Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Martin Schreiber"'
Autor:
Katja Zappe, Antonio Kopic, Alexandra Scheichel, Ann-Katrin Schier, Lukas Emanuel Schmidt, Yasmin Borutzki, Heidi Miedl, Martin Schreiber, Theresa Mendrina, Christine Pirker, Georg Pfeiler, Stefan Hacker, Werner Haslik, Dietmar Pils, Andrea Bileck, Christopher Gerner, Samuel Meier-Menches, Petra Heffeter, Margit Cichna-Markl
Publikováno v:
Cells, Vol 12, Iss 11, p 1462 (2023)
The ABC transporter ABCA7 has been found to be aberrantly expressed in a variety of cancer types, including breast cancer. We searched for specific epigenetic and genetic alterations and alternative splicing variants of ABCA7 in breast cancer and inv
Externí odkaz:
https://doaj.org/article/63047c16006448ee8480b8d570179a49
Autor:
Heidi Miedl, Denise Oswald, Isabella Haslinger, Manuela Gstoettner, René Wenzl, Katharina Proestling, Christian Schneeberger, Iveta Yotova, Martin Schreiber
Publikováno v:
Cells, Vol 12, Iss 4, p 515 (2023)
Estrogen receptor α (ERα), encoded by the ESR1 gene, is a key prognostic and predictive biomarker firmly established in routine diagnostics and as a therapeutic target of breast cancer, and it has a central function in breast cancer biology. Geneti
Externí odkaz:
https://doaj.org/article/3a8670627b7f4d9a97eef30b65d3a819
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 1825 (2023)
Telomerase reverse transcriptase (TERT) plays a key role in the maintenance of telomere DNA length. The rs10069690 single nucleotide variant, located in intron 4 of TERT, was found to be associated with telomere length and the risk of estrogen recept
Externí odkaz:
https://doaj.org/article/99d2345cc9a845cd8685ca8402ddbd04
Autor:
Katja Zappe, Christine Pirker, Heidi Miedl, Martin Schreiber, Petra Heffeter, Georg Pfeiler, Stefan Hacker, Werner Haslik, Sabine Spiegl-Kreinecker, Margit Cichna-Markl
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12527 (2021)
Due to its cost-efficiency, high resolution melting (HRM) analysis plays an important role in genotyping of candidate single nucleotide polymorphisms (SNPs). Studies indicate that HRM analysis is not only suitable for genotyping individual SNPs, but
Externí odkaz:
https://doaj.org/article/99f9b8069d9140af89247b2e53ecf2fe
Autor:
Karin Zins, Barbara Frech, Eva Taubenschuss, Christian Schneeberger, Dietmar Abraham, Martin Schreiber
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 12, Pp 29643-29653 (2015)
Like other RECQ helicases, WRN/RECQL2 plays a crucial role in DNA replication and the maintenance of genome stability. Inactivating mutations in RECQL2 lead to Werner syndrome, a rare autosomal disease associated with premature aging and an increased
Externí odkaz:
https://doaj.org/article/5c5be7d810c244c2b237681fafe67c6f
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 1, Pp 712-724 (2014)
The CYP19 gene encodes aromatase, an enzyme catalyzing the conversion of androgens to estrogens. Studies analyzing associations between single nucleotide polymorphisms in CYP19 and breast cancer risk have shown inconsistent results. The rs10046 polym
Externí odkaz:
https://doaj.org/article/272cc54f396e46e5913ed2b2f94b0d13
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 509 (2019)
SNP309T>G (rs2279744) and SNP285G>C (rs117039649) in the MDM2 promoter are thought to have opposite effects on the binding of transcription factor SP1 (specificity protein 1), and consequently on MDM2 expression, p53 levels, cancer risk, age at onset
Externí odkaz:
https://doaj.org/article/03c01312c2d6490c98fb447137db6a69
Autor:
Dana Muin, Lisa Ehart, Barbara Frech, Eva Taubenschuß, Maurice Mogg, Erika Marton, Martin Schreiber
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 8, Pp 15376-15385 (2013)
The L10P single nucleotide polymorphism (SNP) is located in the signal sequence of the transforming growth factor β1 (TGFβ1) gene. The proline-encoding (Pro-) allele of this SNP has been associated with an increased breast cancer risk, which has be
Externí odkaz:
https://doaj.org/article/db5101c5c70c4808931b555b08cae7b4
Autor:
Christoph Riesinger, Arash Bakhtiari, Martin Schreiber, Philipp Neumann, Hans-Joachim Bungartz
Publikováno v:
Computation, Vol 5, Iss 4, p 48 (2017)
Heterogeneous clusters are a widely utilized class of supercomputers assembled from different types of computing devices, for instance CPUs and GPUs, providing a huge computational potential. Programming them in a scalable way exploiting the maximal
Externí odkaz:
https://doaj.org/article/4192d61ebea245719bf8865b4da455cc
Autor:
Stefan Hacker, Sabine Spiegl-Kreinecker, Margit Cichna-Markl, Werner Haslik, Georg Pfeiler, Katja Zappe, Christine Pirker, Martin Schreiber, Petra Heffeter, Heidi Miedl
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12527, p 12527 (2021)
Due to its cost-efficiency, high resolution melting (HRM) analysis plays an important role in genotyping of candidate single nucleotide polymorphisms (SNPs). Studies indicate that HRM analysis is not only suitable for genotyping individual SNPs, but