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Publikováno v:
Cancers
Volume 15
Issue 5
Pages: 1446
Volume 15
Issue 5
Pages: 1446
Age as a breast cancer (BC) prognostic factor remains debatable. Several studies have investigated clinicopathological features at different ages, but few make an age group direct comparison. The European Society of Breast Cancer Specialists quality
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5382, p 5382 (2021)
International journal of molecular sciences, vol 22, iss 10
International Journal of Molecular Sciences
Volume 22
Issue 10
International journal of molecular sciences, vol 22, iss 10
International Journal of Molecular Sciences
Volume 22
Issue 10
(1) Background: methionine cycle is not only essential for cancer cell proliferation but is also critical for metabolic reprogramming, a cancer hallmark. Hepatic and extrahepatic tissues methionine adenosyltransferases (MATs) are products of two gene
Autor:
Udo Jeschke, Bastian Czogalla, Christina Kuhn, Martina Rahmeh, S Meister, Doris Mayr, Anna Hester, Tom Degenhardt, Sven Mahner, Anna Trebo, Nina Ditsch, Thomas Kolben, Elisa Schmoeckel
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2000, p 2000 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are involved in various immune cell-mediated diseases. Their role in cancer is poorly investigated, and research focusses on Siglec-expression on immune cells interacting with tumor cells. Thi
Autor:
Megan E. Tesch, Kara Laing
Publikováno v:
Current Oncology
Volume 26
Issue 3
Pages 4289-313
Volume 26
Issue 3
Pages 4289-313
Patients with metastatic cancer have a decreased life expectancy, and with screening and surveillance for new primary cancers, they run the risk of immediate harm with little chance of any benefit. Choosing Wisely Canada therefore recommends that suc
Autor:
Nobuhiko Sugito, Eriko Katsuta, Manabu Futamura, Nobuhisa Matsuhashi, Sumana Narayanan, Mariko Asaoka, Kazuaki Takabe, Yoshihisa Tokumaru, Masanori Oshi, Li Yan, Kazuhiro Yoshida, Yukihiro Akao
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3213, p 3213 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 9
International Journal of Molecular Sciences
Volume 21
Issue 9
microRNA-143(miR-143) is a well-known tumor suppressive microRNA that exhibits anti-tumoral function by targeting KRAS signaling pathways in various malignancies. We hypothesized that miR-143 suppresses breast cancer progression by targeting KRAS and
Autor:
Laura Pizzuti, Marina Pierdominici, Giada Pontecorvi, Paola Matarrese, Elisabetta Iessi, Maddalena Barba, Rossella Puglisi, Angela Maselli, Lucia Gabriele, Patrizia Vici, Stefania Parlato, Daniele Macchia, Carla Raggi, Massimo Spada, Francesca Cirulli, Elena Ortona, Maria Teresa Pagano, Alessandra Carè
Publikováno v:
Cells, Vol 8, Iss 7, p 750 (2019)
Cells
Cells
Tamoxifen resistance is a major hurdle in the treatment of estrogen receptor (ER)-positive breast cancer. The mechanisms of tamoxifen resistance are not fully understood although several underlying molecular events have been suggested. Recently, we i
Autor:
Jean-Louis Merlin, Maelle Chesnel, Charlène Thiébaut, Hélène Dumond, Alexandre Harlé, Agnès Leroux, Amand Chesnel
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2637 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2019, 20 (11), pp.2637. ⟨10.3390/ijms20112637⟩
Volume 20
Issue 11
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2019, 20 (11), pp.2637. ⟨10.3390/ijms20112637⟩
Volume 20
Issue 11
Breast cancer remains the major cause of cancer-induced morbidity and mortality in women. Among the different molecular subtypes, luminal tumors yet considered of good prognosis often develop acquired resistance to endocrine therapy. Recently, misreg
Autor:
Yoon Jin Cha, Ja Seung Koo
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2102 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 9
International Journal of Molecular Sciences
Volume 20
Issue 9
This research aimed to evaluate the expression and clinical implication of autotaxin (ATX)-lysophosphatidate (LPA) signaling-related proteins in breast cancer with adipose stroma. To this end, a tissue microarray (TMA) was constructed from 137 breast
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5453, p 5453 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 15
International Journal of Molecular Sciences
Volume 21
Issue 15
Phospholipase A2 receptor 1 (PLA2R1) expression and its role in the initiation and progression of breast cancer are an unresolved issue. PLA2R1 was found to endorse several tumor suppressive responses, including cellular senescence and apoptosis. Pre
Autor:
Igor Piotrowski, Joanna Wróblewska, Dawid Murawa, Wiktoria Maria Suchorska, Katarzyna Kulcenty, Karol Jopek, Marcin Rucinski
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1159 (2020)
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1159 (2020)
In patients with breast cancer who undergo breast-conserving surgery (BCS), more than 90% of local recurrences occur in the same quadrant as the primary cancer. Surgical wound fluids (SWF) are believed to play a role in this process by inducing an in