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Autor:
Patrik Palacka, Anna Gvozdjáková, Zuzana Rausová, Jarmila Kucharská, Ján Slopovský, Jana Obertová, Daniel Furka, Samuel Furka, Keshav K. Singh, Zuzana Sumbalová
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 388, p 388 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 388
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 388
International Journal of Molecular Sciences
Mitochondrial bioenergetics reprogramming is an essential response of cells to stress. Platelets, an accessible source of mitochondria, have a crucial role in cancer development; however, the platelet mitochondrial function has not been studied in ur
Autor:
Takuya Kusakabe, Yasunobu Sawaji, Kenji Endo, Hidekazu Suzuki, Takamitsu Konishi, Asato Maekawa, Kazuma Murata, Kengo Yamamoto
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 371, p 371 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 371
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 371
International Journal of Molecular Sciences
The molecular mechanism of discogenic low back pain (LBP) involves nonphysiological nerve invasion into a degenerated intervertebral disc (IVD), induced by nerve growth factor (NGF). Selective cyclooxygenase (COX)-2 inhibitors are mainly used in the
Autor:
Estilla Zsófia Tóth, Felicia Gyöngyvér Szabó, Ágnes Kandrács, Noémi Orsolya Molnár, Gábor Nagy, Attila G. Bagó, Loránd Erőss, Dániel Fabó, Boglárka Hajnal, Bence Rácz, Lucia Wittner, István Ulbert, Kinga Tóth
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 202, p 202 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 202
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 202
International Journal of Molecular Sciences
Inhibitory neurons innervating the perisomatic region of cortical excitatory principal cells are known to control the emergence of several physiological and pathological synchronous events, including epileptic interictal spikes. In humans, little is
Autor:
Marina Yakovleva, Alexander Dontsov, Natalia Trofimova, Natalia Sakina, Alexey Kononikhin, Arseny Aybush, Alexander Gulin, Tatiana Feldman, Mikhail Ostrovsky
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 222, p 222 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 222
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 222
Age-related macular degeneration (AMD) is the primary cause of central blindness among the elderly. AMD is associated with progressive accumulation of lipofuscin granules in retinal pigment epithelium (RPE) cells. Lipofuscin contains bisretinoid fluo
Autor:
Lenka Kalinkova, Nataliia Nikolaieva, Bozena Smolkova, Sona Ciernikova, Karol Kajo, Vladimir Bella, Viera Horvathova Kajabova, Helena Kosnacova, Gabriel Minarik, Ivana Fridrichova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 103, p 103 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 103
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 103
Background: Dissemination of breast cancer (BC) cells through the hematogenous or lymphogenous vessels leads to metastatic disease in one-third of BC patients. Therefore, we investigated the new prognostic features for invasion and metastasis. Method
Autor:
Ramona Erber, Steffen Spoerl, Andreas Mamilos, Rosemarie Krupar, Arndt Hartmann, Matthias Ruebner, Juergen Taxis, Mareike Wittenberg, Torsten E. Reichert, Gerrit Spanier, Silvia Spoerl
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 87, p 87 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 87
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 87
International Journal of Molecular Sciences
Oral cancer often presents with aggressive behavior and a high risk of recurrence and metastasis. For oral squamous cell carcinoma (OSCC), which is the most frequent histological subtype, therapy strategies include surgery, radiation therapy, chemoth
Autor:
Jing-Jing Wei, Xiu-Juan Li, Wei Liu, Xue-Jun Chai, Xiao-Yan Zhu, Peng-Hao Sun, Feng Liu, Yong-Kang Zhao, Jun-Lang Huang, Ya-Fei Liu, Shan-Ting Zhao
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5881
The gut microbiota is increasingly considered to play a key role in human immunity and health. The aging process alters the microbiota composition, which is associated with inflammation, reactive oxygen species (ROS), decreased tissue function, and i
Epilepsy and Alzheimer’s disease (AD) incidence increases with age. There are reciprocal relationships between epilepsy and AD. Epilepsy is a risk factor for AD and, in turn, AD is an independent risk factor for developing epilepsy in old age, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8017f1384f4266c7029cb3b73a3133
https://doi.org/10.20944/preprints202203.0180.v1
https://doi.org/10.20944/preprints202203.0180.v1
Autor:
Kristen L. James, Erik R. Gertz, Catherine P. Kirschke, Hooman Allayee, Liping Huang, Mary E. Kable, John W. Newman, Charles B. Stephensen, Brian J. Bennett
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2074
International journal of molecular sciences, vol 24, iss 3
Volume 24
Issue 3
Pages: 2074
International journal of molecular sciences, vol 24, iss 3
Plasma trimethylamine n-oxide (TMAO) concentration increases in responses to feeding TMAO, choline, phosphatidylcholine, L-carnitine, and betaine but it is unknown whether concentrations change following a mixed macronutrient tolerance test (MMTT) wi
Autor:
Daniele Bottai, Raffaella Adami
Publikováno v:
International Journal of Molecular Sciences. 23:15209
While the U.S. Food and Drug Administration and the European Medicines Evaluation Agency have recently approved new drugs to treat spinal muscular atrophy 1 (SMA1) in young patients, they are mostly ineffective in older patients since many motor neur