Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Li, Yuxin"'
Autor:
Shi, Yue, Park, Kyoung Sun, Kim, Seung Hyun, Yu, Jia, Zhao, Kaixuan, Yu, Lina, Oh, Ki Wook, Lee, Kayoung, Kim, Jaeyoon, Chaggar, Kanchan, Li, Yuxin, Dolphin, Annette C., Catterall, William A., Ryu, Sung Ho, Yang, Shao-Nian, Berggren, Per-Olof
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We provide evidence of a mechanistic link between ALS and T2DM. Our data show that a subgroup of ALS-T2DM patients have sera that enhance CaV1 channel-mediated Ca2+ influx and exaggerate [Ca2+]i. These effects occur because the sera acco
Autor:
Yu, Jia, Shi, Yue, Zhao, Kaixuan, Yang, Guang, Yu, Lina, Li, Yuxin, Andersson, Eva-Marie, Ämmälä, Carina, Yang, Shao-Nian, Berggren, Per-Olof
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We reveal that increased expression of CaV3.1 channels in rat islets selectively impairs first-phase glucose-stimulated insulin secretion. This deterioration is recapitulated in human islets. Its causal role in diabetes development is cl
Autor:
Yu J; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, SE-171 76 Stockholm, Sweden; Jia.Yu@ki.se Shao-Nian.Yang@ki.se Per-Olof.Berggren@ki.se., Shi Y; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, SE-171 76 Stockholm, Sweden., Zhao K; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, SE-171 76 Stockholm, Sweden., Yang G; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, SE-171 76 Stockholm, Sweden.; Institute of Pharmacology, Jilin Academy of Traditional Chinese Medicine, Changchun 130021, China., Yu L; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, SE-171 76 Stockholm, Sweden., Li Y; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China., Andersson EM; Bioscience, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 38 Mölndal, Gothenburg, Sweden., Ämmälä C; Bioscience, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 38 Mölndal, Gothenburg, Sweden., Yang SN; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, SE-171 76 Stockholm, Sweden; Jia.Yu@ki.se Shao-Nian.Yang@ki.se Per-Olof.Berggren@ki.se.; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China., Berggren PO; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, SE-171 76 Stockholm, Sweden; Jia.Yu@ki.se Shao-Nian.Yang@ki.se Per-Olof.Berggren@ki.se.; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu 610041, China.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 07; Vol. 117 (1), pp. 448-453. Date of Electronic Publication: 2019 Dec 23.
Autor:
Shi Y; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital L1, SE-171 76 Stockholm, Sweden., Park KS; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang 37673, Korea., Kim SH; Department of Neurology, Hanyang University Hospital, Seoul 04763, Korea., Yu J; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital L1, SE-171 76 Stockholm, Sweden., Zhao K; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital L1, SE-171 76 Stockholm, Sweden., Yu L; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital L1, SE-171 76 Stockholm, Sweden., Oh KW; Department of Neurology, Hanyang University Hospital, Seoul 04763, Korea., Lee K; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang 37673, Korea., Kim J; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang 37673, Korea., Chaggar K; Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, United Kingdom., Li Y; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China., Dolphin AC; Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, United Kingdom., Catterall WA; Department of Pharmacology, School of Medicine, University of Washington, Seattle, WA 98195-7280., Ryu SH; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang 37673, Korea., Yang SN; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital L1, SE-171 76 Stockholm, Sweden.; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, China., Berggren PO; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital L1, SE-171 76 Stockholm, Sweden.; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang 37673, Korea.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 637553.; Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL 33136.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Dec 26; Vol. 116 (52), pp. 26816-26822. Date of Electronic Publication: 2019 Dec 11.
Autor:
Bai B; Departments of Structural Biology and Developmental Neurobiology and St. Jude Proteomics Facility, St. Jude Children's Research Hospital, Memphis, TN 38105., Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, Diner I, Heilman CJ, Rees HD, Wu H, Lin L, Szulwach KE, Gearing M, Mufson EJ, Bennett DA, Montine TJ, Seyfried NT, Wingo TS, Sun YE, Jin P, Hanfelt J, Willcock DM, Levey A, Lah JJ, Peng J
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Oct 08; Vol. 110 (41), pp. 16562-7. Date of Electronic Publication: 2013 Sep 10.
Autor:
Yang SN; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Stockholm, Sweden. shao-nian.yang@ki.se, Shi Y, Yang G, Li Y, Yu L, Shin OH, Bacaj T, Südhof TC, Yu J, Berggren PO
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Jul 24; Vol. 109 (30), pp. 12183-8. Date of Electronic Publication: 2012 Jul 09.