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Autor:
Izolda Baskova, Alexandr Medvedev, Valentin A. Manuvera, Vassili N. Lazarev, Svetlana Nemirova, Pavel A. Bobrovsky
Publikováno v:
Current Issues in Molecular Biology
Volume 43
Issue 3
Pages 143-2081
Current Issues in Molecular Biology, Vol 43, Iss 143, Pp 2068-2081 (2021)
Volume 43
Issue 3
Pages 143-2081
Current Issues in Molecular Biology, Vol 43, Iss 143, Pp 2068-2081 (2021)
Leeches are amazing animals that can be classified as conditionally poisonous animals since the salivary cocktail they produce is injected directly into the victim, and its components have strictly defined biological purposes, such as preventing bloo
Autor:
Gary S. Laco
Publikováno v:
BioChem, Vol 1, Iss 15, Pp 190-209 (2021)
BioChem
Volume 1
Issue 3
Pages 15-209
BioChem
Volume 1
Issue 3
Pages 15-209
HIV-1 protease active site inhibitors are a key part of antiretroviral therapy, though resistance can evolve rendering therapy ineffective. Protease inhibitor resistance typically starts with primary mutations around the active site, which reduces in
Autor:
Manuela G. Neuman, Lawrence B. Cohen
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 139, Pp 2022-2035 (2021)
Current Issues in Molecular Biology
Volume 43
Issue 3
Pages 139-2035
Current Issues in Molecular Biology
Volume 43
Issue 3
Pages 139-2035
Hepatitis C virus (HCV)-induced liver disease contributes to chronic hepatitis. The immune factors identified in HCV include changes in the innate and adaptive immune system. The inflammatory mediators, known as “inflammasome”, are a consequence
Autor:
Natalja Predkele, Jānis Mednieks
Publikováno v:
Neurology International, Vol 13, Iss 48, Pp 487-496 (2021)
Neurology International
Neurology International
We present a case of a patient with positive N-methyl-D-aspartate receptor (NMDAR) IgG antibodies in their serum and cerebrospinal fluid (CSF) associated with neuroborreliosis. Clinically, the patient presented with symptoms of confusion, as well as
Autor:
Filippo de Marinis, Francesca Porta, Elena Guerini-Rocco, Carmine Valenza, Giuseppe Curigliano, Chiara Catania, Alessandra Rappa, Massimo Barberis, Giuseppe Viale
Publikováno v:
Current Oncology, Vol 28, Iss 292, Pp 3384-3392 (2021)
Current Oncology
Current Oncology
We present a case of a woman with epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma who received gefitinib for 2 years and obtained a partial response. The patient then developed liver metastasis and a breast lesion, displaying high
Autor:
Alan D. Kaye, Omar Viswanath, Shelby J. Patti, Yahya A. Ghaffar, Tony A. Hanna, Andrea G. Boyer, Ivan Urits, Carolina O. Ochoa, Haseeb A. Akuly, Elyse M. Cornett, Amber N. Edinoff, Adam M. Kaye
Publikováno v:
Neurology International, Vol 13, Iss 38, Pp 387-401 (2021)
Neurology International
Neurology International
Depression is the most prevalent psychiatric disorder in the world, affecting 4.4% of the global population. Despite an array of treatment modalities, depressive disorders remain difficult to manage due to many factors. Beginning with the introductio
Autor:
Alberto Castagna, Ciro Manzo
Publikováno v:
Clinics and Practice, Vol 11, Iss 55, Pp 404-409 (2021)
Clinics and Practice
Clinics and Practice
We report a 38-year-old female patient affected with anti-citrullinated protein antibody (ACPA)-positive rheumatoid arthritis (RA) who developed mild hemolytic anemia (Hb = 10.5 vs. >12 gr/dL), indolent oral ulceration, ANA (1:1280, homogeneous patte
Publikováno v:
Clinics and Practice, Vol 11, Iss 59, Pp 441-454 (2021)
Clinics and Practice
Clinics and Practice
Small-cell lung cancer (SCLC) is an aggressive subtype of lung cancer characterized by a rapid initial response and early development of resistance to systemic therapy and radiation. The management of SCLC significantly changed for the first time in
Autor:
C. Aaron Smith, Patricia Jumbo-Lucioni, Haddon Smith, Jimiece Thomas, Lori Coward, Maria De Luca, Gregory Gorman
Publikováno v:
Pathophysiology, Vol 28, Iss 20, Pp 307-319 (2021)
Pathophysiology
Volume 28
Issue 2
Pages 20-319
Pathophysiology
Volume 28
Issue 2
Pages 20-319
The use of angiotensin-converting enzyme inhibitors (ACEis) has been reported to reduce symptoms of cognitive decline in patients with Alzheimer’s disease (AD). Yet, the protective role of ACEis against AD symptoms is still controversial. 
Autor:
Elisa Mauro, Francesco Di Raimondo, Calogero Vetro, Cinzia Maugeri, Paolo Fiumara, Andrea Duminuco, Giuseppe Antonio Palumbo, Bruno Garibaldi, Rosario Foti
Publikováno v:
Hemato, Vol 2, Iss 20, Pp 347-352 (2021)
We report a case of a young patient suffering from very-high risk B-acute lymphoblastic leukemia (ALL) refractory to first-line therapy with early central nervous system relapse, sequentially treated with inotuzumab. At this timepoint, the patient sh