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Autor:
Samuel Klein, Richard I. Stein, Jeramie D. Watrous, Rob Knight, J. Christopher Eagon, Jun Yoshino, Mohit Jain, Mihoko Yoshino, Dominic N. Reeds, Brandon D. Kayser, Shaina R. Eckhouse, Bruce W. Patterson, Kenneth B. Schechtman
Publikováno v:
The New England journal of medicine, vol 383, iss 8
N Engl J Med
N Engl J Med
BACKGROUND: Some studies have suggested that in people with type 2 diabetes, Roux-en-Y gastric bypass has therapeutic effects on metabolic function that are independent of weight loss. METHODS: We evaluated metabolic regulators of glucose homeostasis
Autor:
Martin Kaufmann, Stefanie Weber, David E. Prosser, Tulay Guran, Karl P. Schlingmann, Anne M. Wingen, Joachim Misselwitz, Henry Fehrenbach, Glenville Jones, Joost G. J. Hoenderop, Günter Klaus, Ulrike John, René J. M. Bindels, Andrew Irwin, Martin Konrad, Caroline Goos, Eberhard Kuwertz-Bröking
Publikováno v:
The New England Journal of Medicine, 365, 410-21
The New England Journal of Medicine, 365, 5, pp. 410-21
The New England Journal of Medicine, 365, 5, pp. 410-21
Item does not contain fulltext BACKGROUND: Vitamin D supplementation for the prevention of rickets is one of the oldest and most effective prophylactic measures in medicine, having virtually eradicated rickets in North America. Given the potentially
Autor:
Liesl Page-Shipp, Jenny Allen, Paul Meyvisch, Karel de Beule, Alexander S. Pym, Rene Krause, Andreas H. Diacon, Johan Verbeeck, Koen Andries, Martin P. Grobusch, Roxana Rustomjee, Nacer Lounis, Rolf van Heeswijk, R. F. Patientia, Juan Carlos Palomino, Christoffel Pistorius, Amour Venter, David F Mc Neeley, Tine De Marez, Wim Parys, Gavin J. Churchyard, Mampedi Bogoshi
Publikováno v:
The New England journal of medicine
New England journal of medicine, 360(23), 2397-2405. Massachussetts Medical Society
New England journal of medicine, 360(23), 2397-2405. Massachussetts Medical Society
Background The diarylquinoline TMC207 offers a new mechanism of antituberculosis action by inhibiting mycobacterial ATP synthase. TMC207 potently inhibits drug-sensitive and drug-resistant Mycobacterium tuberculosis in vitro and shows bactericidal ac
Autor:
Pugazhendhi Srinivasan, S. Venkataraman, Henry J. Binder, Graeme P. Young, Pratap Dash, Balakrishnan S. Ramakrishna
Publikováno v:
New England Journal of Medicine. 342:308-313
Although standard glucose-based oral rehydration therapy corrects the dehydration caused by cholera, it does not reduce the diarrhea. Short-chain fatty acids, which are produced in the colon from nonabsorbed carbohydrates, enhance sodium absorption.
Publikováno v:
New England Journal of Medicine. 333:1-4
Ingestion of a large dose of the milk sugar lactose--for example, the 50-g load in 1 liter of milk--causes symptoms such as abdominal pain, diarrhea, bloating, and flatulence in the majority of people with lactose malabsorption. It is uncertain wheth
Publikováno v:
New England Journal of Medicine. 332:1251-1255
The risk of microalbuminuria in patients with insulin-dependent diabetes mellitus (IDDM) is thought to depend on the degree of hyperglycemia, but the relation between the degree of hyperglycemia and urinary albumin excretion has not been defined.We m
Autor:
Barbara I. Brown, Rick Selby, Thomas E. Starzl, Eduardo J. Yunis, Andreas G. Tzakis, Ross S. Kendall
Publikováno v:
New England Journal of Medicine. 324:39-42
Type IV glycogen storage disease is a rare autosomal recessive disorder (also called Andersen’s disease1 or amylopectinosis) in which the activity of branching enzyme alpha-1, 4-glucan: alpha-1, 4-glucan 6-glucosyltransferase is deficient in the li
Publikováno v:
New England Journal of Medicine. 297:1107-1110
The effectiveness of sucrose and glucose electrolyte solutions as fluid replacement in cholera and severe diarrheas from other causes was compared. Subjects in this study which took place in Bangladesh were of both sexes and were aged 5 years or olde
Publikováno v:
New England Journal of Medicine. 302:645-650
The incidence of retinopathy was assessed in 188 diabetic and 284 nondiabetic Pima Indian adults six years after an initial examination had shown each to be free of retinopathy. Exminations included direct ophthalmoscopy through dilated pupils. The i
Autor:
Douglas B. McGill, Joseph D. Motto
Publikováno v:
New England Journal of Medicine. 291:278-282
Between 1966 and 1972 hepatitis developed in 12 young male workers exposed to an epoxy resin 4, 4′diaminodiphenylmethane (methylenedianiline). This compound produces cholestasis and hepatic necrosis in many animals and caused the so-called Epping j