Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eriksson, Nicholas"'
Autor:
Demontis D; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.; Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark., Walters RK; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Martin J; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; MRC Centre for Neuropsychiatric Genetics & Genomics, School of Medicine, Cardiff University, Cardiff, UK., Mattheisen M; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.; Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.; Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany., Als TD; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.; Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark., Agerbo E; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.; Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark., Baldursson G; Department of Child and Adolescent Psychiatry, National University Hospital, Reykjavik, Iceland., Belliveau R; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bybjerg-Grauholm J; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Bækvad-Hansen M; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Cerrato F; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chambert K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Churchhouse C; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Dumont A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Eriksson N; 23andMe, Inc, Mountain View, CA, USA., Gandal M; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Center for Autism Research and Treatment and Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA., Goldstein JI; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Grasby KL; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Grove J; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.; Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Gudmundsson OO; Department of Child and Adolescent Psychiatry, National University Hospital, Reykjavik, Iceland.; deCODE genetics/Amgen, Reykjavík, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Hansen CS; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.; Institute of Biological Psychiatry, MHC Sct. Hans, Mental Health Services Copenhagen, Roskilde, Denmark., Hauberg ME; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.; Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark., Hollegaard MV; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Howrigan DP; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Huang H; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Maller JB; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Genomics plc, Oxford, UK., Martin AR; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Moran J; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pallesen J; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.; Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark., Palmer DS; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pedersen CB; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.; Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark., Pedersen MG; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.; Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark., Poterba T; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Poulsen JB; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Ripke S; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Robinson EB; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Department of Epidemiology, Harvard Chan School of Public Health, Boston, MA, USA., Satterstrom FK; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Stefansson H; deCODE genetics/Amgen, Reykjavík, Iceland., Stevens C; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Turley P; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Walters GB; deCODE genetics/Amgen, Reykjavík, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Won H; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Center for Autism Research and Treatment and Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA., Wright MJ; Queensland Brain Institute, University of Queensland, Brisbane, Australia., Andreassen OA; NORMENT KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Asherson P; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Burton CL; Psychiatry, Neurosciences and Mental Health, The Hospital for Sick Children, University of Toronto, Toronto, Canada., Boomsma DI; Department of Biological Psychology, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.; EMGO Institute for Health and Care Research, Amsterdam, The Netherlands., Cormand B; Departament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Barcelona, Catalonia, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Madrid, Spain.; Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Catalonia, Spain.; Institut de Recerca Sant Joan de Déu (IRSJD), Esplugues de Llobregat, Barcelona, Catalonia, Spain., Dalsgaard S; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark., Franke B; Departments of Human Genetics (855) and Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands., Gelernter J; Department of Psychiatry, Genetics, and Neuroscience, Yale University School of Medicine, New Haven, CT, USA.; Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA., Geschwind D; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Center for Autism Research and Treatment and Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Hakonarson H; The Center for Applied Genomics, The Children´s Hospital of Philadelphia, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Haavik J; K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, Bergen, Norway.; Haukeland University Hospital, Bergen, Norway., Kranzler HR; Department of Psychiatry, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Veterans Integrated Service Network (VISN4) Mental Illness Research, Education, and Clinical Center (MIRECC), Crescenz VA Medical Center, Philadephia, PA, USA., Kuntsi J; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Langley K; MRC Centre for Neuropsychiatric Genetics & Genomics, School of Medicine, Cardiff University, Cardiff, UK.; School of Psychology, Cardiff University, Cardiff, UK., Lesch KP; Division of Molecular Psychiatry, Center of Mental Health, University of Wuerzburg, Wuerzburg, Germany.; Department of Neuroscience, School for Mental Health and Neuroscience (MHENS), Maastricht University, Maastricht, The Netherlands.; Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University, Moscow, Russia., Middeldorp C; Department of Biological Psychology, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.; Child Health Research Centre, University of Queensland, Brisbane, Australia.; Child and Youth Mental Health Service, Children's Health Queensland Hospital and Health Service, Brisbane, Australia., Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany., Rohde LA; Department of Psychiatry, Faculty of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; ADHD Outpatient Clinic, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil., Roussos P; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Friedman Brain Institute, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mental Illness Research Education and Clinical Center (MIRECC), James J. Peters VA Medical Center, Bronx, New York, USA., Schachar R; Psychiatry, Neurosciences and Mental Health, The Hospital for Sick Children, University of Toronto, Toronto, Canada., Sklar P; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Friedman Brain Institute, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sonuga-Barke EJS; Institute of Psychiatry, Psychology & Neuroscience, Kings College, London, UK., Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Departments of Genetics and Psychiatry, University of North Carolina, Chapel Hill, NC, USA., Thapar A; MRC Centre for Neuropsychiatric Genetics & Genomics, School of Medicine, Cardiff University, Cardiff, UK., Tung JY; 23andMe, Inc, Mountain View, CA, USA., Waldman ID; Department of Psychology, Emory University, Atlanta, GA, USA., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Stefansson K; deCODE genetics/Amgen, Reykjavík, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Nordentoft M; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Mental Health Services in the Capital Region of Denmark, Mental Health Center Copenhagen, University of Copenhagen, Copenhagen, Denmark., Hougaard DM; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Werge T; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Institute of Biological Psychiatry, MHC Sct. Hans, Mental Health Services Copenhagen, Roskilde, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Mors O; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Psychosis Research Unit, Aarhus University Hospital, Risskov, Denmark., Mortensen PB; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.; Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark., Daly MJ; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland., Faraone SV; Departments of Psychiatry and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA. sfaraone@childpsychresearch.org., Børglum AD; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark. anders@biomed.au.dk.; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark. anders@biomed.au.dk.; Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark. anders@biomed.au.dk., Neale BM; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. bneale@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. bneale@broadinstitute.org.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. bneale@broadinstitute.org.
Publikováno v:
Nature genetics [Nat Genet] 2019 Jan; Vol. 51 (1), pp. 63-75. Date of Electronic Publication: 2018 Nov 26.
Autor:
Tedja MS; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Wojciechowski R; Department of Epidemiology and Medicine, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA., Hysi PG; Section of Academic Ophthalmology, School of Life Course Sciences, King's College London, London, UK., Eriksson N; 23andMe, Inc., Mountain View, CA, USA., Furlotte NA; 23andMe, Inc., Mountain View, CA, USA., Verhoeven VJM; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands., Iglesias AI; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands., Meester-Smoor MA; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Tompson SW; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA., Fan Q; Centre for Quantitative Medicine, DUKE-National University of Singapore, Singapore, Singapore., Khawaja AP; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK., Cheng CY; Centre for Quantitative Medicine, DUKE-National University of Singapore, Singapore, Singapore.; Ocular Epidemiology Research Group, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Höhn R; Department of Ophthalmology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland.; Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Yamashiro K; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan., Wenocur A; Department of Ophthalmology, University of Pennsylvania, Philadelphia, PA, USA., Grazal C; Department of Ophthalmology, University of Pennsylvania, Philadelphia, PA, USA., Haller T; Estonian Genome Center, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Wedenoja J; Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Mannheim, Germany.; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wang YX; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Xie J; Centre for Eye Research Australia, Ophthalmology, Department of Surgery, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia., Mitchell P; Department of Ophthalmology, Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., Foster PJ; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK., Klein BEK; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA., Klein R; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA., Paterson AD; Program in Genetics and Genome Biology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada., Hosseini SM; Program in Genetics and Genome Biology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada., Shah RL; School of Optometry & Vision Sciences, Cardiff University, Cardiff, UK., Williams C; Department of Population Health Sciences, Bristol Medical School, Bristol, UK., Teo YY; Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University Health Systems, National University of Singapore, Singapore, Singapore., Tham YC; Ocular Epidemiology Research Group, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Gupta P; Department of Health Service Research, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Zhao W; Centre for Quantitative Medicine, DUKE-National University of Singapore, Singapore, Singapore.; Statistics Support Platform, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Shi Y; Statistics Support Platform, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Saw WY; Life Sciences Institute, National University of Singapore, Singapore, Singapore., Tai ES; Saw Swee Hock School of Public Health, National University Health Systems, National University of Singapore, Singapore, Singapore., Sim XL; Saw Swee Hock School of Public Health, National University Health Systems, National University of Singapore, Singapore, Singapore., Huffman JE; MRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Polašek O; Faculty of Medicine, University of Split, Split, Croatia., Hayward C; MRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Bencic G; Department of Ophthalmology, Sisters of Mercy University Hospital, Zagreb, Croatia., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Wilson JF; MRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Joshi PK; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan., Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Whisenhunt KN; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA., Zeller T; Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany., van der Spek PJ; Department of Bioinformatics, Erasmus Medical Center, Rotterdam, The Netherlands., Haak R; Department of Bioinformatics, Erasmus Medical Center, Rotterdam, The Netherlands., Meijers-Heijboer H; Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands.; Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands., van Leeuwen EM; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Iyengar SK; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.; Department of Ophthalmology and Visual Sciences, Case Western Reserve University and University Hospitals Eye Institute, Cleveland, OH, USA.; Department of Genetics, Case Western Reserve University, Cleveland, OH, USA., Lass JH; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.; Department of Ophthalmology and Visual Sciences, Case Western Reserve University and University Hospitals Eye Institute, Cleveland, OH, USA., Hofman A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague, The Netherlands., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Vingerling JR; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands., Lehtimäki T; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, Tampere, Finland., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Biino G; Institute of Molecular Genetics, National Research Council of Italy, Pavia, Italy., Concas MP; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, Italy., Schwantes-An TH; Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Department of Medical and Molecular Genetics, Indiana University, School of Medicine, Indianapolis, IN, USA., Igo RP Jr; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Cuellar-Partida G; Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Martin NG; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Craig JE; Department of Ophthalmology, Flinders University, Adelaide, South Australia, Australia., Gharahkhani P; Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Williams KM; Section of Academic Ophthalmology, School of Life Course Sciences, King's College London, London, UK., Nag A; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Rahi JS; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.; Great Ormond Street Institute of Child Health, University College London, London, UK.; Ulverscroft Vision Research Group, University College London, London, UK., Cumberland PM; Great Ormond Street Institute of Child Health, University College London, London, UK., Delcourt C; Université de Bordeaux, Inserm, Bordeaux Population Health Research Center, team LEHA, UMR 1219, F-33000, Bordeaux, France., Bellenguez C; Institut Pasteur de Lille, Lille, France.; Inserm, U1167, RID-AGE-Risk factors and molecular determinants of aging-related diseases, Lille, France.; Université de Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France., Ried JS; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Bergen AA; Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands.; Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands.; Netherlands Institute for Neurosciences (NIN-KNAW), Amsterdam, The Netherlands., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Wong TY; Academic Medicine Research Institute, Singapore, Singapore.; Retino Center, Singapore National Eye Centre, Singapore, Singapore., Hewitt AW; Centre for Eye Research Australia, Ophthalmology, Department of Surgery, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.; Department of Ophthalmology, Menzies Institute of Medical Research, University of Tasmania, Hobart, Tasmania, Australia.; Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia., Mackey DA; Centre for Eye Research Australia, Ophthalmology, Department of Surgery, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.; Department of Ophthalmology, Menzies Institute of Medical Research, University of Tasmania, Hobart, Tasmania, Australia.; Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia., Simpson CL; Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Department of Genetics, Genomics and Informatics, University of Tennessee Health Sciences Center, Memphis, TN, USA., Pfeiffer N; Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Pärssinen O; Department of Ophthalmology, Central Hospital of Central Finland, Jyväskylä, Finland.; Gerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland., Baird PN; Centre for Eye Research Australia, Ophthalmology, Department of Surgery, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia., Vitart V; MRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Amin N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., van Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Bailey-Wilson JE; Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Young TL; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA., Saw SM; Saw Swee Hock School of Public Health, National University Health Systems, National University of Singapore, Singapore, Singapore.; Myopia Research Group, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Stambolian D; Department of Ophthalmology, University of Pennsylvania, Philadelphia, PA, USA., MacGregor S; Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Guggenheim JA; School of Optometry & Vision Sciences, Cardiff University, Cardiff, UK., Tung JY; 23andMe, Inc., Mountain View, CA, USA., Hammond CJ; Section of Academic Ophthalmology, School of Life Course Sciences, King's College London, London, UK., Klaver CCW; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands. c.c.w.klaver@erasmusmc.nl.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands. c.c.w.klaver@erasmusmc.nl.; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands. c.c.w.klaver@erasmusmc.nl.
Publikováno v:
Nature genetics [Nat Genet] 2018 Jun; Vol. 50 (6), pp. 834-848. Date of Electronic Publication: 2018 May 28.
Autor:
Wray NR; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. naomi.wray@uq.edu.au.; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. naomi.wray@uq.edu.au., Ripke S; Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry and Psychotherapy, Universitätsmedizin Berlin Campus Charité Mitte, Berlin, Germany., Mattheisen M; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Trzaskowski M; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Byrne EM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Abdellaoui A; Department of Biological Psychology and EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Adams MJ; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Agerbo E; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark., Air TM; Discipline of Psychiatry, University of Adelaide, Adelaide, South Australia, Australia., Andlauer TMF; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Bacanu SA; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Bækvad-Hansen M; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Beekman AFT; Department of Psychiatry, Vrije Universiteit Medical Center and GGZ inGeest, Amsterdam, The Netherlands., Bigdeli TB; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA.; Virginia Institute for Psychiatric and Behavior Genetics, Richmond, VA, USA., Binder EB; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Blackwood DRH; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Bryois J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Buttenschøn HN; iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Department of Clinical Medicine, Translational Neuropsychiatry Unit, Aarhus University, Aarhus, Denmark., Bybjerg-Grauholm J; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Cai N; Statistical Genomics and Systems Genetics, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK.; Human Genetics, Wellcome Trust Sanger Institute, Cambridge, UK., Castelao E; Department of Psychiatry, University Hospital of Lausanne, Prilly, Switzerland., Christensen JH; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark., Clarke TK; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Coleman JIR; MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK., Colodro-Conde L; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Couvy-Duchesne B; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia., Craddock N; Psychological Medicine, Cardiff University, Cardiff, UK., Crawford GE; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.; Department of Pediatrics, Division of Medical Genetics, Duke University, Durham, NC, USA., Crowley CA; Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Dashti HS; Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Degenhardt F; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Life & Brain Center, Department of Genomics, University of Bonn, Bonn, Germany., Derks EM; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Direk N; Psychiatry, Dokuz Eylul University School of Medicine, Izmir, Turkey.; Epidemiology, Erasmus MC, Rotterdam, The Netherlands., Dolan CV; Department of Biological Psychology and EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Dunn EC; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Massachusetts General Hospital, Boston, MA, USA., Eley TC; MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK., Eriksson N; Research, 23andMe, Inc., Mountain View, CA, USA., Escott-Price V; Neuroscience and Mental Health, Cardiff University, Cardiff, UK., Kiadeh FHF; Bioinformatics, University of British Columbia, Vancouver, British Columbia, Canada., Finucane HK; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.; Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA, USA., Forstner AJ; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Life & Brain Center, Department of Genomics, University of Bonn, Bonn, Germany.; Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.; Human Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland., Frank J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Gaspar HA; MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK., Gill M; Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Giusti-Rodríguez P; Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Goes FS; Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA., Gordon SD; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Grove J; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Hall LS; Division of Psychiatry, University of Edinburgh, Edinburgh, UK.; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Hannon E; University of Exeter Medical School, Exeter, UK., Hansen CS; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Hansen TF; Danish Headache Centre, Department of Neurology, Rigshospitalet, Glostrup, Denmark.; Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Mental Health Services Capital Region of Denmark, Copenhagen, Denmark.; iPSYCH, Lundbeck Foundation Initiative for Psychiatric Research, Copenhagen, Denmark., Herms S; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Life & Brain Center, Department of Genomics, University of Bonn, Bonn, Germany.; Human Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland., Hickie IB; Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia., Hoffmann P; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Life & Brain Center, Department of Genomics, University of Bonn, Bonn, Germany.; Human Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine and Ernst Moritz Arndt University Greifswald, Greifswald, Germany., Horn C; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche, Ltd, Basel, Switzerland., Hottenga JJ; Department of Biological Psychology and EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Hougaard DM; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Hu M; Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA., Hyde CL; Statistics, Pfizer Global Research and Development, Groton, CT, USA., Ising M; Max Planck Institute of Psychiatry, Munich, Germany., Jansen R; Department of Psychiatry, Vrije Universiteit Medical Center and GGZ inGeest, Amsterdam, The Netherlands., Jin F; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA.; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA., Jorgenson E; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Knowles JA; Psychiatry and Behavioral Sciences, University of Southern California, Los Angeles, CA, USA., Kohane IS; Informatics Program, Boston Children's Hospital, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Kraft J; Department of Psychiatry and Psychotherapy, Universitätsmedizin Berlin Campus Charité Mitte, Berlin, Germany., Kretzschmar WW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Krogh J; Department of Endocrinology at Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine (IUMSP), University Hospital of Lausanne, Lausanne, Switzerland., Lane JM; Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA., Li Y; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Li Y; Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Lind PA; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Liu X; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA., Lu L; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA., MacIntyre DJ; Mental Health, NHS 24, Glasgow, UK.; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., MacKinnon DF; Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA., Maier RM; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Maier W; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany., Marchini J; Statistics, University of Oxford, Oxford, UK., Mbarek H; Department of Biological Psychology and EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., McGrath P; Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA., McGuffin P; MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK., Medland SE; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Mehta D; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; School of Psychology and Counseling, Queensland University of Technology, Brisbane, Queensland, Australia., Middeldorp CM; Department of Biological Psychology and EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Child and Youth Mental Health Service, Children's Health Queensland Hospital and Health Service, South Brisbane, Queensland, Australia.; Child Health Research Centre, University of Queensland, Brisbane, Queensland, Australia., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milaneschi Y; Department of Psychiatry, Vrije Universiteit Medical Center and GGZ inGeest, Amsterdam, The Netherlands., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mill J; University of Exeter Medical School, Exeter, UK., Mondimore FM; Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA., Montgomery GW; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Mostafavi S; Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; Statistics, University of British Columbia, Vancouver, British Columbia, Canada., Mullins N; MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK., Nauck M; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, University Medicine, University Medicine Greifswald, Greifswald, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Ng B; Statistics, University of British Columbia, Vancouver, British Columbia, Canada., Nivard MG; Department of Biological Psychology and EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Nyholt DR; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia., O'Reilly PF; MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK., Oskarsson H; Humus, Reykjavik, Iceland., Owen MJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Painter JN; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Pedersen CB; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark., Pedersen MG; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark., Peterson RE; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA.; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA., Pettersson E; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Peyrot WJ; Department of Psychiatry, Vrije Universiteit Medical Center and GGZ inGeest, Amsterdam, The Netherlands., Pistis G; Department of Psychiatry, University Hospital of Lausanne, Prilly, Switzerland., Posthuma D; Complex Trait Genetics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Clinical Genetics, Vrije Universiteit Medical Center, Amsterdam, The Netherlands., Purcell SM; Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA., Quiroz JA; Solid Biosciences, Boston, MA, USA., Qvist P; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark., Rice JP; Department of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Riley BP; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Rivera M; MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK.; Department of Biochemistry and Molecular Biology II, Institute of Neurosciences, Center for Biomedical Research, University of Granada, Granada, Spain., Saeed Mirza S; Epidemiology, Erasmus MC, Rotterdam, The Netherlands., Saxena R; Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA., Schoevers R; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Schulte EC; Department of Psychiatry and Psychotherapy, Medical Center of the University of Munich, Campus Innenstadt, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), Medical Center of the University of Munich, Campus Innenstadt, Munich, Germany., Shen L; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Shi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Shyn SI; Behavioral Health Services, Kaiser Permanente Washington, Seattle, WA, USA., Sigurdsson E; Faculty of Medicine, Department of Psychiatry, University of Iceland, Reykjavik, Iceland., Sinnamon GBC; School of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia., Smit JH; Department of Psychiatry, Vrije Universiteit Medical Center and GGZ inGeest, Amsterdam, The Netherlands., Smith DJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK., Stefansson H; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Steinberg S; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Stockmeier CA; Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS, USA., Streit F; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Strohmaier J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Tansey KE; College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK., Teismann H; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Thompson W; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Mental Health Services Capital Region of Denmark, Copenhagen, Denmark.; KG Jebsen Centre for Psychosis Research, Norway Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA., Thomson PA; Medical Genetics Section, CGEM, IGMM, University of Edinburgh, Edinburgh, UK., Thorgeirsson TE; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Tian C; Research, 23andMe, Inc., Mountain View, CA, USA., Traylor M; Clinical Neurosciences, University of Cambridge, Cambridge, UK., Treutlein J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Trubetskoy V; Department of Psychiatry and Psychotherapy, Universitätsmedizin Berlin Campus Charité Mitte, Berlin, Germany., Uitterlinden AG; Internal Medicine, Erasmus MC, Rotterdam, The Netherlands., Umbricht D; Roche Pharmaceutical Research and Early Development, Neuroscience, Ophthalmology and Rare Diseases Discovery and Translational Medicine Area, Roche Innovation Center Basel, F. Hoffmann-La Roche, Ltd, Basel, Switzerland., Van der Auwera S; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., van Hemert AM; Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands., Viktorin A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Visscher PM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Wang Y; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Mental Health Services Capital Region of Denmark, Copenhagen, Denmark.; KG Jebsen Centre for Psychosis Research, Norway Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Webb BT; Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA., Weinsheimer SM; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Mental Health Services Capital Region of Denmark, Copenhagen, Denmark., Wellmann J; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Willemsen G; Department of Biological Psychology and EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Wu Y; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Xi HS; Computational Sciences Center of Emphasis, Pfizer Global Research and Development, Cambridge, MA, USA., Yang J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Zhang F; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Arolt V; Department of Psychiatry, University of Münster, Munster, Germany., Baune BT; Discipline of Psychiatry, University of Adelaide, Adelaide, South Australia, Australia., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Boomsma DI; Department of Biological Psychology and EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Cichon S; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Human Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland.; Institute of Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany.; Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland., Dannlowski U; Department of Psychiatry, University of Münster, Munster, Germany., de Geus ECJ; Department of Biological Psychology and EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Institute, Vrije Universiteit Medical Center, Amsterdam, The Netherlands., DePaulo JR; Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA., Domenici E; Centre for Integrative Biology, Università degli Studi di Trento, Trento, Italy., Domschke K; Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Esko T; Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Hamilton SP; Psychiatry, Kaiser Permanente Northern California, San Francisco, CA, USA., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Heath AC; Department of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Hinds DA; Research, 23andMe, Inc., Mountain View, CA, USA., Kendler KS; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Kloiber S; Max Planck Institute of Psychiatry, Munich, Germany.; Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Lewis G; Division of Psychiatry, University College London, London, UK., Li QS; Neuroscience Therapeutic Area, Janssen Research and Development, LLC, Titusville, NJ, USA., Lucae S; Max Planck Institute of Psychiatry, Munich, Germany., Madden PFA; Department of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Martin NG; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., McIntosh AM; Division of Psychiatry, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Mors O; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Psychosis Research Unit, Aarhus University Hospital, Risskov, Aarhus, Denmark., Mortensen PB; iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark., Müller-Myhsok B; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Institute of Translational Medicine, University of Liverpool, Liverpool, UK., Nordentoft M; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Mental Health Center Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Life & Brain Center, Department of Genomics, University of Bonn, Bonn, Germany., O'Donovan MC; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Paciga SA; Human Genetics and Computational Biomedicine, Pfizer Global Research and Development, Groton, CT, USA., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Penninx BWJH; Department of Psychiatry, Vrije Universiteit Medical Center and GGZ inGeest, Amsterdam, The Netherlands., Perlis RH; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Psychiatry, Harvard Medical School, Boston, MA, USA., Porteous DJ; Medical Genetics Section, CGEM, IGMM, University of Edinburgh, Edinburgh, UK., Potash JB; Psychiatry, University of Iowa, Iowa City, IA, USA., Preisig M; Department of Psychiatry, University Hospital of Lausanne, Prilly, Switzerland., Rietschel M; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Schaefer C; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Schulze TG; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.; Institute of Psychiatric Phenomics and Genomics (IPPG), Medical Center of the University of Munich, Campus Innenstadt, Munich, Germany.; Human Genetics Branch, NIMH Division of Intramural Research Programs, Bethesda, MD, USA.; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany., Smoller JW; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Massachusetts General Hospital, Boston, MA, USA., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Tiemeier H; Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Child and Adolescent Psychiatry, Erasmus MC, Rotterdam, The Netherlands.; Psychiatry, Erasmus MC, Rotterdam, The Netherlands., Uher R; Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Weissman MM; Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.; Division of Epidemiology, New York State Psychiatric Institute, New York, NY, USA., Werge T; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Mental Health Services Capital Region of Denmark, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Winslow AR; Human Genetics and Computational Biomedicine, Pfizer Global Research and Development, Cambridge, MA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lewis CM; MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK.; Department of Medical and Molecular Genetics, King's College London, London, UK., Levinson DF; Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA., Breen G; MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK.; NIHR BRC for Mental Health, King's College London, London, UK., Børglum AD; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.; iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark., Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. pfsulliv@med.unc.edu.; Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. pfsulliv@med.unc.edu.; Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. pfsulliv@med.unc.edu.
Publikováno v:
Nature genetics [Nat Genet] 2018 May; Vol. 50 (5), pp. 668-681. Date of Electronic Publication: 2018 Apr 26.
Autor:
Barban N; Department of Sociology and Nuffield College, University of Oxford, Oxford, UK., Jansen R; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands., de Vlaming R; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran., Mandemakers JJ; Sociology of Consumption and Households, Wageningen University Research, Wageningen, the Netherlands., Tropf FC; Department of Sociology and Nuffield College, University of Oxford, Oxford, UK., Shen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Wilson JF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Chasman DI; Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Tragante V; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., van der Laan SW; Laboratory of Experimental Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Perry JR; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Kong A; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Ahluwalia TS; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark.; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Albrecht E; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Yerges-Armstrong L; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., Atzmon G; Department of Medicine, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, USA.; Department of Genetics, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, USA.; Department of Natural Science, University of Haifa, Haifa, Israel., Auro K; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland., Ayers K; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Bakshi A; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Ben-Avraham D; Department of Genetics, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, USA., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Bergman A; Departments of Systems and Computational Biology, of Pathology and of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA., Bertram L; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and of Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.; School of Public Health, Faculty of Medicine, Imperial College, London, UK., Bielak LF; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Bjornsdottir G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Bonder MJ; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Bui M; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Barbieri C; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milan, Italy., Cavadino A; Population, Policy and Practice, UCL Institute of Child Health, London, UK.; Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventative Medicine, Queen Mary University of London, London, UK., Chavarro JE; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Turman C; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Concas MP; Institute of Genetic and Biomedical Research, National Research Council, UOS of Sassari, Sassari, Italy., Cordell HJ; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Eibich P; Health Economics Research Centre, University of Oxford, Oxford, UK., Eriksson N; 23andMe, Inc., Mountain View, California, USA., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Eriksson J; Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Falahi F; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Felix JF; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Fontana MA; Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA., Franke L; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Gandin I; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Gaskins AJ; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Gunderson EP; Cardiovascular and Metabolic Conditions Section, Division of Research, Kaiser Permanente Northern California, Oakland, California, USA., Guo X; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA., Hayward C; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., He C; Department of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, Indiana, USA., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Huang H; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Kiechl S; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Kifley A; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney, Westmead, New South Wales, Australia., Kluttig A; Institute of Medical Epidemiology, Biostatistics and Informatics, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany., Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Lagou V; Department of Neurosciences, KU Leuven, Leuven, Belgium.; Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.; Translational Immunology Laboratory, VIB, Leuven, Belgium., Lecoeur C; University of Lille, CNRS, Institut Pasteur of Lille, Lille, France., Lahti J; Institute of Behavioral Sciences, University of Helsinki, Helsinki, Finland.; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland.; Folkhälsan Research Centre, Helsinki, Finland., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lind PA; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Herston Brisbane, Queensland, Australia., Liu T; Center for Lifespan Psychology, Max Planck Institute for Human Development and Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Mamasoula C; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Matteson L; Minnesota Center for Twin and Family Research, Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Mbarek H; Department of Biological Psychology, VU University, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., McArdle PF; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., McMahon G; School of Social and Community Medicine, University of Bristol, Bristol, UK., Meddens SF; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Complex Trait Genetics, VU University, Amsterdam, the Netherlands., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Miller M; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Missmer SA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Monnereau C; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Myhre R; Department of Genetics and Bioinformatics, Area of Health Data and Digitalization, Institute of Public Health, Oslo, Norway., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Nutile T; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy., Kalafati IP; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Porcu E; Istituto di Ricerca Genetica e Biomedica, CMR, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.; Dipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy., Prokopenko I; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, UK.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Rajan KB; Rush University Medical Center, Chicago, Illinois, USA., Rich-Edwards J; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Rietveld CA; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Rose LM; Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ryan KA; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., Saba Y; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, Austria., Schmidt D; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Stolk L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Streeten E; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., Tönjes A; Department of Medicine, University of Leipzig, Leipzig, Germany., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Ulivi S; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Wedenoja J; Department of Public Health, University of Helsinki, Helsinki, Finland., Wellmann J; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Willeit P; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.; King's British Heart Foundation Centre, King's College London, London, UK.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Yao J; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA., Yengo L; University of Lille, CNRS, Institut Pasteur of Lille, Lille, France.; Centre for Neurogenetics and Statistical Genomics, University of Queensland, Brisbane, Queensland, Australia., Zhao JH; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Zhao W; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Zhernakova DV; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Amin N; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Andrews H; Data Coordinating Center, New York State Psychiatric Institute, New York, New York, USA., Balkau B; University of Lille, CNRS, Institut Pasteur of Lille, Lille, France., Barzilai N; Department of Medicine, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, USA., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Biino G; Institute of Molecular Genetics, National Research Council of Italy, Pavia, Italy., Bisgaard H; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Bønnelykke K; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Boomsma DI; Department of Biological Psychology, VU University, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Buring JE; Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Cappellani S; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Ciullo M; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Cox SR; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Cucca F; Istituto di Ricerca Genetica e Biomedica, CMR, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.; Dipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milan, Italy., Davey-Smith G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., van Duijn CM; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., de Geus EJ; Department of Biological Psychology, VU University, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Eriksson JG; Folkhälsan Research Centre, Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.; Vasa Central Hospital, Vasa, Finland., Evans DA; Rush University Medical Center, Chicago, Illinois, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Sala CF; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milan, Italy., Froguel P; University of Lille, CNRS, Institut Pasteur of Lille, Lille, France., Gasparini P; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Division of Experimental Genetics, Sidra, Doha, Qatar., Girotto G; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Division of Experimental Genetics, Sidra, Doha, Qatar., Grabe HJ; Department of Psychiatry, University Medicine Greifswald, Greifswald, Germany., Greiser KH; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany., Groenen PJ; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands., de Haan HG; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Haerting J; Institute of Medical Epidemiology, Biostatistics and Informatics, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, USA., Heath AC; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Heikkilä K; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland., Hofman A; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Holliday EG; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia., Hopper J; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Hyppönen E; Population, Policy and Practice, UCL Institute of Child Health, London, UK.; Centre for Population Health Research, Sansom Institute of Health Research and School of Health Sciences, University of South Australia, Adelaide, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia., Jacobsson B; Department of Genetics and Bioinformatics, Area of Health Data and Digitalization, Institute of Public Health, Oslo, Norway.; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden., Jaddoe VW; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Johannesson M; Department of Economics, Stockholm School of Economics, Stockholm, Sweden., Jugessur A; Department of Genetics and Bioinformatics, Area of Health Data and Digitalization, Institute of Public Health, Oslo, Norway., Kähönen M; Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland., Kajantie E; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Children's Hospital, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.; Department of Obstetrics and Gynecology, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Kardia SL; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Keavney B; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK.; Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Koponen P; Health Monitoring Unit, National Institute for Health and Welfare, Helsinki, Finland., Kovacs P; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Kronenberg F; Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., La Bianca M; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Lachance G; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Iacono WG; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Lai S; Istituto di Ricerca Genetica e Biomedica, CMR, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland., Liewald DC; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Lindgren CM; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK.; Strangeways Research Laboratory, University of Cambridge, Cambridge, UK., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Luben R; Strangeways Research Laboratory, University of Cambridge, Cambridge, UK., Lucht M; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Luoto R; UKK Institute for Health Promotion,Tampere, Finland., Magnus P; Department of Genetics and Bioinformatics, Area of Health Data and Digitalization, Institute of Public Health, Oslo, Norway., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Martin NG; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Herston Brisbane, Queensland, Australia., McGue M; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA.; Danish Aging Research Center and Danish Twin Registry, Institute of Public Health, University of Southern Denmark, Odense, Denmark., McQuillan R; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Medland SE; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Herston Brisbane, Queensland, Australia., Meisinger C; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; MONICA/KORA Myocardial Infarction Registry, Central Hospital of Augsburg, Augsburg, Germany., Mellström D; Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Traglia M; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milan, Italy., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mitchell P; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney, Westmead, New South Wales, Australia., Montgomery GW; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Mook-Kanamori D; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.; Department of BESC, Epidemiology Section, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Nohr EA; Research Unit for Gynecology and Obstetrics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Ohlsson C; Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Olsen J; Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark., Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Paternoster L; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Penninx BW; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Perola M; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Peyser PA; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Pirastu M; Institute of Genetic and Biomedical Research, National Research Council, UOS of Sassari, Sassari, Italy., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Power C; Population, Policy and Practice, UCL Institute of Child Health, London, UK., Kaprio J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Raffel LJ; Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Räikkönen K; Institute of Behavioral Sciences, University of Helsinki, Helsinki, Finland., Raitakari O; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku and Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Ridker PM; Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Ring SM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Roll K; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Ruggiero D; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy., Rujescu D; Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany., Salomaa V; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Schlessinger D; Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA., Schmidt H; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, Austria., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Schupf N; Departments of Epidemiology and Psychiatry, Columbia University Medical Center, New York, New York, USA., Smit J; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Sorice R; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stöckl D; Departments of Epidemiology and Psychiatry, Columbia University Medical Center, New York, New York, USA., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig Maximilians Universität, Munich, Germany., Stumvoll M; Department of Medicine, University of Leipzig, Leipzig, Germany.; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Swertz MA; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Thorsteinsdottir U; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Thurik AR; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Montpellier Business School, Montpellier, France., Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Tung JY; 23andMe, Inc., Mountain View, California, USA., Uitterlinden AG; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Vaccargiu S; Institute of Genetic and Biomedical Research, National Research Council, UOS of Sassari, Sassari, Italy., Viikari J; Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland., Vitart V; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Vollenweider P; Department of Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., Vuckovic D; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Division of Experimental Genetics, Sidra, Doha, Qatar., Waage J; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Wagner GG; German Socio-Economic Panel Study (SOEP), Max Planck Institute for Human Development and Berlin University of Technology (TUB), Berlin, Germany., Wang JJ; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney, Westmead, New South Wales, Australia., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Willemsen G; Department of Biological Psychology, VU University, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Willeit J; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Wright AF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Zondervan KT; Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Endometriosis CaRe Centre, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Krueger RF; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Lee JJ; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Benjamin DJ; Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.; National Bureau of Economic Research, Cambridge, Massachusetts, USA., Cesarini D; Department of Economics, New York University, New York, New York, USA.; Research Institute for Industrial Economics, Stockholm, Sweden., Koellinger PD; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Complex Trait Genetics, VU University, Amsterdam, the Netherlands., den Hoed M; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Mills MC; Department of Sociology and Nuffield College, University of Oxford, Oxford, UK.
Publikováno v:
Nature genetics [Nat Genet] 2016 Dec; Vol. 48 (12), pp. 1462-1472. Date of Electronic Publication: 2016 Oct 31.
Autor:
Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, Kallela M, Freilinger TM, Ran C, Gordon SG, Stam AH, Steinberg S, Borck G, Koiranen M, Quaye L, Adams HH, Lehtimäki T, Sarin AP, Wedenoja J, Hinds DA, Buring JE, Schürks M, Ridker PM, Hrafnsdottir MG, Stefansson H, Ring SM, Hottenga JJ, Penninx BW, Färkkilä M, Artto V, Kaunisto M, Vepsäläinen S, Malik R, Heath AC, Madden PA, Martin NG, Montgomery GW, Kurki MI, Kals M, Mägi R, Pärn K, Hämäläinen E, Huang H, Byrnes AE, Franke L, Huang J, Stergiakouli E, Lee PH, Sandor C, Webber C, Cader Z, Muller-Myhsok B, Schreiber S, Meitinger T, Eriksson JG, Salomaa V, Heikkilä K, Loehrer E, Uitterlinden AG, Hofman A, van Duijn CM, Cherkas L, Pedersen LM, Stubhaug A, Nielsen CS, Männikkö M, Mihailov E, Milani L, Göbel H, Esserlind AL, Christensen AF, Hansen TF, Werge T, Kaprio J, Aromaa AJ, Raitakari O, Ikram MA, Spector T, Järvelin MR, Metspalu A, Kubisch C, Strachan DP, Ferrari MD, Belin AC, Dichgans M, Wessman M, van den Maagdenberg AM, Zwart JA, Boomsma DI, Smith GD, Stefansson K, Eriksson N, Daly MJ, Neale BM, Olesen J, Chasman DI, Nyholt DR, Palotie A
Publikováno v:
Nature genetics [Nat Genet] 2016 Sep 28; Vol. 48 (10), pp. 1296.
Autor:
Gormley P; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Anttila V; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Winsvold BS; FORMI, Oslo University Hospital, Oslo, Norway.; Department of Neurology, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Palta P; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Esko T; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA., Pers TH; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Farh KH; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Illumina, San Diego, California, USA., Cuenca-Leon E; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Pediatric Neurology, Vall d'Hebron Research Institute, Barcelona, Spain., Muona M; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Folkhälsan Institute of Genetics, Helsinki, Finland.; Neuroscience Center, University of Helsinki, Helsinki, Finland.; Molecular Neurology Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland., Furlotte NA; 23andMe, Inc., Mountain View, California, USA., Kurth T; Institute of Public Health, Charité-Universitätsmedizin Berlin, Berlin, Germany.; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Ingason A; deCODE Genetics, Reykjavik, Iceland., McMahon G; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Ligthart L; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands., Terwindt GM; Department of Neurology, Leiden University Medical Centre, Leiden, the Netherlands., Kallela M; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland., Freilinger TM; Department of Neurology and Epileptology, Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany., Ran C; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden., Gordon SG; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Stam AH; Department of Neurology, Leiden University Medical Centre, Leiden, the Netherlands., Steinberg S; deCODE Genetics, Reykjavik, Iceland., Borck G; Institute of Human Genetics, Ulm University, Ulm, Germany., Koiranen M; Center for Life Course Epidemiology and Systems Medicine, University of Oulu, Oulu, Finland., Quaye L; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Adams HH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Radiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, School of Medicine, University of Tampere, Tampere, Finland., Sarin AP; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Wedenoja J; Department of Public Health, University of Helsinki, Helsinki, Finland., Hinds DA; 23andMe, Inc., Mountain View, California, USA., Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Schürks M; Department of Neurology, University Duisburg-Essen, Essen, Germany., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Hrafnsdottir MG; Landspitali University Hospital, Reykjavik, Iceland., Stefansson H; deCODE Genetics, Reykjavik, Iceland., Ring SM; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands., Penninx BW; Department of Psychiatry, VU University Medical Centre, Amsterdam, the Netherlands., Färkkilä M; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland., Artto V; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland., Kaunisto M; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Vepsäläinen S; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland., Malik R; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany., Heath AC; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Madden PA; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Martin NG; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Montgomery GW; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Kurki MI; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Department of Neurosurgery, NeuroCenter, Kuopio University Hospital, Kuopio, Finland., Kals M; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Pärn K; Estonian Genome Center, University of Tartu, Tartu, Estonia., Hämäläinen E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Huang H; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Byrnes AE; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Franke L; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Huang J; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Stergiakouli E; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Lee PH; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Sandor C; MRC Functional Genomics Unit, Department of Physiology, Anatomy &Genetics, Oxford University, Oxford, UK., Webber C; MRC Functional Genomics Unit, Department of Physiology, Anatomy &Genetics, Oxford University, Oxford, UK., Cader Z; Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, UK.; Oxford Headache Centre, John Radcliffe Hospital, Oxford, UK., Muller-Myhsok B; Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Institute of Translational Medicine, University of Liverpool, Liverpool, UK., Schreiber S; Institute of Clinical Molecular Biology, Christian Albrechts University, Kiel, Germany., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Heikkilä K; Institute of Clinical Medicine, University of Helsinki, Helsinki, Finland., Loehrer E; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Cherkas L; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Pedersen LM; FORMI, Oslo University Hospital, Oslo, Norway., Stubhaug A; Department of Pain Management and Research, Oslo University Hospital, Oslo, Norway.; Medical Faculty, University of Oslo, Oslo, Norway., Nielsen CS; Department of Pain Management and Research, Oslo University Hospital, Oslo, Norway.; Department of Ageing and Health, Norwegian Institute of Public Health, Oslo, Norway., Männikkö M; Center for Life Course Epidemiology and Systems Medicine, University of Oulu, Oulu, Finland., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Göbel H; Kiel Pain and Headache Center, Kiel, Germany., Esserlind AL; Danish Headache Center, Department of Neurology, Rigshospitalet, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark., Christensen AF; Danish Headache Center, Department of Neurology, Rigshospitalet, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark., Hansen TF; Institute of Biological Psychiatry, Mental Health Center Sct. Hans, University of Copenhagen, Roskilde, Denmark., Werge T; Institute of Biological Psychiatry, MHC Sct. Hans, Mental Health Services Copenhagen, Copenhagen, Denmark.; Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen, Copenhagen, Denmark.; iPSYCH-The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark., Kaprio J; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Aromaa AJ; National Institute for Health and Welfare, Helsinki, Finland., Raitakari O; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Radiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Neurology, Erasmus University Medical Center, Rotterdam, the Netherlands., Spector T; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Järvelin MR; Center for Life Course Epidemiology and Systems Medicine, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPE) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Kubisch C; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Ferrari MD; Department of Neurology, Leiden University Medical Centre, Leiden, the Netherlands., Belin AC; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden., Dichgans M; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Wessman M; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Folkhälsan Institute of Genetics, Helsinki, Finland., van den Maagdenberg AM; Department of Neurology, Leiden University Medical Centre, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Centre, Leiden, the Netherlands., Zwart JA; FORMI, Oslo University Hospital, Oslo, Norway.; Department of Neurology, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Boomsma DI; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands., Smith GD; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Stefansson K; deCODE Genetics, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Eriksson N; 23andMe, Inc., Mountain View, California, USA., Daly MJ; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Neale BM; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Olesen J; Danish Headache Center, Department of Neurology, Rigshospitalet, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Nyholt DR; Statistical and Genomic Epidemiology Laboratory, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland, Australia., Palotie A; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Publikováno v:
Nature genetics [Nat Genet] 2016 Aug; Vol. 48 (8), pp. 856-66. Date of Electronic Publication: 2016 Jun 20.
Autor:
Nalls MA; 1] Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA. [2]., Pankratz N; 1] Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA. [2]., Lill CM; 1] Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany. [2] Department of Neurology, Focus Program Translational Neuroscience, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Do CB; 23andMe, Inc., Mountain View, California, USA., Hernandez DG; 1] Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA. [2] Reta Lila Weston Institute, University College London Institute of Neurology, Queen Square, London, UK., Saad M; 1] Department of Biostatistics, University of Washington, Seattle, Washington, USA. [2] INSERM, UMR 1043, Centre de Physiopathologie de Toulouse-Purpan, Toulouse, France. [3] Paul Sabatier University, Toulouse, France., DeStefano AL; 1] Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA. [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA. [3] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts, USA., Kara E; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK., Bras J; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK., Sharma M; 1] Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany. [2] Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Schulte C; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Keller MF; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA., Arepalli S; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA., Letson C; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA., Edsall C; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA., Stefansson H; deCODE Genetics, Reykjavík, Iceland., Liu X; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA., Pliner H; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA., Lee JH; The Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA., Cheng R; The Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA., Ikram MA; 1] Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands. [2] Department of Radiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands. [3] Department of Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Ioannidis JP; Stanford Prevention Research Center, Stanford University, Stanford, California, USA., Hadjigeorgiou GM; Neuroscience Unit, Department of Neurology, Faculty of Medicine, University of Thessaly, Larissa, Greece., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA., Martinez M; 1] INSERM, UMR 1043, Centre de Physiopathologie de Toulouse-Purpan, Toulouse, France. [2] Paul Sabatier University, Toulouse, France., Perlmutter JS; 1] Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA. [3] Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Goate A; 1] Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA. [3] Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA. [4] Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Marder K; 1] The Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA. [2] Gertrude H. Sergievsky Center, Columbia University Medical Center, New York, New York, USA. [3] Department of Neurology, Columbia University Medical Center, New York, New York, USA. [4] Department of Psychiatry, Columbia University Medical Center, New York, New York, USA., Fiske B; The Michael J. Fox Foundation for Parkinson's Research, New York, New York, USA., Sutherland M; Neuroscience Center, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA., Xiromerisiou G; 1] Neuroscience Unit, Department of Neurology, Faculty of Medicine, University of Thessaly, Larissa, Greece. [2] Department of Neurology, Papageorgiou Hospital, Thessaloniki, Greece., Myers RH; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA., Clark LN; 1] Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA. [2] The Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA., Stefansson K; deCODE Genetics, Reykjavík, Iceland., Hardy JA; Reta Lila Weston Institute, University College London Institute of Neurology, Queen Square, London, UK., Heutink P; Genome Biology for Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Chen H; Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle, North Carolina, USA., Wood NW; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK., Houlden H; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK., Payami H; New York State Department of Health Wadsworth Center, Albany, New York, USA., Brice A; 1] Sorbonne Université, UPMC Université Paris 06, UM 75, INSERM U1127, Institut du Cerveau et de la Moelle, Paris, France. [2] CNRS, UMR 7225, Paris, France. [3] Pitié-Salpêtrière Hospital, Department of Genetics and Cytogenetics, Paris, France., Scott WK; Department of Human Genetics, University of Miami School of Medicine, Miami, Florida, USA., Gasser T; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Bertram L; 1] Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany. [2] School of Public Health, Faculty of Medicine, The Imperial College of Science, Technology and Medicine, London, UK., Eriksson N; 23andMe, Inc., Mountain View, California, USA., Foroud T; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA., Singleton AB; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Publikováno v:
Nature genetics [Nat Genet] 2014 Sep; Vol. 46 (9), pp. 989-93. Date of Electronic Publication: 2014 Jul 27.
Autor:
Hinds DA; 23andMe, Inc., Mountain View, California, USA. dhinds@23andMe.com, McMahon G, Kiefer AK, Do CB, Eriksson N, Evans DM, St Pourcain B, Ring SM, Mountain JL, Francke U, Davey-Smith G, Timpson NJ, Tung JY
Publikováno v:
Nature genetics [Nat Genet] 2013 Aug; Vol. 45 (8), pp. 907-11. Date of Electronic Publication: 2013 Jun 30.