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Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12497, p 12497 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences
Volume 22
Issue 22
Hepatitis B virus (HBV) infection is closely related to hepatocellular carcinoma (HCC) development. To investigate the mechanism of HBV causing HCC, we previously analyzed the transcription of the HBV-transgenic cell line HepG2-4D14 and parental HepG
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12670, p 12670 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin, is known to play important roles in inhibiting proliferation rate, inducing apoptosis, as well as hindering the metastasis and invasion of glioma cells, but the underlying mechanis
Autor:
Giovanni Stallone, Michele Battaglia, Elena Ranieri, Margherita Gigante, Loreto Gesualdo, Federica Spadaccino, Giuseppe Stefano Netti, Maddalena Gigante, Marilisa Saldarelli, Giuseppe Castellano, Walter J. Storkus, Paola Pontrelli, Luigi Balducci
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8871, p 8871 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences
Volume 22
Issue 16
CD40 crosslinking plays an important role in regulating cell migration, adhesion and proliferation in renal cell carcinoma (RCC). CD40/CD40L interaction on RCC cells activates different intracellular pathways but the molecular mechanisms leading to c
Publikováno v:
Cells, Vol 10, Iss 1820, p 1820 (2021)
Cells
Volume 10
Issue 7
Cells
Volume 10
Issue 7
Background: Osteopontin (OPN) splice variants are identified as predictors of tumour progression and therapeutic resistance in certain types of solid tumours. However, their roles in gastric cancer (GC) remain poorly characterized. The current study
Autor:
Sanda Iacobas, Dumitru A. Iacobas
Publikováno v:
Cells, Vol 10, Iss 1644, p 1644 (2021)
Cells
Volume 10
Issue 7
Cells
Volume 10
Issue 7
Decades of research identified genomic similarities among prostate cancer patients and proposed general solutions for diagnostic and treatments. However, each human is a dynamic unique with never repeatable transcriptomic topology and no gene therapy
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5382, p 5382 (2021)
International journal of molecular sciences, vol 22, iss 10
International Journal of Molecular Sciences
Volume 22
Issue 10
International journal of molecular sciences, vol 22, iss 10
International Journal of Molecular Sciences
Volume 22
Issue 10
(1) Background: methionine cycle is not only essential for cancer cell proliferation but is also critical for metabolic reprogramming, a cancer hallmark. Hepatic and extrahepatic tissues methionine adenosyltransferases (MATs) are products of two gene
Autor:
Rafał Płoski, Małgorzata Rydzanicz, Tomasz M. Grzywa, Jarosław Wejman, Klaudia Klicka, Paweł Włodarski, Wiktor Paskal, Agnieszka Koppolu
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3886, p 3886 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 8
International Journal of Molecular Sciences
Volume 22
Issue 8
Melanoma tumors are the most heterogeneous of all tumor types. Tumor heterogeneity results in difficulties in diagnosis and is a frequent cause of failure in treatment. Novel techniques enable accurate examination of the tumor cells, considering thei
Autor:
Lam Nhat Nguyen, Xindi Dang, Zeyuan Lu, Yong Jiang, Madison Schank, Juan Zhao, Mohamed El Gazzar, Xiao Y. Wu, Jinyu Zhang, Ling Wang, Dechao Cao, Jonathan P. Moorman, Shunbin Ning, Zhi Q. Yao, Bal Krishna Chand Thakuri, Sushant Khanal, Lam Ngoc Thao Nguyen
Publikováno v:
Cells, Vol 9, Iss 2715, p 2715 (2020)
Cells
Volume 9
Issue 12
Cells
Volume 9
Issue 12
RUNX1 overlapping RNA (RUNXOR) is a long non-coding RNA and plays a pivotal role in the differentiation of myeloid cells via targeting runt-related transcription factor 1 (RUNX1). We and others have previously reported that myeloid-derived suppressor
Autor:
Gareth I. Owen, Tomas de Mayo, Enrique Norero, Franz Villarroel-Espindola, Maria Alejandra Alarcon, Alejandro H. Corvalan, Wilda Olivares, Julio D. Amigo, Gonzalo Carrasco-Avino, Marcelo Garrido, Miguel Cordova-Delgado, Natalia Landeros, Matías Muñoz-Medel, Ignacio A. Wichmann, Arnoldo Riquelme
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9472, p 9472 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences
Volume 21
Issue 24
Reprimo-like (RPRML) is an uncharacterized member of the Reprimo gene family. Here, we evaluated the role of RPRML and whether its regulation by DNA methylation is a potential non-invasive biomarker of gastric cancer. RPRML expression was evaluated b
Autor:
Takuya Mori, Yi Luo, Rina Fujiwara-Tani, Shiori Mori, Isao Kawahara, Kiyomu Fujii, Tadaaki Kirita, Shingo Kishi, Hiroki Kuniyasu, Kazuhiko Yamamoto, Chie Nakashima, Hitoshi Ohmori, Kei Goto, Takamitsu Sasaki
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7149, p 7149 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 19
International Journal of Molecular Sciences
Volume 21
Issue 19
Budding at the tumor invasive front has been correlated with the malignant properties of many cancers. Malic enzyme 1 (ME1) promotes the Warburg effect in cancer cells and induces epithelial&ndash
mesenchymal transition (EMT) in oral squamous ce
mesenchymal transition (EMT) in oral squamous ce