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Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11173, p 11173 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Stress and depression increase the risk of Type 2 Diabetes (T2D) development. Evidence demonstrates that the Glucocorticoid (GC) negative feedback is impaired (GC resistance) in T2D patients resulting in Hypothalamic-Pituitary-Adrenal (HPA) axis hype
Autor:
Umberto Gianelli, Marco Barella, Carlo Finelli, Giorgio Alberto Croci, Ramona Cassin, Elena Sabattini, Francesca Boggio, Gianluigi Reda, Loredana Pettine, Carlo Pescia
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 4809, p 4809 (2021)
Journal of Clinical Medicine
Volume 10
Issue 21
Journal of Clinical Medicine
Volume 10
Issue 21
High-risk Myelodysplastic syndromes (MDS) represent therapeutical challenges and are usually managed with hypomethylating agents such as azacitidine. Given the lack of data in the literature concerning azacitidine effects on bone marrow, we retrospec
Autor:
Hyoung Yool Lee, Kyoungwhan Back
Publikováno v:
Antioxidants, Vol 10, Iss 1728, p 1728 (2021)
Antioxidants
Volume 10
Issue 11
Pages: 1728
Antioxidants
Volume 10
Issue 11
Pages: 1728
Unlike animals, plants amply convert melatonin into 2-hydroxymelatonin (2-OHM) and cyclic 3-hydroxymelatonin (3-OHM) through the action of melatonin 2-hydroxylase (M2H) and melatonin 3-hydroxylase (M3H), respectively. Thus, the effects of exogenous m
Autor:
Laura Martin-Rodríguez, Raquel Largo, Gabriel Herrero-Beaumont, Aránzazu Mediero, Patricia Llamas-Granda
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11490, p 11490 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences
Volume 22
Issue 21
Semaphorin 4D (Sema4D) is a neurotrophin that is secreted by osteoclasts and binds to its receptor PlexinB1 on osteoblasts to inhibit their differentiation and function. Adenosine A2A activation inhibits osteoclast Sema4D-mediated secretion, diminish
Autor:
Ildikó Seres, A. Pusztai, Anita Szentpéteri, Szilvia Szamosi, Gabriella Szűcs, Éva Szekanecz, György Paragh, Edit Végh, Attila Hamar, Mariann Harangi, Andrea Domján, Sándor Szántó, Katalin Hodosi, Monika Czókolyová, Zoltán Szekanecz, Ágnes Horváth, György Kerekes
Publikováno v:
Biomolecules, Vol 11, Iss 1535, p 1535 (2021)
Biomolecules
Volume 11
Issue 10
Biomolecules
Volume 11
Issue 10
Background: Cardiovascular (CV) morbidity, mortality, and metabolic syndrome are associated with rheumatoid arthritis (RA) and ankylosing spondylitis (AS). Here, lipids and other metabolic markers in relation to vascular function and clinical markers
Autor:
Danuta Mańka, Barbara Radecka, Marlena Orlikowska, Małgorzata Foszczyńska-Kłoda, Emilia Filipczyk-Cisarż, Hanna Rogowska-Droś, Aleksandra Jackowska, Marek Gełej, Lubomir Bodnar, Mateusz Malik, Katarzyna Hetman, Maciej Michalak, Beata Kania-Zembaczyńska
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 5107, p 5107 (2021)
Journal of Clinical Medicine
Volume 10
Issue 21
Journal of Clinical Medicine
Volume 10
Issue 21
Sarcopenia is common in metastatic colorectal cancer (mCRC), increases the risk of treatment-related toxicity and reduces survival. Trifluridine/tipiracil (TT) chemotherapy significantly improved survival in refractory mCRC patients, but the prognost
Publikováno v:
Nutrients, Vol 13, Iss 3537, p 3537 (2021)
Nutrients
Volume 13
Issue 10
Nutrients
Volume 13
Issue 10
Anti-inflammatory agents that are safer and more effective than the currently used non-steroidal anti-inflammatory drugs are urgently needed. The dicaffeoylquinic acid (diCQA) isomer 4,5-diCQA exhibits antioxidant activity and various other health-pr
Autor:
Rumiko Matsuoka, Nanako Kawaguchi, Toshio Nakanishi, Kei Inai, Daiji Takeuchi, Nobuhisa Hagiwara, Yoji Nagashima, Akiko Seki, Keisuke Okita, Emiko Hayama, Yoshiyuki Furutani
Publikováno v:
Biology, Vol 10, Iss 1062, p 1062 (2021)
Biology; Volume 10; Issue 10; Pages: 1062
Biology
Biology; Volume 10; Issue 10; Pages: 1062
Biology
Simple Summary In this study, the induced pluripotent stem cell-derived cardiomyocyte model from a patient with long QT syndrome harboring a heterozygous Nav1.5 R1623Q mutation exhibited prolonged field potential duration corrected by Fridericia’s
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11644, p 11644 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Cardiovascular diseases are currently among the leading causes of morbidity and mortality in many developed countries. They are distinguished by chronic and latent development, a course with stages of worsening of symptoms and a period of improvement
Autor:
Hani A. Alfheeaid, Metab A Algeffari, Sami A. Althwab, H. A. Abdel-Rahman, Ibrahim S. Aleid, Hassan Barakat, Thamer Aljutaily, Hend F. Alharbi, Raghad M. Alhomaid
Publikováno v:
Nutrients, Vol 13, Iss 3499, p 3499 (2021)
Nutrients
Volume 13
Issue 10
Nutrients
Volume 13
Issue 10
This study was conducted to investigate the therapeutic effect of hydro-alcoholic extract of Spirulina platensis (SP), golden kiwifruit (Actinidia chinensis) flesh (KF), and golden kiwifruit peel (KP) individually or in combination (SFP) on indometha