Zobrazeno 1 - 10
of 21
pro vyhledávání: ''
Autor:
Heekyong R. Bae, M. Eric Gershwin, Myung-Sook Choi, Seon Min Jeon, Suntae Kim, Howard A. Young, Eun-Young Kwon
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 208, p 208 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Obesity, a characteristic of metabolic syndrome, is also associated with chronic inflammation and the development of autoimmune diseases. However, the relationship between obesity and autoimmune diseases remains to be investigated in depth. Here, we
Autor:
Per Svenningsson, J. Wallin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5606, p 5606 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Parkinson’s disease (PD) is a neurodegenerative disorder where misfolded alpha-synuclein-enriched aggregates called Lewy bodies are central in pathogenesis. No neuroprotective or disease-modifying treatments are currently available. Parkinson’s d
Autor:
Wioleta Marut, Tiago Carvalheiro, Femke Bonte-Mineur, Jose M Pego-Reigosa, Beatriz Malvar-Fernandez, Carlos Rafael-Vidal, Timothy R D J Radstake, Maili Zimmermann, Maarten van der Kroef, Lorenzo Beretta, Samuel Garcia, Anneline C Hinrichs, Marc R. Kok, Ana P Lopes, Nila H. Servaas
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9544, p 9544 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences
Volume 21
Issue 24
Angiopoietin-2 (Ang-2), a ligand of the tyrosine kinase receptor Tie2, is essential for vascular development and blood vessel stability and is also involved in monocyte activation. Here, we examined the role of Ang-2 on monocyte activation in patient
Autor:
Marie-Paule Wautier, Jean-Luc Wautier
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6341, p 6341 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Inflammation is an old concept that has started to be considered as an important factor in infection and chronic diseases. The role of leukocytes, the plasmatic components, then of the mediators such as prostaglandins, cytokines, and, in recent decad
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3969, p 3969 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Severe asthma greatly affects patients’ quality of life. Major advances have occurred in the management of severe eosinophilic asthma the past few years due to the new targeted biological therapies. There are three anti-IL-5 mAbs, mepolizumab, resl
Autor:
Fabrizio Conti, Andrea Picchianti-Diamanti, Francesca Romana Spinelli, Maria Manuela Rosado, Bruno Laganà
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2638, p 2638 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Phosphodiesterases (PDEs) are a heterogeneous superfamily of enzymes which catalyze the degradation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). Among PDEs, PDE4 is the most w
Autor:
Satoshi Tanaka, Kazuyuki Furuta, Kazuhiko Yanai, Tadaho Nakamura, Hidenori Hayashi, Miho Kamei, Yukie Otani
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 4083 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 12
International Journal of Molecular Sciences
Volume 19
Issue 12
Accumulating evidence suggests that histamine synthesis induced in several types of tumor tissues modulates tumor immunity. We found that a transient histamine synthesis was induced in CD11b+Gr-1+ splenocytes derived from BALB/c mice transplanted wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e01dad6d1c34fbaf90ea2734613f67
https://doi.org/10.20944/preprints201811.0483.v1
https://doi.org/10.20944/preprints201811.0483.v1
Autor:
Luigi Laino, Cesare D’Amico, Salvatore Crimi, Giuseppe Troiano, Marco Cicciù, Roberto Lo Giudice, Luca Fiorillo, Floriana Lauritano, Alan S. Herford, Gabriele Cervino
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1908 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The purpose of the present study was to see if there is a correlation between the effect of interferons in crevicular fluid and periodontitis, evaluating literature. Interferon gamma (IFN-γ) is an immunoregulatory cytokine that, when activated by it
Autor:
Dianfeng Liu, Yalong Zeng, Xuan Yan, Juxiong Liu, Guangxin Chen, Shi-Yao Xu, Dongxue Yang, Bingxu Huang, Shoupeng Fu, Wei Wang, Chen Ju
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 10, p 2043 (2017)
International Journal of Molecular Sciences; Volume 18; Issue 10; Pages: 2043
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 10; Pages: 2043
International Journal of Molecular Sciences
The neuroprotective effects of Licochalcone A (Lico.A), a flavonoid isolated from the herb licorice, in Parkinson's disease (PD) have not been elucidated. The prominent pathological feature of PD is the loss of dopaminergic neurons. The crucial role
Publikováno v:
International Journal of Molecular Sciences
Volume 16
Issue 4
Pages 7413-7427
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES(16): 4
International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 7413-7427 (2015)
Volume 16
Issue 4
Pages 7413-7427
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES(16): 4
International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 7413-7427 (2015)
The purpose of this study was to clarify the correlation between microRNA-21 (miR-21) expression and inflammation in a herpes simplex virus (HSV)-induced Behçet’s Disease (BD) mouse model. miR-21 was compared between BD patients and healthy contro