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Autor:
Dan L. Stewart, David J. Durand, Richard J. Martin, Avital Cnaan, Mark L. Hudak, Roberta A. Ballard, Dennis E. Mayock, Philip L. Ballard, Sandra R. Wadlinger, Eric C. Eichenwald, Asha R. Puri, Jeffrey D. Merrill, Sergio G. Golombek, Stephen E. Welty, Michele C. Walsh, Anna Maria Hibbs, Roderic H. Phibbs, Donald R. Null, William E Truog, Jeanette M. Asselin, Christine E. Coburn, Sherry E. Courtney, Xianqun Luan
Publikováno v:
New England Journal of Medicine. 355:343-353
Bronchopulmonary dysplasia in premature infants is associated with prolonged hospitalization, as well as abnormal pulmonary and neurodevelopmental outcome. In animal models, inhaled nitric oxide improves both gas exchange and lung structural developm
Autor:
Preben G. Berthelsen, Paul E. Marik
Publikováno v:
New England Journal of Medicine. 373:2686-2687
To the Editor: In the July 30 issue of the Journal, Niemann and colleagues published their investigation on therapeutic hypothermia in deceased organ donors and kidney-graft function.1 The investigation was initiated on March 20, 2012, and registered
Publikováno v:
New England Journal of Medicine. 330:1036-1040
Previous studies suggest that vascular endothelial function may be impaired in essential hypertension. Although muscarinic agonists dilate blood vessels by releasing an endothelium-derived relaxing factor closely related to nitric oxide, nitroprussid
Publikováno v:
New England Journal of Medicine. 328:399-405
The adult respiratory distress syndrome is characterized by pulmonary hypertension and right-to-left shunting of venous blood. We investigated whether inhaling nitric oxide gas would cause selective vasodilation of ventilated lung regions, thereby re
Publikováno v:
New England Journal of Medicine. 305:72-75
IN patients with chronic renal failure who are undergoing hemodialysis, arterial oxygen tension (PaO2) falls when a dialysis solution containing acetate is used.1 2 3 4 It has been suggested that hypoxemia results from altered pulmonary ventilation-p
Autor:
John T. Reeves, Norbert F. Voelkel, Warren H. Toews, Simon L. James, Robert C. Murphy, Kurt R. Stenmark
Publikováno v:
New England Journal of Medicine. 309:77-80
Persistent pulmonary hypertension of the newborn is a syndrome consisting of severe hypoxemia and pulmonary hypertension that appears within hours of birth. Since certain leukotrienes (C4, D4, and E4) are known to produce some of the features of pers