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pro vyhledávání: ''
Autor:
Thomas, Rauen, Frank, Eitner, Christina, Fitzner, Claudia, Sommerer, Martin, Zeier, Britta, Otte, Ulf, Panzer, Harm, Peters, Urs, Benck, Peter R, Mertens, Uwe, Kuhlmann, Oliver, Witzke, Oliver, Gross, Volker, Vielhauer, Johannes F E, Mann, Ralf-Dieter, Hilgers, Jürgen, Floege, Ellen, Irmler-Mercier
Publikováno v:
New England Journal of Medicine. 373:2225-2236
BACKGROUND: The outcomes of immunosuppressive therapy, when added to supportive care, in patients with IgA nephropathy are uncertain. METHODS: We conducted a multicenter, open-label, randomized, controlled trial with a two-group, parallel, group-sequ
Autor:
Todd A. Conner, Robert F. Reilly, William C. Duckworth, Linda F. Fried, Peter A. McCullough, Stephen L. Seliger, Mary Brophy, Nicholas V. Emanuele, Paul M. Palevsky, Peter Guarino, Theresa Z. O'Connor, Suzanne Watnick, Jane H. Zhang, Stuart R. Warren, David J. Leehey, Peter Peduzzi
Publikováno v:
New England Journal of Medicine. 369:1892-1903
Background Combination therapy with angiotensin-converting–enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) decreases proteinuria; however, its safety and effect on the progression of kidney disease are uncertain. Methods We provide
Autor:
Bradley A, Bart, Steven R, Goldsmith, Kerry L, Lee, Michael M, Givertz, Christopher M, O'Connor, David A, Bull, Margaret M, Redfield, Anita, Deswal, Jean L, Rouleau, Martin M, LeWinter, Elizabeth O, Ofili, Lynne W, Stevenson, Marc J, Semigran, G Michael, Felker, Horng H, Chen, Adrian F, Hernandez, Kevin J, Anstrom, Steven E, McNulty, Eric J, Velazquez, Jenny C, Ibarra, Alice M, Mascette, Eugene, Braunwald, M, Kwak
Publikováno v:
New England Journal of Medicine. 367:2296-2304
A B S T R AC T Background Ultrafiltration is an alternative strategy to diuretic therapy for the treatment of patients with acute decompensated heart failure. Little is known about the efficacy and safety of ultrafiltration in patients with acute dec
Autor:
Erick B. Edwards, Patrick S. Kamath, W. Ray Kim, Joanne T. Benson, Russell H. Wiesner, Scott W. Biggins, Walter K. Kremers, Terry M. Therneau
Publikováno v:
New England Journal of Medicine. 359:1018-1026
BACKGROUND Under the current liver-transplantation policy, donor organs are offered to patients with the highest risk of death. METHODS Using data derived from all adult candidates for primary liver transplantation who were registered with the Organ
Autor:
Fabrizio Veglia, Stefano Galli, Emilio Assanelli, Piero Montorsi, Antonio L. Bartorelli, Monica De Metrio, Gianfranco Lauri, Giancarlo Marenzi, Franco Fabbiocchi, Jeness Campodonico, Ivana Marana, Marco Grazi
Publikováno v:
New England Journal of Medicine. 354:2773-2782
Background Patients with acute myocardial infarction undergoing primary angioplasty are at high risk for contrast-medium–induced nephropathy because of hemodynamic instability, the need for a high volume of contrast medium, and the lack of effectiv
Autor:
Zheng Rong Liu, Xun Zhang, Guo Hua Zhang, Fan Fan Hou, Di Xie, Ren Wen Geng, Jian Ping Jiang, Guo Bao Wang, Min Liang, Weiru Zhang, Ping Yan Chen
Publikováno v:
New England Journal of Medicine. 354:131-140
Angiotensin-converting-enzyme inhibitors provide renal protection in patients with mild-to-moderate renal insufficiency (serum creatinine level, 3.0 mg per deciliter or less). We assessed the efficacy and safety of benazepril in patients without diab
Autor:
Gianfranco Lauri, Franco Fabbiocchi, Emilio Assanelli, Piero Montorsi, Giancarlo Marenzi, Daniela Trabattoni, Jeness Campodonico, Ivana Marana, Marco Grazi, Antonio L. Bartorelli
Publikováno v:
New England Journal of Medicine. 349:1333-1340
background Nephropathy induced by exposure to radiocontrast agents, a possible complication of percutaneous coronary interventions, is associated with significant in-hospital and longterm morbidity and mortality. Patients with preexisting renal failu
Autor:
Preben G. Berthelsen, Paul E. Marik
Publikováno v:
New England Journal of Medicine. 373:2686-2687
To the Editor: In the July 30 issue of the Journal, Niemann and colleagues published their investigation on therapeutic hypothermia in deceased organ donors and kidney-graft function.1 The investigation was initiated on March 20, 2012, and registered
Autor:
Nicholas J. White, Ly Van Chuong, Nguyen Hoan Phu, Jeremy Farrar, Tran Thi Hong Chau, Tran Tinh Hien, Pham Phu Loc, Nguyen Thi Hoang Mai, Christopher G. Winearls, Nicholas P. J. Day
Publikováno v:
New England Journal of Medicine. 347:895-902
BACKGROUND: In some parts of the world, peritoneal dialysis is widely used for renal replacement in acute renal failure. In resource-rich countries, it has been supplanted in recent years by hemodialysis and, most recently, by hemofiltration and asso
Publikováno v:
New England Journal of Medicine. 337:230-237
Elevated plasma homocysteine levels are a risk factor for coronary heart disease, but the prognostic value of homocysteine levels in patients with established coronary artery disease has not been defined.We prospectively investigated the relation bet