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Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 338, p 338 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
β-Endorphins are peptides that exert a wide variety of effects throughout the body. Produced through the cleavage pro-opiomelanocortin (POMC), β-endorphins are the primarily agonist of mu opioid receptors, which can be found throughout the body, br
Autor:
Felicita Pedata, Federica Cherchi, Kenneth A. Jacobson, Carla Ghelardini, Daniela Salvemini, Elisabetta Coppi, Anna Maria Pugliese, Lorenzo Di Cesare Mannelli, Elena Lucarini
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7952, p 7952 (2021)
Agonists of the Gi protein-coupled A3 adenosine receptor (A3AR) have shown important pain-relieving properties in preclinical settings of several pain models. Active as a monotherapy against chronic pain, A3AR agonists can also be used in combination
Publikováno v:
Molecules, Vol 26, Iss 4598, p 4598 (2021)
MOLECULES
Molecules
Volume 26
Issue 15
MOLECULES
Molecules
Volume 26
Issue 15
Cefquinome and ceftiofur are β-lactam antibiotics used for the treatment of bacterial infections in swine. Although these antimicrobials are administered intramuscularly, the exposure of the gut microbiota to these cephalosporins is not well describ
Autor:
Grace N Jang, M. Bruce MacIver
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8091, p 8091 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences
Volume 22
Issue 15
Ketamine is a clinical anesthetic and antidepressant. Although ketamine is a known NMDA receptor antagonist, the mechanisms contributing to antidepression are unclear. This present study examined the loci and duration of ketamine’s actions, and the
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7731, p 7731 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Retinoic acid (RA) agents possess anti-tumor activity through their ability to induce cellular differentiation. However, retinoids have not yet been translated into effective systemic treatments for most solid tumors. RA signaling is mediated by the
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6654, p 6654 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences
Volume 22
Issue 13
The ‘shock-and-kill’ strategy to purge the latent HIV reservoir relies on latency-reversing agents (LRAs) to reactivate the provirus and subsequent immune-mediated killing of HIV-expressing cells. Yet, clinical trials employing histone deacetylas
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5617, p 5617 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11
Vestergaard, M, Skive, B, Domraceva, I, Ingmer, H & Franzyk, H 2021, ' Peptide/β-Peptoid Hybrids with Activity against Vancomycin-Resistant Enterococci : Influence of Hydrophobicity and Structural Features on Antibacterial and Hemolytic Properties ', International Journal of Molecular Sciences, vol. 22, no. 11, 5617 . https://doi.org/10.3390/ijms22115617
International Journal of Molecular Sciences
Volume 22
Issue 11
Vestergaard, M, Skive, B, Domraceva, I, Ingmer, H & Franzyk, H 2021, ' Peptide/β-Peptoid Hybrids with Activity against Vancomycin-Resistant Enterococci : Influence of Hydrophobicity and Structural Features on Antibacterial and Hemolytic Properties ', International Journal of Molecular Sciences, vol. 22, no. 11, 5617 . https://doi.org/10.3390/ijms22115617
Infections with enterococci are challenging to treat due to intrinsic resistance to several antibiotics. Especially vancomycin-resistant Enterococcus faecium and Enterococcus faecalis are of considerable concern with a limited number of efficacious t
Autor:
Gildardo Rivera, Isidro Palos, Elizabeth Barbosa-Cabrera, Virgilio Bocanegra-García, Nuria E. Campillo, Alfredo Juárez-Saldivar, Ana Verónica Martínez-Vázquez, Alma D Paz-González, Edgar E. Lara-Ramírez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5943, p 5943 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences
Volume 22
Issue 11
Digital.CSIC. Repositorio Institucional del CSIC
instname
8 p.-3 fig.-1 tab.
Infectious diseases caused by intestinal protozoan, such as Entamoeba histolytica (E. histolytica) and Giardia lamblia (G. lamblia) are a worldwide public health issue. They affect more than 70 million people every year. They
Infectious diseases caused by intestinal protozoan, such as Entamoeba histolytica (E. histolytica) and Giardia lamblia (G. lamblia) are a worldwide public health issue. They affect more than 70 million people every year. They
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4013, p 4013 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Xenoestrogens (XEs) are substances that imitate endogenous estrogens to affect the physiologic functions of humans or other animals. As endocrine disruptors, they can be either synthetic or natural chemical compounds derived from diet, pesticides, co
Autor:
Mio Yamane, Kazuo Tsubota, Shinji Fukuda, Kazuki Asai, Eisuke Shimizu, Hiroyuki Yazu, Fan Yang, Mamoru Ogawa, Yoko Ogawa, Yutaka Kawakami, Jingliang He, Robert Maximilian Rusch, Shinri Sato
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3745, p 3745 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences
Volume 22
Issue 7
Chronic graft-versus-host disease (cGVHD) is one of the most frequent complications experienced after allogeneic hematopoietic stem cell transplantation. Reportedly, dysbiosis and severe damage to the microbiome are also closely associated with GVHD.