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Autor:
Annalisa Cossu, Duong Thi Bich Thuan, Gianfranco Pintus, Anna Maria Posadino, Roberta Giordo, Angelo Zinellu, Gian Luca Erre
Publikováno v:
Molecules, Vol 26, Iss 4729, p 4729 (2021)
Molecules
Molecules
Endothelial cell injury is an early event in systemic sclerosis (SSc) pathogenesis and several studies indicate oxidative stress as the trigger of SSc-associated vasculopathy. Here, we show that circulating factors present in sera of SSc patients inc
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7742, p 7742 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 14; Pages: 7742
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 14; Pages: 7742
International Journal of Molecular Sciences
A real-life environment during pregnancy involves multiple and simultaneous exposures to toxic chemicals. Perinatal exposures to toxic chemicals have been reported to exert an inhibitory effect on mouse neural development and behaviors. However, the
Publikováno v:
Nutrients, Vol 13, Iss 2258, p 2258 (2021)
Nutrients
Volume 13
Issue 7
Nutrients
Volume 13
Issue 7
Ventilator-induced lung injury (VILI) is an important critical care complication. Nuclear factor-κB (NF-κB) activation, a critical signaling event in the inflammatory response, has been implicated in the tracking of the lung injury. The present stu
Autor:
Khaldoun S. Abdelwahed, Jafrin Jobayer Sonju, Mohammed H. Qusa, Abu Bakar Siddique, Khalid A. El Sayed, Afsana Tajmim, Judy A. King, Areli K Cuevas-Ocampo
Publikováno v:
Nutrients, Vol 13, Iss 1702, p 1702 (2021)
Nutrients
Volume 13
Issue 5
Nutrients
Volume 13
Issue 5
Alzheimer’s disease (AD) is a complex progressive neurodegenerative disorder affecting humans mainly through the deposition of Aβ-amyloid (Aβ) fibrils and accumulation of neurofibrillary tangles in the brain. Currently available AD treatments onl
Autor:
Annina S. Vischer, Thilo Burkard, Stefan Osswald, Otmar Pfister, Qian Zhou, Raphael Twerenbold, Stephan Krähenbühl, Michael Mayr, Andrea Villiger, Manuel Haschke, Marko Poglitsch, Gabriela M. Kuster
Publikováno v:
Cells, Vol 10, Iss 534, p 534 (2021)
Cells
Volume 10
Issue 3
Vischer, Annina S; Kuster, Gabriela M; Twerenbold, Raphael; Pfister, Otmar; Zhou, Qian; Villiger, Andrea; Poglitsch, Marko; Krähenbühl, Stephan; Mayr, Michael; Osswald, Stefan; Haschke, Manuel; Burkard, Thilo (2021). Influence of Antihypertensive Treatment on RAAS Peptides in Newly Diagnosed Hypertensive Patients. Cells, 10(3) MDPI 10.3390/cells10030534
Publons
Cells
Volume 10
Issue 3
Vischer, Annina S; Kuster, Gabriela M; Twerenbold, Raphael; Pfister, Otmar; Zhou, Qian; Villiger, Andrea; Poglitsch, Marko; Krähenbühl, Stephan; Mayr, Michael; Osswald, Stefan; Haschke, Manuel; Burkard, Thilo (2021). Influence of Antihypertensive Treatment on RAAS Peptides in Newly Diagnosed Hypertensive Patients. Cells, 10(3) MDPI 10.3390/cells10030534
Publons
(1) Background: Recently, influences of antihypertensive treatment on the renin–angiotensin–aldosterone system (RAAS) has gained attention, regarding a possible influence on inflammatory and anti-inflammatory pathways. We aimed to study the effec
Autor:
Ilona Jaspers, Yi-Hsuan Tsai, Marielle C. Brinkman, Samera H. Hamad, Courtney A. Granville, Kandice S Cross, Pamela I. Clark, Namya Mellouk
Publikováno v:
Genes, Vol 12, Iss 448, p 448 (2021)
Genes
Volume 12
Issue 3
Genes
Volume 12
Issue 3
There is a paucity of data on how gene expression enables identification of individuals who are at risk of exposure to carcinogens from e-cigarette (e-cig) vaping
and how human vaping behaviors modify these exposures. This pilot study aimed to i
and how human vaping behaviors modify these exposures. This pilot study aimed to i
Autor:
Hydar Ali, Aetas Amponnawarat, Saptarshi Roy, Chalatip Chompunud Na Ayudhya, Carole A. Oskeritzian
Publikováno v:
Cells, Vol 10, Iss 156, p 156 (2021)
Cells
Cells
Perioperative hypersensitivity (POH) to the neuromuscular blocking drug (NMBD) rocuronium was previously thought to be IgE and mast cell (MC)-mediated. However, the recent seminal observation that rocuronium induces degranulation in murine peritoneal
Publikováno v:
Biomolecules, Vol 10, Iss 1364, p 1364 (2020)
Biomolecules
Volume 10
Issue 10
Biomolecules
Volume 10
Issue 10
Autism spectrum disorders (ASDs) comprise a genetically heterogeneous group of conditions characterized by a multifaceted range of impairments and multifactorial etiology. Epidemiological studies have identified valproic acid (VPA), an anticonvulsant
Autor:
Giselli Scaini, Omar F. Pinjari, Gabriela D. Colpo, Antônio Lúcio Teixeira, João Quevedo, Tejaswini Doifode, Danielle Silveira Macêdo, Tatiana Barichello, Fabricia Petronilho, Vijayasree V. Giridharan
Publikováno v:
Cells, Vol 9, Iss 3, p 577 (2020)
Cells
Volume 9
Issue 3
Cells
Volume 9
Issue 3
Schizophrenia is a complex psychiatric disorder that exhibits an interconnection between the immune system and the brain. Experimental and clinical studies have suggested the presence of neuroinflammation in schizophrenia. In the present study, the e
Autor:
Jóhannes Reynisson, Raina Chand, Daniel M Ayine-Tora, Valeriy P. Nikolin, Olga D. Zakharova, Ekaterina S Ilina, Dina V. Korchagina, Olga I. Lavrik, Jinal Patel, Alexandra L. Zakharenko, N.F. Salakhutdinov, Arina A Chepanova, V. I. Kaledin, T. M. Khomenko, Konstantin P. Volcho, Ivanhoe K. H. Leung, Nelly A Popova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 126 (2019)
International Journal of Molecular Sciences; Volume 21; Issue 1; Pages: 126
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 21; Issue 1; Pages: 126
International Journal of Molecular Sciences
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is an important DNA repair enzyme in humans, and a current and promising inhibition target for the development of new chemosensitizing agents due to its ability to remove DNA damage caused by topoisomerase 1 (To