Zobrazeno 1 - 10
of 20
pro vyhledávání: ''
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12670, p 12670 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin, is known to play important roles in inhibiting proliferation rate, inducing apoptosis, as well as hindering the metastasis and invasion of glioma cells, but the underlying mechanis
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12565, p 12565 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 22; Pages: 12565
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 22; Pages: 12565
International Journal of Molecular Sciences
Colony-stimulating factor 1 receptor (CSF-1R) acts as the receptor for colony stimulating factor 1, a cytokine that controls the production, differentiation, and function of macrophages. Prior studies showed cancer patients harboring germline CSF1R c
Autor:
Francisco Ruiz-Cabello, Francisco Perea, Hernani Gil-Julio, Natalia Aptsiauri, Jose Manuel Cozar, Antonio Rodriguez-Nicolas, Amanda Rocío González-Ramírez, Ángel Concha, Federico Garrido
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7248, p 7248 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 14
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
International Journal of Molecular Sciences
Volume 22
Issue 14
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Cancer eradication and clinical outcome of immunotherapy depend on tumor cell immunogenicity, including HLA class I (HLA-I) and PD-L1 expression on malignant cells, and on the characteristics of the tumor microenvironment, such as tumor immune infilt
Autor:
Udo Jeschke, Bastian Czogalla, Christina Kuhn, Martina Rahmeh, S Meister, Doris Mayr, Anna Hester, Tom Degenhardt, Sven Mahner, Anna Trebo, Nina Ditsch, Thomas Kolben, Elisa Schmoeckel
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2000, p 2000 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are involved in various immune cell-mediated diseases. Their role in cancer is poorly investigated, and research focusses on Siglec-expression on immune cells interacting with tumor cells. Thi
Autor:
Thorsten Schlomm, Jenny Roggisch, Anja Rabien, Ergin Kilic, Ralph M. Wirtz, Klaus Jung, Jan Gleichenhagen, Thomas Brüning, Minna Tervahartiala, Georg Johnen, Pekka Taimen, Adisch Kiani, Stefan Koch, Peter J. Boström, Thorsten H. Ecke, Frank Friedersdorff
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7420, p 7420 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 19
International Journal of Molecular Sciences
Volume 21
Issue 19
Objectives: Bladder cancer is a heterogeneous malignancy. Therefore, it is difficult to find single predictive markers. Moreover, most studies focus on either the immunohistochemical or molecular assessment of tumor tissues by next-generation sequenc
Autor:
Anastasia Makarevic, Andreas Unterberg, Andreas von Deimling, Christine Jungk, Rolf Warta, Steffen Dettling, Carmen Rapp, David E. Reuss, Amir Abdollahi, Christel Herold-Mende
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7801, p 7801 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences
Volume 21
Issue 20
Most gliomas are associated with a fatal prognosis and remain incurable because of their infiltrative growth. Consequently, the addition of immunotherapy to conventional therapy may improve patient outcomes. Here, we analyzed T-cell infiltration and,
Autor:
Bianka Gurbi, Diána Brauswetter, Gabor Halmos, József Murányi, Lilla Pethő, Kinga Pénzes, Gabriella Csík, Gábor Mező
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5027 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 20
International Journal of Molecular Sciences
Volume 20
Issue 20
Head and neck squamous cell carcinomas (HNSCC) have a high mortality rate, although several potential therapeutic targets have already been identified. Gonadotropin-releasing hormone receptor (GnRH-R) expression is less studied in head and neck cance
Autor:
Maya Jeje Schuang Lü, Linea Cecilie Melchior, Eric Santoni-Rugiu, Jesper Ravn, Jens Benn Sørensen, Jan Nyrop Jakobsen
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12868, p 12868 (2021)
Santoni-Rugiu, E, Lü, M J S, Jakobsen, J N, Melchior, L C, Ravn, J & Sørensen, J B 2021, ' Correlation of MET-receptor overexpression with MET gene amplification and patient outcome in malignant mesothelioma ', International Journal of Molecular Sciences, vol. 22, no. 23, 12868 . https://doi.org/10.3390/ijms222312868
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12868
International Journal of Molecular Sciences, Vol 22, Iss 12868, p 12868 (2021)
Santoni-Rugiu, E, Lü, M J S, Jakobsen, J N, Melchior, L C, Ravn, J & Sørensen, J B 2021, ' Correlation of MET-receptor overexpression with MET gene amplification and patient outcome in malignant mesothelioma ', International Journal of Molecular Sciences, vol. 22, no. 23, 12868 . https://doi.org/10.3390/ijms222312868
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12868
Thanks to clinically newly introduced inhibitors of the mesenchymal–epithelial transition (MET) receptor tyrosine-kinase, MET-gene copy number gain/amplification (MET-GCNG/GA) and increased expression of the MET protein are considered very promisin
Autor:
Erin M. O'Shaughnessy, M. Zamiri, Laura-María García-Vega, William Duffy, Keith Hussey, A. David Burden, Patricia Martin
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 6060, p 6060 (2021)
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 6060, p 6060 (2021)
Background: Psoriasis, a chronic inflammatory disease affecting 2–3% of the population, is characterised by epidermal hyperplasia, a sustained pro-inflammatory immune response and is primarily a T-cell driven disease. Previous work determined that
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 2129, p 2129 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 2129, p 2129 (2021)
CD8+ T cells are the main effector cells of anti-cancer immune response that can be regulated by various costimulatory and coinhibitory molecules, including members of the B7 family. B7 homolog 3 (B7-H3) appears as a promising marker for immunotherap