Zobrazeno 1 - 10
of 73
pro vyhledávání: ''
Autor:
Anne Chew, David M. Barrett, Yolanda D. Mahnke, Bruce L. Levine, Noelle Frey, David L. Porter, Pamela A. Shaw, J. Joseph Melenhorst, Carl H. June, Zhaohui Zheng, Susan R. Rheingold, Nancy Bunin, Shannon L. Maude, Vanessa E. Gonzalez, David T. Teachey, Stephan A. Grupp, Simon F. Lacey, Angela Shen, Richard Aplenc
Publikováno v:
New England Journal of Medicine. 371:1507-1517
Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies. Chimeric antigen receptor-modified T cells targeting CD19 may overcome many limitations of conventional therapies and induce remission
Autor:
Adjoa A Bucknor, Peter J. Allen, Ronald P. DeMatteo, Yuman Fong, Michael I. D’Angelica, T. Peter Kingham, Murray F. Brennan, Kate E Carlucci, William R. Jarnagin, Lindsay M Robinson, Marisa M Pappas, Mithat Gonen
Publikováno v:
New England Journal of Medicine. 370:2014-2022
Postoperative pancreatic fistula is a major contributor to complications and death associated with pancreatic resection. Pasireotide, a somatostatin analogue that has a longer half-life than octreotide and a broader binding profile, decreases pancrea
Publikováno v:
New England Journal of Medicine. 366:1010-1019
Actinic keratosis is a common precursor to sun-related squamous-cell carcinoma. Treating actinic keratoses and the surrounding skin area (i.e., field therapy) can eradicate clinical and subclinical actinic keratoses. Topical field therapy currently r
Autor:
Aurelius Omlin, Desamparados Roda, Syed A. Hussain, Ursula McGovern, Gerhardt Attard, Gunther Boysen, Helen Pemberton, Karen E. Knudsen, Raquel Perez-Lopez, Wei Yuan, Johann S. de Bono, Suzanne Carreira, Yi-Mi Wu, Susana Miranda, Amanda Swain, Diletta Bianchini, Daniel Nava Rodrigues, Roger A'Hern, Rosalind A. Eeles, Felix Y. Feng, Roberta Ferraldeschi, Rachel Brough, Ruth Riisnaes, Shahneen Sandhu, Dan R. Robinson, Lakshmi P. Kunju, Alan Ashworth, Zafeiris Zafeiriou, Christy Ralph, Andrew Protheroe, Xuhong Cao, Joaquin Mateo, Mark A. Rubin, Emma Hall, Ines Figueiredo, Chris T. Williamson, Nuria Porta, Tony Elliott, Helen Mossop, George Seed, Jane C. Goodall, Claire Paulding, Alexa Gillman, Nina Tunariu, Suneil Jain, Arul M. Chinnaiyan, Penny Flohr, Christopher J. Lord, Bernardette Ebbs, Gemma Fowler, Robert Jones
Publikováno v:
The New England journal of medicine, vol 373, iss 18
European Urology, 70, 204-5
European Urology, 70, 1, pp. 204-5
NEW ENGLAND JOURNAL OF MEDICINE
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Mateo, J, Carreira, S, Sandhu, S, Miranda, S, Mossop, H, Perez-Lopez, R, Nava Rodrigues, D, Robinson, D, Omlin, A, Tunariu, N, Boysen, G, Porta, N, Flohr, P, Gillman, A, Figueiredo, I, Paulding, C, Seed, G, Jain, S, Ralph, C, Protheroe, A, Hussain, S, Jones, R, Elliott, T, McGovern, U, Bianchini, D, Goodall, J, Zafeiriou, Z, Williamson, C T, Ferraldeschi, R, Riisnaes, R, Ebbs, B, Fowler, G, Roda, D, Yuan, W, Wu, Y-M, Cao, X, Brough, R, Pemberton, H, A'Hern, R, Swain, A, Kunju, L P, Eeles, R, Attard, G, Lord, C J, Ashworth, A, Rubin, M A, Knudsen, K E, Feng, F Y, Chinnaiyan, A M, Hall, E & de Bono, J S 2015, ' DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer ', New England Journal of Medicine, vol. 373, no. 18, pp. 1697-1708 . https://doi.org/10.1056/NEJMoa1506859
European Urology, 70, 204-5
European Urology, 70, 1, pp. 204-5
NEW ENGLAND JOURNAL OF MEDICINE
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Mateo, J, Carreira, S, Sandhu, S, Miranda, S, Mossop, H, Perez-Lopez, R, Nava Rodrigues, D, Robinson, D, Omlin, A, Tunariu, N, Boysen, G, Porta, N, Flohr, P, Gillman, A, Figueiredo, I, Paulding, C, Seed, G, Jain, S, Ralph, C, Protheroe, A, Hussain, S, Jones, R, Elliott, T, McGovern, U, Bianchini, D, Goodall, J, Zafeiriou, Z, Williamson, C T, Ferraldeschi, R, Riisnaes, R, Ebbs, B, Fowler, G, Roda, D, Yuan, W, Wu, Y-M, Cao, X, Brough, R, Pemberton, H, A'Hern, R, Swain, A, Kunju, L P, Eeles, R, Attard, G, Lord, C J, Ashworth, A, Rubin, M A, Knudsen, K E, Feng, F Y, Chinnaiyan, A M, Hall, E & de Bono, J S 2015, ' DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer ', New England Journal of Medicine, vol. 373, no. 18, pp. 1697-1708 . https://doi.org/10.1056/NEJMoa1506859
BACKGROUND Prostate cancer is a heterogeneous disease, but current treatments are not based on molecular stratification. We hypothesized that metastatic, castration-resistant prostate cancers with DNA-repair defects would respond to poly(adenosine di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97eeacfb2359617edb38c47804d7bc6f
https://eprints.whiterose.ac.uk/94266/1/nejmoa1506859.pdf
https://eprints.whiterose.ac.uk/94266/1/nejmoa1506859.pdf
Autor:
Hans-Peter Gerber, J. Ashley Jefferson, Vera Eremina, Susan E. Quaggin, Napoleone Ferrara, Joseph Weisstuch, Charles E. Alpers, Catherine A. Richardson, Jeffrey B. Kopp, Peter H. Backx, Mark Haas, Jolanta Kowalewska, M. Golam Kabir, Howard S. Hochster, Laura Barisoni
Publikováno v:
New England Journal of Medicine. 358:1129-1136
The glomerular microvasculature is particularly susceptible to injury in thrombotic microangiopathy, but the mechanisms by which this occurs are unclear. We report the cases of six patients who were treated with bevacizumab, a humanized monoclonal an
Autor:
Dan L. Stewart, David J. Durand, Richard J. Martin, Avital Cnaan, Mark L. Hudak, Roberta A. Ballard, Dennis E. Mayock, Philip L. Ballard, Sandra R. Wadlinger, Eric C. Eichenwald, Asha R. Puri, Jeffrey D. Merrill, Sergio G. Golombek, Stephen E. Welty, Michele C. Walsh, Anna Maria Hibbs, Roderic H. Phibbs, Donald R. Null, William E Truog, Jeanette M. Asselin, Christine E. Coburn, Sherry E. Courtney, Xianqun Luan
Publikováno v:
New England Journal of Medicine. 355:343-353
Bronchopulmonary dysplasia in premature infants is associated with prolonged hospitalization, as well as abnormal pulmonary and neurodevelopmental outcome. In animal models, inhaled nitric oxide improves both gas exchange and lung structural developm
Autor:
Federica Bevilacqua, Michele Maria Luchetti, Tatiana Spadoni, Paolo Fraticelli, Armando Gabrielli, Mariarosaria Santillo, Silvia Baroni, Andrius Kazlauskas, Ada Funaro, Enrico V. Avvedimento, Paola Sambo, Matteo Mancini
Publikováno v:
New England Journal of Medicine. 354:2667-2676
Systemic sclerosis (scleroderma) is characterized by immunologic abnormalities, injury of endothelial cells, and tissue fibrosis. Abnormal oxidative stress has been documented in scleroderma and linked to fibroblast activation. Since platelet-derived
Autor:
Preben G. Berthelsen, Paul E. Marik
Publikováno v:
New England Journal of Medicine. 373:2686-2687
To the Editor: In the July 30 issue of the Journal, Niemann and colleagues published their investigation on therapeutic hypothermia in deceased organ donors and kidney-graft function.1 The investigation was initiated on March 20, 2012, and registered
Autor:
Marjan Huizing, Monique B. Perry, Diana L. Fitzpatrick, Mark D. Murphey, Lynn H. Gerber, Wendy J. Introne, Isa Bernardini, Paul D. Anderson, William A. Gahl, Chanika Phornphutkul, Yair Anikster
Publikováno v:
New England Journal of Medicine. 347:2111-2121
Alkaptonuria, caused by mutations in the HGO gene and a deficiency of homogentisate 1,2-dioxygenase, results in an accumulation of homogentisic acid (HGA), ochronosis, and destruction of connective tissue. There is no effective therapy for this disor
Autor:
Trish M. Perl, Joseph J. Cullen, Michael A. Pfaller, Deborah Sheppard, Loreen A. Herwaldt, Pamela French, Richard P. Wenzel, Jennifer Twombley, M. Bridget Zimmerman
Publikováno v:
New England Journal of Medicine. 346:1871-1877
Patients with nasal carriage of Staphylococcus aureus have an increased risk of surgical-site infections caused by that organism. Treatment with mupirocin ointment can reduce the rate of nasal carriage and may prevent postoperative S. aureus infectio