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Publikováno v:
Cancers, Vol 13, Iss 920, p 920 (2021)
Cancers
Cancers
Simple Summary Natural products have continued to play an important role in new drug discovery with a considerable number of marketed drugs being derived from naturally occurring compounds, particularly in the area of cancer. Taccalonolides are a new
Autor:
Katrin Krützfeldt, Werner Baurecht, Susan Feyerabend, Hussein Sweiti, Andreas Huebner, Tim Mathes, Jochen Gleissner, Henrik Suttmann
Publikováno v:
Cancers, Vol 12, Iss 2550, p 2550 (2020)
Cancers
Volume 12
Issue 9
Cancers
Volume 12
Issue 9
Simple Summary We report the final results of a multicenter, prospective, 2-arm trial in a real world setting for patients with metastatic castration resistant prostate cancer. A number of 675 patients were allocated by center-based cluster-randomiza
Autor:
Daniel Pindak, Juraj Benca, Peter Celec, Gabriel Minarik, Paulina Gronesova, Jozef Mardiak, Michal Mego, Tatiana Sedlackova, Marian Karaba, Dana Cholujova, Katarina Kalavska
Publikováno v:
Cancers, Vol 12, Iss 2587, p 2587 (2020)
Cancers
Volume 12
Issue 9
Cancers
Volume 12
Issue 9
Simple Summary Nucleosomes composed of DNA and histone proteins enter the extracellular space and end eventually in the circulation when cells die. In blood plasma, they could represent a nonspecific marker of cell death, potentially useful for nonin
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 4666, p 4666 (2021)
Journal of Clinical Medicine
Journal of Clinical Medicine
Diabetic retinopathy (DR) is a complication of diabetes and one of the leading causes of vision loss worldwide. Despite extensive efforts to reduce visual impairment, the prevalence of DR is still increasing. The initial pathophysiology of DR include
Autor:
Shih-Ya Hung, E. Maruthi Prasad
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 14, Iss 717, p 717 (2021)
Pharmaceuticals, Vol 14, Iss 717, p 717 (2021)
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that currently has no cure, but treatments are available to improve PD symptoms and maintain quality of life. In 2020, about 10 million people worldwide were living with PD. In 19
Autor:
Kyoung Eun Lee, Seock-Ah Im, Moon Hee Lee, Jee Hyun Kim, Jong In Lee, Soohyeon Lee, Hee Kyung Ahn, Han Jo Kim, Hee Jun Kim, Yeon Hee Park, Gun Min Kim, Seok Yun Kang, Kyung Hae Jung, Su Jin Koh, In Hae Park
Publikováno v:
Cancers
Volume 12
Issue 11
Cancers, Vol 12, Iss 3265, p 3265 (2020)
Volume 12
Issue 11
Cancers, Vol 12, Iss 3265, p 3265 (2020)
In the era of CDK4/6 inhibitors in hormone receptor (HR)-positive, HER2-negative metastatic breast cancer, few trials have been specifically studied to compare quality of life between palbociclib plus endocrine therapy (ET) and cytotoxic chemotherapy
Autor:
Marco Cintoni, Maurizio Pompili, Emanuele Rinninella, Antonia Strippoli, Antonio Gasbarrini, Francesca Romana Ponziani, Giampaolo Tortora, Maria Cristina Mele, Pauline Raoul, Emilio Bria, Carmelo Pozzo
Publikováno v:
Nutrients, Vol 12, Iss 3101, p 3101 (2020)
Nutrients
Nutrients
In cancer patients, loss of muscle mass is significantly associated with low tolerability of chemotherapy and poor survival. Despite the great strides in the treatment of cancer, targeted therapies such as tyrosine kinase inhibitors (TKIs) could exac
Autor:
Imran Rizvi, Anne-Laure Bulin, Girgis Obaid, Mans Broekgaarden, Tayyaba Hasan, Shazia Bano, Ahmed Alkhateeb
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1401, p 1401 (2020)
Volume 12
Issue 6
Cancers, Vol 12, Iss 1401, p 1401 (2020)
Volume 12
Issue 6
Extensive desmoplasia is a hallmark of pancreatic ductal adenocarcinoma (PDAC), which frequently associates with treatment resistance. Recent findings indicate that a combination of photodynamic therapy and the multi-kinase inhibitor cabozantinib ach
Autor:
Giorgio Attinà, Anna Rita Fetoni, Stefano Mastrangelo, Michele Antonio Capozza, Palma Maurizi, Alberto Romano, Rolando Rolesi, Antonio Ruggiero, Silvia Triarico
Publikováno v:
Cancers, Vol 12, Iss 1266, p 1266 (2020)
Cancers
Cancers
Platinum compounds are a group of chemotherapeutic agents included in many pediatric and adult oncologic treatment protocols. The main platinum compounds are cisplatin, carboplatin, and oxaliplatin. Their use in clinical practice has greatly improved
Autor:
Yohei Shirakami, Hisataka Moriwaki, Takuji Tanaka, Naoki Watanabe, Ayumi Niwa, Masahito Shimizu, Takahiro Kochi, Takayuki Mori
Publikováno v:
Cancers, Vol 9, Iss 7, p 80 (2017)
Cancers
Cancers
Histamine and histamine receptors (Hrhs) have been identified as critical molecules during inflammation and carcinogenesis. This study was conducted to determine the effects of Hrh1-Hrh3 antagonists on inflammation-associated colorectal carcinogenesi