Zobrazeno 1 - 10
of 12
pro vyhledávání: ''
Autor:
Furdová A, Pooneh Chokhachi Baradaran, Bozena Smolkova, Lucia Demkova, Terezia Kurucova, Verona Buocikova, Andrea Soltysova, Dana Dvorská, Karin Jasek, Zuzana Dankova, Tatiana Sedlackova, Darina Lyskova, Gabriel Minarik, Pavel Babal, Viera Horvathova Kajabova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9651, p 9651 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Despite outstanding advances in diagnosis and the treatment of primary uveal melanoma (UM), nearly 50% of UM patients develop metastases via hematogenous dissemination, driven by the epithelial-mesenchymal transition (EMT). Despite the failure in UM
Autor:
Georges-Etienne Rivard, Christiane Auray-Blais, François Mercier, Iskren Menkovic, Michel Boutin, Abdulfatah Alayoubi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7869, p 7869 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences
Volume 21
Issue 21
Gaucher disease (GD) is a rare autosomal recessive multisystemic lysosomal storage disorder presenting a marked phenotypic and genotypic variability. GD is caused by a deficiency in the glucocerebrosidase enzyme. The diagnosis of GD remains challengi
Autor:
Paola Cafforio, Stella D'Oronzo, Loren Duda, Erica Silvestris, Raffaele Palmirotta, Angelo Paradiso, Gennaro Cormio, Domenica Lovero, Franco Silvestris
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6096, p 6096 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences
Volume 21
Issue 17
DEAD-Box Helicase 4 (Ddx4)+ ovarian stem cells are able to differentiate into several cell types under appropriate stimuli. Ddx4 expression has been correlated with poor prognosis of serous ovarian cancer (OC), while the potential role of Ddx4+ cells
Autor:
Susannah Hallal, Ali Azimi, Hao-Wen Sim, Nicholas Ho, Kimberley L. Kaufman, Maggie Lee, Heng Wei, Michael E. Buckland, Joanne Sy, Brindha Shivalingam
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4754, p 4754 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 13
International Journal of Molecular Sciences
Volume 21
Issue 13
Improving outcomes for diffuse glioma patients requires methods that can accurately and sensitively monitor tumour activity and treatment response. Extracellular vesicles (EV) are membranous nanoparticles that can traverse the blood&ndash
brain-
brain-
Autor:
Lina Zuccatosta, Martina Bonifazi, Monica Mattioli-Belmonte, Monia Orciani, Mariangela Di Vincenzo, Federico Mei, Stefano Gasparini, Michele Salati, Majed Refai, Miriam Caffarini
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8140, p 8140 (2020)
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8140, p 8140 (2020)
Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterized by fibroblasts activation, ECM accumulation, and diffused alveolar inflammation. The role of inflammation in IPF is still controversial and its involvement may follow nontradition
Autor:
Jielu Pan, Haiyan Song, Jiefeng Cui, Zemin Yao, Lei Wang, Yinkun Liu, Bing Hu, Hong-Zhu Wen, Guang Ji, Yang Liu
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 178-192 (2014)
International Journal of Molecular Sciences
Volume 16
Issue 1
Pages 178-192
International Journal of Molecular Sciences
Volume 16
Issue 1
Pages 178-192
The cAMP-regulated phosphoprotein 19 (ARPP-19) plays a key role in cell mitotic G2/M transition. Expression of ARPP-19 was increased in human hepatocellular carcinoma (HCC) compared to adjacent non-tumorous liver tissues in 36 paired liver samples, a
Autor:
Wenxiang Fang, Xiaoxiao Lu, Yifeng Zhou, Lei Yang, Fuman Qiu, Lan Zhang, Yinyan Li, Lisha Zhang, Jiachun Lu
Publikováno v:
International Journal of Molecular Sciences
Volume 15
Issue 10
Pages 17457-17468
International Journal of Molecular Sciences, Vol 15, Iss 10, Pp 17457-17468 (2014)
Volume 15
Issue 10
Pages 17457-17468
International Journal of Molecular Sciences, Vol 15, Iss 10, Pp 17457-17468 (2014)
Pregnane X receptor (PXR) is an important member of the nuclear receptor superfamily that copes with various endobiotic and xenobiotic stimuli, such as carcinogens by regulating an array of environmental response genes. Low PXR expression has been sh
Autor:
Hui-Rong Shi, Dong-Mei Fan
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 12, Pp 8489-8501 (2011)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 12; Issue 12; Pages: 8489-8501
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 12; Issue 12; Pages: 8489-8501
Background: Deletion in liver cancer gene (DLC1) and phosphorylated focal adhesion kinase (p-FAK) have recently been reported as metastasis-related genes. However, the roles and prognostic values of their expression in epithelial ovarian carcinomas (
Autor:
Barbara Ziegler, Sabine Zöchbauer-Müller, Gernot Kriegshäuser, Gerhild Fabjani, Robert Zeillinger, Adelheid End
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 12, Pp 8530-8538 (2011)
International Journal of Molecular Sciences
Volume 12
Issue 12
Pages 8530-8538
International Journal of Molecular Sciences
Volume 12
Issue 12
Pages 8530-8538
This study is aimed at evaluating the potential of a biochip assay to sensitively detect KRAS mutation in DNA from non-small cell lung cancer (NSCLC) tissue samples. The assay covers 10 mutations in codons 12 and 13 of the KRAS gene, and is based on
Autor:
Seiichiro Yoshizawa, Moritaka Gotoh, Junko H. Ohyashiki, Tomohiro Umezu, Chiaki Kobayashi, Kazuma Ohyashiki, Daigo Akahane, Yuu Saitoh
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2493 (2018)
Volume 19
Issue 9
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2493 (2018)
Volume 19
Issue 9
Recent studies have demonstrated that exosomal microRNAs (miRNAs) have the potential of facilitating molecular diagnosis. Currently, little is known about the underlying mechanism behind late-onset acute graft-versus-host disease (LA GVHD). Identifyi