Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Seen-Ling Sim"'
Autor:
Kirat K. Chand, Jatin Patel, S. T. Bjorkman, Seen-Ling Sim, Stephanie M. Miller, Elliot Teo, Lara Jones, Jane Sun, Paul B. Colditz, Kiarash Khosrotehrani, Julie A. Wixey
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract The foetal brain is particularly vulnerable to the detrimental effects of foetal growth restriction (FGR) with subsequent abnormal neurodevelopment being common. There are no current treatments to protect the FGR newborn from lifelong neurol
Externí odkaz:
https://doaj.org/article/e8b09f839fb949199093e3762d588305
Autor:
Jilai Zhao, Jatin Patel, Simranpreet Kaur, Seen-Ling Sim, Ho Yi Wong, Cassandra Styke, Isabella Hogan, Sam Kahler, Hamish Hamilton, Racheal Wadlow, James Dight, Ghazaleh Hashemi, Laura Sormani, Edwige Roy, Mervin C. Yoder, Mathias Francois, Kiarash Khosrotehrani
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
How endothelial to mesenchymal transition is regulated in endovascular progenitors is unclear. Here, the authors show that blocking Sox9 expression in murine endovascular progenitors regulates this transition on skin wounding, affecting the size of s
Externí odkaz:
https://doaj.org/article/4916239cb44542b7875c762bd088d608
Autor:
Prudence Donovan, Jatin Patel, James Dight, Ho Yi Wong, Seen-Ling Sim, Valentine Murigneux, Mathias Francois, Kiarash Khosrotehrani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The contribution of endothelial progenitor cells to tumor angiogenesis is controversial. Here, the authors trace the lineage differentiation of endovascular progenitor cells and demonstrate their functional importance in tumor vascularization and pro
Externí odkaz:
https://doaj.org/article/b472c48355de4681b6ea5ebc4841da96
Autor:
Julie A. Wixey, S. T. Bjorkman, Lara Jones, Seen-Ling Sim, Jatin Patel, Paul B. Colditz, Jane Sun, Kirat K. Chand, Elliot Teo, Kiarash Khosrotehrani, Stephanie M. Miller
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-15 (2021)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
The foetal brain is particularly vulnerable to the detrimental effects of foetal growth restriction (FGR) with subsequent abnormal neurodevelopment being common. There are no current treatments to protect the FGR newborn from lifelong neurological di
Autor:
James Dight, Sam L. Kahler, Edwige Roy, Ho Yi Wong, Jatin Patel, Hamish Hamilton, Racheal Wadlow, Mathias Francois, Isabella Hogan, Seen Ling Sim, Simranpreet Kaur, Laura Sormani, Kiarash Khosrotehrani, Mervin C. Yoder, Jilai Zhao, Ghazaleh Hashemi, Cassandra Styke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
Endothelial to mesenchymal transition (EndMT) is a leading cause of fibrosis and disease, however its mechanism has yet to be elucidated. The endothelium possesses a profound regenerative capacity to adapt and reorganize that is attributed to a popul
Autor:
Seen-Ling Sim, Mathias Francois, Prudence Donovan, Jatin Patel, Kiarash Khosrotehrani, Ho Yi Wong, James Dight, Valentine Murigneux
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Tumor vascularization is a hallmark of cancer central to disease progression and metastasis. Current anti-angiogenic therapies have limited success prompting the need to better understand the cellular origin of tumor vessels. Using fate-mapping analy