Zobrazeno 101 - 110
of 124
pro vyhledávání: ''
Autor:
Bai-Yan Li, Yonggang Cao, Jing Guo, Kai Fan, Xiaolei Li, Hongli Sun, Huifeng Li, Hanping Qi, Qianhui Zhang
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 4, p 437 (2016)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 4; Pages: 437
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 4; Pages: 437
(1) BACKGROUND: Transient receptor potential vanilloid 3 (TRPV3) is a member of the TRP channels family of Ca(2+)-permeant channels. The proteins of some TRP channels are highly expressed in cancer cells. This study aimed to assess the clinical signi
Autor:
Pierre Rivet, Celine Marquant, Claire Villalva, Michel Wager, Ulrich Cortes, Ali G. Turhan, Jean-Marc Tourani, Lucie Karayan-Tapon, Sébastien Martin
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 6, Pp 6983-6994 (2012)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 13; Issue 6; Pages: 6983-6994
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 13; Issue 6; Pages: 6983-6994
Glioblastoma (GBM) is the most malignant type of primary brain tumor with a very poor prognosis. The actual standard protocol of treatment for GBM patients consists of radiotherapy and concomitant temozolomide (TMZ). However, the therapeutic efficacy
Autor:
Hui-Rong Shi, Dong-Mei Fan
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 12, Pp 8489-8501 (2011)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 12; Issue 12; Pages: 8489-8501
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 12; Issue 12; Pages: 8489-8501
Background: Deletion in liver cancer gene (DLC1) and phosphorylated focal adhesion kinase (p-FAK) have recently been reported as metastasis-related genes. However, the roles and prognostic values of their expression in epithelial ovarian carcinomas (
Autor:
Barbara Ziegler, Sabine Zöchbauer-Müller, Gernot Kriegshäuser, Gerhild Fabjani, Robert Zeillinger, Adelheid End
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 12, Pp 8530-8538 (2011)
International Journal of Molecular Sciences
Volume 12
Issue 12
Pages 8530-8538
International Journal of Molecular Sciences
Volume 12
Issue 12
Pages 8530-8538
This study is aimed at evaluating the potential of a biochip assay to sensitively detect KRAS mutation in DNA from non-small cell lung cancer (NSCLC) tissue samples. The assay covers 10 mutations in codons 12 and 13 of the KRAS gene, and is based on
Autor:
Seiichiro Yoshizawa, Moritaka Gotoh, Junko H. Ohyashiki, Tomohiro Umezu, Chiaki Kobayashi, Kazuma Ohyashiki, Daigo Akahane, Yuu Saitoh
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2493 (2018)
Volume 19
Issue 9
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2493 (2018)
Volume 19
Issue 9
Recent studies have demonstrated that exosomal microRNAs (miRNAs) have the potential of facilitating molecular diagnosis. Currently, little is known about the underlying mechanism behind late-onset acute graft-versus-host disease (LA GVHD). Identifyi
Autor:
Gastone Castellani, Giuseppe Tarantino, M. A. Pantaleo, Annalisa Astolfi, Guido Biasco, Margaret von Mehren, Milena Urbini, Maristella Saponara, Michael Heinrich, Lidia Gatto, Giovanni Brandi, Michelangelo Fiorentino, Italo Faria do Valle, Margherita Nannini, Daniel Remondini, Janice Patterson, Valentina Indio, Donatella Santini
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 732 (2018)
International Journal of Molecular Sciences; Volume 19; Issue 3; Pages: 732
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 3; Pages: 732
International Journal of Molecular Sciences
Gastrointestinal stromal tumors (GIST) carrying the D842V activating mutation in the platelet-derived growth factor receptor alpha (PDGFRA) gene are a very rare subgroup of GIST (about 10%) known to be resistant to conventional tyrosine kinase inhibi
Autor:
Naoya Ishida, Chihiro Inoue, Yoshinori Okada, Hisafumi Yamada-Okabe, Yasuhiro Miki, Ryoko Saito, Hironobu Sasano, Masayuki Kobayashi, Shuko Hata
Publikováno v:
International Journal of Molecular Sciences; Volume 19; Issue 2; Pages: 609
International Journal of Molecular Sciences, Vol 19, Iss 2, p 609 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 2, p 609 (2018)
International Journal of Molecular Sciences
Epidermal growth factor receptor–tyrosine kinase inhibitor (EGFR-TKI) resistance is one of the most important problems in lung cancer therapy. Lung adenocarcinoma with EGFR-TKI resistance was reported to have higher abilities of invasion and migrat
Autor:
Rafal Pacholczyk, Kamran Mohammed, Jin-Xiong She, Dehuang Guo, Paul M. Weinberger, John A. Copland, Ashok Sharma, Paul Williams Biddinger, Sarabjot Singh Pabla, Qinqin Xu, Chien-Chung Chang, Kevin Friedrich, Robert C. Smallridge, John M. Koomen, Simarjot Pabla
Publikováno v:
International Journal of Molecular Sciences; Volume 19; Issue 2; Pages: 577
International Journal of Molecular Sciences, Vol 19, Iss 2, p 577 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 2, p 577 (2018)
International Journal of Molecular Sciences
Anaplastic thyroid carcinoma (ATC) is almost universally fatal. Elevated keratin-8 (KRT8) protein expression is an established diagnostic cancer biomarker in several epithelial cancers (but not ATC). Several keratins, including KRT8, have been sugges
Autor:
Laura Gonzalez Dos Anjos, Natália Galvão Garcia, Katia Candido Carvalho, Edmund Chada Baracat, Bruna Cristine de Almeida, Giovana De Nardo Maffazioli
Publikováno v:
International Journal of Molecular Sciences; Volume 19; Issue 1; Pages: 52
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International Journal of Molecular Sciences, Vol 19, Iss 1, p 52 (2017)
International Journal of Molecular Sciences
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International Journal of Molecular Sciences, Vol 19, Iss 1, p 52 (2017)
International Journal of Molecular Sciences
MicroRNAs (miRNAs) are small non-coding RNAs that act as regulators of gene expression at the post-transcriptional level. They play a key role in several biological processes. Their abnormal expression may lead to malignant cell transformation. This
Autor:
Stephen P. Pereira, Usha Menon, Harry J. Whitwell, John F. Timms, Marco Gaspari, Joy Cuenco, Aleksandra Gentry-Maharaj, Shibu Krishnan
Publikováno v:
International Journal of Molecular Sciences; Volume 18; Issue 12; Pages: 2670
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2670 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2670 (2017)
Biomarkers for the early detection of pancreatic cancer are urgently needed. The aim of this pilot study was to evaluate changes in serum N-glycoproteins and their glycosylation status prior to clinical presentation of pancreatic cancer that may be p