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Autor:
Dorling, L., Carvalho, S., Allen, J., Gonzalez-Neira, A., Luccarini, C., Wahlstrom, C., Pooley, K.A., Parsons, M.T., Fortuno, C., Wang, Q., Bolla, M.K., Dennis, J., Keeman, R., Alonso, M.R., Alvarez, N., Herraez, B., Fernandez, V., Nunez-Torres, R., Osorio, A., Valcich, J., Li, M., Torngren, T., Harrington, P.A., Baynes, C., Conroy, D.M., Decker, B., Fachal, L., Mavaddat, N., Ahearn, T., Aittomaki, K., Antonenkova, N.N., Arnold, N., Arveux, P., Ausems, M.G.E.M., Auvinen, P., Becher, H., Beckmann, M.W., Behrens, S., Bermisheva, M., Bialkowska, K., Blomqvist, C., Bogdanova, N.V., Bogdanova-Markov, N., Bojesen, S.E., Bonanni, B., Borresen-Dale, A.L., Brauch, H., Bremer, M., Briceno, I., Bruning, T., Burwinkel, B., Cameron, D.A., Camp, N.J., Campbell, A., Carracedo, A., Castelao, J.E., Cessna, M.H., Chanock, S.J., Christiansen, H., Collee, J.M., Cordina-Duverger, E., Cornelissen, S., Czene, K., Dork, T., Ekici, A.B., Engel, C., Eriksson, M., Fasching, P.A., Figueroa, J., Flyger, H., Forsti, A., Gabrielson, M., Gago-Dominguez, M., Georgoulias, V., Gil, F., Giles, G.G., Glendon, G., Garcia, E.B.G., Alnaes, G.I.G., Guenel, P., Hadjisavvas, A., Haeberle, L., Hahnen, E., Hall, P., Hamann, U., Harkness, E.F., Hartikainen, J.M., Hartman, M., He, W., Heemskerk-Gerritsen, B.A.M., Hillemanns, P., Hogervorst, F.B.L., Hollestelle, A., Ho, W.K., Hooning, M.J., Howell, A., Humphreys, K., Idris, F., Jakubowska, A., Jung, A., Kapoor, P.M., Kerin, M.J., Khusnutdinova, E., Kim, S.W., Ko, Y.D., Kosma, V.M., Kristensen, V.N., Kyriacou, K., Lakeman, I.M.M., Lee, J.W., Lee, M.H., Li, J.M., Lindblom, A., W.Y. lo, Loizidou, M.A., Lophatananon, A., Lubinski, J., MacInnis, R.J., Madsen, M.J., Mannermaa, A., Manoochehri, M., Manoukian, S., Margolin, S., Martinez, M.E., Maurer, T., Mavroudis, D., McLean, C., Meindl, A., Mensenkamp, A.R., Michailidou, K., Miller, N., Taib, N.A.M., Muir, K., Mulligan, A.M., Nevanlinna, H., Newman, W.G., Nordestgaard, B.G., Ng, P.S., Oosterwijk, J.C., Park, S.K., Park-Simon, T.W., Perez, J.I.A., Peterlongo, P., Porteous, D.J., Prajzendanc, K., Prokofyeva, D., Radice, P., Rashid, M.U., Rhenius, V., Rookus, M.A., Rudiger, T., Saloustros, E., Sawyer, E.J., Schmutzler, R.K., Schneeweiss, A., Schurmann, P., Shah, M., Sohn, C., Southey, M.C., Surowy, H., Suvanto, M., Thanasitthichai, S., Tomlinson, I., Torres, D., Truong, T., Tzardi, M., Valova, Y., Asperen, C.J. van, Dam, R.M. van, Ouweland, A.M.W. van den, Kolk, L.E. van der, Veen, E.M. van, Wendt, C., Williams, J.A., Yang, X.H.R., Yoon, S.Y., Zamora, M.P., Evans, D.G., Hoya, M. de la, Simard, J., Antoniou, A.C., Borg, A., Andrulis, I.L., Chang-Claude, J., Garcia-Closas, M., Chenevix-Trench, G., Milne, R.L., Pharoah, P.D.P., Schmidt, M.K., Spurdle, A.B., Vreeswijk, M.P.G., Benitez, J., Dunning, A.M., Kvist, A., Teo, S.H., Devilee, P., Easton, D.F., Breast Canc Assoc Consortium
Publikováno v:
New England Journal of Medicine, 384(5), 428-439. MASSACHUSETTS MEDICAL SOC
Dorling, L, Carvalho, S, Allen, J, González-Neira, A, Luccarini, C, Wahlström, C, A. Pooley, K, T. Parsons, M, Fortuno, C, Wang, Q, K. Bolla, M, Dennis, J, Keeman, R, Alonso, M R, Álvarez, N, Herraez, B, Fernandez, V, Núñez-Torres, R, Osario, A, Valchich, J, Li, M, Törngren, T, A. Harrington, P, Baynes, C, M. Conroy, D, Decker, B, Fachal, L, Mavaddat, N, Ahearn, T, Aittomäki, K, N. Antonenkova, N, Arnold, N, Arveux, P, G.E.M Ausems, M, Auvinen, P, Becher, H, W. Beckmann, M, Behrens, S, Bermisheva, M, Białkowska, K, Blomqvist, C, V. Bogdanova, N, Bogdanova-Markov, N, E. Bojesen, S, Bonanni, B, Børresen-Dale, A-L, Brauch, H, Bremer, M, Briceno, I, Brüning, T, Burwinkel, B & Cameron, D A 2021, ' Breast cancer risk genes: association analysis in more than 113,000 women ', New England Journal of Medicine . https://doi.org/10.1056/NEJMoa1913948
N Engl J Med
New England Journal of Medicine, 384(5), 428-439. Massachussetts Medical Society
Breast Cancer Association Consortium 2021, ' Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women ', New England Journal of Medicine, vol. 384, no. 5, pp. 428-439 . https://doi.org/10.1056/NEJMoa1913948
The New England Journal of Medicine, 384, 5, pp. 428-439
New England Journal of Medicine
New England Journal of Medicine, 384(5), 428-439. MASSACHUSETTS MEDICAL SOCIETY
The New England Journal of Medicine, 384, 428-439
Dorling, L, Carvalho, S, Allen, J, González-Neira, A, Luccarini, C, Wahlström, C, A. Pooley, K, T. Parsons, M, Fortuno, C, Wang, Q, K. Bolla, M, Dennis, J, Keeman, R, Alonso, M R, Álvarez, N, Herraez, B, Fernandez, V, Núñez-Torres, R, Osario, A, Valchich, J, Li, M, Törngren, T, A. Harrington, P, Baynes, C, M. Conroy, D, Decker, B, Fachal, L, Mavaddat, N, Ahearn, T, Aittomäki, K, N. Antonenkova, N, Arnold, N, Arveux, P, G.E.M Ausems, M, Auvinen, P, Becher, H, W. Beckmann, M, Behrens, S, Bermisheva, M, Białkowska, K, Blomqvist, C, V. Bogdanova, N, Bogdanova-Markov, N, E. Bojesen, S, Bonanni, B, Børresen-Dale, A-L, Brauch, H, Bremer, M, Briceno, I, Brüning, T, Burwinkel, B & Cameron, D A 2021, ' Breast cancer risk genes: association analysis in more than 113,000 women ', New England Journal of Medicine . https://doi.org/10.1056/NEJMoa1913948
N Engl J Med
New England Journal of Medicine, 384(5), 428-439. Massachussetts Medical Society
Breast Cancer Association Consortium 2021, ' Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women ', New England Journal of Medicine, vol. 384, no. 5, pp. 428-439 . https://doi.org/10.1056/NEJMoa1913948
The New England Journal of Medicine, 384, 5, pp. 428-439
New England Journal of Medicine
New England Journal of Medicine, 384(5), 428-439. MASSACHUSETTS MEDICAL SOCIETY
The New England Journal of Medicine, 384, 428-439
BACKGROUNDGenetic testing for breast cancer susceptibility is widely used, but for many genes,evidence of an association with breast cancer is weak, underlying risk estimatesare imprecise, and reliable subtype-specific risk estimates are lacking.METH
Autor:
Janet E. Olson, Elizabeth S. Burnside, Chi Gao, Heather Eliassen, Paul L. Auer, Chunling Hu, Argyrios Ziogas, Brian D. Carter, James M. Hodge, Lynn Rosenberg, Jack A. Taylor, Rohan Gnanaolivu, Amy Trentham-Dietz, Mia M. Gaudet, Katherine L. Nathanson, David E. Goldgar, Irene M. Ong, Susan M. Gapstur, Katie M. O'Brien, Alpa V. Patel, Charles Kooperberg, Rulla M. Tamimi, David J. Hunter, Christine B. Ambrosone, Celine M. Vachon, Nicholas J. Boddicker, Hoda Anton-Culver, Esther M. John, Song Yao, Jeffrey N. Weitzel, Dale P. Sandler, Christopher G. Scott, Susan L. Neuhausen, Eric C. Polley, Josh Klebba, Jenna Lilyquist, Polly A. Newcomb, Kimberly A. Bertrand, Raed Samara, Kun Y. Lee, Susan M. Domchek, Steven N. Hart, Elisa V. Bandera, Huiyan Ma, Leslie Bernstein, Sara Lindstroem, Sonya Reid, Christopher A. Haiman, Loic Le Marchand, Hongyan Huang, Tuya Pal, Peter Kraft, Eric J. Jacobs, Siddhartha Yadav, Julie R. Palmer, Allison W. Kurian, Fergus J. Couch, Tricia Lindstrom, Clarice R. Weinberg, Jie Na
Publikováno v:
N Engl J Med
The New England journal of medicine, vol 384, iss 5
The New England journal of medicine, vol 384, iss 5
BACKGROUND: Population-based estimates of the risk of breast cancer associated with germline pathogenic variants in cancer-predisposition genes are critically needed for risk assessment and management in women with inherited pathogenic variants. METH
Autor:
Suresh Goyal, Balasubramanian Sundaram, Kulandaivel Murugiah, Sunita Bidari, Prasantajyoti Mohanty, Gagandeep Kang, Rajendra P Gorthi, Mannancheril A Mathew, Vineeta Gupta, Nayana P Nair, Hemant Jain, Suraj Chawla, Hemanthkumar Boopathy, Gopinath Vinayagamurthy, Rajkumar Gupta, Samarasimha N Reddy, Pramod Sharma, Sambandan Kumaravel, Muthukumaran Jagannatham, Mohan D Gupte, Saroj Sathpathy, Ira Praharaj, Raghul Maniam, Ashwitha Shenoy, Jacqueline E Tate, Venkata R Mohan, Girish K C Purushothaman, Geeta Gathwala, Sudhir Babji, Hiranya Mohanty, Jayanta K Goswami, Sowmiya Senthamizh, Vittal Mohan, Madhu Gupta, Umesh D Parashar, Krishna B Goru, Priyadarishini Dorairaj, Tarun J K Jacob, Rashmi Arora, Nirmal Kumar Mohakud, Padmalatha Pamu, Rajib Kumar Ray, Sidhartha Giri, Ashish Wakhlu, Manohar Badur, Suhasini Mekala, Mrutunjay Dash, Rajamani Gurusamy, Varunkumar Thiyagarajan, Bhaskar Reddy
Publikováno v:
The New England Journal of Medicine
A three-dose, oral rotavirus vaccine (Rotavac) was introduced in the universal immunization program in India in 2016. A prelicensure trial involving 6799 infants was not large enough to detect a small increased risk of intussusception. Postmarketing
Autor:
Jennifer L. Beauregard, Dana Meaney-Delman, Bailey Wallace, Charles E. Rose, Lauren Head Zauche, Emily E. Petersen, Titilope Oduyebo, Ashley N. Smoots, Sascha R. Ellington, Allen J. Wilcox, Jun Ju, Christine K. Olson, Shin Y. Kim
Publikováno v:
The New England Journal of Medicine
mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion In this updated analysis from the CDC v-safe pregnancy registry, the cumulative risk of pregnancy loss at 6 to less than 20 weeks of gestatio...
Publikováno v:
New England Journal of Medicine
The New England Journal of Medicine
The New England Journal of Medicine
Open Schools, Covid-19, and Child and Teacher Morbidity This letter includes data on children and teachers in Sweden who were admitted to ICUs with Covid-19 between March 1 and June 30, 2020. There...
Publikováno v:
The New England Journal of Medicine
Vaccination and Household Transmission of SARS-CoV-2 In this study involving household contacts of persons with laboratory-confirmed Covid-19, the risk of household transmission was 40 to 50% lower...
Autor:
Jeffrey Lipman, Bradley Wibrow, René Zellweger, Claire Forsdyke, Stephen Honeybul, Frederick B. Rogers, Jenny Chamberlain, Elizabeth Geelhoed, Cyrus Edibam, Alan Kop, Tomas Corcoran, Kwok M. Ho, Sudhakar Rao, Anthony Holley, Ross I. Baker, Philip Misur
Publikováno v:
Canadian Journal of Surgery
Whether early placement of an inferior vena cava filter reduces the risk of pulmonary embolism or death in severely injured patients who have a contraindication to prophylactic anticoagulation is not known.In this multicenter, randomized, controlled
Autor:
Mandy Vogel, Tobias Lipek, Ulrike Spielau, Eberhard Keller, Roland Pfäffle, Wieland Kiess, Mandy Geserick, Ruth Gausche, A. Körner
Publikováno v:
New England Journal of Medicine. 379:1303-1312
The dynamics of body-mass index (BMI) in children from birth to adolescence are unclear, and whether susceptibility for the development of sustained obesity occurs at a specific age in children is important to determine.To assess the age at onset of
Autor:
Patrick F. Chinnery
Legislation passed by the House of Lords in 2015 enabled mitochondrial replacement in the United Kingdom for the prevention of severe mitochondrial diseases. Regulation was delegated to the Human Fertilisation and Embryology Authority (HFEA) which gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b041b70650a1a7dd908c2f6e51eb2a
Autor:
SUNDAY CLARK, Emil Ylikallio, MARIAN MUCHADA, Cristina Hobeanu, Saima Bashir Viturro, David Tirschwell, Amy Ying Xin Yu, Matthew Vibbert, Jiaying Zhang, Javier Sotoca, Ricardo Rigual, Gerrit M. Grosse, Laurent Derex, Daniel Guisado-Alonso, Angel Ois, Naresh Mullaguri, Fernanda Bellolio, Laurie Gutmann, Sudeepta Dandapat, Joseph Carrera, POL CAMPS-RENOM, Patricia Martínez-Sánchez, Hayrapet Kalashyan, Brent Becker, Elena Meseguer, Shubhabrata Das, Alejandro Martinez-Domeño, Michelle Leppert, Paulina Sergot, Amie Hsia, Marc Malkoff, Sami Curtze, Roland Faigle, X. Michelle Androulakis, Freimuth Brunner, Ashish Kulhari, Alexandra Reynolds, Neal Parikh, Ivan Marinkovic, Marion Buckwalter, Nicholas Morris, Justin Mazzillo, Philippa Lavallée, Vincent Thijs, Joan Martí-Fàbregas, Jason Mathew, Jaume Roquer Gonzalez, Thalia Field, Tissa Wijeratne, Theodore Wein, Starane Shepherd
Publikováno v:
The New England journal of medicine, vol 379, iss 3
BackgroundCombination antiplatelet therapy with clopidogrel and aspirin may reduce the rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient ischemic attack (TIA). A trial of combination antiplatelet therapy in