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Autor:
Gregory A. Smith
Publikováno v:
Current Issues in Molecular Biology
Volume 41
Issue 1
Pages 171-220
Volume 41
Issue 1
Pages 171-220
Herpesviruses virions are large and complex structures that deliver their genetic content to nuclei upon entering cells. This property is not unusual as many other viruses including the adenoviruses, orthomyxoviruses, papillomaviruses, polyomaviruses
Autor:
Mari Hämäläinen, Antti Pemmari, Lauri J. Moilanen, Lauri Tuure, Riina Nieminen, Teemu Moilanen, E. Nummenmaa, Eeva Moilanen, Katriina Vuolteenaho
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 87, p 87 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Transient receptor potential ankyrin 1 (TRPA1) is a membrane-bound ion channel found in neurons, where it mediates nociception and neurogenic inflammation. Recently, we have discovered that TRPA1 is also expressed in human osteoarthritic (OA) chondro
Publikováno v:
Cells, Vol 10, Iss 52, p 52 (2021)
Cells
Cells
Many receptors for neurotransmitters, such as dopamine, norepinephrine, acetylcholine, and neuropeptides, belong to the superfamily of G protein-coupled receptors (GPCRs). A general model posits that GPCRs undergo two-step homologous desensitization:
Autor:
Ryota Chijimatsu, Takuya Ishimoto, Kenji Takami, Takayoshi Nakano, Kosuke Ebina, Atsushi Goshima, Takashi Kanamoto, Akira Miyama, Yuki Etani, Yasukazu Yonetani, Masayuki Hamada, Gensuke Okamura, Ken Nakata, Makoto Hirao, Hideki Yoshikawa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 300, p 300 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Synovial mesenchymal stem cell (SMSC) is the promising cell source of cartilage regeneration but has several issues to overcome such as limited cell proliferation and heterogeneity of cartilage regeneration ability. Previous reports demonstrated that
Autor:
Saeed Y. Al-ramadan, Fatma J. Al-Saeedi, A. M. Soliman, Gamal M. Bekhet, Maged E. Mohamed, Rebai Ben Ammar, Medhat Ahmed El-Naggar, Peramaiyan Rajendran
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 217, p 217 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
In this study, kaempferol (KFL) shows hepatoprotective activity against zearalenone (ZEA)-induced oxidative stress and its underlying mechanisms in in vitro and in vivo models were investigated. Oxidative stress plays a critical role in the pathophys
Autor:
Kailang Wu, Weiwei Ge, Keli Chen, Jianguo Wu, Mingfu Tian, Dingwen Hu, Feng Xiao, Wenbiao Wang, Pan Pan
Publikováno v:
Viruses, Vol 13, Iss 47, p 47 (2021)
Viruses
Viruses; Volume 13; Issue 1; Pages: 47
Viruses
Viruses; Volume 13; Issue 1; Pages: 47
SARS-CoV-2 is highly pathogenic in humans and poses a great threat to public health worldwide. Clinical data shows a disturbed type I interferon (IFN) response during the virus infection. In this study, we discovered that the nucleocapsid (N) protein
Publikováno v:
Biomolecules, Vol 11, Iss 19, p 19 (2021)
Biomolecules
Biomolecules
The leading cause of heart failure is cardiomyopathy and damage to the cardiomyocytes. Adult mammalian cardiomyocytes have the ability to regenerate, but this cannot wholly compensate for myocardial cell loss after myocardial injury. Studies have sho
Autor:
Sun-Hee Woo, Tran Nguyet Trinh
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 251, p 251 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
ATP is a major energy source in the mammalian cells, but it is an extracellular chemical messenger acting on P2 purinergic receptors. A line of evidence has shown that ATP is released from many different types of cells including neurons, endothelial
Autor:
Yohei Ohashi
Publikováno v:
Cells
Cells, Vol 10, Iss 3124, p 3124 (2021)
Cells, Vol 10, Iss 3124, p 3124 (2021)
Phosphatidylinositol-3-phosphate (PtdIns(3)P) is essential for cell survival, and its intracellular synthesis is spatially and temporally regulated. It has major roles in two distinctive cellular pathways, namely, the autophagy and endocytic pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7feed0749d09b1ff08778d0f425fcc
https://www.repository.cam.ac.uk/handle/1810/330784
https://www.repository.cam.ac.uk/handle/1810/330784
Publikováno v:
Cells, Vol 10, Iss 3362, p 3362 (2021)
Cells
Cells; Volume 10; Issue 12; Pages: 3362
Cells
Cells; Volume 10; Issue 12; Pages: 3362
The coordination of cell migration of immune cells is a critical aspect of the immune response to pathogens. Dendritic cells (DCs), the sentinels of the immune system, are exposed to complex tissue microenvironments with a wide range of stiffnesses.