Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Bruce A. Smith"'
Autor:
Chady H. Hakim, Sandeep R. P. Kumar, Dennis O. Pérez-López, Nalinda B. Wasala, Dong Zhang, Yongping Yue, James Teixeira, Xiufang Pan, Keqing Zhang, Emily D. Million, Christopher E. Nelson, Samantha Metzger, Jin Han, Jacqueline A. Louderman, Florian Schmidt, Feng Feng, Dirk Grimm, Bruce F. Smith, Gang Yao, N. Nora Yang, Charles A. Gersbach, Shi-jie Chen, Roland W. Herzog, Dongsheng Duan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The Cas9-specific T cell response has been speculated to impair CRISPR therapy. Here, the authors show that local and systemic AAV CRISPR therapy induces cytotoxic killing and eliminates rescued dystrophin in canine models of Duchenne muscular dystro
Externí odkaz:
https://doaj.org/article/fa789cec57864e868cf64db8cae359c5
Autor:
Jonathan Marable, Damien Ruiz, Anil K. Jaiswal, Ritankar Bhattacharya, Robert Pantazes, Payal Agarwal, Amol S. Suryawanshi, Deepa Bedi, Amarjit Mishra, Bruce F. Smith, Maninder Sandey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Cancer is the leading cause of death in the geriatric dog population. Currently, the use of immune checkpoint inhibitors (ICIs) such as anti-CTLA4 antibodies has markedly improved the prognosis of several cancers in their advanced stages. Ho
Externí odkaz:
https://doaj.org/article/a1254a4909ce448fbb10ccd72cd4ca3b