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Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas
Autor:
Dan Ye, Kun Fan, Jingwen Zhang, Romela Irene Ramos, Haibo Zhang, Dave S.B. Hoon, Xiaowen Wang, Diego M. Marzese, Chunjie Li, Jian-Sheng Kang, Wei Hua
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
Ciliary neurotrophic factor receptor α subunit (CNTFRα) and CNTF play important roles in neuron survival, glial differentiation and brain tumor growth. However, the molecular mechanisms of CNTFRα regulation and its clinical significance in glioma