Zobrazeno 1 - 10
of 106
pro vyhledávání: ''
Autor:
Lavannya Pandit, Julia Garcia-Diaz, Gerard J. Criner, Benjamin Kramer, Jamie Freedman, Maria F. González-Lara, Rachel Baden, Linda Yau, Jian Han, Shalini V. Mohan, Miriam L Cameron, Reena Shah, Carlos Salama, Victoria Chávez, Martha Mekebeb-Reuter, Ferdinando Lima de Menezes, Jeffrey D. Neidhart, Emma Kaplan-Lewis, W. Reiss, Beverly Assman
Publikováno v:
New England Journal of Medicine
The New England Journal of Medicine
The New England Journal of Medicine
Background Coronavirus disease 2019 (Covid-19) pneumonia is often associated with hyperinflammation. Despite the disproportionate incidence of Covid-19 among underserved and racial and ethnic minority populations, the safety and efficacy of the anti
Autor:
Yuping Dong, Robert Hamlin, Daniel Gaudet, Erik S.G. Stroes, Lesley J. Burgess, Robert Pordy, Nagwa Khilla, Shazia Ali, C. Ebenbichler, Seth J. Baum, Robert S. Rosenson, Vladimir Son
Publikováno v:
New England journal of medicine, 383(24), 2307-2319. Massachussetts Medical Society
Patients with refractory hypercholesterolemia, who have high low-density lipoprotein (LDL) cholesterol levels despite treatment with lipid-lowering therapies at maximum tolerated doses, have an increased risk of atherosclerosis. In such patients, the
Autor:
Sebastian Unizony, Zsofia D. Drobni, Cory A. Perugino, Deborah S. Collier, Janeth Yinh, Chana A. Sacks, Brian C. Healy, John H. Stone, Ana D. Fernandes, Michael Dougan, Allison K. Scherer, Kathryn Bowman, Harry M Schrager, Crystal M. North, Michael K. Mansour, Nina Lin, Eric A. Meyerowitz, Sarah Nikiforow, Amna Zafar, Rachel Wallwork, Mark Matza, Yuan Di C. Halvorsen, Jorge Fleisher, Jonathan Dau, Michael D. Pincus, Arthur Y. Kim, Matthew J. Frigault, Brittany Weber, David S. Huckins, Ana Maria Bensaci, Liam Harvey, Ruta Shah, Megan Lockwood, Tara K. Thurber, Pritha Sen, Manish Sagar, Andrea S. Foulkes, Tomas G. Neilan, Zeina Dagher, Nora Horick, Ann E. Woolley, Minna J. Kohler, Naomi Serling-Boyd, Sara R. Schoenfeld, Matthew Axelrod, Caroline Cubbison, Marcy B. Bolster, Kristin M. D’Silva
Publikováno v:
New England Journal of Medicine
BACKGROUND: The efficacy of interleukin-6 receptor blockade in hospitalized patients with coronavirus disease 2019 (Covid-19) who are not receiving mechanical ventilation is unclear. METHODS: We performed a randomized, double-blind, placebo-controlle
Autor:
Ken, Okumura, Masaharu, Akao, Tetsuro, Yoshida, Masahito, Kawata, Osamu, Okazaki, Shintaro, Akashi, Kenichi, Eshima, Kimihiko, Tanizawa, Masayuki, Fukuzawa, Takuya, Hayashi, Masahiro, Akishita, Gregory Y H, Lip, Takeshi, Yamashita
Publikováno v:
Okumura, K, Akao, M, Yoshida, T, Kawata, M, Okazaki, O, Akashi, S, Eshima, K, Tanizawa, K, Fukuzawa, M, Hayashi, T, Akishita, M, Lip, G Y H & Yamashita, T 2020, ' Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation ', New England Journal of Medicine, vol. 383, no. 18, pp. 1735-1745 . https://doi.org/10.1056/NEJMoa2012883
BACKGROUND: Implementation of appropriate oral anticoagulant treatment for the prevention of stroke in very elderly patients with atrial fibrillation is challenging because of concerns regarding bleeding. METHODS: We conducted a phase 3, multicenter,
Autor:
David A. Margolis, Conn M. Harrington, Krischan J Hudson, Christine L. Talarico, Pedro Cahn, Simon Vanveggel, Fritz Bredeek, Gary Richmond, Wim Louis Julien Parys, Jenny Huang, Giuliano Rizzardini, Herta Crauwels, Vadim Pokrovsky, Parul Patel, Peter Williams, Joseph M. Mrus, Jaime-Federico Andrade-Villanueva, Graham H R Smith, Susan Swindells, Susan L. Ford, Yeon Sook Kim, Gulam H Latiff, Kimberly Y. Smith, Axel Baumgarten, Mar Masiá, Vasiliki Chounta, William Spreen
Publikováno v:
New England Journal of Medicine. 382:1112-1123
Background Simplified regimens for the treatment of human immunodeficiency virus type 1 (HIV-1) infection may increase patient satisfaction and facilitate adherence. Methods In this phase ...
Autor:
Evan Loh, Joven Gonong, Anita Das, Monica Popescu, Judith N. Steenbergen, Roman Stets, Paul C. McGovern, Andrzej Madej, Paul B. Eckburg, Amy Manley, Evan Tzanis, William Nseir, Ismail Mitha, Lynne Garrity-Ryan, Courtney Kirsch
Publikováno v:
New England Journal of Medicine. 380:517-527
Background Omadacycline, a new once-daily aminomethylcycline antibiotic agent that can be administered intravenously or orally, reaches high concentrations in pulmonary tissues and is acti...
Autor:
Julie E. Buring, JoAnn E. Manson, Bubes, Walter C. Willett, Shari S. Bassuk, Friedenberg G, William G. Christen, I-Min Lee, Christine M. Albert, Copeland T, Ridge C, Samia Mora, David Gordon, Derek Dagostino, Edward Giovannucci, Nancy R. Cook, Heike Gibson
Publikováno v:
New England Journal of Medicine. 380:23-32
Background Higher intake of marine n−3 (also called omega-3) fatty acids has been associated with reduced risks of cardiovascular disease and cancer in several observational studies. Whether supplementation with n−3 fatty acids has such effects i
Autor:
Sibylle Loibl, Seock-Ah Im, Carla Giorgetti, Angela DeMichele, Massimo Cristofanilli, Fabrice Andre, Nicholas C. Turner, Marco Colleoni, H. Iwata, Dennis J. Slamon, Cynthia Huang Bartlett, Sunil Verma, Xin Huang, Igor Bondarenko, Nadia Harbeck, Sherene Loi, Kathy Puyana Theall, Jungsil Ro, Norikazu Masuda
Publikováno v:
New England Journal of Medicine. 379:1926-1936
Background The cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor palbociclib, in combination with fulvestrant therapy, prolongs progression-free survival among patients with hormone-receptor–positive, human epidermal growth factor receptor 2 (HER2
Autor:
Kolb, Martin, Raghu, Ganesh, Wells, Athol U, Behr, Jürgen, Richeldi, Luca, Schinzel, Birgit, Quaresma, Manuel, Stowasser, Susanne, INSTAGE Trial Investigators, Benjamin Bondue, Bondue, Benjamin, Martinez, Fernando J
Publikováno v:
The New England journal of medicine, 379 (18
Background Nintedanib is an approved treatment for idiopathic pulmonary fibrosis (IPF). A subgroup analysis of a previously published trial suggested that sildenafil may provide benefits regarding oxygenation, gas exchange as measured by the diffusio
Autor:
Lucie Blondeau, Mylène Provencher, Olivier F. Bertrand, Aldo P. Maggioni, José López-Sendón, Jean-Claude Tardif, François Roubille, Simon Kouz, Wolfgang Koenig, Marie-Pierre Dubé, Rafael Diaz, Andreas Orfanos, Reda Ibrahim, Denis Angoulvant, Petr Ostadal, Fausto J. Pinto, Jean Grégoire, Ghassan S. Kiwan, Marie-Claude Guertin, David D. Waters, Marc-André Lavoie, David Rhainds, Colin Berry, Habib Gamra, Philippe L. L’Allier
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
New England Journal of Medicine
New England Journal of Medicine, 2019, ⟨10.1056/NEJMoa1912388⟩
The New England journal of medicine, vol 381, iss 26
New England Journal of Medicine, Massachusetts Medical Society, 2019, ⟨10.1056/NEJMoa1912388⟩
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
New England Journal of Medicine
New England Journal of Medicine, 2019, ⟨10.1056/NEJMoa1912388⟩
The New England journal of medicine, vol 381, iss 26
New England Journal of Medicine, Massachusetts Medical Society, 2019, ⟨10.1056/NEJMoa1912388⟩
Copyright © 2019 Massachusetts Medical Society. All rights reserved.
Background: Experimental and clinical evidence support the role of inflammation in atherosclerosis and its complications. Colchicine is an orally administered, potent antiinfl
Background: Experimental and clinical evidence support the role of inflammation in atherosclerosis and its complications. Colchicine is an orally administered, potent antiinfl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245444c6724cffe5dc69b81d63e21083
https://eprints.gla.ac.uk/204890/1/204890.pdf
https://eprints.gla.ac.uk/204890/1/204890.pdf