Zobrazeno 1 - 10
of 51
pro vyhledávání: ''
Autor:
Anna Pawłowska, Bartłomiej Barczyński, Iwona Wertel, Agnieszka Kwiatkowska, Rafał Tarkowski, Dorota Suszczyk, Jan Kotarski, Agata Chudzik
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11563, p 11563 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11563, p 11563 (2021)
The latest literature demonstrates the predominant role of the programmed cell death axis (PD-1/PD-L1/PD-L2) in ovarian cancer (OC) pathogenesis. However, data concerning this issue is ambiguous. Our research aimed to evaluate the clinical importance
Autor:
Fleur van der Sijde, Marjolein Y. V. Homs, Marlies L. van Bekkum, Thierry P. P. van den Bosch, Koop Bosscha, Marc G. Besselink, Bert A. Bonsing, Jan Willem B. de Groot, Thomas M. Karsten, Bas Groot Koerkamp, Brigitte C. M. Haberkorn, Saskia A. C. Luelmo, Leonie J. M. Mekenkamp, Dana A. M. Mustafa, Johanna W. Wilmink, Casper H. J. van Eijck, Eveline E. Vietsch, on behalf of the Dutch Pancreatic Cancer Group
Publikováno v:
International Journal of Molecular Sciences
International journal of molecular sciences, 22(20):10902. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 22, Iss 10902, p 10902 (2021)
Volume 22
Issue 20
International Journal of Molecular Sciences, 22(20). MDPI
International Journal of Molecular Sciences, 22(20):10902. Multidisciplinary Digital Publishing Institute (MDPI)
International journal of molecular sciences, 22(20):10902. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 22, Iss 10902, p 10902 (2021)
Volume 22
Issue 20
International Journal of Molecular Sciences, 22(20). MDPI
International Journal of Molecular Sciences, 22(20):10902. Multidisciplinary Digital Publishing Institute (MDPI)
In this study, we explored the predictive value of serum microRNA (miRNA) expression for early tumor progression during FOLFIRINOX chemotherapy and its association with overall survival (OS) in patients with pancreatic ductal adenocarcinoma (PDAC). A
Autor:
José-Alain Sahel, Saddek Mohand-Said, Isabelle Audo, Crystel Bonnet, Eberhart Zrenner, Marko Hawlina, Anne Kurtenbach, Francesca Simonelli, Ditta Zobor, Christine Petit, Katarina Stingl, Francesco Testa, Ana Fakin
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 22 (19), pp.10352. ⟨10.3390/ijms221910352⟩
Volume 22
Issue 19
International Journal of Molecular Sciences, MDPI, 2021, 22 (19), pp.10352. ⟨10.3390/ijms221910352⟩
International Journal of Molecular Sciences, Vol 22, Iss 10352, p 10352 (2021)
International Journal of Molecular Sciences, 2021, 22 (19), pp.10352. ⟨10.3390/ijms221910352⟩
Volume 22
Issue 19
International Journal of Molecular Sciences, MDPI, 2021, 22 (19), pp.10352. ⟨10.3390/ijms221910352⟩
International Journal of Molecular Sciences, Vol 22, Iss 10352, p 10352 (2021)
In contrast to USH2A, variants in ADGRV1 are a minor cause of Usher syndrome type 2, and the associated phenotype is less known. The purpose of the study was to characterize the retinal phenotype of 18 ADGRV1 patients (9 male, 9 female
median ag
median ag
Autor:
Sardar Sindhu, Ashraf Al-Madhoun, Hossein Arefanian, Reeby Thomas, Fahd Al-Mulla, Shihab Kochumon, Ajit Wilson, Fatema Al-Rashed, Rasheed Ahmad, Areej Al-Roub, Nadeem Akhter
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10519, p 10519 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10519, p 10519 (2021)
Volume 22
Issue 19
IL-8/MCP-1 act as neutrophil/monocyte chemoattractants, respectively. Oxidative stress emerges as a key player in the pathophysiology of obesity. However, it remains unclear whether the TNF-α/oxidative stress interplay can trigger IL-8/MCP-1 express
Autor:
Karolina Akinosoglou, Ioanna Dimopoulou, Maria Evangelidou, Vasiliki Dimakopoulou, Emmanouil Angelakis, Dionysios Fanidis, George Mpekoulis, Niki Vassilaki, Ioanna Nikitopoulou, Panagiotis Moulos, Argyris Tzouvelekis, Stylianos E. Orfanos, Konstantinos Ntatsoulis, Edison Jahaj, Vassilis Aidinis, Anastasia Kotanidou, Stamatios Tsipilis, Alice G. Vassiliou
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 10006, p 10006 (2021)
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 10006, p 10006 (2021)
Autotaxin (ATX
ENPP2) is a secreted lysophospholipase D catalyzing the extracellular production of lysophosphatidic acid (LPA), a pleiotropic signaling phospholipid. Genetic and pharmacologic studies have previously established a pathologic role
ENPP2) is a secreted lysophospholipase D catalyzing the extracellular production of lysophosphatidic acid (LPA), a pleiotropic signaling phospholipid. Genetic and pharmacologic studies have previously established a pathologic role
Autor:
Alino Martinez-Marcos, Melania Gonzalez-Rodriguez, Alicia Flores-Cuadrado, Sandra Villar-Conde, Daniel Saiz-Sanchez, Patricia Villanueva-Anguita, Isabel Ubeda-Bañon, Veronica Astillero-Lopez, M Eugenia Paya-Rodriguez
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8434, p 8434 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8434, p 8434 (2021)
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease in the elderly. Progressive accumulation of insoluble isoforms of amyloid-β peptide (Aβ) and tau protein are the major neuropathologic hallmarks, and the loss of cholinergic
Autor:
Takamichi Ito, Yuka Tanaka, Maho Murata, Keiko Tanegashima, Yumiko Kaku-Ito, Yoshinao Oda, Hiroki Hashimoto
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7706, p 7706 (2021)
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7706, p 7706 (2021)
Extramammary Paget’s disease (EMPD) is a rare skin cancer arising in the apocrine gland-rich areas. Most EMPD tumors are dormant, but metastatic lesions are associated with poor outcomes owing to the lack of effective systemic therapies. Trophoblas
Autor:
Feliksas Jankevičius, Juozas R. Lazutka, Kristina Daniunaite, Arnas Bakavicius, Kristina Zukauskaite, Albertas Ulys, Sonata Jarmalaite, Ieva Rauluseviciute
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6091, p 6091 (2021)
International journal of molecular sciences, Basel : MDPI, 2021, vol. 22, iss. 11, art. no. 6091, p. [1-13]
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 6091, p 6091 (2021)
International journal of molecular sciences, Basel : MDPI, 2021, vol. 22, iss. 11, art. no. 6091, p. [1-13]
Volume 22
Issue 11
The molecular diversity of prostate cancer (PCa) has been demonstrated by recent genome-wide studies, proposing a significant number of different molecular markers. However, only a few of them have been transferred into clinical practice so far. The
Autor:
Diane Provencher, Maxime Cahuzac, Martin Köbel, Laudine Communal, Kurosh Rahimi, Noémi Roy, Anne-Marie Mes-Masson
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5325, p 5325 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5325, p 5325 (2021)
During tubo-ovarian high-grade serous carcinoma (HGSC) progression, tumoral cells undergo phenotypic changes in their epithelial marker profiles, which are essential for dissemination processes. Here, we set out to determine whether standard epitheli
Autor:
Gaowa Bai, Toshiro Niki, Yugo Ashino, Takashi Matsuba, Toshio Hattori, Atsushi Takahashi, Daisuke Furushima, Yosuke Maeda
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 4978, p 4978 (2021)
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4978, p 4978 (2021)
Volume 22
Issue 9
Numbers of patients with coronavirus disease 2019 (COVID-19) have increased rapidly worldwide. Plasma levels of full-length galectin-9 (FL-Gal9) and osteopontin (FL-OPN) as well as their truncated forms (Tr-Gal9, Ud-OPN, respectively), are representa