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Autor:
Aldo R. Boccaccini, Sandra Rother, Matthias Schnabelrauch, Vera Hintze, Norbert Halfter, Kai Zheng, Lysann M. Kroschwald, Michael C. Hacker, Stephanie Möller, Felix Allerdt, Anne Bernhardt, Christiane Heinemann, Stefan Rammelt, Iram Maqsood
Publikováno v:
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12819
International Journal of Molecular Sciences, Vol 22, Iss 12819, p 12819 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12819, p 12819 (2021)
International Journal of Molecular Sciences
The present study analyzes the capacity of collagen (coll)/sulfated glycosaminoglycan (sGAG)-based surface coatings containing bioactive glass nanoparticles (BGN) in promoting the osteogenic differentiation of human mesenchymal stroma cells (hMSC). P
Autor:
Fabian Westhauser, Aldo R. Boccaccini, Marcela Arango Ospina, Arash Moghaddam, Sarah I. Schmitz, Frederike Hohenbild
Publikováno v:
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12703
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12703, p 12703 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12703, p 12703 (2021)
Magnesium (Mg2+) is known to play a crucial role in mineral and matrix metabolism of bone tissue and is thus increasingly considered in the field of bone tissue engineering. Bioactive glasses (BGs) offer the promising possibility of the incorporation
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10335, p 10335 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10335, p 10335 (2021)
Cardiovascular diseases are the leading cause of death worldwide. A completely autologous treatment can be achieved by using elastogenic mesenchymal stem cell (MSC)-derived smooth muscle cells (SMC) at the affected tissue site of vascular diseases su
Autor:
Yann D Ladner, Mauro Alini, Nicholas R. Forsyth, Alicia J. El Haj, Graziana Monaco, Martin J. Stoddart
Publikováno v:
Cells
Volume 10
Issue 8
Cells, Vol 10, Iss 2165, p 2165 (2021)
Cells, 10 (8)
Volume 10
Issue 8
Cells, Vol 10, Iss 2165, p 2165 (2021)
Cells, 10 (8)
In the field of tissue engineering, progress has been made towards the development of new treatments for cartilage and bone defects. However, in vitro culture conditions for human bone marrow mesenchymal stromal cells (hBMSCs) have not yet been fully
Publikováno v:
Cells
Volume 10
Issue 8
Cells, Vol 10, Iss 2089, p 2089 (2021)
Volume 10
Issue 8
Cells, Vol 10, Iss 2089, p 2089 (2021)
In Notch signaling, the Jagged1-Notch3 ligand-receptor pairing is implicated for regulating the phenotype maturity of vascular smooth muscle cells. However, less is known about the role of Jagged1 presentation strategy in this regulation. In this stu
Autor:
Ping Ma, Linsheng Zhan, Qianqian Zhou, Yulong Zhang, Lei Zhang, Jing Yang, Liping Lv, Sujing Sun, Min Liu, Lei Gao, Xiaohui Wang
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7445, p 7445 (2021)
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7445, p 7445 (2021)
The effective cryopreservation of mesenchymal stem cells (MSCs) is indispensable to the operation of basic research and clinical transplantation. The prevalent protocols for MSC cryopreservation utilize dimethyl sulfoxide (DMSO), which is easily perm
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7086, p 7086 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7086, p 7086 (2021)
Mesenchymal stem cells (MSC) are potentially a good material for transplantation in many diseases, including neurodegenerative diseases. The main problem with using them is the low percentage of surviving cells after the transplant procedure and the
Publikováno v:
Cells
Volume 10
Issue 6
Cells, Vol 10, Iss 1463, p 1463 (2021)
Volume 10
Issue 6
Cells, Vol 10, Iss 1463, p 1463 (2021)
This study aims to obtain sufficient corneal endothelial cells for regenerative application. We examined the combinatory effects of Rho-associated kinase (ROCK) inhibitor Y-27632 and mesenchymal stem cell-derived conditioned medium (MSC-CM) on the pr
Autor:
Rosario Giuffrida, Gabriella Lupo, Florinda Gennuso, Carmelina Daniela Anfuso, Giovanni Giurdanella, Anna Longo, Debora Lo Furno, Giuliana Mannino
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4604, p 4604 (2021)
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4604, p 4604 (2021)
A pericyte-like differentiation of human adipose-derived mesenchymal stem cells (ASCs) was tested in in vitro experiments for possible therapeutic applications in cases of diabetic retinopathy (DR) to replace irreversibly lost pericytes. For this pur
Autor:
Andrea Svoradová, Jaromír Vašíček, Marián Tomka, Mária Tirpáková, Peter Chrenek, Miroslav Bauer, Alexander V. Makarevich, Andrej Baláži
Publikováno v:
Genes
Volume 12
Issue 3
Genes, Vol 12, Iss 431, p 431 (2021)
Volume 12
Issue 3
Genes, Vol 12, Iss 431, p 431 (2021)
Although the rabbit is a frequently used biological model, the phenotype of rabbit adipose-derived mesenchymal stem cells (rAT-MSCs) is not well characterized. One of the reasons is the absence of specific anti-rabbit antibodies. The study aimed to c