Denmark., Loos RJF; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medicine Science, University of Copenhagen, Copenhagen Ø, 2100, Denmark.; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, 10029, USA.; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, 10029, USA., Heckbert SR; Department of Epidemiology, University of Washington, Seattle, 98195, USA., Vollenweider P; Department of Medicine, Internal Medicine, Lausanne University hospital, Lausanne, 1015, Switzerland., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, Scotland, UK., Stefansson K; deCODE genetics / Amgen Inc., Reykjavik, 102, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, 101, Iceland., Froguel P; Department of Metabolism, Imperial College London, London, W12 0HS, UK.; Inserm/CNRS UMR 1283/8199, Pasteur Institute of Lille, Lille University Hospital, EGID, Lille, 59000, France.; University of Lille, Lille, 59000, France., Groop L; Lund University Diabetes Center, Department of Clinical Sciences, Lund University, Malmö, 20502, Sweden.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, 00290, Finland., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., van Duijn CM; Genetic Epidemiology Unit, Dept. of Epidemiology, Erasmus University Medical Center, Rotterdam, 3000CA, Netherlands., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, 63108-2212, Campus Box 8506, USA., O'Donnell CJ; Cardiology Section, VA Boston Healthcare System, Harvard Medical School, Boston, MA, 02132, USA., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, FI-33521, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, FI-33521, Finland., Perola M; Department of Health, unit of genetics and biomarkers, , National Institute for Health and Welfare, Finland, Helsinki, FI-00290, Finland.; Department of molecular medicine, University of Helsinki, Helsinki, FI-00290, Finland., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Kardia SLR; Department of Epidemiology, University of Michigan, Ann Arbor, MI, 48109, USA., Erdmann J; Institute for Cardiogenetics, University of Lübeck, Lübeck, 23562, Germany., Palmer CNA; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, DD1 9SY, UK., Ohlsson C; Sahlgrenska Osteoporosis Centre, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 41345, Sweden.; Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, 41345, Sweden., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Eriksson JG; Department of General practice and primary care, University of Helsinki, Helsinki, 00014, Finland.; Department of Obstetrics and Gynecology, National University of Singapore, Singapore, 119228, Singapore.; Public health Research Program, Folkhalsan Research Center, Helsinki, 000250, Finland., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, 70808, USA., Moebus S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, 45122, Germany.; Centre for Urban Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, 45122, Germany., Kraft P; Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02112, USA., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Cusi D; Unit of Biomedicine, Bio4Dreams-Business Nursery for Life Sciences, Milano, 20121, Italy.; Institute of Biomedical Technologies, National Research Council of Italy, Segrate, (MI), 20090, Italy., Ferrucci L; Longitudinal Study Section, National Institute on Aging, Baltimore, 21224, USA., Ulivi S; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Girotto G; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, 34137, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, 34149, Italy., Correa A; Jackson Heart Study, University of Mississippi Medical Center, Jackson, 39216, USA., Kääb S; German Centre for Cardiovascular Research (DZHK), partner site: Munich Heart Alliance, Munich, 80802, Germany.; Department of Cardiology, University Hospital, LMU Munich, Munich, 81377, Germany., Peters A; Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; German Centre for Cardiovascular Research (DZHK), partner site: Munich Heart Alliance, Munich, 80802, Germany.; Chair of Epidemiology, Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Munich, 81377, Germany., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UB1 3HW, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore., Kooner JS; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, W12 0HS, UK., März W; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, 68167, Germany.; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, 68161, Germany., Rotter JI; Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA, Torrance, 90502, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, 90502, USA., Hicks AA; Institute for Biomedicine, Eurac Research, Bolzano, 39100, Italy., Smith JG; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, 221 85, Sweden.; Wallenberg Center for Molecular Medicine and Lund University Diabetes Center, Lund University, Lund, 221 84, Sweden.; The Wallenberg Laboratory/Department of Molecular and Clinical Medicine, Institute of Medicine, Gothenburg University and the Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, 413 45, Sweden., Kiemeney LALM; Radboud university medical center, Nijmegen, 6500 HB, the Netherlands., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2300 RC, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2300 RC, the Netherlands., Penninx BWJH; Department of Psychiatry, Amsterdam Public Health, Amsterdam UMC, Amsterdam UMC, Vrije Universiteit, Amsterdam, Amsterdam, 1081 HL, the Netherlands., Gyllensten U; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, 75108, Sweden., Wilson JF; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, Scotland, UK., Burgess S; MRC Biostatistics Unit, University of Cambridge, Cambridge, CB2 0SR, UK., Sundström J; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University Hospital, Uppsala, 75237, Sweden., Lieb W; Institute of Epidemiology and Biobank PopGen, Kiel University, Kiel, 24105, Germany., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, ZA, 2333, the Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, ZA, 2333, the Netherlands.; Netherlands Heart Institute, Utrecht, 3511 EP, the Netherlands., Eijgelsheim M; Department of Epidemiology, Erasmus Medical Center, Rotterdam, 3015GD, the Netherlands.; Department of Nephrology, University Medical Center Groningen, Groningen, 9700RB, the Netherlands., Lakatta ELM; Laboratory of Cardiovascular Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., Dörr M; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, 17475, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17475, Germany., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore.; Tsinghua Medicine, Tsinghua University, Beijing, 100084, China., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Riese H; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, FI-33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, FI-33014, Finland., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, 9700RB, the Netherlands., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, 9700RB, the Netherlands. P.vanderHarst@umcutrecht.nl.; Department of Cardiology, University medical Center Utrecht, Utrecht, 3584 Cx, the Netherlands. P.vanderHarst@umcutrecht.nl.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, 9700RB, the Netherlands. P.vanderHarst@umcutrecht.nl.
Publikováno v:
Nature communications [Nat Commun] 2023 Aug 02; Vol. 14 (1), pp. 4646. Date of Electronic Publication: 2023 Aug 02.
Autor:
McAllan L; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.; MRC London Institute of Medical Sciences, London, W12 0NN, UK., Baranasic D; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.; MRC London Institute of Medical Sciences, London, W12 0NN, UK., Villicaña S; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Brown S; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.; MRC London Institute of Medical Sciences, London, W12 0NN, UK., Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UB1 3HW, UK., Lehne B; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK., Adamo M; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, Ground Floor West Wing, 250 Euston Road, London, NW1 2PG, UK., Jenkinson A; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, Ground Floor West Wing, 250 Euston Road, London, NW1 2PG, UK., Elkalaawy M; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, Ground Floor West Wing, 250 Euston Road, London, NW1 2PG, UK., Mohammadi B; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, Ground Floor West Wing, 250 Euston Road, London, NW1 2PG, UK., Hashemi M; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, Ground Floor West Wing, 250 Euston Road, London, NW1 2PG, UK., Fernandes N; Imperial BRC Genomics Facility, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Lambie N; Imperial BRC Genomics Facility, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Williams R; Imperial BRC Genomics Facility, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Christiansen C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; School of Mathematics and Statistics, Faculty of Science, Technology, Engineering and Mathematics, The Open University, Milton Keynes, UK., Yang Y; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; School of Cardiovascular and Metabolic Medicine and Sciences, James Black Centre, King's College London British Heart Foundation Centre of Excellence, 125 Coldharbour Lane, London, SE5 9NU, UK., Zudina L; Department of Clinical & Experimental Medicine, University of Surrey, Guildford, UK., Lagou V; Department of Microbiology and Immunology, Laboratory of Adaptive Immunity, KU Leuven, Leuven, Belgium.; VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium., Tan S; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Castillo-Fernandez J; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., King JWD; MRC London Institute of Medical Sciences, London, W12 0NN, UK., Soong R; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Pathology, National University Hospital, Singapore, Singapore., Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research Biomedical Research Centre, Imperial College London, London, UK., Scott J; National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK.; Imperial College Healthcare NHS Trust, London, W12 0HS, UK., Prokopenko I; Department of Clinical & Experimental Medicine, University of Surrey, Guildford, UK.; People-Centred Artificial Intelligence Institute, University of Surrey, Guildford, UK.; Institute of Biochemistry and Genetics, Ufa Federal Research Centre Russian Academy of Sciences, Ufa, Russian Federation., Cebola I; Section of Genetics and Genomics, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Loh M; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Lenhard B; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.; MRC London Institute of Medical Sciences, London, W12 0NN, UK., Batterham RL; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, Ground Floor West Wing, 250 Euston Road, London, NW1 2PG, UK.; Centre for Obesity Research, Rayne Institute, Department of Medicine, University College, London, WC1E 6JJ, UK.; National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, W1T 7DN, UK., Bell JT; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UB1 3HW, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, W12 0HS, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Kooner JS; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UB1 3HW, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK.; Imperial College Healthcare NHS Trust, London, W12 0HS, UK., Scott WR; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, W12 0NN, UK. w.scott@imperial.ac.uk.; MRC London Institute of Medical Sciences, London, W12 0NN, UK. w.scott@imperial.ac.uk.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK. w.scott@imperial.ac.uk.; Imperial College Healthcare NHS Trust, London, W12 0HS, UK. w.scott@imperial.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2023 May 15; Vol. 14 (1), pp. 2784. Date of Electronic Publication: 2023 May 15.
Autor:
Subkhankulova T; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Camargo Sosa K; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Uroshlev LA; Vavilov Institute of General Genetics, Russian Academy of Sciences, Ul. Gubkina 3, Moscow, 119991, Russia., Nikaido M; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK.; Graduate School of Science, University of Hyogo, Ako-gun, Hyogo Pref., 678-1297, Japan., Shriever N; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Kasianov AS; Vavilov Institute of General Genetics, Russian Academy of Sciences, Ul. Gubkina 3, Moscow, 119991, Russia.; Department of Medical and Biological Physics, Moscow Institute of Physics and Technology, 9 Institutskiy per., Dolgoprudny, Moscow Region, 141701, Russia.; A.A. Kharkevich Institute for Information Transmission Problems (IITP), Russian Academy of Sciences, Bolshoy Karetny per. 19, build.1, Moscow, 127051, Russia., Yang X; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK.; The MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, PR China., Rodrigues FSLM; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Carney TJ; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK.; Lee Kong Chian School of Medicine, Experimental Medicine Building, Yunnan Garden Campus, Nanyang Technological University, 59 Nanyang Drive, Yunnan Garden, 636921, Singapore., Bavister G; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Schwetlick H; Department of Mathematical Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Dawes JHP; Department of Mathematical Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Rocco A; Department of Microbial Sciences, FHMS, University of Surrey, GU2 7XH, Guildford, UK.; Department of Physics, FEPS, University of Surrey, GU2 7XH, Guildford, UK., Makeev VJ; Vavilov Institute of General Genetics, Russian Academy of Sciences, Ul. Gubkina 3, Moscow, 119991, Russia.; Department of Medical and Biological Physics, Moscow Institute of Physics and Technology, 9 Institutskiy per., Dolgoprudny, Moscow Region, 141701, Russia.; Laboratory 'Regulatory Genomics', Institute of Fundamental Medicine and Biology, Kazan Federal University, 18 Kremlyovskaya street, Kazan, 420008, Russia., Kelsh RN; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK. bssrnk@bath.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2023 Mar 06; Vol. 14 (1), pp. 1258. Date of Electronic Publication: 2023 Mar 06.
Autor:
Wielscher M; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. matthias.wielscher@meduniwien.ac.at.; Department of Dermatology, Medical University of Vienna, Vienna, Austria. matthias.wielscher@meduniwien.ac.at., Mandaviya PR; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.; Maastricht Centre for Systems Biology (MaCSBio), Maastricht University, Maastricht, The Netherlands., Kuehnel B; Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany., Joehanes R; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Mustafa R; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Robinson O; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Zhang Y; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany., Bodinier B; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Walton E; Department of Psychology, University of Bath, Bath, UK.; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK., Mishra PP; Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Centre, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Schlosser P; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Wilson R; Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany., Tsai PC; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Biomedical Sciences, Chang Gung University, Taoyuan City, Taiwan., Palaniswamy S; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Pentti Kaiteran katu 1, Linnanmaa, Oulu, Finland., Marioni RE; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Fiorito G; Laboratory of Biostatistics, Department of Biomedical Sciences, University of Sassari, Sassari, Italy.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Cugliari G; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Karhunen V; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Ghanbari M; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Department of Genetics, Mashhad University of Medical Sciences, Mashhad, Iran., Psaty BM; Cardiovacular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Loh M; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Mandalay Road, Singapore, Singapore., Bis JC; Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, WA, USA., Lehne B; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Sotoodehnia N; Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, WA, USA., Deary IJ; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK., Chadeau-Hyam M; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Brody JA; Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, WA, USA., Cardona A; MRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Selvin E; Dept. of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Smith AK; Departments of Gynecology and Obstetrics & Psychiatry and Behavioral Science, Emory University School of Medicine, Atlanta, GA, USA., Miller AH; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia., Torres MA; Department of Radiation Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Gào X; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany., van Meurs JBJ; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Graf-Schindler J; Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany., Rathmann W; Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Resesarch at Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Koenig W; Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany., Peters A; Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Weninger W; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Farlik M; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Zhang T; Deptarment of Biostatistics, School of Public Health, Shandong University, Jinan, China., Chen W; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Xia Y; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Nauck M; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Doerr M; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Lehtimäki T; Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Centre, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Guan W; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Milani L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Tanaka T; Translational Gerontology Branch, Biomedical Research Center, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Fisher K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia., Waite LL; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA., Kasela S; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Vineis P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, The Netherlands., van der Harst P; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Iacoviello L; Department of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, IS, Italy.; Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese-Como, Italy., Sacerdote C; Unit of Cancer Epidemiology, Citta' della Salute e della Scienza Hospital and Centre for Cancer Prevention, Turin, Italy., Panico S; Dipartimento di Medicina Clinica e Chirurgia Federico II University, Naples, Italy., Krogh V; Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Tumino R; Cancer Registry and Histopathology Department, 'Civic - MPP Arezzo' Hospital, ASP Ragusa, Ragusa, Italy., Tzala E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Matullo G; Department of Medical Sciences, University of Turin, Turin, Italy.; AOU Città della Salute e della Scienza di Torino, Torino, Italy., Hurme MA; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Raitakari OT; Research centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland., Colicino E; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Baccarelli AA; Laboratory of Environmental Epigenetics, Departments of Environmental Health Sciences and Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA., Kähönen M; Finnish Cardiovascular Research Centre, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Herzig KH; Research Unit of Biomedicine, Medical Research Center, Faculty of Medicine, University of Oulu, and Oulu University Hospital, Oulu, Finland.; Department of Gastroenterology and Metabolism, Institute of Pediatrics, Poznan University of Medical Sciences, Poznan, Poland., Li S; Children's Minnesota Research Institute, Children's Minnesota, Minneapolis, MN, USA., Conneely KN; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA., Kooner JS; National Heart and Lung Institute, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Southall, UK., Köttgen A; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.; Dept. of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Heijmans BT; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Relton C; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK., Ong KK; MRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Bell JT; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Boerwinkle E; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Houston, TX, USA., Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Imperial Biomedical Research Centre, Imperial College London, London, UK.; British Heart Foundation, BHF, Centre for Research Excellence, Imperial College London, London, UK., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.; Network Aging Research, Heidelberg University, Heidelberg, Germany., Beekman M; Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands., Levy D; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Waldenberger M; Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Mandalay Road, Singapore, Singapore.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Southall, UK., Dehghan A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; UK Dementia Research Institute at Imperial College London, London, UK., Järvelin MR; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. m.jarvelin@imperial.ac.uk.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Pentti Kaiteran katu 1, Linnanmaa, Oulu, Finland. m.jarvelin@imperial.ac.uk.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland. m.jarvelin@imperial.ac.uk.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK. m.jarvelin@imperial.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2022 May 03; Vol. 13 (1), pp. 2408. Date of Electronic Publication: 2022 May 03.
Autor:
Nasteska D; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Fine NHF; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Ashford FB; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Cuozzo F; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Viloria K; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Smith G; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Dahir A; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Dawson PWJ; School of Sport, Exercise and Rehabilitation Science, University of Birmingham, Edgbaston, UK.; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Birmingham, Edgbaston, UK., Lai YC; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; School of Sport, Exercise and Rehabilitation Science, University of Birmingham, Edgbaston, UK.; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Birmingham, Edgbaston, UK., Bastidas-Ponce A; Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD), D-85764, Neuherberg, Germany.; Institute of Stem Cell Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; Technical University of Munich, School of Medicine, Munich, Germany., Bakhti M; Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD), D-85764, Neuherberg, Germany.; Institute of Stem Cell Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany., Rutter GA; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Department of Metabolism, Reproduction, and Digestion, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Nanyang, Singapore., Fiancette R; Institute of Immunology & Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Nano R; San Raffaele Diabetes Research Institute, IRCCS Ospedale, San Raffaele, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Piemonti L; San Raffaele Diabetes Research Institute, IRCCS Ospedale, San Raffaele, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Lickert H; Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD), D-85764, Neuherberg, Germany.; Institute of Stem Cell Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; Technical University of Munich, School of Medicine, Munich, Germany., Zhou Q; Division of Regenerative Medicine, Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Akerman I; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Hodson DJ; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK. d.hodson@bham.ac.uk.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK. d.hodson@bham.ac.uk.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK. d.hodson@bham.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2021 Jul 20; Vol. 12 (1), pp. 4521. Date of Electronic Publication: 2021 Jul 20.
Autor:
Goodrich JK; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Singer-Berk M; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Son R; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sveden A; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wood J; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., England E; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Cole JB; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Weisburd B; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Watts N; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Caulkins L; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Dornbos P; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Koesterer R; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Zappala Z; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Zhang H; School of Medicine, University of Maryland Baltimore, Baltimore, MD, USA., Maloney KA; School of Medicine, University of Maryland Baltimore, Baltimore, MD, USA., Dahl A; Department of Neurology, UCLA, Los Angeles, CA, USA., Aguilar-Salinas CA; Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico., Atzmon G; Department of Medicine, Albert Einstein College of Medicine, New York, NY, USA.; Faculty of Natural Science, University of Haifa, Haifa, Israel.; Department of Genetics, Albert Einstein College of Medicine, New York, NY, USA., Barajas-Olmos F; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Barzilai N; Department of Medicine, Albert Einstein College of Medicine, New York, NY, USA.; Department of Genetics, Albert Einstein College of Medicine, New York, NY, USA., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville and Edinburg, TX, USA., Boerwinkle E; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Bottinger E; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bowden DW; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Centeno-Cruz F; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Chami N; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Ichan School of Medicine at Mount Sinai, New York, NY, USA., Chan E; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Chan J; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Cho YS; Department of Biomedical Science, Hallym University, Chuncheon, South Korea., Contreras-Cubas C; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Córdova E; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., DeFronzo RA; Department of Medicine, University of Texas Health San Antonio (aka University of Texas Health Science Center at San Antonio), San Antonio, TX, USA., Duggirala R; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville and Edinburg, TX, USA., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Garay-Sevilla ME; Department of Medical Science, División of Health Science, University of Guanjuato. Campus León. León, Guanjuato, Mexico., García-Ortiz H; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Gieger C; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Glaser B; Endocrinology and Metabolism Service, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., González-Villalpando C; Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Instituto Nacional de Salud Publica, Cuernavaca, Mexico., Gonzalez ME; Centro de Estudios en Diabetes, Mexico City, Mexico., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Genetics Finland, University of Helsinki, Helsinki, Finland., Gross M; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Haiman C; Department of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA., Han S; Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, South Korea., Hanis CL; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Heard-Costa NL; Boston University and National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Henderson BE; Department of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA., Hernandez JMM; Department of Medical Science, División of Health Science, University of Guanjuato. Campus León. León, Guanjuato, Mexico., Hwang MY; Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, South Korea., Islas-Andrade S; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Jørgensen ME; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.; Greenland Centre for Health Research, University of Greenland, Nuuk, Greenland., Kang HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Kim BJ; Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, South Korea., Kim YJ; Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, South Korea., Koistinen HA; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; University of Helsinki and Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kooner JS; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Kwak SH; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lange L; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Lee JY; Oneomics Soonchunhyang Mirae Medical Center, Bucheon-si Gyeonggi-do, Republic of Korea., Lee J; Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, South Korea., Lehman DM; Department of Medicine, University of Texas Health San Antonio (aka University of Texas Health Science Center at San Antonio), San Antonio, TX, USA., Linneberg A; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark., Liu J; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Ichan School of Medicine at Mount Sinai, New York, NY, USA., Lyssenko V; Centro de Estudios en Diabetes, Mexico City, Mexico.; Department of Clinical Science, University of Bergen, Bergen, Norway., Ma RCW; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Martínez-Hernández A; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Meigs JB; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Meitinger T; Institute of Human Genetics, Technical University of Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Mendoza-Caamal E; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Mohlke KL; Department of Genetics, University of North Carolina Chapel Hill, Chapel Hill, NC, USA., Morris AD; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Morrison AC; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Ng MCY; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Nilsson PM; Department of Clinical Sciences, Medicine, Lund University, Malmö, Sweden., O'Donnell CJ; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Section of Cardiology, Department of Medicine, VA Boston Healthcare, Boston, MA, USA.; Brigham and Women's Hospital, Boston, MA, USA.; Intramural Administration Management Branch, National Heart Lung and Blood Institute, NIH, Framingham, MA, USA., Orozco L; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, University of Dundee, Dundee, UK., Park KS; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea., Post WS; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Preuss M; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Research Institute, Seattle, WA, USA., Reiner AP; Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Revilla-Monsalve C; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation (formerly Los Angeles Biomedical Research Institute) at Harbor-UCLA Medical Center, Torrance, CA, USA., Saleheen D; Division of Translational Medicine and Human Genetics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA.; Center for Non-Communicable Diseases, Karachi, Pakistan., Schurmann C; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Digital Health Center, Hasso Plattner Institute, University of Potsdam, Prof.-Dr.-Helmert-Str. 2-3, Potsdam, Germany.; Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA., Sim X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Sladek R; Department of Human Genetics, McGill University, Montreal, QC, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McGill University, Montreal, QC, Canada.; McGill University and Génome Québec Innovation Centre, Montreal, QC, Canada., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., So WY; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany.; Institute for Medical Informatics Biometry and Epidemiology, Ludwig-Maximilians University, Munich, Germany., Strom TM; Institute of Human Genetics, Technical University of Munich, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Tai ES; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Tam CHT; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China., Teo YY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore., Thameem F; Department of Biochemistry, Faculty of Medicine, Health Science Center, Kuwait University, Safat, Kuwait., Tomlinson B; Faculty of Medicine, Macau University of Science & Technology, Macau, China., Tracy RP; Department of Pathology and Laboratory Medicine, The Robert Larner M.D. College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Biochemistry, The Robert Larner M.D. College of Medicine, University of Vermont, Burlington, VT, USA., Tuomi T; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Genetics Finland, University of Helsinki, Helsinki, Finland.; Folkhälsan Research Centre, Helsinki, Finland.; Department of Endocrinology, Abdominal Centre, Helsinki University Hospital, Helsinki, Finland.; Research Programs Unit, Clinical and Molecular Medicine, University of Helsinki, Helsinki, Finland., Tuomilehto J; Public Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of International Health, National School of Public Health, Instituto de Salud Carlos III, Madrid, Spain., Tusié-Luna T; Unidad de Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.; Departamento de Medicina Genómica y Toxiología Ambiental, Instituto de Investigaciones Biomédicas, UNAM, Mexico City, Mexico., van Dam RM; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA., Vasan RS; Boston University and National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Preventive Medicine & Epidemiology, and Cardiovascular Medicine, Medicine, Boston University School of Medicine, and Epidemiology, Boston University School of Public health, Boston, MA, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Witte DR; Department of Public Health, Aarhus University, Aarhus, Denmark.; Danish Diabetes Academy, Odense, Denmark., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Burtt NP; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Zaitlen N; Department of Neurology, UCLA, Los Angeles, CA, USA., McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Genentech, South San Francisco, CA, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Pollin TI; School of Medicine, University of Maryland Baltimore, Baltimore, MD, USA., Flannick J; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Mercader JM; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., O'Donnell-Luria A; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Baxter S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Florez JC; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., MacArthur DG; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Centre for Population Genomics, Garvan Institute of Medical Research, UNSW Sydney, Sydney, NSW, Australia.; Centre for Population Genomics, Murdoch Children's Research Institute, Melbourne, VIC, Australia., Udler MS; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. mudler@mgh.harvard.edu.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. mudler@mgh.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA, USA. mudler@mgh.harvard.edu.
Publikováno v:
Nature communications [Nat Commun] 2021 Jun 09; Vol. 12 (1), pp. 3505. Date of Electronic Publication: 2021 Jun 09.
Autor:
Nasteska D; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Fine NHF; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Ashford FB; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Cuozzo F; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Viloria K; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Smith G; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Dahir A; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Dawson PWJ; School of Sport, Exercise and Rehabilitation Science, University of Birmingham, Edgbaston, UK.; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Birmingham, Edgbaston, UK., Lai YC; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; School of Sport, Exercise and Rehabilitation Science, University of Birmingham, Edgbaston, UK.; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Birmingham, Edgbaston, UK., Bastidas-Ponce A; Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD), D-85764, Neuherberg, Germany.; Institute of Stem Cell Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; Technical University of Munich, School of Medicine, Munich, Germany., Bakhti M; Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD), D-85764, Neuherberg, Germany.; Institute of Stem Cell Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany., Rutter GA; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Department of Metabolism, Reproduction, and Digestion, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Nanyang, Singapore., Fiancette R; Institute of Immunology & Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Nano R; San Raffaele Diabetes Research Institute, IRCCS Ospedale, San Raffaele, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Piemonti L; San Raffaele Diabetes Research Institute, IRCCS Ospedale, San Raffaele, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Lickert H; Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD), D-85764, Neuherberg, Germany.; Institute of Stem Cell Research, Helmholtz Zentrum München, D-85764, Neuherberg, Germany.; Technical University of Munich, School of Medicine, Munich, Germany., Zhou Q; Division of Regenerative Medicine, Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Akerman I; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Hodson DJ; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham, UK. d.hodson@bham.ac.uk.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK. d.hodson@bham.ac.uk.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK. d.hodson@bham.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2021 Jan 29; Vol. 12 (1), pp. 674. Date of Electronic Publication: 2021 Jan 29.
Autor:
Clark DW; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Osaka, 565-0871, Japan., Moore KHS; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Mason D; Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust, Bradford, BD96RJ, UK., Pirastu N; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Gandin I; Research Unit, Area Science Park, Trieste, 34149, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Mattsson H; Unit of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Barnes CLK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.; Cardiovascular Epidemiology Unit, Department of Public health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Deelen P; Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, 9700 RB, The Netherlands., Rohde R; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27514, USA., Schurmann C; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, 10029, USA., Guo X; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, Middlesex, Middlesex, UB1 3HW, UK., Medina-Gomez C; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, 3015 CN, The Netherlands., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 17177, Sweden., Bao Y; Institute for Social and Economic Research, University of Essex, Colchester, CO4 3SQ, UK., Bartz TM; Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington, Seattle, WA, 98101, USA., Baumbach C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Biino G; Institute of Molecular Genetics, National Research Council of Italy, Pavia, 27100, Italy., Bixley MJ; Department of Biochemistry, University of Otago, Dunedin, 9054, New Zealand., Brumat M; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Chai JF; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, 117549, Singapore., Corre T; Department of Computational Biology, University of Lausanne, Lausanne, 1011, Switzerland.; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., Cousminer DL; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Dekker AM; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Eccles DA; Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, 4059, Australia.; Malaghan Institute of Medical Research, Wellington, 6242, New Zealand., van Eijk KR; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Fuchsberger C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Gao H; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK., Germain M; INSERM UMR_S 1166, Sorbonne Universités, Paris, 75013, France.; ICAN Institute for Cardiometabolism and Nutrition, Paris, 75013, France., Gordon SD; QIMR Berghofer Institute of Medical Research, Brisbane, Australia., de Haan HG; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, 8036, Austria.; Institute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, 8036, Austria., Huerta-Chagoya A; CONACyT, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, 03940, México., Igartua C; Department of Human Genetics, University of Chicago, Chicago, IL, 60637, USA., Jansen IE; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands.; Alzheimer Center Department of Neurology, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, 1081HV, The Netherlands., Jia Y; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Kacprowski T; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, 17475, Germany.; Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising-Weihenstephan, 85354, Germany., Karlsson T; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 75108, Uppsala, Sweden., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, 68167, Germany., Li SA; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Inc., Frederick National Lab for Cancer Research, Frederick, MD, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Matsuda K; Department of Computational Biology and Medical Sciences, Graduate school of Frontier Sciences, The University of Tokyo, Tokyo, 108-8639, Japan., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Meng W; Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee, Dundee, UK., Montasser ME; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, 21201, USA.; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, 21201, USA., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Munz M; Institute for Cardiogenetics, University of Lübeck, Lübeck, 23562, Germany.; DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, Lübeck, 23562, Germany.; University Heart Center Luebeck, Lübeck, 23562, Germany.; Charité - University Medicine Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Dental and Craniofacial Sciences, Department of Periodontology and Synoptic Dentistry, Berlin, Germany., Nutile T; Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR, Naples, 80131, Italy., Palviainen T; Finnish Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland., Prasad G; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi, 110020, India., Prasad RB; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, 20502, Sweden., Priyanka TDS; Genomic Research on Complex diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, 500007, India., Rizzi F; ePhood Scientific Unit, ePhood SRL, Bresso (Milano), 20091, Italy.; Department of Health Sciences, University of Milano, Milano, 20139, Italy., Salvi E; Department of Health Sciences, University of Milano, Milano, 20139, Italy.; Neuroalgology Unit, IRCCS Foundation Carlo Besta Neurological Institute, Milano, 20133, Italy., Sapkota BR; Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA., Shriner D; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Skotte L; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, DK-2300, Denmark., Smart MC; Institute for Social and Economic Research, University of Essex, Colchester, CO4 3SQ, UK., Smith AV; Icelandic Heart Association, Kopavogur, 201, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, 101, Iceland., van der Spek A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Spracklen CN; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Strawbridge RJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.; Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 76, Sweden., Tajuddin SM; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, Maryland, 21224, USA., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, 2300 RC, the Netherlands.; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, 2300RC, the Netherlands., Turman C; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands, Groningen, 9713 GZ, the Netherlands., Viberti C; Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy, Turin, 10126, Italy., Wang L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, Saint Louis, MO, 63110-1093, USA., Warren HR; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Wootton RE; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK.; School of Psychological Science, University of Bristol, Bristol, BS8 1TU, UK., Yanek LR; Department of Medicine, GeneSTAR Research Program, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA., Yao J; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Yousri NA; Department of Genetic Medicine, Weill Cornell Medicine Qatar, Doha, Qatar.; Computer and Systems Engineering, Alexandria University, Alexandria, Egypt., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Adeyemo AA; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Afaq S; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Aguilar-Salinas CA; Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, 14080, México.; Unidad de Investigacion de Enfermades Metabolicas, Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, N.L., 64710, México., Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka, 812-8582, Japan., Albert ML; Immunobiology of Dendritic Cells, Institut Pasteur, Paris, 75015, France.; Inserm U1223, Paris, 75015, France.; Centre for Translational Research, Institut Pasteur, Paris, 75015, France.; Department of Cancer Immunology, Genentech Inc, San Francisco, California, 94080, USA., Allison MA; Division of Preventive Medicine, Department of Family Medicine and Public Health, UC San Diego School of Medicine, La Jolla, California, 92093, USA., Alver M; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore, 169857, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 119228, SG, Singapore., Azizi F; Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Boerwinkle E; Health Science Center at Houston, UTHealth School of Public Health, University of Texas, Houston, TX, 77030, USA., Borja JB; USC-Office of Population Studies Foundation, Inc., Department of Nutrition and Dietetics, Talamban, University of San Carlos, Cebu City, 6000, Cebu, Philippines., de Borst GJ; Department of Vascular Surgery, Division of Surgical Specialties, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Digital Health Center, Hasso Plattner Institute, Universität Potsdam, Potsdam, 14482, Germany., Broer L; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Campbell H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Chanock S; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Chee ML; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore., Chen G; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Chen YI; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Chiu YF; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan, Taiwan., Cocca M; Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, 34137, Italy., Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA., Concas MP; Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, 34137, Italy., Corley J; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Cugliari G; Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy, Turin, 10126, Italy., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, 117549, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, SG, Singapore.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, 02115, USA., Damulina A; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, 8036, Austria., Daneshpour MS; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., Day FR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Delgado GE; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, 68167, Germany., Dhana K; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, 02115, USA.; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA., Doney ASF; MEMO Research, Molecular and Clinical Medicine, University of Dundee, Dundee, DD19SY, UK., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17475, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475, Germany., Doumatey AP; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Dzimiri N; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, KSA, 12713, Saudi Arabia., Ebenesersdóttir SS; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; Department of Anthropology, University of Iceland, Reykjavik, 101, Iceland., Elliott J; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK.; National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare NHS Trust and Imperial College London, London, UK.; UK Dementia Research Institute (UK DRI) at Imperial College London, London, UK.; Health Data Research UK - London, London, England., Ewert R; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17475, Germany., Felix JF; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, 3015 CN, The Netherlands.; Department of Pediatrics, Erasmus University Medical Center, Rotterdam, 3015CN, The Netherlands., Fischer K; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27101, US., Girotto G; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Medical Genetics, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy., Goel A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DU, UK., Gögele M; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Goodarzi MO; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, 90048, USA., Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27514, USA., Granot-Hershkovitz E; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Grodstein F; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Guarrera S; Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy, Turin, 10126, Italy., Gudbjartsson DF; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, 101, Iceland., Guity K; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., Gunnarsson B; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Guo Y; Chinese Academy of Medical Sciences, Beijing, 100730, China., Hagenaars SP; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, 90089, USA., Halevy A; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, Maryland, 21224, USA., Hedayati M; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., van Heel DA; Blizard Institute, Queen Mary University of London, London, E1 2AT, UK., Hirata M; Laboratory of Genome Technology, Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan., Höfer I; Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands., Hsiung CA; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan, Taiwan., Huang J; Shanghai Institute of Hematology, State Key Laboratory Of Medical Genomics, Rui-jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 200025, China., Hung YJ; Division of Endocrine and Metabolism, Tri-Service General Hospital Songshan branch, Taipei, Taiwan, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan, Taiwan., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Jagadeesan A; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; Department of Anthropology, University of Iceland, Reykjavik, 101, Iceland., Jousilahti P; Unit of Public Health Promotion, National Institute for Health and Welfare, Helsinki, Finland., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan., Kanai M; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA., Kerrison ND; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Kessler T; Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, Munich, 80636, Germany., Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB2 0SR, UK., Khor CC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore, 138672, Singapore., de Kleijn DPV; Department of Vascular Surgery, Division of Surgical Specialties, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands., Koh WP; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, 117549, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore, 169857., Kolcic I; Centre for Global Health, Faculty of Medicine, University of Split, Split, Croatia., Kraft P; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, 02115, USA., Krämer BK; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, 68167, Germany., Kutalik Z; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, Maryland, 21224, USA., Lawlor DA; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK.; Bristol NIHR Biomedical Research Centre, Bristol, BS8 2BN, UK.; Population Health Science, Bristol Medical School, Bristol, BS8 2BY, UK., Lee IT; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan, Taipei, 112, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan, Taichung City, 402, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan., Lerch MM; Department of Internal Medicine A, University Medicine Greifswald, Greifswald, 17475, Germany., Li L; Department of Epidemiology and Biostatistics, Peking University Health Science Centre, Peking University, Beijing, 100191, China., Liu J; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, SG, Singapore.; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore, 138672, Singapore., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), Singapore, 138648, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 117596, Singapore., London SJ; National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, Durham, NC, 27709, USA., Loomis S; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, 10029, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Mägi R; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Manichaikul AW; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA., Manunta P; Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Università Vita Salute San Raffaele, Milano, 20132, Italy., Másson G; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Matoba N; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan., Mei XW; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Meisinger C; Helmholtz Zentrum München, Independent Research Group Clinical Epidemiology, Neuherberg, 85764, Germany., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum Muenchen, Neuherberg, 85764, Germany.; Institute of Human Genetics, Technical University of Munich, Munich, 81675, Germany.; DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, 80802, Germany., Mezzavilla M; Medical Genetics, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy., Milani L; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., Millwood IY; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Momozawa Y; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan., Moore A; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Morange PE; Laboratory of Haematology, La Timone Hospital, Marseille, France.; INSERM UMR_S 1263, Center for CardioVascular and Nutrition research (C2VN), Aix-Marseille University, Marseille, France., Moreno-Macías H; Departamento de Economía, Universidad Autónoma Metropolitana, Mexico, 09340, México., Mori TA; Medical School, The University of Western Australia, Perth, Western Australia/Australia, 6009, Australia., Morrison AC; The University of Texas Health Science Center at Houston, School of Public Health, Department of Epidemiology, Human Genetics and Environmental Sciences, Houston, Texas, 77030, USA., Muka T; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland., Murakami Y; Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan., Murray AD; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, AB25 2ZD, UK., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Mychaleckyj JC; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA., Nalls MA; Laboratory of Neurogenetics, Bethesda, MD, 20892, USA.; Data Tecnica International LLC, Glen Echo, MD, 20812, USA., Nauck M; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, 17475, Germany., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington, Oxford, OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Ong KK; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.; Department of Paediatrics, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Orozco L; Instituto Nacional de Medicina Genómica, Mexico, 14610, México., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, G12 8TA, UK., Pálsson G; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Pankow JS; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, 55454, USA., Pattaro C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Pattie A; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Polasek O; Centre for Global Health, Faculty of Medicine, University of Split, Split, Croatia.; Gen-info Ltd, Zagreb, Croatia, Zagreb, Select a Province, 10000, Croatia., Poulter N; International Centre for Circulatory Health, Imperial College London, London, W2 1PG, UK.; Imperial Clinical Trials Unit, Imperial College London, London, London, W12 7TA, UK., Pramstaller PP; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Quintana-Murci L; Human Evolutionary Genetics Unit, Institut Pasteur, Paris, 75015, France.; Centre National de la Recherche Scientifique (CNRS) UMR2000, Paris, 75015, France.; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris, 75015, France., Räikkönen K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, University of Helsinki, Helsinki, 00014, Finland., Ralhan S; Hero Heart Institute and Dyanand Medical College and Hospital, Ludhiana, Punjab, India., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA., van Rheenen W; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Rietveld CA; Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, 3062 PA, The Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus University Rotterdam, Rotterdam, 3062 PA, The Netherlands., Robino A; Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, 34137, Italy., van Rooij FJA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Ruggiero D; Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR, Naples, 80131, Italy.; IRCCS Neuromed, Pozzilli (IS), 86077, Italy., Saba Y; Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry, Medical University of Graz, 8010, Graz, Austria., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore, 169857, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 119228, SG, Singapore., Sabater-Lleal M; Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 76, Sweden.; Unit of Genomics of Complex Diseases, Institut de Recerca Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Barcelona, Spain., Sala CF; San Raffaele Research Institute, Milano, Italy., Salomaa V; Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, FI-00271, Finland., Sandow K; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Schmidt H; Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry, Medical University of Graz, 8010, Graz, Austria., Scott LJ; Department of Biostatistics, and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, 48109, USA., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Sedaghati-Khayat B; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 76, Sweden.; Dept of Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala, SE-752 37, Uppsala, Sweden., van Setten J; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3485 CX, Netherlands., Sever PJ; International Centre for Circulatory Health, Imperial College London, London, W2 1PG, UK., Sheu WH; School of Medicine, National Defense Medical Center, Taipei, Taiwan, Taiwan.; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan, Taiwan.; Institute of Medical Technology, National Chung-Hsing University, Taichung, Taiwan, Taiwan., Shi Y; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore., Shrestha S; Genomic Research on Complex diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, 500007, India.; School of Basic and Applied Sciences, Dayananda Sagar University, Bangalore, Karnataka, 560078, India., Shukla SR; Diabetes Unit, KEM Hospital and Research Centre, Pune, Maharashtra, 411101, India.; Symbiosis Statistical Institute, Symbiosis International University, Pune, Maharashtra, 411007, India., Sigurdsson JK; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Sikka TT; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Singh JR; Panjab University, Chandigarh, India., Smith BH; Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK., Stančáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Stanton A; RCSI Molecular & Cellular Therapeutics (MCT), Royal College of Surgeons in Ireland, RCSI Education & Research Centre, Beaumont Hospital, Dublin 9, Ireland., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, EH8 9JZ, Scotland., Stefansdottir L; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Straker L; School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University, Perth, Western Australia/Australia, 6102, Australia., Sulem P; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Sveinbjornsson G; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Swertz MA; Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, 9700 RB, The Netherlands., Taylor AM; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Taylor KD; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Terzikhan N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; Department of Respiratory Medicine, Ghent University Hospital, Ghent, 9000, Belgium., Tham YC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore, 169857, Singapore., Thorleifsson G; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Thorsteinsdottir U; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, 101, Iceland., Tillander A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 17177, Sweden., Tracy RP; Department of Pathology, University of Vermont, Colchester, VT, 05446, USA., Tusié-Luna T; Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, UNAM, Mexico, 04510, México.; Unidad De Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, 14080, México., Tzoulaki I; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Vaccargiu S; Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy, Rome, Italy., Vangipurapu J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Veldink JH; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, Scotland., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, 17475, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475, Germany., Vuoksimaa E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland., Wakil SM; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, KSA, 12713, Saudi Arabia., Waldenberger M; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Wander GS; Department of Cardiology, Hero DMC Heart Institute, Dayanand Medical College & Hospital, Ludhiana, Punjab, 141001, India., Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, China, 100005, China., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Wild S; Centre for Population Health Sciences, Usher Institute of Population Health and Informatics, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Yajnik CS; Diabetes Unit, K.E.M. Hospital Research Centre, Pune, MAH, 411011, India., Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Zeng L; Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, Munich, 80636, Germany., Zhang L; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore., Zhou J; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, WC1E 6DD, UK.; Durrer Center for Cardiovascular Research, Netherlands Heart Institute, Utrecht, Netherlands.; Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, UK., Bakker SJL; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, 9713GZ, The Netherlands., Becker DM; Department of Medicine, GeneSTAR Research Program, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, 60612, USA., van den Berg LH; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Berndt SI; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Bharadwaj D; Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Bochud M; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland., Boehnke M; Department of Biostatistics, and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, 48109, USA., Bouchard C; Pennington Biomedical Research Center, Baton Rouge, Louisiane, 70808, USA., Bradfield JP; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Quantinuum Research LLC, San Diego, CA, 92101, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, 98101, USA., Campbell A; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Carmi S; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Caulfield MJ; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Cesarini D; Center for Experimental Social Science, Department of Economics, New York University, New York, New York, 10012, USA.; Research Institute for Industrial Economics (IFN), Stockholm, 102 15, Sweden., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, Middlesex, Middlesex, UB1 3HW, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.; Imperial College Healthcare NHS Trust, London, London, W12 0HS, UK., Chandak GR; Genomic Research on Complex diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, 500007, India., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore, 169857, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 119228, SG, Singapore., Ciullo M; Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR, Naples, 80131, Italy.; IRCCS Neuromed, Pozzilli (IS), 86077, Italy., Cornelis M; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Cusi D; Department of Health Sciences, University of Milano, Milano, 20139, Italy.; Institute of Biomedical Technologies Milano, National Research Council of Italy (CNR), Segrate (Milano), 20090, Italy.; Bio4Dreams Scientific Unit, Bio4Dreams SRL, Bio4Dreams - business nursery for life sciences, Milano, 20121, Italy., Smith GD; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK.; Population Health Science, Bristol Medical School, Bristol, BS8 2BY, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Dorajoo R; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore, 138672, Singapore., van Duijn CM; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Ellinghaus D; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 24105, Kiel, Germany., Erdmann J; Institute for Cardiogenetics, University of Lübeck, Lübeck, 23562, Germany., Eriksson JG; Department of General Practice and Primary health Care, University of Helsinki, Tukholmankatu 8 B, Helsinki, 00014, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.; Folkhälsan Research Centre, Helsinki, Finland.; Vasa Central Hospital, Vaasa, Finland., Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Evans MK; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, Maryland, 21224, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48014, USA., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, DK-2300, Denmark., Feitosa M; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, Saint Louis, MO, 63110-1093, USA., Foisy S; Montreal Heart Institute, Montreal, QC, Canada., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 24105, Kiel, Germany., Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Gasparini P; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Medical Genetics, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Gonzalez C; Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Cuernavaca, 01120, México., Goyette P; Montreal Heart Institute, Montreal, QC, Canada., Grant SFA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Griffiths LR; Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, 4059, Australia., Groop L; Finnish Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, 20502, Sweden., Gudnason V; Icelandic Heart Association, Kopavogur, 201, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, 101, Iceland., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 75108, Uppsala, Sweden., Hakonarson H; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Stockholm, 171 76, Sweden., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands, Groningen, 9713 GZ, the Netherlands., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore, Singapore., Hicks AA; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Hochner H; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Huikuri H; Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, 90014, Finland., Hunt SC; Department of Genetic Medicine, Weill Cornell Medicine Qatar, Doha, Qatar.; Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, 84108, USA., Jaddoe VWV; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, 3015 CN, The Netherlands.; Department of Pediatrics, Erasmus University Medical Center, Rotterdam, 3015CN, The Netherlands., De Jager PL; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, 650 West 168th street, PH19-311, Newyork, NY, 10032, USA.; Cell Circuits Program, Broad Institute, Cambridge, MA, 02142, USA., Johannesson M; Department of Economics, Stockholm School of Economics, Stockholm, SE-113 83, Sweden., Johansson Å; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 75108, Uppsala, Sweden., Jonas JB; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, China, 100005, China.; Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Mannheim, 698167, Germany., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, 2300 RC, the Netherlands., Junttila J; Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, 90014, Finland., Kaprio J; Finnish Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, FI-00014, Finland., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington, Oxford, OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Kumari M; Institute for Social and Economic Research, University of Essex, Colchester, CO4 3SQ, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., van der Laan SW; Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy, University Medical Center Utrecht, University of Utrecht, Utrecht, 3584 CX, Netherlands., Lahti J; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, University of Helsinki, Helsinki, 00014, Finland.; Helsinki Collegium for Advanced Studies, University of Helsinki, University of Helsinki, Helsinki, 00014, Finland., Laudes M; University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel, 24105, Germany., Lea RA; Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, 4059, Australia., Lieb W; Institute of Epidemiology and PopGen Biobank, University of Kiel, Kiel, Schleswig Holstein, 24105, Germany., Lumley T; Department of Statistics, University of Auckland, Auckland, New Zealand., Martin NG; QIMR Berghofer Institute of Medical Research, Brisbane, Australia., März W; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, 68167, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany., Matullo G; Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy, Turin, 10126, Italy., McCarthy MI; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington, Oxford, OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Medland SE; QIMR Berghofer Institute of Medical Research, Brisbane, Australia., Merriman TR; Department of Biochemistry, University of Otago, Dunedin, 9054, New Zealand., Metspalu A; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Meyer BF; Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, 11211, Saudi Arabia., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Montgomery GW; QIMR Berghofer Institute of Medical Research, Brisbane, Australia.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia., Mook-Kanamori D; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Munroe PB; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27514, USA., Nyholt DR; QIMR Berghofer Institute of Medical Research, Brisbane, Australia.; School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, QLD, 4059, Australia., O'connell JR; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, 21201, USA.; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, 21201, USA., Ober C; Department of Human Genetics, University of Chicago, Chicago, IL, 60637, USA., Oldehinkel AJ; Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Palmas W; Department of Medicine, Columbia University Medical Center, New York, New York, USA., Palmer C; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, The School of Medicine, University of Dundee, Dundee, DD1 9SY, UK., Pasterkamp GG; Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands., Patin E; Human Evolutionary Genetics Unit, Institut Pasteur, Paris, 75015, France.; Centre National de la Recherche Scientifique (CNRS) UMR2000, Paris, 75015, France.; 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Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 17177, Sweden., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, 3015 CN, The Netherlands., Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex, Middlesex, UB1 3HW, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK.; Imperial College Healthcare NHS Trust, London, London, W12 0HS, UK.; National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, 10029, USA.; 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Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia.; Program in Medical and Population Genetics, Broad Institute, Broad Institute, Cambridge, MASSACHUSETTS, 02142, USA., Helgason A; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; Department of Anthropology, University of Iceland, Reykjavik, 101, Iceland., Stefansson K; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, 101, Iceland., Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Kubo M; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan., Wilson JF; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland. jim.wilson@ed.ac.uk.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, Scotland. jim.wilson@ed.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2019 Oct 31; Vol. 10 (1), pp. 4957. Date of Electronic Publication: 2019 Oct 31.