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pro vyhledávání: '"Li, Yuxin"'
Autor:
Yu, Jia, Shi, Yue, Zhao, Kaixuan, Yang, Guang, Yu, Lina, Li, Yuxin, Andersson, Eva-Marie, Ämmälä, Carina, Yang, Shao-Nian, Berggren, Per-Olof
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We reveal that increased expression of CaV3.1 channels in rat islets selectively impairs first-phase glucose-stimulated insulin secretion. This deterioration is recapitulated in human islets. Its causal role in diabetes development is cl