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Publikováno v:
Cells
Volume 10
Issue 11
Cells, Vol 10, Iss 3038, p 3038 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 3038, p 3038 (2021)
Cell lines are widely used as in vitro model systems and substitute for animal experiments. The frequently used Caco-2 cell line is considered to reflect characteristics of differentiated intestinal epithelium. However, the need to culture the cells
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 10972, p 10972 (2021)
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 10972, p 10972 (2021)
MicroRNAs are known to play a critical role in skeletal myogenesis and maintenance, and cofilin-2 (CFL2) is necessary for actin cytoskeleton dynamics and myogenic differentiation. Nonetheless, target molecules and the modes of action of miRNAs, espec
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10335, p 10335 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10335, p 10335 (2021)
Cardiovascular diseases are the leading cause of death worldwide. A completely autologous treatment can be achieved by using elastogenic mesenchymal stem cell (MSC)-derived smooth muscle cells (SMC) at the affected tissue site of vascular diseases su
Autor:
Arend W Overeem, Yolanda W Chang, Christian Freund, Celine M Roelse, Susana M. Chuva de Sousa Lopes, Xueying Fan
Publikováno v:
Cells
Volume 10
Issue 9
CELLS
Cells, Vol 10, Iss 2400, p 2400 (2021)
Cells, 10(9). MDPI
Volume 10
Issue 9
CELLS
Cells, Vol 10, Iss 2400, p 2400 (2021)
Cells, 10(9). MDPI
Human pluripotent stem cells (hPSCs) are not only a promising tool to investigate differentiation to many cell types, including the germline, but are also a potential source of cells to use for regenerative medicine purposes in the future. However, c
Publikováno v:
Cells
Volume 10
Issue 8
Cells, Vol 10, Iss 2089, p 2089 (2021)
Volume 10
Issue 8
Cells, Vol 10, Iss 2089, p 2089 (2021)
In Notch signaling, the Jagged1-Notch3 ligand-receptor pairing is implicated for regulating the phenotype maturity of vascular smooth muscle cells. However, less is known about the role of Jagged1 presentation strategy in this regulation. In this stu
Publikováno v:
Cells; Volume 10; Issue 8; Pages: 1870
Cells
Cells, Vol 10, Iss 1870, p 1870 (2021)
Cells
Cells, Vol 10, Iss 1870, p 1870 (2021)
Rhabdomyosarcoma (RMS), is the most frequent soft tissue tumor in children that originates from disturbances in differentiation process. Mechanisms leading to the development of RMS are still poorly understood. Therefore, by analysis of two RMS RH30
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7086, p 7086 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7086, p 7086 (2021)
Mesenchymal stem cells (MSC) are potentially a good material for transplantation in many diseases, including neurodegenerative diseases. The main problem with using them is the low percentage of surviving cells after the transplant procedure and the
Autor:
Shimeng Qiu, Mima Shinji, Tadahiro Hashita, Yaling Li, Tamihide Matsunaga, Takahiro Iwao, Yuki Imakura
Publikováno v:
Cells
Volume 10
Issue 4
Cells, Vol 10, Iss 812, p 812 (2021)
Volume 10
Issue 4
Cells, Vol 10, Iss 812, p 812 (2021)
The endoderm, differentiated from human induced pluripotent stem cells (iPSCs), can differentiate into the small intestine and liver, which are vital for drug absorption and metabolism. The development of human iPSC-derived enterocytes (HiEnts) and h
Publikováno v:
Cells
Volume 9
Issue 12
Cells, 9(12):2633. MDPI
Cells, Vol 9, Iss 2633, p 2633 (2020)
Cells, 9(12). MDPI Multidisciplinary Digital Publishing Institute
Volume 9
Issue 12
Cells, 9(12):2633. MDPI
Cells, Vol 9, Iss 2633, p 2633 (2020)
Cells, 9(12). MDPI Multidisciplinary Digital Publishing Institute
The flow cytometric detection of intracellular (IC) signaling proteins and transcription factors (TFs) will help to elucidate the regulation of B cell survival, proliferation and differentiation. However, the simultaneous detection of signaling prote
Autor:
Péter Hollósi, Bálint Péterfia, László Szilák, Enikő Tátrai, Katalin Karaszi, Lóránd Váncza, Tibor Szarvas, Ilona Kovalszky, Katalin Dobos, Péter Tátrai, Sándor Paku
Publikováno v:
Biomolecules
Volume 10
Issue 10
Biomolecules, Vol 10, Iss 1356, p 1356 (2020)
Volume 10
Issue 10
Biomolecules, Vol 10, Iss 1356, p 1356 (2020)
Syndecan-1 is a transmembrane heparan sulfate proteoglycan which is indispensable in the structural and functional integrity of epithelia. Normal hepatocytes display strong cell surface expression of syndecan-1
however, upon malignant transforma
however, upon malignant transforma