Zobrazeno 1 - 10
of 23
pro vyhledávání: ''
Autor:
Jürgen Weitz, Christopher Fabian Maier, Sebastian Schölch, Johannes Betge, Doreen William, Lahiri Kanth Nanduri, Daniel Kühn, May-Linn Thepkaysone, Christoph Reißfelder, Barbara Klink, Konrad Grützmann, Nuh N. Rahbari, Susan Kochall, Lei Zhu
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8675, p 8675 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences
Volume 22
Issue 16
Cholangiocarcinoma (CC) is an aggressive malignancy with an inferior prognosis due to limited systemic treatment options. As preclinical models such as CC cell lines are extremely rare, this manuscript reports a protocol of cholangiocarcinoma patient
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7731, p 7731 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences
Volume 21
Issue 20
Human dental pulp stem cells (DPSCs) have high clonogenic and proliferative potential. We previously reported that a helioxanthin derivative (4-(4-methoxyphenyl)pyrido[40,30:4,5]thieno[2&ndash
b]pyridine-2-carboxamide (TH)) enhances osteogenic d
b]pyridine-2-carboxamide (TH)) enhances osteogenic d
Autor:
Nobuhiko Sugito, Eriko Katsuta, Manabu Futamura, Nobuhisa Matsuhashi, Sumana Narayanan, Mariko Asaoka, Kazuaki Takabe, Yoshihisa Tokumaru, Masanori Oshi, Li Yan, Kazuhiro Yoshida, Yukihiro Akao
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3213, p 3213 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 9
International Journal of Molecular Sciences
Volume 21
Issue 9
microRNA-143(miR-143) is a well-known tumor suppressive microRNA that exhibits anti-tumoral function by targeting KRAS signaling pathways in various malignancies. We hypothesized that miR-143 suppresses breast cancer progression by targeting KRAS and
Autor:
Asako Doi, Hiroyuki Ariyasu, Hidefumi Inaba, Shinsuke Uraki, Hiroto Furuta, Takashi Akamizu, Shozo Yamada, Naoko Inoshita, Noriaki Fukuhara, Shuhei Morita, Ken Takeshima, Hiroshi Nishioka, Naoyuki Nakao
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2831, p 2831 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 8
International Journal of Molecular Sciences
Volume 21
Issue 8
Mismatch repair genes mutS homologs 6/2 (MSH6/2) expressions are involved in tumor growth and programmed cell death 1 ligand 1 (PD-L1) expression in tumor immunity, but the direct association with pituitary adenomas (PAs) is not well understood. We a
Autor:
Martin Clynes, Ray McDermott, Niall Swan, Justine Meiller, Neil T Conlon, Justin Geoghegan, Gerard McVey, Sandra Roche, Kevin C. Conlon, Ninfa L. Straubinger, Robert M. Straubinger, Michael Moriarty, Robert O'Connor, Jean Murphy, Rozana Abdul Rahman, Fiona O'Neill, Sinead Toomey
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 962 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 3
International Journal of Molecular Sciences
Volume 21
Issue 3
Pancreatic cancer remains among the most lethal cancers worldwide, with poor early detection rates and poor survival rates. Patient-derived xenograft (PDX) models have increasingly been used in preclinical and clinical research of solid cancers to fu
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5076 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 20
International Journal of Molecular Sciences
Volume 20
Issue 20
Thrombin is an essential procoagulant and profibrotic mediator. However, its implication in tuberculous pleural effusion (TBPE) remains unknown. The effusion thrombin and plasminogen activator inhibitor-1 (PAI-1) levels were measured among transudati
Autor:
Kazuhiro Tabata, Kohichi Kawahara, Masatatsu Yamamoto, Masaaki Komatsu, Toshiyuki Nagata, Tsubasa Hiraki, Kentaro Minami, Yukio Kato, Masashi Idogawa, Tatsuhiko Furukawa, Kazuhiro Ueda, Shun Kageyama, Masami Sato, Katsumi Fujimoto, Akihide Tanimoto, Ryuji Ikeda
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11509, p 11509 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences
Volume 22
Issue 21
Lung cancer constitutes a threat to human health. BHLHE41 plays important roles in circadian rhythm and cell differentiation as a negative regulatory transcription factor. This study investigates the role of BHLHE41 in lung cancer progression. We ana
Autor:
Li Yun Hsu, Chao Hsuan Chen, Vijesh Kumar Yadav, Chi Tai Yeh, Narpati Wesa Pikatan, Shao Chih Chiu, Iat Hang Fong, Hao Yu Chuang, Chih Ming Pan
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10247, p 10247 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10247, p 10247 (2021)
Volume 22
Issue 19
Background: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. It is highly resistant to chemotherapy, and tumor recurrence is common. Neuronal precursor cell-expressed developmentally downregulated 4-1 (NEDD4-1) is an E3
Autor:
Cody Howe, Yunna Lee, Charalabos Pothoulakis, Elise L. Ma, Marisa Patel, Sang Hoon Rhee, Yong Sung Kim, Gayoung Kim, Eunok Im
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1043, p 1043 (2021)
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1043, p 1043 (2021)
The neuroendocrine circuit of the corticotropin-releasing hormone (CRH) family peptides, via their cognate receptors CRHR1 and CRHR2, copes with psychological stress. However, peripheral effects of the CRH system in colon cancer remains elusive. Thus
Autor:
Eun-Wie Cho, Jong-Shin Yoo, Chang-Kyu Heo, Won-Hee Lim, Kook-Jin Lim, Hyejung Lee, Hai-Min Hwang
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9718, p 9718 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences
Volume 21
Issue 24
Tumor-associated (TA) autoantibodies have been identified at the early tumor stage before developing clinical symptoms, which holds hope for early cancer diagnosis. We identified a TA autoantibody from HBx-transgenic (HBx-tg) hepatocellular carcinoma