Zobrazeno 1 - 10
of 62
pro vyhledávání: ''
Autor:
Li-Zhu Liao, Liang-Chun Lin, Chih-Ta Chen, Ya-Hui Chang, Nien-Chen Li, Bo-Shih Huang, Lu-Ping Chow
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 224, p 224 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Hepatocellular carcinoma is one of the most common cancer types worldwide. In cases of advanced-stage disease, sorafenib is considered the treatment of choice. However, resistance to sorafenib remains a major obstacle for effective clinical applicati
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3705, p 3705 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Poorly soluble environmental antigens, including carbon pollutants, are thought to play a role in the incidence of human sarcoidosis, a chronic inflammatory granulomatous disease of unknown causation. Currently, engineered carbon products such as mul
Autor:
Addanki P. Kumar, Shih-Bo Huang, Sridharan Jayamohan, Jianping Xie, Roble Bedolla, Izhar Singh Batth, Robert Reddick, Pawel A. Osmulski, Hiroshi Miyamoto, Rita Ghosh, I-Tien Yeh, Michelle R. Villarreal, Jingjing Gong, Brian Keppler, Divya Chakravarthy, Michael A. Liss, Paul Rivas
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1852, p 1852 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
2-Methoxyestradiol (2-ME2) possesses anti-tumorigenic activities in multiple tumor models with acceptable tolerability profile in humans. Incomplete understanding of the mechanism has hindered its development as an anti-tumorigenic compound. We have
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 741, p 741 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 2
International Journal of Molecular Sciences
Volume 22
Issue 2
Alzheimer&rsquo
s disease (AD), characterized by cognitive impairments, is considered to be one of the most widespread chronic neurodegenerative diseases worldwide. We recently introduced a novel therapeutic agent for AD treatment, the T-type ca
s disease (AD), characterized by cognitive impairments, is considered to be one of the most widespread chronic neurodegenerative diseases worldwide. We recently introduced a novel therapeutic agent for AD treatment, the T-type ca
Autor:
Sang Woo Park, So Young Kim, Reju George Thomas, In-Kyu Park, Jun Sung Lee, Yong Yeon Jeong, Myeong Ju Moon, Mi Sun Sung
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9297, p 9297 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences
Volume 21
Issue 23
Various neuroprotective agents have been studied for the treatment of retinal ganglion cell (RGC) diseases, but issues concerning the side effects of systemically administered drugs and the short retention time of intravitreally injected drugs limit
Autor:
Vlada S. Starinets, Kirill S. Tenkov, Konstantin N. Belosludtsev, Natalia V. Belosludtseva, Mikhail V. Dubinin, Eugeny Yu. Talanov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8763, p 8763 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences
Volume 21
Issue 22
Duchenne muscular dystrophy (DMD) is a severe hereditary disease caused by a lack of dystrophin, a protein essential for myocyte integrity. Mitochondrial dysfunction is reportedly responsible for DMD. This study examines the effect of glucocorticoid
Autor:
Sara Verdura, Ella Atlas, Ingrid Espinoza, Travis Vander Steen, Javier A. Menendez, Inderjit Mehmi, Luciano Vellon, Adriana Papadimitropoulou, Elisabet Cuyàs, Ruth Lupu
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7661, p 7661 (2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
International Journal of Molecular Sciences, 2020, vol. 21, núm. 20, p. 7661
Articles publicats (IdIBGi)
Menéndez Menéndez, Javier Abel Mehmi, Inderjit Papadimitropoulou, Adriana Steen, Travis Vander Cuyàs, Elisabet Verdura, Sara Espinoza, Ingrid Vellon, Luciano Atlas, Ella Lupu, Ruth 2020 Fatty Acid Synthase is a key enabler for endocrine resistance in Heregulin-overexpressing Luminal B-like breast cancer International Journal of Molecular Sciences 21 20 7661
DUGiDocs – Universitat de Girona
instname
International Journal of Molecular Sciences
Volume 21
Issue 20
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
International Journal of Molecular Sciences, 2020, vol. 21, núm. 20, p. 7661
Articles publicats (IdIBGi)
Menéndez Menéndez, Javier Abel Mehmi, Inderjit Papadimitropoulou, Adriana Steen, Travis Vander Cuyàs, Elisabet Verdura, Sara Espinoza, Ingrid Vellon, Luciano Atlas, Ella Lupu, Ruth 2020 Fatty Acid Synthase is a key enabler for endocrine resistance in Heregulin-overexpressing Luminal B-like breast cancer International Journal of Molecular Sciences 21 20 7661
DUGiDocs – Universitat de Girona
instname
International Journal of Molecular Sciences
Volume 21
Issue 20
HER2 transactivation by the HER3 ligand heregulin (HRG) promotes an endocrine-resistant phenotype in the estrogen receptor-positive (ER+) luminal-B subtype of breast cancer. The underlying biological mechanisms that link them are, however, incomplete
Autor:
Tadashi Namisaki, Norihisa Nishimura, Kosuke Kaji, Hitoshi Yoshiji, Akira Mitoro, Soichiro Saikawa, Takemi Akahane, Kei Moriya, Koh Kitagawa, Shinya Sato
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7588, p 7588 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences
Volume 21
Issue 20
Cholangiocarcinoma (CCA) is associated with high mortality rates because of its resistance to conventional gemcitabine-based chemotherapy. Hydroxy-methyl-glutaryl-coenzyme A reductase inhibitors (statins) reportedly exert anti-cancer effects in CCA a
Autor:
Emanuela Esposito, Salvatore Cuzzocrea, Michela Campolo, Giovanna Casili, Irene Paterniti, Marika Lanza, Alessio Ardizzone, Rosalba Siracusa, Sarah Adriana Scuderi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7486, p 7486 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences
Volume 21
Issue 20
Inflammation is a key element in the pathobiology of neurodegenerative diseases and sees the involvement of different neuronal and non-neuronal cells as players able to respond to inflammatory signals of immune origin. Palmitoylethanolamide (PEA) is
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6699, p 6699 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 18
International Journal of Molecular Sciences
Volume 21
Issue 18
Dihydromyricetin (DHY), a flavonoid component isolated from Ampelopsis grossedentata, exerts versatile pharmacological activities. However, the possible effects of DHY on diabetic vascular endothelial dysfunction have not yet been fully elucidated. I