Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bradley T. Andresen"'
Autor:
Md Abdullah Shamim, Ayaz Shahid, Pabitra K. Sardar, Steven Yeung, Jeremiah Reyes, Jenny Kim, Cyrus Parsa, Robert Orlando, Jeffrey Wang, Kristen M. Kelly, Frank L. Meyskens, Bradley T. Andresen, Ying Huang
Publikováno v:
Nanomaterials, Vol 13, Iss 5, p 929 (2023)
The R-carvedilol enantiomer, present in the racemic mixture of the chiral drug carvedilol, does not bind to the β-adrenergic receptors, but exhibits skin cancer preventive activity. For skin delivery, R-carvedilol-loaded transfersomes were prepared
Externí odkaz:
https://doaj.org/article/3d025cf03a8f49b5987bc6fd3a863216
Autor:
Ayaz Shahid, Mengbing Chen, Carol Lin, Bradley T. Andresen, Cyrus Parsa, Robert Orlando, Ying Huang
Publikováno v:
Cancers, Vol 15, Iss 3, p 583 (2023)
The current study evaluated the effects of the β-blocker carvedilol on benzo(a)pyrene (B(a)P) and its active metabolite benzo(a)pyrene diol epoxide (BPDE)-induced lung toxicity, inflammation and carcinogenesis and explored the potential mechanisms.
Externí odkaz:
https://doaj.org/article/855f46154bf04520b2a3f47006c31d92
Autor:
Mengbing Chen, Md Abdullah Shamim, Ayaz Shahid, Steven Yeung, Bradley T. Andresen, Jeffrey Wang, Vijaykumar Nekkanti, Frank L. Meyskens, Kristen M. Kelly, Ying Huang
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1151 (2020)
The β-blocker carvedilol has been shown to prevent skin carcinogenesis in vitro and in vivo. Since systemic absorption of the β-blocker may cause cardiovascular disturbance, we developed a carvedilol loaded transfersome for skin-targeted delivery.
Externí odkaz:
https://doaj.org/article/ed49c9635b2845b5ab89447d4593eda0
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 798 (2020)
The β-blocker carvedilol prevents ultraviolet (UV)-induced skin cancer, but the mechanism is unknown. Since carvedilol possesses antioxidant activity, this study investigated whether carvedilol prevents oxidative photodamage of skin, a precursor eve
Externí odkaz:
https://doaj.org/article/5003f0ff19b24e89ac1f822b4b4550ea