Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ouwehand WH"'
Autor:
Schormair B; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. barbara.schormair@helmholtz-munich.de.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany. barbara.schormair@helmholtz-munich.de., Zhao C; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Bell S; Department of Oncology, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK., Didriksen M; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark., Nawaz MS; deCODE Genetics/Amgen, Reykjavik, Iceland., Schandra N; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Stefani A; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Högl B; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Dauvilliers Y; Sleep-Wake Disorders Center, Department of Neurology, Hôpital Gui-de-Chauliac, CHU Montpellier, Institut des Neurosciences de Montpellier, INSERM, Université de Montpellier, Montpellier, France., Bachmann CG; SomnoDiagnostics, Osnabrück, Germany.; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany., Kemlink D; Department of Neurology and Centre of Clinical Neuroscience, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic., Sonka K; Department of Neurology and Centre of Clinical Neuroscience, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic., Paulus W; Department of Neurology, Ludwig Maximilians University Munich, Munich, Germany., Trenkwalder C; Paracelsus-Elena-Klinik, Kassel, Germany.; Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany., Oertel WH; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Neurology, Philipps-University Marburg, Marburg, Germany., Hornyak M; Neuropsychiatry Centre Erding/München, Erding, Germany., Teder-Laving M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Hadjigeorgiou GM; Department of Neurology, Nicosia General Hospital Medical School, University of Cyprus, Nicosia, Cyprus., Polo O; Bragée ME/CFS Center, Stockholm, Sweden., Fietze I; Department of Pulmonology, Center of Sleep Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany., Ross OA; Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA., Wszolek ZK; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Ibrahim A; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Bergmann M; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Kittke V; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Harrer P; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Dowsett J; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Chenini S; Sleep-Wake Disorders Center, Department of Neurology, Hôpital Gui-de-Chauliac, CHU Montpellier, Institut des Neurosciences de Montpellier, INSERM, Université de Montpellier, Montpellier, France., Ostrowski SR; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Sørensen E; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Erikstrup C; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Pedersen OB; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark., Topholm Bruun M; Department of Clinical Immunology, Odense University Hospital, Odense, Denmark., Nielsen KR; Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Soranzo N; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Department of Human Genetics, the Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Ouwehand WH; Department of Haematology, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.; Department of Haematology, University College London Hospitals, London, UK., Roberts DJ; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Radcliffe Department of Medicine and National Health Service Blood and Transplant, Oxford, UK.; Department of Haematology and BRC Haematology Theme, Churchill Hospital, Headington, Oxford, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; Department of Human Genetics, the Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Burchell B; Magdalene College, Cambridge, UK., Furlotte NA; 23andMe, Inc., Sunnyvale, CA, USA., Nandakumar P; 23andMe, Inc., Sunnyvale, CA, USA., Earley CJ; Center for Restless Legs Syndrome, Department of Neurology, Johns Hopkins University, Baltimore, MD, USA., Ondo WG; Department of Neurology, Methodist Neurological Institute, Weill Cornell Medical School, Houston, TX, USA., Xiong L; The Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada., Desautels A; Centre d'Études Avancées en Médecine du Sommeil, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada.; Department of Neurosciences, Université de Montréal, Montreal, Quebec, Canada., Perola M; Clinical and Molecular Metabolism Research Program (CAMM), Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Public Health and Welfare, National Institute for Health and Welfare, Helsinki, Finland., Vodicka P; Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Science of Czech Republic, Prague, Czech Republic.; First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic., Dina C; L'institut du thorax, CNRS, INSERM, Nantes Université, Nantes, France., Stoll M; Department of Genetic Epidemiology, Institute for Human Genetics, University of Münster, Münster, Germany., Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Lieb W; PopGen Biobank and Institute of Epidemiology, Christian Albrechts University Kiel, Kiel, Germany., Stewart AFR; John and Jennifer Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Shah SH; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA., Gieger C; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), partner site Munich Heart Alliance, Hannover, Germany.; Chair of Epidemiology, Institute for Medical Information Processing, Biometry and Epidemiology, Medical Faculty, Ludwig-Maximilians-Universität München, Munich, Germany., Rye DB; Department of Neurology, Emory University, Atlanta, GA, USA., Rouleau GA; The Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Stefansson H; deCODE Genetics/Amgen, Reykjavik, Iceland., Ullum H; Statens Serum Institute, Copenhagen, Denmark., Stefansson K; deCODE Genetics/Amgen, Reykjavik, Iceland., Hinds DA; 23andMe, Inc., Sunnyvale, CA, USA., Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; Health Data Science Research Centre, Fondazione Human Technopole, Milan, Italy., Oexle K; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.; Neurogenetic Systems Analysis Group, Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Winkelmann J; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; German Center for Mental Health (DZPG), partner site Munich-Augsburg, Munich-Augsburg, Germany.
Publikováno v:
Nature genetics [Nat Genet] 2024 Jun; Vol. 56 (6), pp. 1090-1099. Date of Electronic Publication: 2024 Jun 05.
Autor:
Codd V; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK. vc15@le.ac.uk.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK. vc15@le.ac.uk., Wang Q; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Allara E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Musicha C; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Kaptoge S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK., Stoma S; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Jiang T; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Hamby SE; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Bountziouka V; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Budgeon CA; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.; School of Population and Global Health, University of Western Australia, Perth, Western Australia, Australia., Denniff M; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Swinfield C; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Papakonstantinou M; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Sheth S; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Nanus DE; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Warner SC; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Wang M; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Khera AV; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Eales J; Division of Cardiovascular Sciences, University of Manchester, Manchester, UK., Ouwehand WH; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, Cambridge, UK.; University College London Hospitals NHS Foundation Trust, London, UK., Thompson JR; Department of Health Sciences, University of Leicester, Leicester, UK., Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Sanger Institute, EMBL-European Bioinformatics Institute and University of Cambridge, Cambridge, UK., Wood AM; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Sanger Institute, EMBL-European Bioinformatics Institute and University of Cambridge, Cambridge, UK.; The Alan Turing Institute, London, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Sanger Institute, EMBL-European Bioinformatics Institute and University of Cambridge, Cambridge, UK., Danesh JN; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Sanger Institute, EMBL-European Bioinformatics Institute and University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, UK., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK. njs@le.ac.uk.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK. njs@le.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2021 Oct; Vol. 53 (10), pp. 1425-1433. Date of Electronic Publication: 2021 Oct 05.
Autor:
Võsa U; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. urmo.vosa@gmail.com.; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. urmo.vosa@gmail.com., Claringbould A; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. anniqueclaringbould@gmail.com.; Oncode Institute, Amsterdam, the Netherlands. anniqueclaringbould@gmail.com.; Structural & Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. anniqueclaringbould@gmail.com., Westra HJ; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., Bonder MJ; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany., Deelen P; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands.; Genomics Coordination Center, University Medical Centre Groningen, Groningen, the Netherlands.; Department of Genetics, University Medical Centre Utrecht, Utrecht, the Netherlands., Zeng B; School of Biological Sciences, Georgia Tech, Atlanta, GA, USA., Kirsten H; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Saha A; Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA., Kreuzhuber R; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, United Kingdom., Yazar S; Garvan Institute of Medical Research, Garvan-Weizmann Centre for Cellular Genomics, Sydney, New South Wales, Australia., Brugge H; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., Oelen R; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., de Vries DH; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., van der Wijst MGP; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., Kasela S; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Pervjakova N; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Alves I; Computational Biology, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; L'institut du thorax, Université de Nantes, CHU Nantes, INSERM, CNRS, Nantes, France., Favé MJ; Computational Biology, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Agbessi M; Computational Biology, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Christiansen MW; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Jansen R; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute and Amsterdam Neuroscience, Amsterdam, the Netherlands., Seppälä I; Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Tong L; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Schramm K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Munich, Ludwig Maximilian's University, Munich, Germany., Hemani G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom., Verlouw J; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, United Kingdom.; School of Life Sciences, College of Liberal Arts and Science, University of Westminster, London, United Kingdom.; Division of Medical Sciences, Department of Health Sciences, Luleå University of Technology, Luleå, Sweden., Sönmez Flitman R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Brown A; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.; Population Health and Genomics, University of Dundee, Dundee, United Kingdom., Kukushkina V; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kalnapenkis A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Rüeger S; Lausanne University Hospital, Lausanne, Switzerland., Porcu E; Lausanne University Hospital, Lausanne, Switzerland., Kronberg J; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kettunen J; Computational Medicine, Faculty of Medicine, University of Oulu, Oulu, Finland.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Finnish Institute for Health and Welfare, Helsinki, Finland., Lee B; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Zhang F; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Qi T; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Hernandez JA; Garvan Institute of Medical Research, Garvan-Weizmann Centre for Cellular Genomics, Sydney, New South Wales, Australia., Arindrarto W; Leiden University Medical Center, Leiden, the Netherlands., Beutner F; Heart Center Leipzig, Universität Leipzig, Leipzig, Germany., Dmitrieva J; Unit of Animal Genomics, WELBIO, GIGA-R & Faculty of Veterinary Medicine, University of Liège, Liège, Belgium., Elansary M; Unit of Animal Genomics, WELBIO, GIGA-R & Faculty of Veterinary Medicine, University of Liège, Liège, Belgium., Fairfax BP; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Georges M; Unit of Animal Genomics, WELBIO, GIGA-R & Faculty of Veterinary Medicine, University of Liège, Liège, Belgium., Heijmans BT; Leiden University Medical Center, Leiden, the Netherlands., Hewitt AW; Menzies Institute for Medical Research, School of Medicine, University of Tasmania, Hobart, Tasmania, Australia.; Centre for Eye Research Australia, Department of Surgery, University of Melbourne, Melbourne, Victoria, Australia., Kähönen M; Department of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Kim Y; Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA.; Genetics and Genomic Science Department, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Knight JC; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Kovacs P; IFB Adiposity Diseases, Universität Leipzig, Leipzig, Germany., Krohn K; Interdisciplinary Center for Clinical Research, Faculty of Medicine, Universität Leipzig, Leipzig, Germany., Li S; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Genomics Coordination Center, University Medical Centre Groningen, Groningen, the Netherlands., Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Marigorta UM; School of Biological Sciences, Georgia Tech, Atlanta, GA, USA.; Integrative Genomics Lab, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Bizkaia Science and Technology Park, Derio, Spain.; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain., Mei H; Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Momozawa Y; Unit of Animal Genomics, WELBIO, GIGA-R & Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Munich, Ludwig Maximilian's University, Munich, Germany.; IBE, Faculty of Medicine, LMU Munich, Munich, Germany., Nauck M; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Nivard MG; Department of Biological Psychology, Faculty of Behaviour and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands., Penninx BWJH; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute and Amsterdam Neuroscience, Amsterdam, the Netherlands., Pritchard JK; Department of Biology, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland., Rotzschke O; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Slagboom EP; Leiden University Medical Center, Leiden, the Netherlands., Stehouwer CDA; Department of Internal Medicine and School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands., Stumvoll M; Department of Medicine, Universität Leipzig, Leipzig, Germany., Sullivan P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., 't Hoen PAC; Center for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center Nijmegen, Nijmegen, the Netherlands., Thiery J; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute for Laboratory Medicine, LIFE-Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany., Tönjes A; Department of Medicine, Universität Leipzig, Leipzig, Germany., van Dongen J; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute and Amsterdam Neuroscience, Amsterdam, the Netherlands., van Iterson M; Leiden University Medical Center, Leiden, the Netherlands., Veldink JH; UMC Utrecht Brain Center, University Medical Center Utrecht, Department of Neurology, Utrecht University, Utrecht, the Netherlands., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Warmerdam R; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., Wijmenga C; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Swertz M; Genomics Coordination Center, University Medical Centre Groningen, Groningen, the Netherlands., Andiappan A; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Montgomery GW; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Ripatti S; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.; Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Perola M; National Institute for Health and Welfare, University of Helsinki, Helsinki, Finland., Kutalik Z; Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland., Dermitzakis E; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.; Institute of Genetics and Genomics in Geneva (iGE3), University of Geneva, Geneva, Switzerland., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Frayling T; Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, United Kingdom., van Meurs J; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Prokisch H; Institute of Neurogenomics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technical University Munich, Munich, Germany., Ahsan H; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA., Pierce BL; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Boomsma DI; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute and Amsterdam Neuroscience, Amsterdam, the Netherlands., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA., Gharib SA; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA., Awadalla P; Computational Biology, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Milani L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Ouwehand WH; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom.; Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom., Downes K; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom., Stegle O; Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, United Kingdom.; Division of Computational Genomics and Systems Genetics, German Cancer Research Center, Heidelberg, Germany., Battle A; Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Visscher PM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Yang J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Powell J; Garvan Institute of Medical Research, Garvan-Weizmann Centre for Cellular Genomics, Sydney, New South Wales, Australia.; UNSW Cellular Genomics Futures Institute, University of New South Wales, Sydney, New South Wales, Australia., Gibson G; School of Biological Sciences, Georgia Tech, Atlanta, GA, USA., Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Franke L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. lude@ludesign.nl.; Oncode Institute, Amsterdam, the Netherlands. lude@ludesign.nl.
Publikováno v:
Nature genetics [Nat Genet] 2021 Sep; Vol. 53 (9), pp. 1300-1310. Date of Electronic Publication: 2021 Sep 02.
Autor:
Wuttke M; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.; Renal Division, Department of Medicine IV, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Li Y; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Li M; Division of Nephrology and Hypertension, Department of Medicine, University of Utah, Salt Lake City, USA., Sieber KB; Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Gorski M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Tin A; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Welch Center for Prevention, Epidemiology and Clinical Research, Baltimore, MD, USA., Wang L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Chu AY; Genetics, Merck & Co., Inc, Kenilworth, NJ, USA., Hoppmann A; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Kirsten H; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Giri A; Division of Quantitative Sciences, Department of Obstetrics & Gynecology, Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA.; Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Chai JF; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Sveinbjornsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Tayo BO; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA., Nutile T; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy., Fuchsberger C; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Cocca M; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Ghasemi S; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Xu Y; Division of Nephrology and Hypertension, Department of Medicine, University of Utah, Salt Lake City, USA., Horn K; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Noce D; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sedaghat S; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Yu Z; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Afaq S; Department of Epidemiology and Biostatistics, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.; Institute of Public Health & Social Sciences, Khyber Medical University, Peshawar, Pakistan., Ahluwalia TS; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Almgren P; Diabetes and Cardiovascular Disease-Genetic Epidemiology, Department of Clincial Sciences in Malmö, Lund University, Malmö, Sweden., Amin N; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Ärnlöv J; Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; School of Health and Social Studies, Dalarna University, Stockholm, Sweden., Bakker SJL; Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Bansal N; Division of Nephrology, University of Washington, Seattle, WA, USA.; Kidney Research Institute, University of Washington, Seattle, WA, USA., Baptista D; Cardiology, Geneva University Hospitals, Geneva, Switzerland., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa., Biggs ML; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA., Biino G; Institute of Molecular Genetics, National Research Council of Italy, Pavia, Italy., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boerwinkle E; Human Genetics Center, University of Texas Health Science Center, Houston, TX, USA., Boissel M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Digital Health Center, Hasso Plattner Institute and University of Potsdam, Potsdam, Germany., Boutin TS; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany., Brumat M; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Burkhardt R; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Campana E; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Campbell A; Center for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Campbell H; Center for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Canouil M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Carroll RJ; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Catamo E; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Chambers JC; Department of Epidemiology and Biostatistics, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK., Chee ML; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore., Chee ML; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore., Chen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Cheng Y; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Christensen K; Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, Southern Denmark University, Odense, Denmark., Cifkova R; Center for Cardiovascular Prevention, Charles University in Prague, First Faculty of Medicine and Thomayer Hospital, Prague, Czech Republic.; Department of Medicine II, Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic., Ciullo M; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Italy., Concas MP; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Coresh J; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Corre T; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland., Sala CF; San Raffaele Research Institute, Milan, Italy., Cusi D; Institute of Biomedical Technologies, National Research Council of Italy, Milan, Italy.; Bio4Dreams-Business Nursery for Life Sciences, Milan, Italy., Danesh J; Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Daw EW; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., de Borst MH; Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., De Grandi A; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., de Vries APJ; Section of Nephrology, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands., Degenhardt F; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany., Delgado G; Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Demirkan A; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Di Angelantonio E; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, Cambridge, UK., Dittrich K; Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Center for Pediatric Research, University of Leipzig, Leipzig, Germany., Divers J; Public Health Sciences-Biostatistics, Wake Forest School of Medicine, Winston-Salem, NC, USA., Dorajoo R; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore., Eckardt KU; Intensive Care Medicine, Charité, Berlin, Germany.; Department of Nephrology and Hypertension, Friedrich Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany., Ehret G; Cardiology, Geneva University Hospitals, Geneva, Switzerland., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK.; Imperial College NIHR Biomedical Research Center, Imperial College London, London, UK.; Dementia Research Institute, Imperial College London, London, UK.; Health Data Research UK-London, London, UK., Endlich K; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany., Evans MK; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Baltimore, MD, USA., Felix JF; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Foo VHX; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore., Franco OH; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany., Freedman BI; Section on Nephrology, Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA., Freitag-Wolf S; Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, Kiel, Germany., Friedlander Y; School of Public Health and Community Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Froguel P; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France.; Department of Genomics of Common Disease, Imperial College London, London, UK., Gansevoort RT; Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Gao H; Department of Epidemiology and Biostatistics, MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK., Gasparini P; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Gaziano JM; Massachusetts Veterans Epidemiology Research and Information Center, VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA., Giedraitis V; Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Girotto G; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gögele M; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy., Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Gudbjartsson DF; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Haller T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Hamet P; Montreal University Hospital Research Center, CHUM, Montreal, Quebec, Canada.; Medpharmgene, Montreal, Quebec, Canada., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, MD, USA., Hartman CA; Interdisciplinary Center of Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Hellwege JN; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore., Hicks AA; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Huang W; Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center, Shanghai, China.; Shanghai Industrial Technology Institute, Shanghai, China., Hutri-Kähönen N; Department of Pediatrics, Tampere University Hospital, Tampere, Finland.; Department of Pediatrics, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Hwang SJ; NHLBI's Framingham Heart Study, Framingham, MA, USA.; The Center for Population Studies, NHLBI, Framingham, MA, USA., Ikram MA; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Indridason OS; Division of Nephrology, Internal Medicine Services, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland., Ingelsson E; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Ising M; Max Planck Institute of Psychiatry, Munich, Germany., Jaddoe VWV; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Jakobsdottir J; The Center of Public Health Sciences, University of Iceland, Reykjavík, Iceland., Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany.; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Joshi PK; Center for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Josyula NS; Geisinger Research, Biomedical and Translational Informatics Institute, Rockville, MD, USA., Jung B; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Kyoto-McGill International Collaborative School in Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Kammerer CM; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Kanai M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Kastarinen M; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Khor CC; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore., Kiess W; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Center for Pediatric Research, University of Leipzig, Leipzig, Germany., Kleber ME; Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Koenig W; Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.; Institute of Epidemiology and Biostatistics, University of Ulm, Ulm, Germany., Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Körner A; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Center for Pediatric Research, University of Leipzig, Leipzig, Germany., Kovacs P; Integrated Research and Treatment Center Adiposity Diseases, University of Leipzig, Leipzig, Germany., Kraja AT; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Krajcoviechova A; Center for Cardiovascular Prevention, Charles University in Prague, First Faculty of Medicine and Thomayer Hospital, Prague, Czech Republic.; Department of Medicine II, Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic., Kramer H; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA.; Division of Nephrology and Hypertension, Loyola University Chicago, Chicago, IL, USA., Krämer BK; Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Kronenberg F; Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Kubo M; RIKEN Center for Integrative Medical Sciences (IMS), Yokohama (Kanagawa), Japan., Kühnel B; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Kuokkanen M; The Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.; Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland., Kuusisto J; Department of Medicine, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., La Bianca M; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Laakso M; Department of Medicine, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Lange LA; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO, USA., Langefeld CD; Public Health Sciences-Biostatistics, Wake Forest School of Medicine, Winston-Salem, NC, USA., Lee JJ; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Lehne B; Department of Epidemiology and Biostatistics, Faculty of Medicine, School of Public Health, Imperial College London, London, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Lieb W; Institute of Epidemiology and Biobank Popgen, Kiel University, Kiel, Germany., Lim SC; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Diabetes Center, Khoo Teck Puat Hospital, Singapore, Singapore., Lind L; Cardiovascular Epidemiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Lindgren CM; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Liu J; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Liu J; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lucae S; Max Planck Institute of Psychiatry, Munich, Germany., Lukas MA; Target Sciences-Genetics, GlaxoSmithKline, Albuquerque, NM, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Mägi R; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Mahajan A; Wellcome Trust Center for Human Genetics, University of Oxford, Oxford, UK.; Oxford Center for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Martins J; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany., März W; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Medical Clinic V, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Mascalzoni D; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy., Matsuda K; Laboratory of Clinical Genome Sequencing, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Meisinger C; Independent Research Group Clinical Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Epidemiology, Ludwig- Maximilians-Universität München at UNIKA-T Augsburg, Augsburg, Germany., Meitinger T; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Melander O; Hypertension and Cardiovascular Disease, Department of Clincial Sciences Malmö, Lund University, Malmö, Sweden., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Mikaelsdottir EK; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Milaneschi Y; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands., Miliku K; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Mishra PP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Mononen N; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Montgomery GW; Institute for Molecular Bioscience, University of Queensland, St Lucia, Queensland, Australia., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Mychaleckyj JC; Center for Public Health Genomics, University of Virginia, Charlottesville, Charlottesville, VA, USA., Nadkarni GN; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., Nauck M; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, Finland.; Department of Cardiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, Tampere University, Tampere, Finland., Ning B; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Noordam R; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands., O'Connell J; University of Maryland School of Medicine, Baltimore, MD, USA., O'Donoghue ML; Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA.; TIMI Study Group, Boston, MA, USA., Olafsson I; Department of Clinical Biochemistry, Landspitali University Hospital, Reykjavik, Iceland., Oldehinkel AJ; Interdisciplinary Center of Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Orho-Melander M; Diabetes and Cardiovascular Disease-Genetic Epidemiology, Department of Clincial Sciences in Malmö, Lund University, Malmö, Sweden., Ouwehand WH; Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Palmer ND; Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Palsson R; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Division of Nephrology, Internal Medicine Services, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland., Penninx BWJH; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands., Perls T; Department of Medicine, Geriatrics Section, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA., Perola M; National Institute for Health and Welfare, Helsinki, Finland., Pirastu M; Institute of Genetic and Biomedical Research, National Research Council of Italy, UOS of Sassari, Li Punti, Sassari, Italy., Pirastu N; Center for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Pistis G; Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland., Podgornaia AI; Genetics, Merck & Co., Inc, Kenilworth, NJ, USA., Polasek O; Faculty of Medicine, University of Split, Split, Croatia.; Gen-info Ltd, Zagreb, Croatia., Ponte B; Service de Néphrologie, Geneva University Hospitals, Geneva, Switzerland., Porteous DJ; Center for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Center for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Poulain T; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Pramstaller PP; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy., Preuss MH; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Prins BP; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Rabelink TJ; Section of Nephrology, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.; Einthoven Laboratory of Experimental Vascular Research, Leiden University Medical Center, Leiden, the Netherlands., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Reilly DF; Genetics, Merck & Co., Inc, Kenilworth, NJ, USA., Rettig R; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rheinberger M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Rivadeneira F; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Rizzi F; Department of Health Sciences, University of Milan, Milano, Italy.; ePhood Scientific Unit, ePhood SRL, Milano, Italy., Roberts DJ; NHS Blood and Transplant, BRC Oxford Haematology Theme; Nuffield Division of Clinical Laboratory Sciences; University of Oxford, Oxford, UK., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Rossing P; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Rudan I; Center for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ruggiero D; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Italy., Ryan KA; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA., Saba Y; Molecular Biology and Biochemistry, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Salvi E; Department of Health Sciences, University of Milan, Milano, Italy.; Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Milan, Italy., Saum KU; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Schmidt H; Institute of Molecular Biology and Biochemistry, Center for Molecular Medicine, Medical University of Graz, Graz, Austria., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Schöttker B; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany., Schulz CA; Diabetes and Cardiovascular Disease-Genetic Epidemiology, Department of Clincial Sciences in Malmö, Lund University, Malmö, Sweden., Schupf N; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, USA., Shaffer CM; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Shi Y; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore., Smith AV; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Soranzo N; Human Genetics, Wellcome Sanger Institute, Hinxton, UK., Spracklen CN; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, Ludwig-Maximilians-Universität München, München, Germany., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Stumvoll M; Department of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany., Svensson PO; Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.; Department of Cardiology, Södersjukhuset, Stockholm, Sweden., Szymczak S; Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, Kiel, Germany., Tai ES; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Tajuddin SM; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Baltimore, MD, USA., Tan NYQ; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Teren A; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Heart Center Leipzig, Leipzig, Germany., Tham YC; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore., Thiery J; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany., Thio CHL; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Thomsen H; Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Toniolo D; San Raffaele Research Institute, Milan, Italy., Tönjes A; Department of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany., Tremblay J; Montreal University Hospital Research Center, CHUM, Montreal, Quebec, Canada.; CRCHUM, Montreal, Canada., Tzoulaki I; Department of Epidemiology and Biostatistics, MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Uitterlinden AG; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Vaccargiu S; Institute of Genetic and Biomedical Research, National Research Council of Italy, UOS of Sassari, Li Punti, Sassari, Italy., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Durrer Center for Cardiovascular Research, The Netherlands Heart Institute, Utrecht, the Netherlands., van Duijn CM; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Velez Edward DR; Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Vogelezang S; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Völker U; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Vollenweider P; Internal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland., Waeber G; Internal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany., Wallentin L; Cardiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Wang YX; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wang C; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Waterworth DM; Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA., Bin Wei W; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China., White H; Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand., Whitfield JB; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Wild SH; Center for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Wilson JF; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Center for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Wojczynski MK; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Wong C; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Wong TY; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Xu L; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Yasuda M; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan., Yerges-Armstrong LM; Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA., Zhang W; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK., Zonderman AB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Baltimore, MD, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.; Department of Medicine, Harbor-UCLA Medical Center, Torrance, CA, USA., Bochud M; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, Department of Epidemiology, Department of Health Service, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Dehghan A; Department of Epidemiology and Biostatistics, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.; Department of Epidemiology and Biostatistics, MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK., Parsa A; Division of Kidney, Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Ho K; Kidney Health Research Institute (KHRI), Geisinger, Danville, PA, USA.; Department of Nephrology, Geisinger, Danville, PA, USA., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Trust Center for Human Genetics, University of Oxford, Oxford, UK., Devuyst O; Institute of Physiology, University of Zurich, Zurich, Switzerland., Akilesh S; Kidney Research Institute, University of Washington, Seattle, WA, USA.; Anatomic Pathology, University of Washington Medical Center, Seattle, WA, USA., Pendergrass SA; Geisinger Research, Biomedical and Translational Informatics Institute, Danville, PA, USA., Sim X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.; Department of Nephrology and Rheumatology, Kliniken Südostbayern, Regensburg, Germany., Okada Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Osaka, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan., Edwards TL; Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Hung AM; Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Vanderbilt University Medical Center, Division of Nephrology & Hypertension, Nashville, TN, USA., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Köttgen A; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany. anna.koettgen@uniklinik-freiburg.de.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. anna.koettgen@uniklinik-freiburg.de., Pattaro C; Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy. cristian.pattaro@eurac.edu.
Publikováno v:
Nature genetics [Nat Genet] 2019 Jun; Vol. 51 (6), pp. 957-972. Date of Electronic Publication: 2019 May 31.
Autor:
Ji SG; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Juran BD; Center for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA., Mucha S; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Folseraas T; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Jostins L; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Christ Church, University of Oxford, St Aldates, Oxford, UK., Melum E; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Kumasaka N; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Atkinson EJ; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA., Schlicht EM; Center for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA., Liu JZ; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Shah T; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Gutierrez-Achury J; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Boberg KM; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Gastroenterology, Department of Transplantation Medicine, Division of Cancer, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Bergquist A; Department of Gastroenterology and Hepatology, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden., Vermeire S; Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium.; Department of Gastroenterology, University Hospital Leuven, Leuven, Belgium., Eksteen B; Snyder Institute for Chronic Diseases, Department of Medicine, University of Calgary, Calgary, Alberta, Canada., Durie PR; Physiology and Experimental Medicine, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada., Farkkila M; Helsinki University and Helsinki University Hospital, Clinic of Gastroenterology, Helsinki, Finland., Müller T; Department of Internal Medicine, Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Berlin, Germany., Schramm C; 1st Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Sterneck M; Department of Hepatobiliary Surgery and Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Weismüller TJ; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.; Integrated Research and Treatment Center-Transplantation (IFB-tx), Hannover Medical School, Hannover, Germany.; Department of Internal Medicine 1, University Hospital of Bonn, Bonn, Germany., Gotthardt DN; Department of Medicine, University Hospital of Heidelberg, Heidelberg, Germany., Ellinghaus D; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Braun F; Department of General, Visceral, Thoracic, Transplantation and Pediatric Surgery, University Medical Centre Schleswig-Holstein, Campus Kiel, Kiel, Germany., Teufel A; Department of Medicine I, University Medical Center, Regensburg, Germany., Laudes M; Clinic of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany., Lieb W; Institute of Epidemiology and Biobank PopGen, University Hospital Schleswig-Holstein, Kiel, Germany., Jacobs G; Institute of Epidemiology and Biobank PopGen, University Hospital Schleswig-Holstein, Kiel, Germany., Beuers U; Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Wijmenga C; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Marschall HU; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Milkiewicz P; Liver and Internal Medicine Unit, Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland., Pares A; Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, University of Barcelona, Barcelona, Spain., Kontula K; Department of Medicine, University of Helsinki, Helsinki, Finland., Chazouillères O; AP-HP Hôpital Saint Antoine, Department of Hepatology, UPMC University Paris 6, Paris, France., Invernizzi P; Center for Autoimmune Liver Diseases, Humanitas Clinical and Research Center, Rozzano, Milan, Italy., Goode E; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Spiess K; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Moore C; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Sambrook J; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Hematology, University of Cambridge, Cambridge, UK., Ouwehand WH; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Hematology, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, Cambridge, UK., Roberts DJ; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant-Oxford Centre, John Radcliffe Hospital, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Danesh J; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Floreani A; Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, Padova, Italy., Gulamhusein AF; Center for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA., Eaton JE; Center for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA., Schreiber S; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.; Department for General Internal Medicine, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany., Coltescu C; Liver Centre, Toronto Western Hospital, Toronto, Ontario, Canada., Bowlus CL; Division of Gastroenterology and Hepatology, University of California at Davis, Davis, California, USA., Luketic VA; Gastroenterology and Hepatology Section, Virginia Commonwealth University, Richmond, Virginia, USA., Odin JA; Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA., Chopra KB; Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Kowdley KV; Liver Care Network and Organ Care Research, Swedish Medical Center, Seattle, Washington, USA., Chalasani N; Indiana University School of Medicine, Indianapolis, Indiana, USA., Manns MP; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.; Integrated Research and Treatment Center-Transplantation (IFB-tx), Hannover Medical School, Hannover, Germany., Srivastava B; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Mells G; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK.; Division of Gastroenterology and Hepatology, Addenbrooke's Hospital, Cambridge, UK., Sandford RN; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Alexander G; Department of Medicine, Division of Hepatology, University of Cambridge, Cambridge, UK., Gaffney DJ; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Chapman RW; Department of Translational Gastroenterology, Oxford University Hospitals NHS Trust, Oxford, UK., Hirschfield GM; Centre for Liver Research, NIHR Biomedical Research Unit, University of Birmingham, Birmingham, UK.; University of Toronto and Liver Center, Toronto Western Hospital, Toronto, Ontario, Canada., de Andrade M; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA., Rushbrook SM; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Franke A; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Karlsen TH; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Gastroenterology, Department of Transplantation Medicine, Division of Cancer, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Lazaridis KN; Center for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA., Anderson CA; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
Publikováno v:
Nature genetics [Nat Genet] 2017 Feb; Vol. 49 (2), pp. 269-273. Date of Electronic Publication: 2016 Dec 19.
Autor:
Sifrim A; Wellcome Trust Sanger Institute, Cambridge, UK., Hitz MP; Wellcome Trust Sanger Institute, Cambridge, UK.; Department of Congenital Heart Disease and Pediatric Cardiology, Universitätsklinikum Schleswig-Holstein Kiel, Kiel, Germany.; German Center for Cardiovascular Research (DZHK), Berlin, Germany., Wilsdon A; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK., Breckpot J; Center for Human Genetics, University Hospitals Leuven, Leuven, Belgium., Turki SH; Wellcome Trust Sanger Institute, Cambridge, UK.; Department of Pathology, King Abdulaziz Medical City, Riyadh, Saudi Arabia.; Genetics Training Program, Harvard Medical School, Boston, Massachusetts, USA., Thienpont B; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium., McRae J; Wellcome Trust Sanger Institute, Cambridge, UK., Fitzgerald TW; Wellcome Trust Sanger Institute, Cambridge, UK., Singh T; Wellcome Trust Sanger Institute, Cambridge, UK., Swaminathan GJ; Wellcome Trust Sanger Institute, Cambridge, UK., Prigmore E; Wellcome Trust Sanger Institute, Cambridge, UK., Rajan D; Wellcome Trust Sanger Institute, Cambridge, UK., Abdul-Khaliq H; Department of Pediatric Cardiology, Saarland University, Homburg, Germany.; Competence Network for Congenital Heart Defects, National Register for Congenital Heart Defects, DZHK, Berlin, Germany., Banka S; Manchester Centre for Genomic Medicine, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.; Manchester Centre for Genomic Medicine, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Bauer UM; Competence Network for Congenital Heart Defects, National Register for Congenital Heart Defects, DZHK, Berlin, Germany., Bentham J; Department of Paediatric Cardiology, Yorkshire Heart Centre, Leeds, UK., Berger F; German Center for Cardiovascular Research (DZHK), Berlin, Germany.; Competence Network for Congenital Heart Defects, National Register for Congenital Heart Defects, DZHK, Berlin, Germany.; Department of Congenital Heart Disease and Pediatric Cardiology, German Heart Institute Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany., Bhattacharya S; Department of Cardiovascular Medicine, University of Oxford, Oxford, UK., Bu'Lock F; East Midlands Congenital Heart Centre, Glenfield Hospital, Leicester, UK., Canham N; North West Thames Regional Genetics Centre, London North West Healthcare NHS Trust, Harrow, UK., Colgiu IG; Wellcome Trust Sanger Institute, Cambridge, UK., Cosgrove C; Department of Cardiovascular Medicine, University of Oxford, Oxford, UK., Cox H; West Midlands Regional Genetics Service, Birmingham Women's NHS Foundation Trust, Birmingham Women's Hospital, Birmingham, UK., Daehnert I; Competence Network for Congenital Heart Defects, National Register for Congenital Heart Defects, DZHK, Berlin, Germany.; Department of Pediatric Cardiology, Heart Center, University of Leipzig, Leipzig, Germany., Daly A; Wellcome Trust Sanger Institute, Cambridge, UK., Danesh J; Wellcome Trust Sanger Institute, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Fryer A; Department of Clinical Genetics, Liverpool Women's NHS Foundation Trust, Liverpool, UK., Gewillig M; Department of Pediatric Cardiology, University Hospitals Leuven, Leuven, Belgium., Hobson E; Yorkshire Regional Genetics Service, Leeds Teaching Hospitals NHS Trust, Department of Clinical Genetics, Chapel Allerton Hospital, Leeds, UK., Hoff K; Department of Congenital Heart Disease and Pediatric Cardiology, Universitätsklinikum Schleswig-Holstein Kiel, Kiel, Germany.; German Center for Cardiovascular Research (DZHK), Berlin, Germany., Homfray T; South West Thames Regional Genetics Centre, St George's Healthcare NHS Trust, University of London, London, UK., Kahlert AK; Department of Congenital Heart Disease and Pediatric Cardiology, Universitätsklinikum Schleswig-Holstein Kiel, Kiel, Germany.; German Center for Cardiovascular Research (DZHK), Berlin, Germany.; Institute for Clinical Genetics, Carl Gustav Carus Faculty of Medicine, Dresden, Germany., Ketley A; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK., Kramer HH; Department of Congenital Heart Disease and Pediatric Cardiology, Universitätsklinikum Schleswig-Holstein Kiel, Kiel, Germany.; German Center for Cardiovascular Research (DZHK), Berlin, Germany.; Competence Network for Congenital Heart Defects, National Register for Congenital Heart Defects, DZHK, Berlin, Germany., Lachlan K; Wessex Clinical Genetics Service, University Hospital Southampton, Princess Anne Hospital, Southampton, UK.; Wessex Regional Genetics Laboratory, Salisbury NHS Foundation Trust, Salisbury District Hospital, Salisbury, UK.; Faculty of Medicine, University of Southampton, Southampton, UK., Lampe AK; South East of Scotland Clinical Genetic Service, IGMM North, Western General Hospital, Edinburgh, UK., Louw JJ; Department of Pediatric Cardiology, University Hospitals Leuven, Leuven, Belgium., Manickara AK; Hospital for Sick Children, Toronto, Ontario, Canada., Manase D; Hospital for Sick Children, Toronto, Ontario, Canada., McCarthy KP; Cardiac Morphology Unit, Royal Brompton Hospital and the National Heart and Lung Institute, Imperial College, UK., Metcalfe K; Manchester Centre for Genomic Medicine, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Moore C; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Newbury-Ecob R; Department of Clinical Genetics, St Michael's Hospital, Bristol, UK., Omer SO; Division of Pediatric Cardiology, King Abdulaziz Cardiac Center, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Ouwehand WH; Wellcome Trust Sanger Institute, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, Cambridge, UK., Park SM; East Anglian Medical Genetics Service, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, UK., Parker MJ; Sheffield Children's Hospital NHS Foundation Trust, Western Bank, Sheffield, UK., Pickardt T; Competence Network for Congenital Heart Defects, National Register for Congenital Heart Defects, DZHK, Berlin, Germany., Pollard MO; Wellcome Trust Sanger Institute, Cambridge, UK., Robert L; South East Thames Regional Genetics Centre, Guy's and St Thomas' NHS Foundation Trust, Guy's Hospital, London, UK., Roberts DJ; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Sambrook J; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Setchfield K; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK., Stiller B; Competence Network for Congenital Heart Defects, National Register for Congenital Heart Defects, DZHK, Berlin, Germany.; Department of Congenital Heart Defects and Pediatric Cardiology, Heart Centre, University of Freiburg, Freiburg, Germany., Thornborough C; East Midlands Congenital Heart Centre, Glenfield Hospital, Leicester, UK., Toka O; Competence Network for Congenital Heart Defects, National Register for Congenital Heart Defects, DZHK, Berlin, Germany.; Friedrich Alexander Universität Erlangen-Nürnberg (FAU), Department of Pediatric Cardiology, Erlangen, Germany., Watkins H; Department of Cardiovascular Medicine, University of Oxford, Oxford, UK., Williams D; West Midlands Regional Genetics Service, Birmingham Women's NHS Foundation Trust, Birmingham Women's Hospital, Birmingham, UK., Wright M; Northern Genetics Service, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Institute of Human Genetics, International Centre for Life, Newcastle-upon-Tyne, UK., Mital S; Hospital for Sick Children, Toronto, Ontario, Canada., Daubeney PE; Division of Paediatric Cardiology, Royal Brompton Hospital, London, UK.; Paediatric Cardiology, Imperial College, London, UK., Keavney B; Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK., Goodship J; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Abu-Sulaiman RM; Division of Pediatric Cardiology, King Abdulaziz Cardiac Center, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia., Klaassen S; German Center for Cardiovascular Research (DZHK), Berlin, Germany.; Competence Network for Congenital Heart Defects, National Register for Congenital Heart Defects, DZHK, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), Charité Medical Faculty and Max Delbruck Center for Molecular Medicine, Berlin, Germany.; Department of Pediatric Cardiology, Charité University Medicine, Berlin, Germany., Wright CF; Wellcome Trust Sanger Institute, Cambridge, UK., Firth HV; East Anglian Medical Genetics, Cambridge University Hospitals NHS Foundation Trust, Biomedical Campus, Cambridge, UK., Barrett JC; Wellcome Trust Sanger Institute, Cambridge, UK., Devriendt K; Center for Human Genetics, University Hospitals Leuven, Leuven, Belgium., FitzPatrick DR; Medical Research Council (MRC) Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Western General Hospital, Edinburgh, UK., Brook JD; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK., Hurles ME; Wellcome Trust Sanger Institute, Cambridge, UK.
Publikováno v:
Nature genetics [Nat Genet] 2016 Sep; Vol. 48 (9), pp. 1060-5. Date of Electronic Publication: 2016 Aug 01.
Autor:
Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Esko T; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [3] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [4] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA., Yang J; 1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. [2] University of Queensland Diamantina Institute, Translation Research Institute, Brisbane, Queensland, Australia., Vedantam S; 1] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA., Pers TH; 1] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [3] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA. [4] Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark., Gustafsson S; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden., Chu AY; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Estrada K; 1] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [2] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [3] Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Luan J; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Kutalik Z; 1] Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland. [2] Swiss Institute of Bioinformatics, Lausanne, Switzerland. [3] Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Buchkovich ML; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Croteau-Chonka DC; 1] Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA. [2] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Day FR; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Duan Y; Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA., Fall T; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden. [3] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Fehrmann R; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Jackson AU; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Karjalainen J; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Lo KS; Montreal Heart Institute, Montreal, Quebec, Canada., Locke AE; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Mägi R; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Mihailov E; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Porcu E; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Italy., Randall JC; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Wellcome Trust Sanger Institute, Hinxton, UK., Scherag A; 1] Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany. [2] Clinical Epidemiology, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany., Vinkhuyzen AA; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Westra HJ; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Winkler TW; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany., Workalemahu T; Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA., Zhao JH; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Absher D; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA., Albrecht E; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Anderson D; Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia., Baron J; Section on Growth and Development, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, US National Institutes of Health, Bethesda, Maryland, USA., Beekman M; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Demirkan A; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands. [2] Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Ehret GB; 1] Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. [2] Department of Specialties of Internal Medicine, Division of Cardiology, Geneva University Hospital, Geneva, Switzerland., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Feitosa MF; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Fischer K; Estonian Genome Center, University of Tartu, Tartu, Estonia., Fraser RM; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Goel A; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK., Gong J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Justice AE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Kleber ME; 1] Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany. [2] Department of Internal Medicine II, Ulm University Medical Centre, Ulm, Germany., Kristiansson K; National Institute for Health and Welfare, Helsinki, Finland., Lim U; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Lotay V; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Lui JC; Section on Growth and Development, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, US National Institutes of Health, Bethesda, Maryland, USA., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Mateo Leach I; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Medina-Gomez C; 1] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [2] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [3] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Nyholt DR; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Palmer CD; 1] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA., Pasko D; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Pechlivanis S; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany., Prokopenko I; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. [3] Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK., Ried JS; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Ripke S; 1] Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA., Shungin D; 1] Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hospital, Malmö, Sweden. [2] Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden. [3] Department of Odontology, Umeå University, Umeå, Sweden., Stancáková A; Department of Medicine, University of Eastern Finland, Kuopio, Finland., Strawbridge RJ; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, USA., Teumer A; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Trompet S; 1] Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., van der Laan SW; Experimental Cardiology Laboratory, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., van Setten J; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wang Z; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany. [3] Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA. [4] Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA., Yengo L; 1] CNRS UMR 8199, Lille, France. [2] European Genomic Institute for Diabetes, Lille, France. [3] Université de Lille 2, Lille, France., Zhang W; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Afzal U; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Arnlöv J; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden. [3] School of Health and Social Studies, Dalarna University, Falun, Sweden., Arscott GM; PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia, Australia., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy., Barrett A; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Bellis C; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA., Bennett AJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Berne C; Department of Medical Sciences, Endocrinology, Diabetes and Metabolism, Uppsala University, Uppsala, Sweden., Blüher M; 1] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany. [2] Department of Medicine, University of Leipzig, Leipzig, Germany., Bolton JL; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Böttcher Y; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany., Boyd HA; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Bruinenberg M; LifeLines, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland., Buyske S; 1] Department of Statistics and Biostatistics, Rutgers University, Piscataway, New Jersy, USA. [2] Department of Genetics, Rutgers University, Piscataway, New Jersey, USA., Caspersen IH; Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway., Chines PS; Genome Technology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Clarke R; Clinical Trial Service Unit, Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Claudi-Boehm S; Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, Ulm, Germany., Cooper M; Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia., Daw EW; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., De Jong PA; Department of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands., Deelen J; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Delgado G; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany., Denny JC; Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA., Dhonukshe-Rutten R; Department of Human Nutrition, Wageningen University, Wageningen, the Netherlands., Dimitriou M; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece., Doney AS; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Dörr M; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Eklund N; 1] National Institute for Health and Welfare, Helsinki, Finland. [2] Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland., Eury E; 1] CNRS UMR 8199, Lille, France. [2] European Genomic Institute for Diabetes, Lille, France. [3] Université de Lille 2, Lille, France., Folkersen L; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Garcia ME; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Go AS; Kaiser Permanente, Division of Research, Oakland, California, USA., Grallert H; 1] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [3] German Center for Diabetes Research (DZD), Neuherberg, Germany., Grammer TB; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany., Gräßler J; Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Grönberg H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., de Groot LC; Department of Human Nutrition, Wageningen University, Wageningen, the Netherlands., Groves CJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Haller T; Estonian Genome Center, University of Tartu, Tartu, Estonia., Hallmans G; Unit of Nutritional Research, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Hannemann A; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Heard-Costa NL; 1] National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, USA. [2] Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA., Helmer Q; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands. [3] Faculty of Psychology and Education, VU University Amsterdam, Amsterdam, the Netherlands., Hemani G; 1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. [2] University of Queensland Diamantina Institute, Translation Research Institute, Brisbane, Queensland, Australia., Henders AK; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Hillege HL; 1] Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. [2] Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Hlatky MA; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Hoffmann W; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Hoffmann P; 1] Department of Biomedicine, Division of Medical Genetics, University of Basel, Basel, Switzerland. [2] Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany. [3] Institute of Human Genetics, University of Bonn, Bonn, Germany., Holmen O; Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway., Houwing-Duistermaat JJ; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Illig T; 1] Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Isaacs A; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands. [2] Center for Medical Systems Biology, Leiden, the Netherlands., James AL; 1] Department of Pulmonary Physiology and Sleep Medicine, Nedlands, Western Australia, Australia. [2] School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia., Jeff J; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Johansen B; Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway., Johansson Å; Department of Immunology, Genetics and Pathology, SciLifeLab, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden., Jolley J; 1] Department of Haematology, University of Cambridge, Cambridge, UK. [2] NHS Blood and Transplant, Cambridge, UK., Juliusdottir T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Junttila J; Department of Medicine, University of Oulu, Oulu, Finland., Kho AN; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Kinnunen L; National Institute for Health and Welfare, Helsinki, Finland., Klopp N; 1] Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Kocher T; Unit of Periodontology, Department of Restorative Dentistry, Periodontology and Endodontology, University Medicine Greifswald, Greifswald, Germany., Kratzer W; Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindström J; National Institute for Health and Welfare, Helsinki, Finland., Lobbens S; 1] CNRS UMR 8199, Lille, France. [2] European Genomic Institute for Diabetes, Lille, France. [3] Université de Lille 2, Lille, France., Lorentzon M; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Lu Y; 1] Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [2] Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Lyssenko V; Steno Diabetes Center A/S, Gentofte Denmark., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Maillard M; Service of Nephrology, Department of Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., McArdle WL; School of Social and Community Medicine, University of Bristol, Bristol, UK., McKenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Kingston, Jamaica., McLachlan S; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., McLaren PJ; 1] Global Health Institute, Department of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. [2] Institute of Microbiology, University Hospital and University of Lausanne, Lausanne, Switzerland., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Merger S; Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, Ulm, Germany., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Moayyeri A; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Monda KL; 1] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [2] Center for Observational Research, Amgen, Inc., Thousand Oaks, California, USA., Morken MA; Genome Technology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Müller G; Center for Evidence-Based Healthcare, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Müller-Nurasyid M; 1] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Department of Medicine I, University Hospital Großhadern, Ludwig Maximilians Universität, Munich, Germany. [3] Chair of Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians Universität, Neuherberg, Germany. [4] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany., Musk AW; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia., Narisu N; Genome Technology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Nauck M; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Nolte IM; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Nöthen MM; 1] Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany. [2] Institute of Human Genetics, University of Bonn, Bonn, Germany., Oozageer L; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Pilz S; 1] Department of Epidemiology and Biostatistics, Institute for Research in Extramural Medicine (EMGO) Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands. [2] Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria., Rayner NW; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Wellcome Trust Sanger Institute, Hinxton, UK. [3] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Renstrom F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hospital, Malmö, Sweden., Robertson NR; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Roussel R; 1] Diabetology-Endocrinology-Nutrition, Public Hospital System of the City of Paris (AP-HP), Bichat Hospital, Paris, France. [2] INSERM U872, Centre de Recherche des Cordeliers, Paris, France. [3] Paris Diderot University, Paris, France., Sanna S; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Italy., Scharnagl H; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Scholtens S; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Schumacher FR; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Schunkert H; 1] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany. [2] Deutsches Herzzentrum München, Technische Universität München, Munich, Germany., Scott RA; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Sehmi J; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Seufferlein T; Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany., Shi J; National Cancer Institute, Bethesda, Maryland, USA., Silventoinen K; Department of Sociology, University of Helsinki, Helsinki, Finland., Smit JH; 1] EMGO Institute for Health and Care Research, VU University, Amsterdam, the Netherlands. [2] Department of Psychiatry, Neuroscience Campus, VU University Amsterdam, Amsterdam, the Netherlands., Smith AV; 1] Icelandic Heart Association, Kopavogur, Iceland. [2] University of Iceland, Reykjavik, Iceland., Smolonska J; 1] Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. [2] Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Stanton AV; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Stirrups K; 1] Wellcome Trust Sanger Institute, Hinxton, UK. [2] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Stringham HM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Sundström J; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Swertz MA; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Syvänen AC; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Medicine, Uppsala University, Uppsala, Sweden., Tayo BO; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois, USA., Thorleifsson G; deCODE Genetics, Amgen, Inc., Reykjavik, Iceland., Tyrer JP; Department of Oncology, University of Cambridge, Cambridge, UK., van Dijk S; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., van Schoor NM; Department of Epidemiology and Biostatistics, Institute for Research in Extramural Medicine (EMGO) Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands., van der Velde N; 1] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [2] Section of Geriatrics, Department of Internal Medicine, Academic Medical Center, Amsterdam, the Netherlands., van Heemst D; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., van Oort FV; Department of Child and Adolescent Psychiatry, Psychology, Erasmus University Medical Center, Rotterdam, the Netherlands., Vermeulen SH; 1] Department for Health Evidence, Radboud University Medical Centre, Nijmegen, the Netherlands. [2] Department of Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands., Verweij N; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Vonk JM; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Waite LL; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Wennauer R; Department of Clinical Chemistry, Ulm University Medical Centre, Ulm, Germany., Wilkens LR; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Willenborg C; 1] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), partner site Hamburg-Lubeck-Kiel, Lubeck, Germany. [2] Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany., Wilsgaard T; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Tromsø, Tromsø, Norway., Wojczynski MK; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Wong A; MRC Unit for Lifelong Health and Ageing at University College London, London, UK., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Zhang Q; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Arveiler D; Department of Epidemiology and Public Health, University of Strasbourg, Faculty of Medicine, Strasbourg, France., Bakker SJ; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Beilby J; 1] PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia, Australia. [2] Pathology and Laboratory Medicine, University of Western Australia, Perth, Western Australia, Australia., Bergman RN; Cedars-Sinai Diabetes and Obesity Research Institute, Los Angeles, California, USA., Bergmann S; 1] Swiss Institute of Bioinformatics, Lausanne, Switzerland. [2] Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland., Biffar R; Department of Prosthetic Dentistry, Gerostomatology and Dental Materials, University Medicine Greifswald, Greifswald, Germany., Blangero J; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA., Boomsma DI; Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands., Bornstein SR; Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Bovet P; 1] Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne, Lausanne, Switzerland. [2] Ministry of Health, Victoria, Republic of Seychelles., Brambilla P; Laboratory Medicine, Hospital of Desio, Department of Health Sciences, University of Milano, Bicocca, Italy., Brown MJ; Clinical Pharmacology Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Campbell H; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Caulfield MJ; 1] Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. [2] Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Collins R; Clinical Trial Service Unit, Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Collins FS; Genome Technology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Crawford DC; 1] Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA. [2] Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Cupples LA; 1] National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, USA. [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Danesh J; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., den Ruijter HM; 1] Experimental Cardiology Laboratory, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands. [2] Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands., Erbel R; Clinic of Cardiology, West German Heart Centre, University Hospital Essen, Essen, Germany., Erdmann J; 1] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), partner site Hamburg-Lubeck-Kiel, Lubeck, Germany. [2] Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany., Eriksson JG; 1] National Institute for Health and Welfare, Helsinki, Finland. [2] Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland. [3] Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland., Farrall M; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK., Ferrannini E; 1] Department of Internal Medicine, University of Pisa, Pisa, Italy. [2] National Research Council (CNR) Institute of Clinical Physiology, University of Pisa, Pisa, Italy., Ferrières J; Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse, France., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK., Forouhi NG; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Kingston, Jamaica., Gansevoort RT; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Gejman PV; NorthShore University HealthSystem, University of Chicago, Evanston, Illinois, USA., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Golay A; Service of Therapeutic Education for Diabetes, Obesity and Chronic Diseases, Geneva University Hospital, Geneva, Switzerland., Gottesman O; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Gudnason V; 1] Icelandic Heart Association, Kopavogur, Iceland. [2] University of Iceland, Reykjavik, Iceland., Gyllensten U; Department of Immunology, Genetics and Pathology, SciLifeLab, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden., Haas DW; Department of Medicine, Pharmacology, Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Hall AS; Leeds MRC Medical Bioinformatics Centre, University of Leeds, Leeds, UK., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Hattersley AT; Institute of Biomedical and Clinical Science, University of Exeter, Exeter, UK., Heath AC; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Hengstenberg C; 1] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany. [2] Deutsches Herzzentrum München, Technische Universität München, Munich, Germany., Hicks AA; Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano, Italy (affiliated institute of the University of Lübeck, Lübeck, Germany)., Hindorff LA; Division of Genomic Medicine, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Hingorani AD; Institute of Cardiovascular Science, University College London, London, UK., Hofman A; 1] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [2] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands., Humphries SE; Centre for Cardiovascular Genetics, Institute of Cardiovascular Sciences, University College London, London, UK., Hunt SC; Cardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA., Hypponen E; 1] School of Population Health, University of South Australia, Adelaide, South Australia, Australia. [2] Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia. [3] South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. [4] Centre for Paediatric Epidemiology and Biostatistics, University College London Institute of Child Health, London, UK., Jacobs KB; 1] Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA. [2] Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA., Jarvelin MR; 1] Department of Epidemiology and Biostatistics, Imperial College London, London, UK. [2] National Institute for Health and Welfare, Oulu, Finland. [3] MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK. [4] Unit of Primary Care, Oulu University Hospital, Oulu, Finland. [5] Biocenter Oulu, University of Oulu, Oulu, Finland. [6] Institute of Health Sciences, University of Oulu, Oulu, Finland., Jousilahti P; National Institute for Health and Welfare, Helsinki, Finland., Jula AM; National Institute for Health and Welfare, Helsinki, Finland., Kaprio J; 1] National Institute for Health and Welfare, Helsinki, Finland. [2] Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland. [3] Hjelt Institute Department of Public Health, University of Helsinki, Helsinki, Finland., Kastelein JJ; Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands., Kayser M; 1] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [2] Department of Forensic Molecular Biology, Erasmus Medical Center, Rotterdam, the Netherlands., Kee F; UK Clinical Research Collaboration Centre of Excellence for Public Health (Northern Ireland), Queens University of Belfast, Belfast, UK., Keinanen-Kiukaanniemi SM; 1] Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland. [2] Unit of General Practice, Oulu University Hospital, Oulu, Finland., Kiemeney LA; 1] Department for Health Evidence, Radboud University Medical Centre, Nijmegen, the Netherlands. [2] Department of Urology, Radboud University Medical Centre, Nijmegen, the Netherlands., Kooner JS; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Imperial College Healthcare NHS Trust, London, UK. [3] National Heart and Lung Institute, Imperial College London, London, UK., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Koskinen S; National Institute for Health and Welfare, Helsinki, Finland., Kovacs P; 1] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany. [2] Department of Medicine, University of Leipzig, Leipzig, Germany., Kraja AT; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Kumari M; Department of Epidemiology and Public Health, University College London, London, UK., Kuusisto J; Department of Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Lakka TA; 1] Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. [2] Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland. [3] Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Langenberg C; 1] Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. [2] Department of Epidemiology and Public Health, University College London, London, UK., Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland., Lupoli S; 1] Department of Health Sciences, University of Milano, Milan, Italy. [2] Fondazione Filarete, Milan, Italy., Madden PA; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Männistö S; National Institute for Health and Welfare, Helsinki, Finland., Manunta P; 1] Division of Nephrology and Dialysis, San Raffaele Scientific Institute, Milan, Italy. [2] Università Vita-Salute San Raffaele, Milan, Italy., Marette A; 1] Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada. [2] Institute of Nutrition and Functional Foods, Laval University, Quebec City, Quebec, Canada., Matise TC; Department of Genetics, Rutgers University, Piscataway, New Jersey, USA., McKnight B; Department of Biostatistics, University of Washington, Seattle, Washington, USA., Meitinger T; DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany., Moll FL; Department of Surgery, University Medical Center Utrecht, Utrecht, the Netherlands., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Morris AD; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Morris AP; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [3] Department of Biostatistics, University of Liverpool, Liverpool, UK., Murray JC; Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA., Nelis M; Estonian Genome Center, University of Tartu, Tartu, Estonia., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ong KK; 1] Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. [2] MRC Unit for Lifelong Health and Ageing at University College London, London, UK., Ouwehand WH; 1] Department of Haematology, University of Cambridge, Cambridge, UK. [2] NHS Blood and Transplant, Cambridge, UK., Pasterkamp G; Experimental Cardiology Laboratory, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Peters A; 1] Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany. [3] Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Pramstaller PP; 1] Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano, Italy (affiliated institute of the University of Lübeck, Lübeck, Germany). [2] Department of Neurology, General Central Hospital, Bolzano, Italy., Price JF; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Qi L; 1] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA., Raitakari OT; 1] Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland. [2] Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Rao DC; 1] Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA. [3] Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Rice TK; 1] Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Ritchie M; Center for Systems Genomics, Pennsylvania State University, University Park, Pennsylvania, USA., Rudan I; 1] Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK. [2] Croatian Centre for Global Health, Faculty of Medicine, University of Split, Split, Croatia., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Samani NJ; 1] Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK. [2] National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Saramies J; South Carelia Central Hospital, Lappeenranta, Finland., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Schwarz PE; 1] Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. [2] Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), Dresden, Germany., Sebert S; Institute of Health Sciences, University of Oulu, Oulu, Finland., Sever P; International Centre for Circulatory Health, Imperial College London, London, UK., Shuldiner AR; 1] Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA. [2] Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA. [3] Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland, USA., Sinisalo J; Helsinki University Central Hospital Heart and Lung Center, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland., Steinthorsdottir V; deCODE Genetics, Amgen, Inc., Reykjavik, Iceland., Stolk RP; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Tardif JC; 1] Montreal Heart Institute, Montreal, Quebec, Canada. [2] Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Tönjes A; 1] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany. [2] Department of Medicine, University of Leipzig, Leipzig, Germany., Tremblay A; Department of Kinesiology, Laval University, Quebec City, Quebec, Canada., Tremoli E; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano and Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy., Virtamo J; National Institute for Health and Welfare, Helsinki, Finland., Vohl MC; 1] Institute of Nutrition and Functional Foods, Laval University, Quebec City, Quebec, Canada. [2] Department of Food Science and Nutrition, Laval University, Quebec City, Quebec, Canada., Amouyel P; Institut Pasteur de Lille, INSERM U744, Université de Lille 2, Lille, France., Asselbergs FW; 1] Institute of Cardiovascular Science, University College London, London, UK. [2] Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands. [3] Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, the Netherlands., Assimes TL; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Bochud M; 1] Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne, Lausanne, Switzerland. [2] Ministry of Health, Victoria, Republic of Seychelles., Boehm BO; 1] Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, Ulm, Germany. [2] Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore., Boerwinkle E; Health Science Center at Houston, University of Texas, Houston, Texas, USA., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Cauchi S; 1] CNRS UMR 8199, Lille, France. [2] European Genomic Institute for Diabetes, Lille, France. [3] Université de Lille 2, Lille, France., Chambers JC; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Department of Epidemiology and Biostatistics, Imperial College London, London, UK. [3] Imperial College Healthcare NHS Trust, London, UK., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Cooper RS; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois, USA., de Bakker PI; 1] Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands. [2] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. [3] Department of Epidemiology, University Medical Center Utrecht, Utrecht, the Netherlands., Dedoussis G; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, USA., Franks PW; 1] Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA. [2] Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hospital, Malmö, Sweden. [3] Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden., Froguel P; 1] Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK. [2] CNRS UMR 8199, Lille, France. [3] European Genomic Institute for Diabetes, Lille, France. [4] Université de Lille 2, Lille, France., Groop LC; 1] Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland. [2] Lund University Diabetes Centre, Lund University, Malmö, Sweden. [3] Diabetes and Endocrinology Unit, Department of Clinical Science, Lund University, Malmö, Sweden., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Hamsten A; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Hayes MG; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Hui J; 1] PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia, Australia. [2] Pathology and Laboratory Medicine, University of Western Australia, Perth, Western Australia, Australia. [3] School of Population Health, University of South Australia, Adelaide, South Australia, Australia. [4] Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia., Hunter DJ; 1] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA. [3] Department of Epidemiology, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA., Hveem K; Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway., Jukema JW; 1] Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. [2] Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, the Netherlands. [3] Interuniversity Cardiology Institute of the Netherlands (ICIN), Utrecht, the Netherlands., Kaplan RC; Department of Epidemiology and Population Health, Albert Einstein College of Medicine. Belfer, New York, USA., Kivimaki M; Department of Epidemiology and Public Health, University College London, London, UK., Kuh D; MRC Unit for Lifelong Health and Ageing at University College London, London, UK., Laakso M; Department of Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Liu Y; Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., März W; 1] Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany. [2] Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria. [3] Synlab Academy, Synlab Services, Mannheim, Germany., Melbye M; 1] Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark. [2] Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Moebus S; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany., Munroe PB; 1] Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. [2] Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Njølstad I; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Tromsø, Tromsø, Norway., Oostra BA; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands. [2] Center for Medical Systems Biology, Leiden, the Netherlands. [3] Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., Palmer CN; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Perola M; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] National Institute for Health and Welfare, Helsinki, Finland. [3] Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland., Pérusse L; 1] Institute of Nutrition and Functional Foods, Laval University, Quebec City, Quebec, Canada. [2] Department of Kinesiology, Laval University, Quebec City, Quebec, Canada., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Powell JE; 1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. [2] University of Queensland Diamantina Institute, Translation Research Institute, Brisbane, Queensland, Australia., Power C; Centre for Paediatric Epidemiology and Biostatistics, University College London Institute of Child Health, London, UK., Quertermous T; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Rauramaa R; 1] Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. [2] Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Reinmaa E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Ridker PM; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA. [2] Harvard Medical School, Boston, Massachusetts, USA., Rivadeneira F; 1] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [2] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [3] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-University of California, Los Angeles Medical Center, Torrance, California, USA., Saaristo TE; 1] Finnish Diabetes Association, Tampere, Finland. [2] Pirkanmaa Hospital District, Tampere, Finland., Saleheen D; 1] Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [2] Center for Non-Communicable Diseases, Karatchi, Pakistan. [3] Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Schlessinger D; Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA., Slagboom PE; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Snieder H; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Strauch K; 1] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Chair of Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians Universität, Neuherberg, Germany., Stumvoll M; 1] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany. [2] Department of Medicine, University of Leipzig, Leipzig, Germany., Tuomilehto J; 1] National Institute for Health and Welfare, Helsinki, Finland. [2] Instituto de Investigacion Sanitaria del Hospital Universario La Paz (IdiPAZ), Madrid, Spain. [3] Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia. [4] Centre for Vascular Prevention, Danube University Krems, Krems, Austria., Uusitupa M; 1] Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland. [2] Research Unit, Kuopio University Hospital, Kuopio, Finland., van der Harst P; 1] Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. [2] Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. [3] Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, the Netherlands., Völzke H; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Walker M; Institute of Cellular Medicine, Newcastle University, Newcastle, UK., Wareham NJ; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Watkins H; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK., Wichmann HE; 1] Chair of Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians Universität, Munich, Germany. [2] Klinikum Großhadern, Munich, Germany. [3] Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Wilson JF; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Zanen P; Department of Pulmonology, University Medical Center Utrecht, Utrecht, the Netherlands., Deloukas P; 1] Wellcome Trust Sanger Institute, Hinxton, UK. [2] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. [3] King Abdulaziz University, Jeddah, Saudi Arabia., Heid IM; 1] Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany. [2] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Lindgren CM; 1] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Speliotes EK; 1] Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Thorsteinsdottir U; 1] deCODE Genetics, Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Barroso I; 1] Wellcome Trust Sanger Institute, Hinxton, UK. [2] University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. [3] NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Fox CS; National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, USA., North KE; 1] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [2] Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Strachan DP; Division of Population Health Sciences and Education, St George's, University of London, London, UK., Beckmann JS; 1] Swiss Institute of Bioinformatics, Lausanne, Switzerland. [2] Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland. [3] Service of Medical Genetics, CHUV University Hospital, Lausanne, Switzerland., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Borecki IB; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., McCarthy MI; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. [3] Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Trust, Oxford, UK., Metspalu A; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Stefansson K; 1] deCODE Genetics, Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Uitterlinden AG; 1] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [2] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [3] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., van Duijn CM; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands. [2] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [3] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands. [4] Center for Medical Systems Biology, Leiden, the Netherlands., Franke L; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Willer CJ; 1] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Price AL; 1] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [2] Department of Epidemiology, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA. [3] Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA., Lettre G; 1] Montreal Heart Institute, Montreal, Quebec, Canada. [2] Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Loos RJ; 1] Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. [2] Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [3] Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [4] Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Weedon MN; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Ingelsson E; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden. [3] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., O'Connell JR; 1] Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA. [2] Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Chasman DI; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA. [2] Harvard Medical School, Boston, Massachusetts, USA., Goddard ME; 1] Biosciences Research Division, Department of Primary Industries, Melbourne, Victoria, Australia. [2] Department of Food and Agricultural Systems, University of Melbourne, Melbourne, Victoria, Australia., Visscher PM; 1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. [2] University of Queensland Diamantina Institute, Translation Research Institute, Brisbane, Queensland, Australia., Hirschhorn JN; 1] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [3] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.
Publikováno v:
Nature genetics [Nat Genet] 2014 Nov; Vol. 46 (11), pp. 1173-86. Date of Electronic Publication: 2014 Oct 05.
Autor:
Berndt SI; US Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR, Workalemahu T, Hu YJ, Lee SH, Liang L, Lin DY, Min JL, Neale BM, Thorleifsson G, Yang J, Albrecht E, Amin N, Bragg-Gresham JL, Cadby G, den Heijer M, Eklund N, Fischer K, Goel A, Hottenga JJ, Huffman JE, Jarick I, Johansson Å, Johnson T, Kanoni S, Kleber ME, König IR, Kristiansson K, Kutalik Z, Lamina C, Lecoeur C, Li G, Mangino M, McArdle WL, Medina-Gomez C, Müller-Nurasyid M, Ngwa JS, Nolte IM, Paternoster L, Pechlivanis S, Perola M, Peters MJ, Preuss M, Rose LM, Shi J, Shungin D, Smith AV, Strawbridge RJ, Surakka I, Teumer A, Trip MD, Tyrer J, Van Vliet-Ostaptchouk JV, Vandenput L, Waite LL, Zhao JH, Absher D, Asselbergs FW, Atalay M, Attwood AP, Balmforth AJ, Basart H, Beilby J, Bonnycastle LL, Brambilla P, Bruinenberg M, Campbell H, Chasman DI, Chines PS, Collins FS, Connell JM, Cookson WO, de Faire U, de Vegt F, Dei M, Dimitriou M, Edkins S, Estrada K, Evans DM, Farrall M, Ferrario MM, Ferrières J, Franke L, Frau F, Gejman PV, Grallert H, Grönberg H, Gudnason V, Hall AS, Hall P, Hartikainen AL, Hayward C, Heard-Costa NL, Heath AC, Hebebrand J, Homuth G, Hu FB, Hunt SE, Hyppönen E, Iribarren C, Jacobs KB, Jansson JO, Jula A, Kähönen M, Kathiresan S, Kee F, Khaw KT, Kivimäki M, Koenig W, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Laitinen JH, Lakka TA, Langenberg C, Launer LJ, Lind L, Lindström J, Liu J, Liuzzi A, Lokki ML, Lorentzon M, Madden PA, Magnusson PK, Manunta P, Marek D, März W, Mateo Leach I, McKnight B, Medland SE, Mihailov E, Milani L, Montgomery GW, Mooser V, Mühleisen TW, Munroe PB, Musk AW, Narisu N, Navis G, Nicholson G, Nohr EA, Ong KK, Oostra BA, Palmer CN, Palotie A, Peden JF, Pedersen N, Peters A, Polasek O, Pouta A, Pramstaller PP, Prokopenko I, Pütter C, Radhakrishnan A, Raitakari O, Rendon A, Rivadeneira F, Rudan I, Saaristo TE, Sambrook JG, Sanders AR, Sanna S, Saramies J, Schipf S, Schreiber S, Schunkert H, Shin SY, Signorini S, Sinisalo J, Skrobek B, Soranzo N, Stančáková A, Stark K, Stephens JC, Stirrups K, Stolk RP, Stumvoll M, Swift AJ, Theodoraki EV, Thorand B, Tregouet DA, Tremoli E, Van der Klauw MM, van Meurs JB, Vermeulen SH, Viikari J, Virtamo J, Vitart V, Waeber G, Wang Z, Widén E, Wild SH, Willemsen G, Winkelmann BR, Witteman JC, Wolffenbuttel BH, Wong A, Wright AF, Zillikens MC, Amouyel P, Boehm BO, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Cupples LA, Cusi D, Dedoussis GV, Erdmann J, Eriksson JG, Franks PW, Froguel P, Gieger C, Gyllensten U, Hamsten A, Harris TB, Hengstenberg C, Hicks AA, Hingorani A, Hinney A, Hofman A, Hovingh KG, Hveem K, Illig T, Jarvelin MR, Jöckel KH, Keinanen-Kiukaanniemi SM, Kiemeney LA, Kuh D, Laakso M, Lehtimäki T, Levinson DF, Martin NG, Metspalu A, Morris AD, Nieminen MS, Njølstad I, Ohlsson C, Oldehinkel AJ, Ouwehand WH, Palmer LJ, Penninx B, Power C, Province MA, Psaty BM, Qi L, Rauramaa R, Ridker PM, Ripatti S, Salomaa V, Samani NJ, Snieder H, Sørensen TI, Spector TD, Stefansson K, Tönjes A, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Vollenweider P, Wallaschofski H, Wareham NJ, Watkins H, Wichmann HE, Wilson JF, Abecasis GR, Assimes TL, Barroso I, Boehnke M, Borecki IB, Deloukas P, Fox CS, Frayling T, Groop LC, Haritunian T, Heid IM, Hunter D, Kaplan RC, Karpe F, Moffatt MF, Mohlke KL, O'Connell JR, Pawitan Y, Schadt EE, Schlessinger D, Steinthorsdottir V, Strachan DP, Thorsteinsdottir U, van Duijn CM, Visscher PM, Di Blasio AM, Hirschhorn JN, Lindgren CM, Morris AP, Meyre D, Scherag A, McCarthy MI, Speliotes EK, North KE, Loos RJ, Ingelsson E
Publikováno v:
Nature genetics [Nat Genet] 2013 May; Vol. 45 (5), pp. 501-12. Date of Electronic Publication: 2013 Apr 07.
Autor:
Cvejic A; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, United Kingdom., Haer-Wigman L; Department of Experimental Immunohaematology, Sanquin Research, 1066 CX, Amsterdam, The Netherlands.; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, 1066 CX, The Netherlands., Stephens JC; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., Kostadima M; EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom., Smethurst PA; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., Frontini M; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., van den Akker E; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, 1066 CX, The Netherlands.; Department of Hematopoiesis, Sanquin Research, Amsterdam, 1066 CX, The Netherlands., Bertone P; EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom., Bielczyk-Maczyńska E; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., Farrow S; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., Fehrmann RS; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, 9700 RB, The Netherlands., Gray A; NHS Blood and Transplant, Tooting, London, SW17 0RB, United Kingdom., de Haas M; Department of Experimental Immunohaematology, Sanquin Research, 1066 CX, Amsterdam, The Netherlands.; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, 1066 CX, The Netherlands., Haver VG; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands., Jordan G; Somerville, Massachusetts, USA., Karjalainen J; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, 9700 RB, The Netherlands., Kerstens HH; Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, 6525 GA, The Netherlands., Kiddle G; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., Lloyd-Jones H; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., Needs M; NHS Blood and Transplant, Tooting, London, SW17 0RB, United Kingdom., Poole J; International Blood Group Reference Laboratory, NHS Blood and Transplant, North Bristol Park, Northway, Filton, Bristol, BS34 7QH, United Kingdom., Soussan AA; Department of Experimental Immunohaematology, Sanquin Research, 1066 CX, Amsterdam, The Netherlands.; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, 1066 CX, The Netherlands., Rendon A; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom.; MRC Biostatistics Unit, Institute of Public Health, Cambridge, CB2 0SR, United Kingdom., Rieneck K; Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen, DK-2100, Denmark., Sambrook JG; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., Schepers H; University of Groningen, University Medical Center Groningen, Department of Experimental Hematology, Groningen, 9700 RB, The Netherlands.; University of Groningen, University Medical Center Groningen, Department of Stem Cell Biology, Groningen, 9700 RB, The Netherlands., Silljé HHW; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands., Sipos B; EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom., Swinkels D; Department of Laboratory Medicine, Laboratory of Genetic, Endocrine and Metabolic diseases, Radboud University Medical Centre, Nijmegen, 6500 HB, The Netherlands., Tamuri AU; EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands., Watkins NA; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., Westra HJ; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, 9700 RB, The Netherlands., Stemple D; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, United Kingdom., Franke L; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, 9700 RB, The Netherlands., Soranzo N; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, United Kingdom., Stunnenberg HG; Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, 6525 GA, The Netherlands., Goldman N; EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, 9700 RB, The Netherlands.; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands., van der Schoot CE; Department of Experimental Immunohaematology, Sanquin Research, 1066 CX, Amsterdam, The Netherlands.; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, 1066 CX, The Netherlands., Ouwehand WH; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom., Albers CA; Department of Haematology, University of Cambridge, CB2 0PT, United Kingdom.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, United Kingdom.; NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, United Kingdom.; NHS Blood and Transplant, Cambridge, CB2 0PT, United Kingdom.; Department of Human Genetics, Radboud University Medical Centre, Nijmegen, 6500 HB, The Netherlands.
Publikováno v:
Nature genetics [Nat Genet] 2013 May; Vol. 45 (5), pp. 542-545. Date of Electronic Publication: 2013 Apr 07.
Autor:
Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, Ingelsson E, Saleheen D, Erdmann J, Goldstein BA, Stirrups K, König IR, Cazier JB, Johansson A, Hall AS, Lee JY, Willer CJ, Chambers JC, Esko T, Folkersen L, Goel A, Grundberg E, Havulinna AS, Ho WK, Hopewell JC, Eriksson N, Kleber ME, Kristiansson K, Lundmark P, Lyytikäinen LP, Rafelt S, Shungin D, Strawbridge RJ, Thorleifsson G, Tikkanen E, Van Zuydam N, Voight BF, Waite LL, Zhang W, Ziegler A, Absher D, Altshuler D, Balmforth AJ, Barroso I, Braund PS, Burgdorf C, Claudi-Boehm S, Cox D, Dimitriou M, Do R, Doney AS, El Mokhtari N, Eriksson P, Fischer K, Fontanillas P, Franco-Cereceda A, Gigante B, Groop L, Gustafsson S, Hager J, Hallmans G, Han BG, Hunt SE, Kang HM, Illig T, Kessler T, Knowles JW, Kolovou G, Kuusisto J, Langenberg C, Langford C, Leander K, Lokki ML, Lundmark A, McCarthy MI, Meisinger C, Melander O, Mihailov E, Maouche S, Morris AD, Müller-Nurasyid M, Nikus K, Peden JF, Rayner NW, Rasheed A, Rosinger S, Rubin D, Rumpf MP, Schäfer A, Sivananthan M, Song C, Stewart AF, Tan ST, Thorgeirsson G, van der Schoot CE, Wagner PJ, Wells GA, Wild PS, Yang TP, Amouyel P, Arveiler D, Basart H, Boehnke M, Boerwinkle E, Brambilla P, Cambien F, Cupples AL, de Faire U, Dehghan A, Diemert P, Epstein SE, Evans A, Ferrario MM, Ferrières J, Gauguier D, Go AS, Goodall AH, Gudnason V, Hazen SL, Holm H, Iribarren C, Jang Y, Kähönen M, Kee F, Kim HS, Klopp N, Koenig W, Kratzer W, Kuulasmaa K, Laakso M, Laaksonen R, Lee JY, Lind L, Ouwehand WH, Parish S, Park JE, Pedersen NL, Peters A, Quertermous T, Rader DJ, Salomaa V, Schadt E, Shah SH, Sinisalo J, Stark K, Stefansson K, Trégouët DA, Virtamo J, Wallentin L, Wareham N, Zimmermann ME, Nieminen MS, Hengstenberg C, Sandhu MS, Pastinen T, Syvänen AC, Hovingh GK, Dedoussis G, Franks PW, Lehtimäki T, Metspalu A, Zalloua PA, Siegbahn A, Schreiber S, Ripatti S, Blankenberg SS, Perola M, Clarke R, Boehm BO, O'Donnell C, Reilly MP, März W, Collins R, Kathiresan S, Hamsten A, Kooner JS, Thorsteinsdottir U, Danesh J, Palmer CN, Roberts R, Watkins H, Schunkert H, Samani NJ
Publikováno v:
Nature genetics [Nat Genet] 2013 Jan; Vol. 45 (1), pp. 25-33. Date of Electronic Publication: 2012 Dec 02.