Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sandra Rayego-Mateos"'
Type IV Collagen and SOX9 Are Molecular Targets of BET Inhibition in Experimental Glomerulosclerosis
Autor:
José Luis Morgado-Pascual, Beatriz Suarez-Alvarez, Vanessa Marchant, Pamela Basantes, Pierre-Louis Tharaux, Alberto Ortiz, Carlos Lopez-Larrea, Marta Ruiz-Ortega, Sandra Rayego-Mateos
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 486
Progressive glomerulonephritis (GN) is characterized by an excessive accumulation of extracellular (ECM) proteins, mainly type IV collagen (COLIV), in the glomerulus leading to glomerulosclerosis. The current therapeutic approach to GN is suboptimal.
Autor:
Laura Marquez-Exposito, Lucia Tejedor-Santamaria, Floris A. Valentijn, Antonio Tejera-Muñoz, Sandra Rayego-Mateos, Vanessa Marchant, Raul R. Rodrigues-Diez, Irene Rubio-Soto, Sebastiaan N. Knoppert, Alberto Ortiz, Adrian M. Ramos, Roel Goldschmeding, Marta Ruiz-Ortega
Publikováno v:
Antioxidants; Volume 11; Issue 2; Pages: 301
Chronic kidney disease (CKD) can be considered as a clinical model for premature aging. However, non‐invasive biomarkers to detect early kidney damage and the onset of a senescent phenotype are lacking. Most of the preclinical senescence studies in
Autor:
Antonio Tejera-Muñoz, Laura Marquez-Exposito, Lucía Tejedor-Santamaría, Sandra Rayego-Mateos, Macarena Orejudo, Beatriz Suarez-Álvarez, Carlos López-Larrea, Marta Ruíz-Ortega, Raúl R. Rodrigues-Díez
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 375
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 375, p 375 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 375, p 375 (2022)
The cellular communication network factor 2 (CCN2/CTGF) has been traditionally described as a mediator of the fibrotic responses induced by other factors including the transforming growth factor β (TGF-β). However, several studies have defined a di
Autor:
Emilio González Parra, Sebastian Mas, José Luis Morgado-Pascual, Alberto Ruiz Priego, Sandra Rayego-Mateos, Marta Ruiz-Ortega
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7189, p 7189 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7189, p 7189 (2021)
BACKGROUND: Bisphenol A (BPA) is a ubiquitous environmental toxin that accumulates in chronic kidney disease (CKD). Our aim was to explore the effect of chronic exposition of BPA in healthy and injured kidney investigating potential mechanisms involv