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Autor:
Brandon J. Henderson, Skylar Y. Cooper
Publikováno v:
Molecules, Vol 25, Iss 4223, p 4223 (2020)
Molecules
Molecules
Over the past two decades, combustible cigarette smoking has slowly declined by nearly 11% in America; however, the use of electronic cigarettes has increased tremendously, including among adolescents. While nicotine is the main addictive component o
Publikováno v:
Molecules, Vol 25, Iss 1, p 211 (2020)
Molecules, vol. 25, no. 1, 211, 2020.
Molecules
Volume 25
Issue 1
Molecules, vol. 25, no. 1, 211, 2020.
Molecules
Volume 25
Issue 1
Mammalian paraoxonase-1 hydrolyses a very broad spectrum of esters such as certain drugs and xenobiotics. The aim of this study was to determine whether carbamates influence the activity of recombinant PON1 (rePON1). Carbamates were selected having a
Publikováno v:
Molecules, Vol 25, Iss 2, p 247 (2020)
Molecules
Volume 25
Issue 2
Molecules
Volume 25
Issue 2
Multidrug resistance (MDR) is a complicated ever-changing problem in cancer treatment, and P-glycoprotein (P-gp), a drug efflux pump, is regarded as the major cause. In the way of developing P-gp inhibitors, natural products such as phenolic acids ha
Publikováno v:
Molecules, Vol 24, Iss 14, p 2596 (2019)
Molecules
Volume 24
Issue 14
Molecules
Volume 24
Issue 14
Psoriasis is an immune-mediated inflammatory dermatosis characterized by epidermal hyperplasia and excessive infiltration of inflammatory cells. Withanolides, extracted from Datura metel L.
are the main effective components for the treatment of
are the main effective components for the treatment of
Publikováno v:
Molecules, Vol 23, Iss 12, p 3305 (2018)
N-acetylcysteine (NAC), which is an acetylated cysteine compound, has aroused scientific interest for decades due to its important medical applications. It also represents a nutritional supplement in the human diet. NAC is a glutathione precursor and
Publikováno v:
Molecules, Vol 23, Iss 12, p 3267 (2018)
Molecules
Volume 23
Issue 12
Molecules
Volume 23
Issue 12
WOS: 000454523000217
PubMed ID: 30544766
Cisplatin is one of the most active cytotoxic agents in cancer treatment. To clarify the interaction with mitochondria, we hypothesize that the activities of mitochondrial electron transport chain (E
PubMed ID: 30544766
Cisplatin is one of the most active cytotoxic agents in cancer treatment. To clarify the interaction with mitochondria, we hypothesize that the activities of mitochondrial electron transport chain (E
Publikováno v:
Molecules, Vol 24, Iss 1, p 131 (2018)
Molecules
Volume 24
Issue 1
Molecules
Volume 24
Issue 1
Baicalein (BAI), one of the main components of Scutellaria baicalensis Georgi, possesses numerous pharmacological properties, including anti-cancer, anti-oxidative, anti-virus and anti-bacterial activities. The purpose of this study was to evaluate t
Cholinergic Agonists and Antagonists Have an Effect on the Metabolism of the Beetle Tenebrio Molitor
Publikováno v:
Molecules, Vol 24, Iss 1, p 17 (2018)
Molecules
Volume 24
Issue 1
Molecules
Volume 24
Issue 1
Synthetic insecticides are still widely used in plant protection. The main target for their action is the nervous system, in which the cholinergic system plays a vital role. Currently available insecticides have low selectivity and act on the choline
Autor:
Sheila Leone, Lidia Leporini, Adriano Mollica, Luigi Menghini, Azzurra Stefanucci, Lucia Recinella, Claudio Ferrante, Marilisa Pia Dimmito, Giustino Orlando, Annalisa Chiavaroli, Luigi Brunetti, Giorgia Macedonio
Publikováno v:
Molecules, Vol 23, Iss 12, p 3071 (2018)
Molecules
Volume 23
Issue 12
Molecules
Volume 23
Issue 12
Besides its role as key regulator in gonadotropin releasing hormone secretion, reproductive function, and puberty onset, kisspeptin has been proposed to act as a bridge between energy homeostasis and reproduction. In the present study, to characteriz
Autor:
Thomas C. Chen, Francis S. Markland, Cao Duc Tuan, Thu-Zan Thein, Radu O. Minea, Steve Swenson
Publikováno v:
Molecules, Vol 23, Iss 11, p 2918 (2018)
Molecules
Volume 23
Issue 11
Molecules
Volume 23
Issue 11
We developed a bacterial expression system to produce a recombinant disintegrin, vicrostatin (VCN), whose structure is based on a natural disintegrin isolated from southern copperhead snake venom. Our goal is to develop VCN for potential clinical tra