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Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12497, p 12497 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences
Volume 22
Issue 22
Hepatitis B virus (HBV) infection is closely related to hepatocellular carcinoma (HCC) development. To investigate the mechanism of HBV causing HCC, we previously analyzed the transcription of the HBV-transgenic cell line HepG2-4D14 and parental HepG
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12565, p 12565 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 22; Pages: 12565
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 22; Pages: 12565
International Journal of Molecular Sciences
Colony-stimulating factor 1 receptor (CSF-1R) acts as the receptor for colony stimulating factor 1, a cytokine that controls the production, differentiation, and function of macrophages. Prior studies showed cancer patients harboring germline CSF1R c
Autor:
Chiara Spadazzi, Laura Mercatali, Chiara Liverani, Lorena Gurrieri, Sebastiano Calpona, Anna Maria Ferrari, Giandomenico Di Menna, Federica Pieri, Chiara Domizio, Toni Ibrahim, Enrico Cavagna, Angelo Campobassi, Alessandro De Vita, Valentina Fausti, Nada Riva, Giovanni De Luca, Silvia Angela Debonis, Federica Recine, Anna Farnedi, Eugenia Franchini, Manlio Gessaroli, Claudia Cocchi, Giacomo Miserocchi, Silvia Vanni, Massimo Bassi, Alberto Bongiovanni
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11564, p 11564 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences
Volume 22
Issue 21
Adult rhabdomyosarcoma (RMS) represents an uncommon entity with an incidence of less than 3% of all soft tissue sarcomas (STS). Consequently, the natural history and the clinical management of this disease are infrequently reported. In order to fill
Autor:
Giovanni Stallone, Michele Battaglia, Elena Ranieri, Margherita Gigante, Loreto Gesualdo, Federica Spadaccino, Giuseppe Stefano Netti, Maddalena Gigante, Marilisa Saldarelli, Giuseppe Castellano, Walter J. Storkus, Paola Pontrelli, Luigi Balducci
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8871, p 8871 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences
Volume 22
Issue 16
CD40 crosslinking plays an important role in regulating cell migration, adhesion and proliferation in renal cell carcinoma (RCC). CD40/CD40L interaction on RCC cells activates different intracellular pathways but the molecular mechanisms leading to c
Autor:
Pavel Ivanov, Aldona Kasprzak, Mateusz Sowiński, Małgorzata Andrzejewska, Marta Leśniczak-Staszak, Paulina Pietras, Marcin Rucinski, Witold Szaflarski, Karol Jopek, Shawn M. Lyons
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12121, p 12121 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences
Volume 22
Issue 22
Cancer cells show significant dysregulation of genes expression, which may favor their survival in the tumor environment. In this study, the cellular vault’s components MVP (major vault protein), TEP1 (telomerase-associated protein 1) and vPARP (va
Autor:
Li Yun Hsu, Chao Hsuan Chen, Vijesh Kumar Yadav, Chi Tai Yeh, Narpati Wesa Pikatan, Shao Chih Chiu, Iat Hang Fong, Hao Yu Chuang, Chih Ming Pan
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10247, p 10247 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10247, p 10247 (2021)
Volume 22
Issue 19
Background: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. It is highly resistant to chemotherapy, and tumor recurrence is common. Neuronal precursor cell-expressed developmentally downregulated 4-1 (NEDD4-1) is an E3
Autor:
Claudia Scarponi, Cristina Albanesi, Sabatino Pallotta, Stefania Madonna, Martina Morelli, Laura Mercurio, Daniele Avitabile, Giovanni Luca Scaglione
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 13; Pages: 6860
International Journal of Molecular Sciences, Vol 22, Iss 6860, p 6860 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 13; Pages: 6860
International Journal of Molecular Sciences, Vol 22, Iss 6860, p 6860 (2021)
Dysregulated cross-talk between immune cells and epithelial compartments is responsible for the onset and amplification of pathogenic auto-inflammatory circuits occurring in psoriasis. NAMPT-mediated NAD salvage pathway has been recently described as
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 12
Int. J. Mol. Sci. 22:6502 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 6502, p 6502 (2021)
Volume 22
Issue 12
Int. J. Mol. Sci. 22:6502 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 6502, p 6502 (2021)
Several transmembrane mucins have demonstrated that they contribute intracellularly to induce fibrotic processes. The extracellular domain of MUC16 is considered as a biomarker for disease progression and death in IPF patients. However, there is no e