Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jonathan Hall"'
Autor:
Marcelo A. De Lira Mota, Tom Dunkley Jones, Nursufiah Sulaiman, Kirsty M. Edgar, Tatsuhiko Yamaguchi, Melanie J. Leng, Markus Adloff, Sarah E. Greene, Richard Norris, Bridget Warren, Grace Duffy, Jennifer Farrant, Masafumi Murayama, Jonathan Hall, James Bendle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Continental-scale expansion of the East Antarctic Ice Sheet during the Eocene-Oligocene Transition (EOT) is one of the largest non-linear events in Earth’s climate history. Declining atmospheric carbon dioxide concentrations and orbital va
Externí odkaz:
https://doaj.org/article/5b2552d28b5a4c4b8e1ccc7bc7e9a59e
Autor:
Evangelia Lekka, Aleksandra Kokanovic, Simone Mosole, Gianluca Civenni, Sandro Schmidli, Artur Laski, Alice Ghidini, Pavithra Iyer, Christian Berk, Alok Behera, Carlo V. Catapano, Jonathan Hall
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The Lin28/let-7 axis regulates metabolic pathways in normal and pathological contexts. Here the authors show that pharmacological inhibition of Lin28 protects against lipid accumulation in multiple preclinical models of nonalcoholic fatty liver disea
Externí odkaz:
https://doaj.org/article/4eb77299f3fe4991b4cc526dc0ff726c
Autor:
Malgorzata M. Duszczyk, Harry Wischnewski, Tamara Kazeeva, Rajika Arora, Fionna E. Loughlin, Christine von Schroetter, Ugo Pradère, Jonathan Hall, Constance Ciaudo, Frédéric H.-T. Allain
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The authors report an unusual mode of AU-rich RNA recognition by the RNA recognition motifs of DND1, a protein essential for germline development, in a 27.5 kDa NMR structure and provide additional insight on DND1 function from cell-based experiments
Externí odkaz:
https://doaj.org/article/e56fd6d7edc04090b57e471e350a8a05
Autor:
Anna Knörlein, Chris P. Sarnowski, Tebbe de Vries, Moritz Stoltz, Michael Götze, Ruedi Aebersold, Frédéric H.-T. Allain, Alexander Leitner, Jonathan Hall
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Although UV-induced cross-linking is a widely used method to study RNA-protein complexes, the cross-linking reactions are poorly understood. Here, the authors show that π-stacking interactions between nucleobases and aromatic amino acids play a key
Externí odkaz:
https://doaj.org/article/2cd6d485f0bf4ae2b1dfd7988cfbb5cd
Autor:
Carmela Garcia-Doval, Frank Schwede, Christian Berk, Jakob T. Rostøl, Ole Niewoehner, Oliver Tejero, Jonathan Hall, Luciano A. Marraffini, Martin Jinek
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Upon target RNA recognition, type III CRISPR-Cas systems produce cyclic oligoadenylates that activate effectors such as Csm6 ribonucleases. Here, Garcia-Doval et al. show that Enteroccocus italicus Csm6 degrades its cyclic hexa-AMP activator, and rep
Externí odkaz:
https://doaj.org/article/72db17b42bde4a3aab3bcb1de11e229a